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Inaugural Seizures Revealing COVID-19 in an Immunocompetent Infant at the University Teaching Hospital (UTH) of Bouaké

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Open Journal of Pediatrics 2022年第4期12卷 678-687页

作者： Djakaridja Kone Iburaima Alamun Akanji Martine Tatiana Yapo Kokora Junior Gawa Juliette Kadiane-Oussou leioh romeo adou Jean Marie Karidioula Yapo Thomas Aba Kouadio Vincent Asse Ouffoue Kra Department of Infectious and Tropical Diseases University Teaching Hospital of Bouaké Bouaké C&ocirc te d’Ivoire COVID-19 Care Center University Teaching Hospital of Bouaké Bouaké C&ocirc te d’Ivoire Department of Pediatrics University Teaching Hospital of Bouaké Bouaké C&ocirc te d’Ivoire Department of Bacteriology and Virology University Teaching Hospital of Bouaké Bouaké C&ocirc te d’Ivoire

Introduction: Children are likely to present with atypical and non-specific clinical manifestations of COVID-19, unlike adults. The aim of this observation is to identify the difficulties related to the diagnosis and the curative and preventive management of SARS-CoV-2 infection in children. Observation: This is a 15-month-old infant admitted for febrile seizures. The interrogation revealed signs evolving 48 hours before his admission marked by post-prandial vomiting, wet cough, hypotonia, food refusal, incessant crying, fever, and seizures. His antecedents can be summed up as an uneventful pre- and per-natal period, good eating habits, good psychomotor and staturo-ponderal development, and outdated vaccination. The physical and paraclinical examination made it possible to retain the diagnosis of severe pneumonia. The initial management consisted of oxygenation, hydroelectrolyte intake, antibiotic therapy, and neurosedation. The evolution 3 days later was marked by a worsening of the clinical features, and the hypothesis of infection with SARS-CoV-2 was raised. The nasopharyngeal swab for COVID-19 RT-PCR performed was positive. The infant was isolated in the intensive care unit, where he received oxygen therapy with a mask, enteral nutrition, antibiotic therapy, corticosteroid therapy, and adequate nursing. The evolution was favorable 48 hours later. In addition, his asymptomatic mother and 14-year-old brother were placed in isolation after a positive RT-PCR COVID-19 test. Her father who was very often away from home for professional reasons was negative for COVID-19 RT-PCR. They all four live in the same 3-room house. Conclusion: Childhood COVID-19 has many facets. Clinicians should think about it in the face of any infectious manifestation, in order to avoid delays in treatment and improve the prognosis.

关键词： COVID-19 Children Atypical Manifestations SARS-CoV-2 Bouaké

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Psychological Experience of Mothers of Children with Sickle Cell Disease Followed at the Pediatric Department of Bouaké University Teaching Hospital

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Open Journal of Pediatrics 2024年第1期14卷 149-163页

作者： Akanji Iburaima Alamun Aka-Tanoh Koko Aude Hélène Yao Kouassi Christian adou leioh romeo Sahi Gnantin Josette Landryse Amani Ehi Alexise Eleonore Boune Aboulaye Asse Kouadio Vincent Paediatrics Department Bouaké University Teaching Hospital Bouaké C&#244te d’Ivoire

