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THE MAKING OF REGIONAL DIAGRAMS IN OMEI-SHAN

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地理学报 1940年 142-146页

作者： SHU-TANG lee,M.sc National Central University National Central University Cantab Cantab

The author made a short visit to the Omei-shan during the summer 1940in the company of a group of his fourteen students in an excursion organgizedby the Geographical Department of the National Central University, Chun... 详细信息

关键词： In THE MAKING OF REGIONAL DIAGRAMS IN OMEI-SHAN than

计算机和专家对糖尿病性视网膜病变早期视网膜病损诊断的比较

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美国医学会眼科杂志（中文版） 2001年第4期13卷 212-217,225页

作者： lee sc lee ET From the school of Electrical and Computer Engineering University of Oklahoma Norman ( Dr S. Lee ) the College of Public Health ( Drs E. lee and Wang and Ms Russell) and the Dean McGee Eye Institute and Department of Ophthalmology ( Drs Kingsley and Wa

目的：使用彩色眼底照片来调查计算机系统和专家间在检出早期的糖尿病性视网膜病损时是否具有可比性。方法：开发了一种计算机系统，通过使用图像处理过程和图形识别技术以发现早期糖尿病性视网膜病损（出血和微动脉瘤，硬质渗出，棉毛... 详细信息

目的：使用彩色眼底照片来调查计算机系统和专家间在检出早期的糖尿病性视网膜病损时是否具有可比性。方法：开发了一种计算机系统，通过使用图像处理过程和图形识别技术以发现早期糖尿病性视网膜病损（出血和微动脉瘤，硬质渗出，棉毛斑）。用获自于奥克拉荷马州的美国印第安人的彩色眼底照片来开发和测试系统。使用3种诊断分类，利用一组369幅彩色眼底幻灯片对计算机系统进行训练，分类包括：病损存在，有问题，或无病损（Y／Q／N），用另外一组不同的428幅幻灯片对该系统进行检测和评估。将其诊断结果与2位专家－Wisconsin大学眼底照相读片中心（Madison) 的分级者和普通眼科医生间的诊断结果进行比较。试验包括用3种（Y／Q／N）和2种诊断分类（Y／N）（有问题的在后者中排除）进行比较。结果：在训练阶段，视网膜专家和计算机系统检出3种病损的一致率，灵敏度和特异性均超过90％，K统计率较高（0．75－0．97），表明在专家和计算机系统间有较好的一致性。在测试阶段。计算机系统和专家间的结果与训练阶段是一致的，具有可比性。结论：在早期视网膜病损的诊断中，计算机视觉系统的表现与专家具有可比性，然而，这是一种自动化的，电子学上容易达到的，非侵入性的计算机系统，糖尿病性视网膜病变早期病损的诊断中可成为一种群众中的筛查工具和临床助手。

关键词：糖尿病性视网膜病变早期诊断视网膜损伤计算机专家

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甘草黄酮类化合物对酪氨酸酶单酚酶的抑制

天然产物研究与开发 2005年第4期17卷 391-395页

作者：傅博强李欢王小如 lee Frank sc 厦门大学化学化工学院化学系现代分析科学教育部重点实验室厦门361005 国家海洋局第一研究所环境与生命过程中物质迁移与反应机理研究室

研究了甘草中四种黄酮类化合物甘草甙、异甘草素葡萄糖芹菜甙、异甘草甙和甘草查耳酮甲对酪氨酸酶单酚酶活性的抑制。结果表明异甘草素葡萄糖芹菜甙、异甘草甙和甘草查耳酮甲的IC50分别为0.072mM,0.038mM,0.0258mM,它们都属于竞争性抑制... 详细信息

研究了甘草中四种黄酮类化合物甘草甙、异甘草素葡萄糖芹菜甙、异甘草甙和甘草查耳酮甲对酪氨酸酶单酚酶活性的抑制。结果表明异甘草素葡萄糖芹菜甙、异甘草甙和甘草查耳酮甲的IC50分别为0.072mM,0.038mM,0.0258mM,它们都属于竞争性抑制剂,甘草甙没有抑制活性。研究表明,异甘草素葡萄糖芹菜甙、异甘草甙和甘草查耳酮甲可以作为潜在的美白化妆品添加剂。

关键词：甘草黄酮酪氨酸酶抑制

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新加坡一所教学医院对肺栓塞病人的回顾

中华结核和呼吸杂志 1997年第Z1期 111页

作者： lee sc Stebbings AEL Tan L Tan WC 孙越(译) DepartmentofMedicine NationalUniversityHospital Singapore

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新加坡一所教学医院对肺栓塞病人的回顾

中华结核和呼吸杂志 1997年第ZK期20卷 111-111页

作者： lee sc Stebbings AEL Tan L Tan WC 孙越(译) DepartmentofMedicine NationalUniversityHospitalSingapore

