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Resources Chemicals and Materials 2023年第3期2卷 245-251页

作者： Shunsheng Yang Zhihong Zhang Xueqing Qiu lei zhong Jiahong Huang Huiting Zhang Jianhui Ma Qingwei Meng Xihong Zu Wenli Zhang Guangdong Provincial Key Laboratory of Plant Resources Biorefinery School of Chemical Engineering and Light IndustryGuangdong University of Technology(GDUT)100 Waihuan Xi RoadPanyu DistrictGuangzhou 510006China School of Advanced Manufacturing Guangdong University of Technology(GDUT)JieyangJieyang 522000China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory(Rongjiang Laboratory) Jieyang 515200China

Hard carbon is considered as the most commercially applicable anode for sodium-ion *** has the characteristics of sustainable,low cost,high carbon content(>60%)and abundant oxygen functional groups,which is expected to be used as a promising candidate precursor for low-cost hard *** structure and electrochemical performances of hard carbons could be regulated by adjusting carbonization *** microstructure and electrochemical performance of LDHC anode are highly dependent on the carbonization *** carbonization temperature could reduce specific surface area and improve initial coulombic *** slope and plateau capacity of the LDHC anode could also be adjusted by changing the carboniza-tion *** LDHC prepared at 1200℃ showed the best sodium-ion storage performance,with an initial coulombic efficiency of 78.9%and a reversible sodium-ion storage capacity of 284.7 mAh g^(−1).

关键词： Lignin Hard carbon Anode Sodium-ion battery

Pathomorphological study on location and distribution of Kupffer cells in hepatocellular carcinoma

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World Journal of Gastroenterology 2003年第9期9卷 1946-1949页

作者： Kai Liu Xu He Xue-zhong lei Lian-San Zhao Hong Tang Li Liu Bing-Jun lei Division of Molecular Biology of Infectious Disease Key Laboratory of Biotherapy of Human Disease,Ministry of Education,West China Hospital of Sichuan University,Chengdu 610041,Sichuan Province,China Division of Molecular Biology of Infectious Disease Key Laboratory of Biotherapy of Human Disease Ministry of Education West China Hospital of Sichuan University Chengdu 610041 Sichuan Province China.

AIM: To clarify the location and distribution of Kupffer cells in hepatocellular carcinoma (HCC), and to investigate their role in ***: Kupffer cells were immunohistochemically stained by streptavadin-peroxidase conjugated method (S-P). The numbers of Kupffer cells in cancerous, para-cancerous and adjacent normal liver tissues of 48 HCCs were comparatively ***: The mean number of Kupffer cells in cancerous,para-cancerous and adjacent normal liver tissues was 12.7±6.8, 18.1±8.2 and 18.9±7.9 respectively. The number of Kuppfer cells in cancerous tissues was significantly lower than that in para-cancerous tissues (t=2.423, P＜0.05) and adjacent normal liver tissues (t=2.52t, P＜0.05). As tumor size increased, the number of Kupffer cells in cancerous tissues significantly decreased (F=4.61, P＜0.05). Moreover,there was also a significant difference in the number of Kupffer cells among well-differentiated, moderately-differentiated and poorly-differentiated cases(F＝4.49, P＜0.05).CONCLUSION: This study suggests that decrease of Kupffer cells in HCCs may play an important role in the carcinogenesis of HCC, the number of Kupffer cells in HCC is closely related to the size and differentiation grade of the tumor.

关键词：肝细胞癌枯否细胞位置分布发病机制

Exendin-4 inhibits high-altitude cerebral edema by protecting against neurobiological dysfunction

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Neural Regeneration Research 2018年第4期13卷 653-663页

作者： zhong-lei Sun Xian-Feng Jiang Yuan-Chi Cheng Ying-Fu Liu Kai Yang Shuang-Long Zhu Xian-Bin Kong Yue Tu Ke-Feng Bian Zhen-Lin Liu Xu-Yi Chen Affiliated Hospital of Logistics University of Chinese People's Armed Police Forces Institute of Traumatic Brain Trauma and Neurological of CAPF Neurotrauma Repair Key Laboratory of Tianjin Tianjin China Jinzhou Medical University Jinzhou Liaoning Province China Tianjin Medical University Tianjin China Central Hospital of Fengxian District of Shanghai Shanghai China Logistics University of People's Armed Police Force Tianjin China The No. 2 Hospital of Nanjing Nanjing Jiangsu Province China Tianjin University of Traditional Chinese Medicine Tianjin China

