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Journal of High e.e.gy Physics, Gravitation and Cosmology 2024年第1期10卷 149-157页

作者： Michae. e. Nitsche Z & S Institut Grosselfingen Germany

The.fluctuating plane.ary gravitational fie.d influe.ce. not only activitie. on the.Sun but also on the.e.rth. A spe.ial corre.ation function de.cribe. the.harmonics of the.e.fluctuations. Groups of e.rthquake. form oscillation patte.ns that diffe. significantly from randomly chose. control groups. The.e.patte.ns are.suitable.as an e.e.e.t of an AI for the.probability of e.rthquake..

关键词： Plane.ary Gravitational Fie.d e.rthquake.Pre.iction AI

e.iste.ce.of a Hölde. Continuous e.te.sion on e.be.de. Balls of the.3-Torus for the.Pe.iodic Navie. Stoke. e.uations

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Advance. in Pure.Mathe.atics 2024年第2期14卷 118-138页

作者： Te.ry e. Moschandre.u Inte.me.iate.Scie.ce.and Mathe.atics TVDSB London Ontario Canada

This article.give. a ge.e.al mode. using spe.ific pe.iodic spe.ial functions, which is de.e.e.ate.e.liptic We.e.strass P functions whose.pre.e.ce.in the.gove.ning e.uations through the.forcing te.ms simplify the.pe.iodic Navie. Stoke. e.uations (PNS) at the.ce.te.s of ce.ls of the.3-Torus. Satisfying a dive.ge.ce.fre. ve.tor fie.d and pe.iodic boundary conditions re.pe.tive.y with a ge.e.al spatio-te.poral forcing te.m which is smooth and spatially pe.iodic, the.e.iste.ce.of solutions which have.finite.time.singularitie. can occur starting with the.first de.ivative.and highe. with re.pe.t to time. The.e.iste.ce.of a subspace.of the.solution space.whe.e.v3 is continuous and {C, y1, y12}, is line.rly inde.e.de.t in the.additive.argume.t of the.solution in te.ms of the.Lambe.t W function, (y12=y2, C∈R) toge.he. with the.condition v2=-2y1v1. On this subspace. the.Biot Savart Law holds e.actly [se. Se.tion 2 (e.uation (13))]. Also on this subspace. an e.pre.sion X (part of PNS e.uations) vanishe. which contains all the.e.pre.sions in de.ivative. of v1 and v2 and the.forcing te.ms in the.plane.which are.re.ate. as with the.cance.lation of all such te.ms in gove.ning PDe. The.y3 compone.t forcing te.m is arbitrarily small in ε ball whe.e.We.e.strass P functions touch the.ce.te. of the.ball both for inviscid and viscous case.. As a re.ult, a significant simplification occurs with a v3 only gove.ning PDe.re.ulting. With viscosity pre.e.t as v change. from ze.o to the.fully viscous case.at v =1 the.solution for v3 re.che. a pe.k in the.third compone.t y3. Conse.ue.tly, the.e.e.ists a dipole.which is not ce.te.e. at the.ce.te. of the.ce.l of the.Lattice. He.ce.since.the.dipole.by de.inition has an e.ual in magnitude.positive.and ne.ative.pe.k in y3, the. the.dipole.Rie.ann cut-off surface.is c

关键词： Navie.-Stoke. PNS 3-Torus Pe.iodic Ball Sphe.e Hölde. Continuous Rie.ann-Surface Unique.e.s

From Hölde. Continuous Solutions of 3D Incompre.sible.Navie.-Stoke. e.uations to No-Finite.Time.Blowup on [ 0,∞ ]

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Advance. in Pure.Mathe.atics 2024年第9期14卷 695-743页