Stochastic Computing Convolutional Neural Network Architecture Reinvented for Highly Efficient Artificial Intelligence Workload on Field-Programmable Gate Array

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Research 2024年第2期2024卷 55-79页

作者： Yang Yang lee Zaini Abdul Halim Mohd Nadhir Ab Wahab Tarik Adnan Almohamad school of Electrical and Electronic Engineering Universiti Sains MalaysiaNibong Tebal 14300 Penang Malaysia school of Computer sciences Universiti Sains MalaysiaGelugor11800 PenangMalaysia Electrical-Electronics Engineering Department Faculty of EngineeringKarabuk University78050 KarabukTurkiye

Stochastic computing(sc)has a substantial amount of study on application-specific integrated circuit(ASIC)design for artificial intelligence(AI)edge computing,especially the convolutional neural network(CNN)***,sc has little to no optimization on field-programmable gate array(FPGA).scaling up the ASIC logic without FPGA-oriented designs is inefficient,while aggregating thousands of bitstreams is still challenging in the conventional *** research has reinvented several FPGA-efficient 8-bit sc CNN computing architectures,i.e.,sc multiplexer multiply-accumulate,multiply-accumulate function generator,and binary rectified linear unit,and successfully scaled and implemented a fully parallel CNN model on Kintex7 *** proposed sc hardware only compromises 0.14%accuracy compared to binary computing on the handwriting Modified National Institute of Standards and Technology classification task and achieved at least 99.72%energy saving per image feedforward and 31?more data throughput than modern *** to sc,early decision termination pushed the performance baseline exponentially with minimum accuracy loss,making sc CNN extremely lucrative for AI edge computing but limited to classification *** sc's inherent noise heavily penalizes CNN regression performance,rendering sc unsuitable for regression tasks.

关键词： hardware Highly rendering

Glucose-mediated mitochondrial reprogramming by cholesterol export at TM4SF5-enriched mitochondria-lysosome contact sites

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Cancer Communications 2024年第1期44卷 47-75页

作者： Ji Eon Kim So-Young Park Chulhwan Kwak Yoonji lee Dae-Geun Song Jae Woo Jung Haesong lee Eun-Ae Shin Yangie Pinanga Kyung-hee Pyo Eun Hae lee Wonsik Kim Soyeon Kim Chang-Duck Jun Jeanho Yun Sun Choi Hyun-Woo Rhee Kwang-Hyeon Liu Jung Weon lee Department of Pharmacy College of PharmacySeoul National UniversitySeoulRepublic of Korea Research Institute of Pharmaceutical sciences College of PharmacySeoul National UniversitySeoulRepublic of Korea BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit College of Pharmacy and Research Institute of Pharmaceutical SciencesKyungpook National UniversityDaeguRepublic of Korea Department of Chemistry Seoul National UniversitySeoulRepublic of Korea College of Pharmacy Chung-Ang UniversitySeoulRepublic of Korea Natural Product Informatics Research Center Korea Institute of Science and Technology(KIST)Gangneung-siGangwon-doRepublic of Korea school of Life sciences Gwangju Institute of Science and Technology(GIST)GwangjuRepublic of Korea Department of Biochemistry College of MedicineDong-A UniversityBusanRepublic of Korea Global AI Drug Discovery Center College of Pharmacy and Graduate School of Pharmaceutical SciencesEwha Womans UniversitySeoulRepublic of Korea Interdisciplinary Program in Genetic Engineering Seoul National UniversitySeoulRepublic of Korea

Background:Transmembrane 4 L six family member 5(TM4SF5)translocates subcellularly and functions metabolically,although it is unclear how intracellu-lar TM4SF5 translocation is linked to metabolic *** is thus of interests to understand how the traffic dynamics of TM4SF5 to subcellular endosomal membranes are correlated to regulatory roles of ***:Here,we explored the metabolic significance of TM4SF5 localization at mitochondria-lysosome contact sites(MLCSs),using in vitro cells and in vivo animal systems,via approaches by immunofluorescence,proximity labelling based proteomics analysis,organelle reconstitution ***:Upon extracellular glucose repletion following depletion,TM4SF5 became enriched at MLCSs via an interaction between mitochondrial FK506-binding protein 8(FKBP8)and lysosomal *** labeling showed molecular clustering of phospho-dynamic-related protein I(DRP1)and certain mitophagy receptors at TM4SF5-enriched MLCSs,leading to mitochondrial fis-sion and ***4SF5 bound NPC intracellular cholesterol transporter 1(NPC1)and free cholesterol,and mediated export of lysosomal cholesterol to mitochondria,leading to impaired oxidative phosphorylation but intact tri-carboxylic acid(TCA)cycle andβ-*** mouse models,hepatocyte Tm4sf5 promoted mitophagy and cholesterol transport to mitochondria,both with positive relations to liver ***:Our findings suggested that TM4SF5-enriched MLCSs regu-late glucose catabolism by facilitating cholesterol export for mitochondrial reprogramming,presumably while hepatocellular carcinogenesis,recapitulating aspects for hepatocellular carcinoma metabolism with mitochondrial repro-gramming to support biomolecule synthesis in addition to glycolytic energetics.