The anti-inflammatory and antioxidant effects of exendin-4（Ex-4） have been reported ***,whether（Ex-4） has anti-inflammatory and antioxidant effects on high-altitude cerebral edema（HACE） remains poorly *** this study,two rat models of HACE were established by placing rats in a hypoxic environment with a simulated altitude of either 6000-or 7000-m above sea level（MASL） for 72 *** altitude of 7000 MASL with 72-hours of hypoxia was found to be the optimized experimental paradigm for establishing HACE ***,in rats where a model of HACE was established by introducing them to a 7000 MASL environment with 72-hours of hypoxia treatment,2,10 and,100 μg of Ex-4 was intraperitoneally *** open field test and tail suspension test were used to test animal *** methods were used to detect change in inflammatory ***-eosin staining was performed to determine pathological changes to brain ***/dry weight ratios were used to measure brain water *** blue leakage was used to determine blood-brain barrier ***-linked immunosorbent assay（ELISA） was performed to measure markers of inflammation and oxidative stress including superoxide dismutase,glutathione,and malonaldehyde values,as well as interleukin-6,tumor necrosis factor-alpha,cyclic adenosine monophosphate levels in the brain *** blot analysis was performed to determine the levels of occludin,ZO-1,SOCS-3,vascular endothelial growth factor,EPAC1,nuclear factor-kappa B,and *** results demonstrate that Ex-4 preconditioning decreased brain water content,inhibited inflammation and oxidative stress,alleviated brain tissue injury,maintain blood-brain barrier integrity,and effectively improved motor function in rat models of *** findings suggest that Ex-4 exhibits therapeutic potential in the treatment of HACE.

关键词： high-altitude cerebral edema exendin-4 cyclic adenosine monophosphate EPACI suppressor of cytokine signaling 3 vascular endothelial growth factor hypoxia inflammation oxidative stress

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基于网络信息的潜在恐怖分子挖掘模型仿真

计算机仿真 2014年第7期31卷 313-316页

作者：钟磊新疆财经大学统计与信息学院新疆乌鲁木齐830012

在潜在恐怖分子信息识别的研究中,通过网络信息进行反恐是一项十分重要的工作。网络不同信息中隐藏着与恐怖信息相关的人员,网络上各种信息种类较多,在网络上的语言存在较大变化,并且可伪装,传统的数据挖掘方法应用到网络信息分析过程中... 详细信息

在潜在恐怖分子信息识别的研究中,通过网络信息进行反恐是一项十分重要的工作。网络不同信息中隐藏着与恐怖信息相关的人员,网络上各种信息种类较多,在网络上的语言存在较大变化,并且可伪装,传统的数据挖掘方法应用到网络信息分析过程中,对潜在恐怖分子进行挖掘的过程中,受到信息伪装等因素的影响,固定的网络信息挖掘关联模式被打破或被掩饰,造成人员挖掘效果不准确。提出利用人工免疫网络信息的潜在恐怖分子挖掘方法。对相关网络信息进行模糊聚类处理,计算网络信息数据到聚类中心的距离,并对所有的网络信息数据进行有效的更新处理。分别设置网络信息数据中的抗原和抗体,计算上述数据于恐怖分子之间的关联度,计算抗原与抗体的匹配度,并且对上述数据进行变异处理,在网络信息的基础上,实现潜在恐怖分子的识别模型。实验结果表明,利用改进模型进行潜在恐怖分子挖掘,挖掘准确性更强。

关键词：网络信息潜在恐怖分子数据挖掘

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后危机时代完善我国信用评级行业监管的思考

征信 2013年第2期31卷 45-48页

作者：钟磊中国人民银行上海总部上海200120

后危机时代,美国、欧盟等国家和地区纷纷出台改革措施,加强对信用评级行业的监管。通过剖析信用评级监管的理论基础及现实意义,以后危机视角下信用评级业国际监管改革为鉴,重新审视我国信用评级监管现状,提出适合我国信用评级行业发展... 详细信息

后危机时代,美国、欧盟等国家和地区纷纷出台改革措施,加强对信用评级行业的监管。通过剖析信用评级监管的理论基础及现实意义,以后危机视角下信用评级业国际监管改革为鉴,重新审视我国信用评级监管现状,提出适合我国信用评级行业发展的监管政策及建议。

关键词：后危机时代信用评级行业监管

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中西色彩审美中的文化意味

装饰 2005年第9期 96-97页

作者：钟磊浙江树人大学艺术学院

本文从色彩与宗教、色彩与民俗、色彩与等级尊卑三个方面探讨了中西色彩审美中色彩所承载的文化内涵、寓意、象征性及其异同。

关键词：色彩文化意味宗教民俗等级尊卑

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论苏曼殊小说的传奇叙事

新疆大学学报（哲学社会科学版） 2016年第3期44卷 127-131页

作者：仲雷武汉大学文学院湖北武汉430072

"传奇"是中国小说的重要叙事传统,它的影响一直渗透在近现代小说叙事模式的转变上。具有过渡性质的苏曼殊小说,其传奇品格体现在徘徊人与文之间的自叙传奇、对世情书写的浪漫传奇和搜神志异的人事传奇之中。在取奇的叙事模式上,苏曼殊... 详细信息