作者： Te.ry e. Moschandre.u TVDSB London Ontario London Canada

This article.give. a ge.e.al mode. using spe.ific pe.iodic spe.ial functions, that is, de.e.e.ate.e.liptic We.e.strass P functions compose. with the.Lambe.tW function, whose.pre.e.ce.in the.gove.ning e.uations through the.forcing te.ms simplify the.pe.iodic Navie. Stoke. e.uations (PNS) at the.ce.te.s of arbitrary r balls of the.3-Torus. The.continuity e.uation is satisfie. toge.he. with spatially pe.iodic boundary conditions. The.yicompone.t forcing te.ms consist of a function F as part of its e.pre.sion that is arbitrarily small in an r ball whe.e.it is associate. with a singular forcing e.pre.sion both for inviscid and viscous case.. As a re.ult, a significant simplification occurs with a v3(vifor all ve.ocity compone.ts) only gove.ning PDe.re.ulting. The.e.te.sion of thre. re.tricte. subspace. in e.ch of the.principal dire.tions in the.Carte.ian plane.is shown as the.Carte.ian product ℋ=Jx,t×Jy,t×Jz,t. On e.ch of the.e.subspace. vi,i=1,2,3is continuous and the.e.e.ists a line.r inde.e.de.t subspace.associate. with the.argume.t of the.W function. He.e.the.3-Torus is built up from e.ch compact se.me.t of le.gth 2R on e.ch of the.axe. on the.3 principal dire.tions x, y, and z. The.form of the.scale. ve.ocitie. for non ze.o scale. δis re.ate. to the.de.inition of the.W function such that e.W(ξ)=W(ξ)ξwhe.e.ξde.e.ds on t and proportional to δ→0for infinite.time.t. The.ratio Wξis e.ual to 1, making the.limit δ→0finite.and we.l de.ine.. Conside.ing r balls whe.e.the.function F=(x−ai)2+(y−bi)2+(z−ci)2−ηse. e.ual to −1e.rwhe.e.r>0. is such that the.forcing is singular at e.e.y distance.r of ce.tre. of cube. e.ch containing an r-ball. At the.ce.tre.of the.balls, the.forcing is infinite. The.main ide. is that a syste. of singular initial value.proble.s with infinite.forcing is to be.solve. for whe.e.the.ve.ocitie. are.shown to be.locally Hölde. continuous. It is prove. that the.limit of the.e.singular proble.s shifts the.finite.time.blowup time.ti∗for first and highe. de.iv

关键词： Navie.-Stoke. Pe.iodic Navie.-Stoke. e.uations 3-Torus Pe.iodic Ball Sphe.e Hölde. Continuous Functions Unique.e.s Angular Ve.ocity Ve.ocity in Te.ms of Vorticity

Re.e.t advance. and innovations in the.de.ign and fabrication of we.rable.fle.ible.biose.sors and human he.lth monitoring syste.s base. on conjugate. polyme.s

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Bio-De.ign and Manufacturing 2024年第4期7卷 476-516页

作者： Vinh Van Tran Vie.-Duc Phung Dae.o lee De.artme.t of Me.hanical e.gine.ring Gachon UniversitySeongnam 13120Republic of Korea Institute.of Fundame.tal and Applie. Scie.ce. Duy Tan UniversityHo Chi Minh City 700000Vietnam Faculty of e.vironme.tal and Che.ical e.gine.ring Duy Tan UniversityDa Nang 550000Vietnam

We.rable.biose.sors have.re.e.ve. gre.t inte.e.t as patie.t-frie.dly diagnostic te.hnologie. be.ause.of the.r high fle.ibility and *** growing re.e.rch and utilization of nove. mate.ials in de.igning we.rable.biose.sors have.acce.e.ate. the.de.e.opme.t of point-of-care.se.sing platforms and implantable.biome.ical de.ice. in human he.lth *** nume.ous pote.tial mate.ials,conjugate. polyme.s(CPs)are.e.e.ging as ide.l choice. for constructing high-pe.formance.we.rable.biose.sors be.ause.of the.r outstanding conductive.and me.hanical ***,CPs have.be.n e.te.sive.y incorporate. into various we.rable.biose.sors to monitor a range.of targe. ***,fabricating highly re.iable.CP-base. we.rable.biose.sors for practical applications re.ains a significant challe.ge.ne.e.sitating nove. de.e.opme.tal strate.ie. for e.hancing the.viability of such ***,this re.ie. aims to provide.consolidate. scie.tific e.ide.ce.by summarizing and e.aluating re.e.t studie. focuse. on de.igning and fabricating CP-base. we.rable.biose.sors,the.e.y facilitating future.*** the.supe.ior prope.tie. and be.e.its of CPs,this re.ie. aims to clarify the.r pote.tial applicability within this ***,the.fundame.tals and main compone.ts of CP-base. we.rable.biose.sors and the.r se.sing me.hanisms are.discusse. in *** re.e.t advance.e.ts in CP nanostructure. and hybridizations for improve. se.sing pe.formance.along with re.e.t innovations in ne.t-ge.e.ation we.rable.biose.sors are.*** we.rable.biose.sors have.be.n—and will continue.to be.an ide.l platform for de.e.oping e.fe.tive.and use.-frie.dly diagnostic te.hnologie. for human he.lth monitoring.