关键词： cholesterol fluorescent imaging glucose catabolism hepatocellular carcinogenesis mem-brane contact sites mitochondria function mitophagy oxidative phosphorylation protein-protein interaction tetraspanin

Surface-modified Ag@Ru-P25 for photocatalytic CO_(2) conversion with high selectivity over CH_(4) formation at the solid–gas interface

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Carbon Energy 2024年第1期6卷 182-196页

作者： Chaitanya B.Hiragond Sohag Biswas Niket SPowar Junho lee Eunhee Gong Hwapyong Kim Hong Soo Kim Jin-Woo Jung Chang-Hee Cho Bryan M.Wong Su-Il In Department of Energy science&Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Chemical&Environmental Engineering Materials Science&Engineering ProgramDepartment of ChemistryDepartment of Physics&AstronomyUniversity of California-RiversideRiversideCaliforniaUSA Department of Physics and Chemistry Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Nicescience Corporation DaeguRepublic of Korea

Systematic optimization of the photocatalyst and investigation of the role of each component is important to maximizing catalytic activity and comprehending the photocatalytic conversion of CO_(2) reduction to solar fuels.A surface-modified Ag@Ru-P25 photocatalyst with H_(2)O_(2) treatment was designed in this study to convert CO_(2) and H_(2)O vapor into highly selective *** doping followed by Ag nanoparticles(NPs)cocatalyst deposition on P25(TiO_(2))enhances visible light absorption and charge separation,whereas H_(2)O_(2) treatment modifies the surface of the photocatalyst with hydroxyl(–OH)groups and promotes CO_(2) ***-resonance transmission electron microscopy,X-ray photoelectron spectroscopy,X-ray absorption near-edge structure,and extended X-ray absorption fine structure techniques were used to analyze the surface and chemical composition of the photocatalyst,while thermogravimetric analysis,CO_(2) adsorption isotherm,and temperature programmed desorption study were performed to examine the significance of H_(2)O_(2) treatment in increasing CO_(2) reduction *** optimized Ag1.0@Ru1.0-P25 photocatalyst performed excellent CO_(2) reduction activity into CO,CH4,and C2H6 with a~95%selectivity of CH4,where the activity was~135 times higher than that of pristine TiO_(2)(P25).For the first time,this work explored the effect of H_(2)O_(2) treatment on the photocatalyst that dramatically increases CO_(2) reduction activity.

关键词： gas-phase CO_(2) reduction H_(2)O_(2) treatment plasmonic nanoparticles solar fuel photocatalyst surface modification

Effect of self-modeling and self-controlled feedback on the performance of professional swimmers and waterpolo players

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Sports Medicine and Health science 2024年第2期6卷 167-172页

作者： Masoud Mirmoezzi Mansour Sayyah Morteza Taheri Khadijeh Irandoust Mandana Sangari Fatemeh Mirakhori Ali Seghatoleslami lee Hill Katja Weiss Beat Knechtle Amine Ghram Faculty of Physical Education and Sport science Islamic Azad UniversityTehranIran Kashan University of Medical sciences KashanIran Department of Behavioral and Cognitive saciences in Sport University of TehranTehranIran Islamic Azad University Chalous BranchMazandaranIran University of Birjand BirjandIran Division of Gastroenterology&Nutrition Department of PediatricsMcMaster UniversityHamiltonCanada Medbase St.Gallen Am Vadianplatz St.GallenSwitzerland Institute of Primary Care University of ZurichZurichSwitzerland Cardiac Rehabilitation Department Heart HospitalHamad Medical CorporationDohaQatar Healthy Living for Pandemic Event Protection(HL-PIVOT)Network ChicagoIllUSA Department of Sport sciences Imam Khomeini International UniversityQazvinIran

Self-modeling(SM)and self-control(sc)feedback can be presented as two solutions for learning ***,the aim of the present study was to investigate the effects of SM and sc feedback on 100-m freestyle performance of professional swimmers and waterpolo players.25 elite male swimmers and waterpolo players,were randomly assigned to four groups:swimmer group with SM,swimmer group with SM and sc feedback,waterpolo players group with SM,and waterpolo players group with SM and sc feedback.100-m freestyle times and performance were *** and sc feedback for the participants were utilized at the acquisition *** device used included a Lenovo B570 laptop and an Exilim ZR200 canon *** and sc feedback presented to the swimmers and waterpolo players led to improved speed and results,and the effect of presenting SM with sc feedback to swimmers had better *** conclusion,the present study indicates that sc modeling of watching video is a suitable method for professional *** polo trainers can also use SM and sc feedback to enhance their players'swimming technique.

关键词： Feedback Self-control Self-modeling Swimming Water polo