"传奇"是中国小说的重要叙事传统,它的影响一直渗透在近现代小说叙事模式的转变上。具有过渡性质的苏曼殊小说,其传奇品格体现在徘徊人与文之间的自叙传奇、对世情书写的浪漫传奇和搜神志异的人事传奇之中。在取奇的叙事模式上,苏曼殊采取多样化处理故事情节的方式和"逃离"的形式来构成逻辑序列,使其小说的传奇叙述具有奇而不幻、异而不虚的特质。苏曼殊小说的传奇叙事还呈现出与其它叙事手段混杂的状态,形成传奇与抒情、传统与现代的对立性张力。

关键词：传奇苏曼殊传奇品格取奇模式

耐吉非替尼的HCC827GR细胞的高效诱导及其药理学特性

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中国药理学通报 2016年第9期32卷 1284-1288页

作者：钟磊师健友电子科技大学附属医院四川省人民医院个体化药物治疗四川省重点实验室四川成都610072

目的建立对吉非替尼(gefitinib)耐受的NSCLC细胞株,并观察其药理学特性。方法采用HGF和浓度递增的gefitinib处理HCC827细胞以诱导细胞耐药;MTT法测试细胞活力和药物敏感性;克隆形成和Edu染色验证gefitinib对细胞的生长抑制作用;qRT-PCR... 详细信息

目的建立对吉非替尼(gefitinib)耐受的NSCLC细胞株,并观察其药理学特性。方法采用HGF和浓度递增的gefitinib处理HCC827细胞以诱导细胞耐药;MTT法测试细胞活力和药物敏感性;克隆形成和Edu染色验证gefitinib对细胞的生长抑制作用;qRT-PCR和Western blot实验检测细胞中c-Met表达。结果 HGF的使用可缩短HCC827GR耐药细胞的诱导时间;gefitinib可明显抑制HCC827亲本细胞的细胞活力、克隆形成和细胞增殖,而对HCC827GR细胞的生长抑制作用很弱;HCC827GR细胞c-Met高表达,对c-Met抑制剂高度敏感。结论成功并高效诱导了对gefitinib耐药的HCC827GR细胞,该细胞生长依赖c-Met蛋白活性,对c-Met抑制剂较敏感,可作为c-Met抑制剂的表型筛选模型。

关键词：非小细胞肺癌吉非替尼 c-Met 耐药表型筛选激酶抑制剂

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概念整合理论对《雨中的猫》的认知解读

外国语文 2011年第4期27卷 34-38页

作者：钟蕾四川外语学院出国培训部重庆400031

《雨中的猫》是海明威最优秀的短篇小说之一,其八分之七的深刻主题隐藏于八分之一的简练语言之下。本文试图通过概念整合理论的组合、完善及拓展三种操作过程,形成由多个整合空间组合的网络,凭借概念整合网络层层剖析《雨中的猫》的故... 详细信息

《雨中的猫》是海明威最优秀的短篇小说之一,其八分之七的深刻主题隐藏于八分之一的简练语言之下。本文试图通过概念整合理论的组合、完善及拓展三种操作过程,形成由多个整合空间组合的网络,凭借概念整合网络层层剖析《雨中的猫》的故事背景、叙事结构及主题,解读《雨中的猫》的篇章意义构建过程,揭示海明威八分之七的深刻主题,从而验证概念整合理论对短篇小说的强大解释力,显示其独特的视角。

关键词：认知诗学概念整合背景结构主题

An improved GGNMOS triggered SCR for high holding voltage ESD protection applications

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Chinese Physics B 2015年第10期24卷 591-593页

作者：张帅董树荣吴晓京曾杰钟雷吴健 Department of Materials Science Fudan University Department of Information Science and Electronic Engineering Zhejiang University

Developing an electrostatic discharge（ESD） protection device with a better latch-up immunity has been a challenging issue for the nanometer complementary metal-oxide semiconductor（CMOS） technology. In this work, an improved grounded-gate N-channel metal-oxide semiconductor（GGNMOS） transistor triggered silicon-controlled rectifier（SCR）structure, named GGSCR, is proposed for high holding voltage ESD protection applications. The GGSCR demonstrates a double snapback behavior as a result of progressive trigger-on of the GGNMOS and SCR. The double snapback makes the holding voltage increase from 3.43 V to 6.25 V as compared with the conventional low-voltage SCR. The TCAD simulations are carried out to verify the modes of operation of the device.

关键词： electrostatic discharge holding voltage GGSCR