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Invasive Thymoma with Endobronchial Polypoid Growth

Open Journal of Respiratory Diseases 2015年第4期5卷 71-74页

作者： Samira Aouadi Emna Braham Ayda Ayadi Houda Gharsalli Asma Zidi Adel Marghli Sonia Maalej leila douik el gharbi Respiratory Department D Aberrahmene Mami Hospital University of Medicine Tunis Tunis Tunisia Laboratory of Pathology Aberrahmene Mami Hospital University of Medicine Tunis Tunis Tunisia Department of Radiology Aberrahmene Mami Hospital University of Medicine Tunis Tunis Tunisia Department of Thoracic Surgery Aberrahmene Mami Hospital University of Medicine Tunis Tunis Tunisia

Thymomas are the most common neoplasms of the mediastinum. It is common that thymoma invades neighboring structures in the thorax, but direct polypoid tumor growth into the airway is extremely rare. We report a rare case of invasive thymoma with polypoid endobronchial growth in a 66-year-old woman. Computed tomography demonstrated an anterior mediastinal tumor which extended into the right upper lobe. Endoscopic examination revealed a polypoid tumor which occluded the right upper bronchus. A biopsy specimen obtained from the intraluminal mass was very suggestive of thymoma. The patient had no parathymic syndrome. The tumor was resected with the right upper lobe. The final post-operative tissue findings confirmed a type B2 thymoma of the World Health Organisation classification.

关键词： Invasive Thymoma Anterior Mediastinal Tumor Bronchoscopy Endobronchial Growth

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Interstitial Lung Diseases Associated with Connective Tissue Pathologies: Radiologic Features

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Open Journal of Respiratory Diseases 2019年第4期9卷 112-122页

作者： Houda Gharsalli Monia Attia Sawssen Hantous-Zannad Imen Sahnoun Sonia Maalej leila douik el gharbi Henda Neji Khaoula Ben Miled-Mrad Department of Pulmonology Abderrahmane Mami Hospital Ariana Tunisia University of Tunis el Manar Tunis Tunisia Department of Radiology Abderrahmane Mami Hospital Ariana Tunisia

Introduction: The high resolution computed tomography (HRCT) is an important part in the diagnostic approach of interstitial lung disease (ILD) associated with connective tissue diseases (CTD) by providing detailed information on the elementary lesion and the radiological pattern of ILD. Aim: to point out the role of HRCT in the diagnosis of ILD associated with CTD (ILD-CTD). Methods: A Retrospective descriptive study was conducted between 2008 and 2017. Data of 24 patients presenting ILD-CTD were collected. A review of HRCT was performed by a radiologist without knowledge of the CTD. Results: Predominant elementary lesion of ILD associated with dermatomyositis (9 cases) was ground glass opacity (n = 9) followed by consolidation (n = 6). Non Specific Interstitial Pneumonia (NSIP) was the most reported pattern (5 cases). Ground glass opacity was also the predominant elementary lesion for the 2 cases of scleroderma and in Sjögren’s syndrome (4 cases/5). NSIP was the predominant radiological presentation in these two CTD. Lymphoid interstitial pneumonia revealed Sjögren’s syndrome in one case. In rheumatoid arthritis (6 cases), the elementary HRCT lesions were irregular interlobular septal thickening (n = 4) and honeycombing (n = 4) consistent with Usual Interstitial Pneumonia (UIP) in 2 cases. Similarly UIP has been described for the 2 patients with lupus and mixed connective tissue disease. Conclusion: HRCT plays an important role in the management of ILD-CTD. Description of the HRCT elementary lesions and the radiological pattern of ILD can be helpful for CTD’s diagnosis.

关键词： Interstitial Lung Diseases Connective Tissue Diseases Computed Tomography Imaging Diagnosis

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Mature Teratoma Revealed by an Encysted Pleural Effusion

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Open Journal of Respiratory Diseases 2021年第2期11卷 84-89页

作者： Houda Gharsalli Monia Attia Sarra Zairi Imen Sahnoun Aida Ayadi Henda Neji Sonia Maalej leila douik elgharbi Department of Pulmonology Abderrahmane Mami Hospital Ariana Tunisia University of Tunis el Manar Tunis Tunisia Department of Radiology Abderrahmane Mami Hospital Ariana Tunisia Department of Thoracic and Cardiovascular Surgery Abderrahmane Mami Hospital Ariana Tunisia Department of Pathology Abderrahmane Mami Hospital Ariana Tunisia

A 32-year-old patient with no previous history was admitted for chest pain, dyspnea, appetite and weight loss. Chest X-ray revealed an opacity involving the lower two-thirds of the right hemithorax, suggestive of a pleural effusion. Because of the absence of fluid return even after ultrasound-guided thoracentesis, a Chest Computed tomography was required showing a heterogeneous anterior mediastinal mass with soft tissue, fat, fluid and calcifications associated with extensive encysted fluid collection in the right hemithorax. A video-assisted mini-thoracotomy revealed a mediastinal tumor firmly attached to the thymus with a cystic wall lined by squamous epithelium and sebaceous gland composed of respiratory tissue, adipose tissue, cartilage,

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