Introduction: Sickle cell disease has physical and emotional repercussions on the child and his family. The aim of this study was to describe the psychosocial experiences of mothers of children with sickle cell disease in order to improve the overall care of the child. Methods: This was a descriptive cross-sectional study carried out in the pediatrics department of Bouaké University Teaching Hospital from June to September 2023. It focused on mothers of major sickle-cell-affected children followed up in the pediatrics department of the Bouaké University Teaching Hospital. The variables studied were sociodemographic, psychological, social and economic. Results: Of the 40 mothers surveyed, 15% were not in school and 32.5% were unemployed. For them, sickle cell disease was of natural (genetic) origin in 90% and supernatural in 10%. They stated that the child had an average age of 36 months (extremes 7 and 108 months) when the disease was discovered. And 52% of them were satisfied with the way the disease was clearly and completely announced. Following the announcement, the questioned mothers said they had felt shock (35%), sadness (31.7%), guilt (23.3%) and discouragement (10%). Anxiety and depression were experienced by 77.5% and 22.5% respectively. In 60% of cases, they stated that the disease was incurable, and the outcome was fatal in 2.5% of cases. The child’s illness was a source of problems in the home in 25% of cases, represented by arguments in 92% and divorce in 8%. In 97.5% of cases, the mother told her family and friends about the child’s illness. In 90% of cases, the mother and child benefited from psychological support from family and friends. Conclusion: Sickle cell disease is a serious illness with a psychological and social impact on mothers. We recommend psychological support for mothers from the moment of diagnosis and throughout follow-up.

关键词： Psychosocial Experience Sickle Cell Disease Côte d’Ivoire

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Epidemiological, Clinical, Therapeutic, Evolutionary and Prognostic Aspects of Children with COVID-19 in Bouaké(Côte d’Ivoire)

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Advances in Infectious Diseases 2022年第2期12卷 216-229页

作者： Kone Djakaridja Kadiane-Oussou Juliette Akanji Iburaima Alamun Yapo Martine Tatiana adou leioh romeo Karidioula Jean Marie Aba Yapo Thomas Asse Kouadio Vincent Kra Ouffoue Department of Infectious and Tropical Diseases University and Teaching Hospital of Bouaké Bouaké Ivory Coast Department of Pediatric University and Teaching Hospital of Bouaké Bouaké Ivory Coast

Context: Compared to adults, there are relatively few studies on pediatric COVID-19 due to the high rate of asymptomatic or paucisymptomatic forms. The aim of this study is to determine the epidemiological, clinical, therapeutic, evolutionary and prognostic aspects of COVID-19 infection in children. Patients and Methods: This was a prospective analytical study carried out from February 27, 2021 to January 27, 2022 at the COVID-19 Care Center of the Infectious and Tropical Diseases Department of the Bouaké University Teaching Hospital. The study population consisted of all children under the age of 16, seen in consultation and/or hospitalized with a positive COVID-19 RT-PCR. Data analysis was performed with Epi Info 7 software. The statistical tests used were the chi-square test and Fisher’s exact test depending on the conditions of validity with a significance threshold of p Results: Out of 955 patients received at the COVID-19 Care Center in Bouaké, there were 56 children (26 boys/30 girls), or, a prevalence of 5.86%. The mean age was 9.18 years ± 4.48 [extremes 3 months and 15 years]. Children over the age of 11 accounted for 48.21% of cases. They were contact cases in 35.71% and the contact person was the mother in 75% of cases. The main reasons for screening were cough (67.86%), fever (25%) and sneezing (21.43%). The pathological histories were asthma (83.33%), heart disease (33.33%) and sickle cell disease (16.67%). The medical examination revealed 6 cases of children in vital distress. The care consisted of home confinement for simple cases (89.29%) and hospitalization for cases presenting with vital distress (10.71%). The duration of confinement or hospitalization was between 10 and 15 days in 83.93% of cases. No cases of death were noted. The factors associated with the occurrence of symptomatic forms were age (p = 0.028), pathological history (p Conclusion: The proportion of pediatric cases of COVID-19 is low with a predominance during the season of harmatt

关键词： Epidemiology Coronavirus SARS-Cov2 Children Bouaké

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COVID-19 in Bouake (Côte D’Ivoire): Comparative Study of the Epidemiological, Clinical, Therapeutic, Evolutionary and Prognostic Aspects in Younger and Elderly Patients

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Advances in Infectious Diseases 2022年第2期12卷 312-327页