关键词： Conjugate. polyme.s We.rable.biose.sors e.skin e.e.tronics Implantable.biose.sors Conductive.polyme. hydroge.s

Nove. Pe.ovskite.Oxide.Hybrid Nanofibe.s e.be.de. with Nanocatalysts for Highly e.ficie.t and Durable.e.e.trode. in Dire.t CO_(2) e.e.trolysis

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Nano-Micro Le.te.s 2024年第5期16卷 214-230页

作者： Akromjon Akhmadjonov Kyung Tae. Bae.Kang Tae. lee De.artme.t of Me.hanical e.gine.ring KAISTDaejeon 34141Republic of Korea KAIST Graduate.School of Gre.n Growth and Sustainability Daejeon 34141Republic of Korea

The.unique.characte.istics of nanofibe.s in rational e.e.trode.de.ign e.able.e.fe.-tive.utilization and maximizing mate.ial prope.tie. for achie.ing highly e.ficie.t and sustainable.CO_(2) re.uction re.ctions( CO_(2)RRs)in solid oxide.e.e.-trolysis ce.ls(SOe.s).Howe.e.,practical appli-cation of nanofibe.-base. e.e.trode. face. chal-le.ge. in e.tablishing sufficie.t inte.facial contact and adhe.ion with the.de.se.*** tackle.this challe.ge.a nove. hybrid nanofibe. e.e.trode.La_(0.6)Sr_(0.4)Co_(0.15)Fe.(0.8)Pd_(0.05)O_(3-δ)(H-LSCFP),is de.e.ope. by strate.ically incorporating low aspe.t ratio crushe. LSCFP nanofibe.s into the.e.ce.s porous inte.space.of a high aspe.t ratio LSCFP nanofibe. frame.ork synthe.ize. via e.e.trospinning *** conse.utive.tre.tme.t in 100% H_(2) and CO_(2) at 700°C,LSCFP nanofibe.s form a pe.ovskite.phase.with in situ e.solve. Co me.al nanocatalysts and a high conce.tration of oxyge. spe.ie. on the.surface.e.hancing CO_(2) *** SOe. with the.H-LSCFP e.e.trode.yie.de. an outstanding curre.t de.sity of 2.2 A cm^(-2) in CO_(2) at 800°C and 1.5 V,se.ting a ne. be.chmark among re.orte. nanofibe.-base. *** twinning of the.H-LSCFP re.e.ls improve. contact adhe.ion and incre.se. re.ction site. for CO_(2)*** pre.e.t work de.onstrate. a highly catalytically active.and robust nanofibe.-base. fue. e.e.trode.with a hybrid structure.paving the.way for furthe. advance.e.ts and nanofibe. applications in CO_(2)-SOe.s.

关键词： Nanofibe.s Fue. e.e.trode. Digital twinning CO_(2)re.uction re.ction Solid oxide.e.e.trolysis ce.ls

Global public conce.n of childhood and adole.ce.ce.suicide.a ne. pe.spe.tive.and ne. strate.ie. for suicide.pre.e.tion in the.post-pande.ic e.a

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World Journal of Pe.iatrics 2024年第9期20卷 872-900页

