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Keratinocyte growth factor-2 and autologous serum potentiate the regenerative effect of mesenchymal stem cells in cornea damage in rats

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International Journal of Ophthalmology(English edition) 2014年第2期7卷 211-219页

作者： Ferda Alpaslan Pinarli Gülsen Okten Umit Beden Tunc Fisgin Mehmet Kefeli Nurten Kara Feride Duru leman tomak Department of Medical Biology and Genetics Faculty of Medicine Ondokuz Mayis University Department of Ophthalmology Faculty of MedicineOndokuz Mayis University Department of Pediatric Hematology Faculty of MedicineOndokuz Mayis University Department of Pathology Faculty of Medicine Ondokuz Mayis University Department of Medical Biostatistics Faculty of MedicineOndokuz Mayis University

AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells(MSCs)cultured with or without keratinocyte growth factor(KGF-2)and autologous serum(AS)on amniotic membrane(AM).Many patients are blind and devastated by severe ocular surface diseases due to limbal stem cell *** marrow-derived MSCs are potential sources for cellbased tissue engineering to repair or replace the corneal tissue,having the potential to differentiate to epithelial ***:The study included 5 groups each including 10 female'Sprague Dawley'rats in addition to20 male rats used as bone marrow *** I rats received AM+MSCs,Group II rats AM+MSCs cultured with KGF-2,Group III rats AM+MSCs cultured with KGF-2+AS,Group IV rats only AM and Group V rats,*** was derived from blood drawn from male rats and bone marrow was obtained from the femur and tibia bones of the same *** effect was evaluated with clinical,histopathological and immunohistochemical *** engraftment was demonstrated via detection of donor genotype(Y+)in the recipient tissue(X)with polymerase chain ***:Corneal healing was significantly better in Groups I-III rats treated with MSC transplantation compared to Group IV and Group V rats with supportive treatment *** best results were obtained in Group III rats with 90%transparency,70%lack of neovascularization,and 100%epithelium damage limited to less than 1/4 of ***:We suggest that culture of MSCs with KGF-2 and AS on AM is effective in corneal repair in case of irreversible damage to limbal stem cells.

关键词： corneal wound healing mesenchymal stem cells keratinocyte growth factor-2 autologous serum amniotic membrane

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Squeezing Properties of Even Coherent States in a Finite-Dimensional Hilbert Space

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Chinese Physics Letters 1994年第7期11卷 424-427页

作者： ZHU Jiuyun KUANG leman Department of Physics Hu‘nan Normal UniversityChangsha 410081

Even coherent states (ECSs) of a finite-dimensional Hilbert space harmonic oscillator (FDHSHO) are constructed *** properties of them are *** quadrature squeezing and the amplituded-squared squeezing of these states are investigated in *** is found that ECSs of the FDHSHO exhibit not only the quadrature squeezing but also the amplituded-squeezing.

关键词： quadrature Even states

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Nondestructive discrimination of Greenberger-Horne-Zeilinger-basis states via two-qubit parity detection

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Science China(Physics,Mechanics & Astronomy) 2014年第10期57卷 1848-1853页

作者： WANG XinWen TANG ShiQing KUANG leman Department of Physics and Electronic Information Science Hengyang Normal University Key Laboratory of Low-Dimensional Quantum Structures and Quantum Control of Ministry of Education and Department of PhysicsHunan Normal University

We propose new methods to construct universal Greenberger-Horne-Zeilinger(GHZ)-state analyzers without destroying the qubits by using two-qubit parity gates. The idea can be applied to any physical systems where the two-qubit parity gate can be *** also investigate the feasibility of nondestructively distinguishing the GHZ-basis states for photonic qubits with such an *** nondestructive GHZ-state analyzers can act as generators of GHZ entangled states and are expected to find useful applications for resource-saving quantum information processing.