作者： Kone Djakaridja Kadiane-Oussou Juliette Akanji Iburaima Alamun Yapo Martine Tatiana Kouamé Kouamé Gilles Renaud Karidioula Jean Marie adou leioh romeo Kone Famoussa Sule Mutiyu Akanbi Soumahoro Namory Junior Aba Yapo Thomas Kra Ouffoue Department of Infectious and Tropical Diseases University and Teaching Hospital of Bouaké Bouaké Ivory Coast COVID-19 Care Center University and Teaching Hospital of Bouaké Bouaké Ivory Coast Department of Internal Medecine University and Teaching Hospital of Bouaké Bouaké Ivory Coast

Introduction: The clinical manifestations of many diseases vary with age, and older people often do not show typical symptoms of the disease. The present study aims to compare the epidemiological, clinical, therapeutic and evolutionary aspects of elderly patients with COVID-19 compared to young adult patients and to identify risk factors for mortality. Patients and Methods: This was a retrospective single-center analytical study conducted from January 27, 2021 to January 27, 2022 at the COVID-19 Care Center of the Infectious and Tropical Diseases Department of the Bouaké University Teaching Hospital. The study population consisted of all patients aged at least 18 years seen in consultation and/or hospitalized with a positive COVID-19 RT-PCR. The patients were divided into two groups: younger patients (Results: Of a total of 779 patients, 644 (82.7%) were young. The median age of all patients was 41 years (IQR 32 - 54, extreme 18 and 96). Of all the patients 38.5% had a comorbidity. Compared to younger patients, chronic heart disease (61.7% vs 21.5%;p Conclusion: Elderly people with COVID-19 have a different clinical presentation from younger, characterized by more atypical symptoms. Mortality risk factors are age, dyspnoea, impaired consciousness and fever. It is therefore necessary to act on its various factors to improve the prognosis of COVID-19 in this age group.

关键词： Epidemiology Coronavirus SARS-Cov2 Age Bouaké

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Etiologies and Prognostic Factors of Dyspnea in Infants at the University Hospital Center (CHU) of Bouaké (Ivory Coast)

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Open Journal of Pediatrics 2023年第3期13卷 313-323页

作者： Yenan John Patrick Yeboua Yao Kossonou Roland Yao Kouassi Christian Aka-Tanoh Koko Aude Hélène Akanji Iburaima Alamun Sahi Gnantin Josette Landryse adou leioh romeo Amani Ehi Alexise Eleonore Avi-Siallou Christelle Honorine Asse Kouadio Vincent Department of Pediatrics Universiy Teaching Hospital of Bouake Bouake Ivory Coast

Identify the epidemiological characteristics, etiologies and evolutionary aspects of dyspnea in infants. This was a retrospective study of infants hospitalized for dyspnea from January 1 to December 31, 2020. The parameters studied were sex, age, origin, vaccination status, existence of underlying pathology. Underlying, the diagnosis and the evolutionary modalities. Data analysis and processing were possible using Word, Excel and EPI info version 7 software. We retained 152 infants. The sex ratio was 1.34 and the median age was 4 months. Vaccines according to expanded immunization program (EPI) were up to date in 76.32%. The main antecedents with risk identified were malnutrition, hypotrophy at birth, interventricular communication. The pathologies observed were low acute respiratory diseases in 90.79%, ENT diseases in 04.60% and cardiac diseases in 03.95%. The median length of hospitalization was 4 days. Infants who died accounted for 15.13%. The median age of infants who died was 4 months. The median time to onset of death was 1.63 days. The risk factors for death were age < 6 months (p = 0.003;CI [1.27;9.33]), outdated vaccines (p = 0.012;CI [1.18;5.17]), history with risk (p = 0.031;CI [1.02;4.54]). Dyspnea in infants remains a concern in our service. Reducing mortality involves developing procedures for the management of lower respiratory ailments, continuous staff training and strengthening the technical platform.