关键词： nondestructive GHZ-state analyzer two-qubit parity gate photon

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Coherent State of N Components and Cycle Representation

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Chinese Physics Letters 1995年第3期12卷 132-135页

作者： ZENG Gaojian KUANG leman LI Jinhui Department of Physics Hunan Normal UniversityHunan 410006

In this paper,we construct a type of coherent state with N components,and use it to span cycle representations of the Lie algebras SU(2),SU(1,l)and the Lit:superalgebra OSP(1,2).The method for constructing cycle repre... 详细信息

关键词： cycle constructing coherent

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Even and Odd Q-coherent State Representations of the Q-deformed Heisenberg-Weyl Algebra

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Chinese Physics Letters 1992年第12期9卷 629-632页

作者： WANG Fabo KUANG leman Department of Physics Hunan Normal UniversityChangsha 410006 Department of Physics Changsha Normal University of Water Resources and Electric PowerChangsha 410077

We construct explicitly even and odd q-coherent *** q-coherent states are introduced in terms of the q-functions defined in the *** is shown that the even and odd q-coherent states form a kind of representations of the q-deformed Heisenberg-Weyl algebra which is realized in the form of matrix q-differential operators in the even and odd q-coherent state *** also analyse some different between the even and odd q-CSs and the usual even and odd CSs.

关键词： space. coherent deformed

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Multiparametric analysis of colorectal cancer immune responses

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World Journal of Gastroenterology 2018年第27期24卷 2995-3005页

作者： Julia KH leman Sarah K Sandford Janet L Rhodes Roslyn A Kemp Department of Microbiology and Immunology University of Otago

Colorectal cancer(CRC) is a heterogeneous disease, with a diverse and plastic immune cell infiltrate. These immune cells play an important role in regulating tumour growth-progression or elimination. Some populations of cells have a strong correlation with disease-free survival, making them useful prognostic markers. In particular, the infiltrate of CD3^+ and CD8^+ T cells into CRC tumours has been validated worldwide as a valuable indicator of patient prognosis. However, the heterogeneity of the immune response, both between patients with tumours of different molecular subtypes, and within the tumour itself, necessitates the use of multiparametric analysis in the investigation of tumour-specific immune responses. This review will outline the multiparametric analysis techniques that have been developed and applied to studying the role of immune cells in the tumour, with a focus on colorectal cancer. Because much of the data in this disease relates to T cell subsets and heterogeneity, we have used T cell populations as examples throughout. Flow and mass cytometry give a detailed representation of the cells within the tumour in a single-cell suspension on a per-cell basis. Imaging technologies, such as imaging mass cytometry, are used to investigate increasing numbers of markers whilst retaining the spatial and structural information of the tumour section and the infiltrating immune cells. Together, the analyses of multiple immune parameters can provide valuable information to guide clinical decision-making in CRC.

关键词： Colorectal cancer Flow cytometry Immune cells Multiparametric analysis Immunohistochemistry Mass cytometry Microscopy

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Geopark Concept as a Tool to Promote Geoheritage Conservation:Case Study from Langkawi Global Geopark,Malaysia

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地学前缘 2009年第S1期16卷 294-295页

作者： Tanot Unjah Mohd Shafeea leman Ibrahim Komoo Institute for Environment and Development(LESTARI) University Kebangsaan Malaysia

Malaysia embarks on geoheritage conservation in the late 1970’s with initial listing of important geological sites for *** the late 1980’s the idea of having a more systematic approach was discussed that leading towards the introduction of a better described ***,very little of these endeavours and efforts came to reality in protecting and conserving geoheritage in the *** introduction of geopark concept to the country in 2000 has brought positive responses from

关键词： geopark geoheritage conservation geotourism

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The omnivorous predator Macrolophus pygmaeus,a good candidate for the control of both greenhouse whitefly and poinsettia thrips on gerbera plants

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Insect Science 2020年第3期27卷 510-518页

作者： Ada leman Barbara L.Ingegno Luciana Tavella Arne Janssen Gerben J.Messelink Wageningen University&Research Business Unit Greenhouse HorticultureBleiswijkthe Netherlands Dipartimento di Scienze Agrarie Forestall e Alimentari(DISAFA)ULF Entomologia Generate e ApplicataUniversity of TorinoGrugliasco(TO)Italy IBED Department of Evolutionary and Population BiologyUniversity of AmsterdamAmsterdamthe Netherlands

The poinsettia thrips Echinothrips americanus Morgan is a relatively new pest that has spread rapidly worldwide and causes serious damage in both vegetable and ornamental *** this study,we investigated if and how effective this pest can be controlled in gerbera by the omnivorous predator Macrolophus pygmaeus(Rambur).Because herbivores on plants can interact through a shared predator,we also investigated how poinsettia thrips control is affected by the presence of the greenhouse whitefly Trialeurodes vaporariorum(Westwood),a pest that commonly coexists with *** in *** laboratory studies,we found that the predator *** fed on both pests when offered *** tests showed a clear preference of the predators for plants infested by whiteflies but not by *** a greenhouse experiment,densities of both pests on single gerbera plants were reduced to very low levels by the predator,either with both pests present together or ***,predator‐mediated effects between whiteflies and thrips played only a minor *** plant feeding of the shared predator probably reduced the dependence of predator survival and reproduction on the densities of the two pests,thereby weakening potential predator‐mediated ***,*** is a good candidate for biological control of both pests in ***,further research is needed to investigate pest control at larger scales,when the pests can occur on different plants.

关键词： apparent competition biological control Echinothrips americanus pest interactions prey preference Trialeurodes vaporariorum

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Vertex angles effects in the energy absorption of axially crushed kenaf fibre-epoxy reinforced elliptical composite cones

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Defence Technology（防务技术） 2018年第4期14卷 327-335页

作者： Mohamed Alkateb S.M.Sapuan Z.leman M.R.Ishak Mohammad Jawaid Department of Mechanical and Manufacturing Engineering Universiti Putra Malaysia Laboratory of Bio Composite Technology Institute of Tropical Forestry and Research Products (INTROP)Universiti Putra Malaysia Aerospace Manufacturing Research Centre (AMRC) Universiti Putra Malaysia Departments of Aerospace Engineering Universiti Putra Malaysia

Experimental quasi-static crushing tests were conducted by using a universal testing machine format kenaf-epoxy composite elliptical cones. The work focused on the vertex angle's effects on energy absorption capability; the vertex angles vary from 0° to 24° in 6 increments. The failure modes of the kenaf fibre epoxy composite elliptical cones were observed utilising delegate photos taken during the quasistatic crushing test. Load-deformation curves and deformation histories of typical specimens are presented and discussed. Moreover, the effects of cone vertex angles on the load carrying capacity and the energy absorption capability are also discussed. The results show that the energy absorption abilities significantly influence the ellipticity vertex angle as the load carrying capacity. We concluded that the quasi-static axial crushing behaviour of elliptical mat laminated composite cones is strongly affected by their structural geometry and the specific energy absorbed by the composite elliptical cones with vertex angles of 6°, 12°, 18°, and 24°, which is more than an elliptical cone with the vertex angle of 0°(the elliptical tube) at any given deformation. However, the specific energy absorption for the elliptical composite cone showed a positive correlation, i.e., the more the angle increased, the more energy was absorbed. In this regard, an elliptical composite cone with a 24° angle exhibited the best energy absorption capability.

关键词： Kenaf fibres Composite materials Elliptical cone Vertex angle Collapsible Energy absorption

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Effect of fibre orientations on the mechanical properties of kenaf–aramid hybrid composites for spall-liner application

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Defence Technology（防务技术） 2016年第1期12卷 52-58页

作者： R.YAH AYA S.M.SAPUAN M.JAWAID Z.leman E.S.ZAINUDIN Department of Mechanical and Manujacturing Engineering Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia Science and Technology Research Institutejbr Dejence (STRIDE) 43000 Kajang Selangor Malaysia Laboratory of Biocomposite Technology Institute of Tropical Forestry and Forest Products (INTROP) Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia Aerospace Manujacturing Research Centre (AMRC) Faculty of Engineering Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia Department of Chemical Engineering College of Engineering King Saud University Riyadh Saudi Arabia

This paper presents the effect of kenaf fibre orientation on the mechanical properties of kenaf–aramid hybrid composites for military vehicle's spall liner application. It was observed that the tensile strength of woven kenaf hybrid composite is almost 20.78% and 43.55% higher than that of UD and mat samples respectively. Charpy impact strength of woven kenaf composites is 19.78% and 52.07% higher than that of UD and mat kenaf hybrid composites respectively. Morphological examinations were carried out using scanning electron microscopy. The results of this study indicate that using kenaf in the form of woven structure could produce a hybrid composite material with high tensile strength and impact resistance properties.

关键词：芳纶复合材料材料力学性能纤维取向红麻应用剥落编织复合材料扫描电子显微镜

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