关键词： Infants Dyspnea Prognostic Factors

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Type VI Aplasia Cutis Congenita: About a Case Report at University Teaching Hospital of Bouaké

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Open Journal of Pediatrics 2023年第1期13卷 146-152页

作者： Yao Kouassi Christian Yeboua Yao Kossonou Roland Yenan John Patrick Akanji Iburaima Alamun adou leioh romeo Sahi Gnantin Josette Landryse Amani Ehi Alexise Eleonore Avi-Siallou Christelle Honorine Aka-Tanoh Koko Aude Hélène Asse Kouadio Vincent Department of Pediatrics Universiy Teaching Hospital of Bouaké Bouaké Ivory Coast

Introduction: Aplasia cutis congenita is a rare congenital dermatosis of which type VI represents the Bart’s syndrome. The aim of this case is to describe the epidemiological, clinical, therapeutic and prognostic characteristics of this condition in a country with limited resources, for the improvement of prognosis and professional practice. Observation: This is a eutrophic newborn, born at term by vaginal delivery, who presented at birth with a unilateral absence of skin on the anteromedial aspect of the right leg starting from the knee and extending to the medial aspect of the right foot, with a dystrophy of the nail of the right big toe without any other visible physical malformation. The evolution was marked at D3 of life by the appearance of bullae on the right hand and elbow as well as on the posterior aspect of the neck, making epidermolysis bullosa suspect. The mother was 38 years old, 8th gesture, 7th pare with history of consanguinity and collodion baby. The association of a localized congenital absence of skin on the lower limbs, epidermolysis bullosa and a nail anomaly led to the diagnosis of congenital cutaneous aplasia of type VI of Frieden’s classification or Bart’s syndrome. The evolution was satisfactory on the 7th day of life with the beginning of scarring. The management was medical. The outcome was unfavorable with the appearance of sepsis and hemorrhage leading to death. Conclusion: Although rare, the clinical diagnosis of Bart’s syndrome is simple. However, the management is complex and the prognosis is reserved. To improve this prognosis, the treatment must guarantee excellent control of the infectious and hemorrhagic risks, an adhesion and good therapeutic compliance by the parents and a rigorous monitoring.

关键词： Aplasia Cutis Congenita Bart’s Syndrome Newborn Prognosis Côte d’Ivoire

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Knowledge, Attitudes and Practices of Mothers Regarding Exclusive Breastfeeding in Rural Areas of Brobo (Côte d’Ivoire)

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Open Journal of Pediatrics 2021年第4期11卷 694-705页

作者： Aka-Tanoh Koko Aude-Hélène Avi-Siallou Christelle Honorine Yeboua Kossonou Roland Yao Kouassi Christian Akandji Iburaima adou leioh Roméo Sahi Gnantin Landryse Amani Ehi Alexise Asse Kouadio Vincent Department of the University Hospital of Bouaké Bouaké C&ocirc te d'Ivoire

Introduction:In C?te d’Ivoire, despite awareness raising among mothers by health authorities and health care providers, the exclusive breastfeeding rate is still low, 23%. This rate seems even lower in rural areas. The objective of the study was to evaluate the knowledge, attitudes and practices of mothers regarding exclusive breastfeeding for the reduction of malnutrition in rural areas. Methods: This was a descriptive and analytical cross-sectional study conducted in Brobo from July to September 2020. It included consenting mothers of infants aged 0 to 24 months. Mothers’ knowledge, attitudes and practice were assessed by an anonymous structured questionnaire with a performance threshold set at 75%. Factors associated with exclusive breastfeeding were investigated by the Chi-square test at the 5% level of significance. Results: The average age of the 183 mothers was 25 years (extremes 13 and 49 years). They were primigravida (33%) and had a low socioeconomic level (84%). The mothers knew the definition of exclusive breastfeeding (33%). They knew that breastfeeding promoted ideal infant growth (64%) and protected against diarrhea and infection (18%). They also knew that breastfeeding reduced the mother’s risk of cancer (16%) and strengthened the mother-infant bond (7%). The mothers interviewed stated that they had put the baby to the breast within the first hour after delivery in 2% and 63% of them gave the baby colostrum. Mothers were confident about breastfeeding (91%) and exclusive breastfeeding until 6 months of age represented 9%. The factor associated with lack of knowledge of exclusive b

关键词： Exclusive Breastfeeding Rural Environment Infant Brobo

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