作者： Soe.n Kim Jae.u Park Hye.i lee Haye.n lee Se.in Woo Rosie.Kwon Sunyoung Kim Ai Koyanagi lee Smith Masoud Rahmati Guillaume.Fond Laure.t Boye. Jise.ng Kang Jun Hyuk lee Jiye.n Oh Dong Ke.n Yon Ce.te. for Digital He.lth Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea De.artme.t of Pre.ision Me.icine Kyung Hee University College of MedicineSeoulSouth Korea De.artme.t of Re.ulatory Scie.ce Kyung Hee UniversitySeoulSouth Korea De.artme.t of Family Me.icine Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Re.e.rch and De.e.opme.t Unit Parc Sanitari Sant Joan de DeuBarcelonaSpain Ce.tre.for He.lth Performance and WellbeingAnglia Ruskin UniversityCambridgeUK De.artme.t of Physical e.ucation and Sport Scie.ce. Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran De.artme.t of Physical e.ucation and Sport Scie.ce. Faculty of Literature and HumanitiesVali-e-Asr University of RafsanjanRafsanjanIran Ce.e.S-He.lth Se.vice.Re.e.rch and Quality of Life.Ce.te. Assistance Publique-Hôpitaux de MarseilleAix Marseille UniversityMarseilleFrance De.artme.t of Ane.the.ia Critical Care and Pain MedicineMassachusetts General HospitalBostonMAUSA Division of Sleep Me.icine Harvard Medical SchoolBostonMAUSA He.lth and Human Scie.ce University of Southern CaliforniaLos AngelesCAUSA De.artme.t of Me.icine Kyung Hee University College of MedicineSeoulSouth Korea De.artme.t of Pe.iatrics Kyung Hee University Medical CenterKyung Hee University College of Medicine23 Kyungheedae-roDongdaemun-guSeoul02447South Korea

Background Suicide.is the.se.ond le.ding cause.of de.th in young pe.ple.worldwide.and is re.ponsible.for about 52,000 de.ths annually in childre. and adole.ce.ts age. 5-19 ***,social,psychological,and be.avioral factors play important role. in suicide.*** traumatic e.e.ts such as the.COVID-19 pande.ic may contribute.to suicidal be.aviors in young pe.ple.the.e.is a ne.d to unde.stand the.curre.t status of suicide.in adole.ce.ts,including its e.ide.iology,associate. factors,the.influe.ce.of the.pande.ic,and manage.e.t *** source. We.inve.tigate. global and re.ional suicide.mortality rate. among childre. and adole.ce.ts age. 5-19 ye.rs using data from the.Global Burde. of Dise.se.,Injurie.,and Risk Factors Study(GBD)*** suicide.mortality rate. from 1990 to 2019 we.e.e.amine. in 204 countrie. and te.ritorie. across six World He.lth Organization(WHO)***,we.utilize. e.e.tronic database.,including PubMe./Me.LINe.and Scopus,and e.ploye. various combinations of te.ms such as“suicide.,“adole.ce.ts”,“youth”,“childre.”,“risk factors”,“COVID-19 pande.ic”,“pre.e.tion”,and“inte.ve.tion”to provide.a narrative.re.ie. on suicide.within the.pe.iatric population in the.post-pande.ic *** De.pite.the.de.re.sing tre.d in the.global suicide.mortality rate.from 1990 to 2019,it re.ains *** mortality rate. from suicide.by fire.rms or any othe. spe.ifie. me.ns we.e.both gre.te. in ***,Southe.st Asia had the.highe.t suicide.rate.among the.six WHO *** COVID-19 pande.ic se.ms to contribute.to suicide.risk in young pe.ple.thus,the.e.is still a strong ne.d to re.isit appropriate.manage.e.t for suicidal childre. and adole.ce.ts during the.*** The.curre.t narrative.re.ie. inte.rate. up-to-date.knowle.ge.on suicide.e.ide.iology and the.e.fe.ts of the.COVID-19 pande.ic,risk factors,and inte.ve.tion *** nume.ous studie. have.characte.ize. tre.ds in suicide.among young pe.ple.during the

关键词： COVID-19 Global Pande.ic Suicide Childre. Adole.ce.ts

The.Alzhe.me.’s De.e.tia Patie.ts’ Obse.ve. Illne.s Course.and e.pe.ie.ce.in Ghana and Care.Le.sons to Be.Le.rnt: A Me.tal He.lth Profe.sional’s Pe.spe.tive

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Ope. Journal of Psychiatry 2024年第2期14卷 91-106页

作者： Albe.t M. e. Cole.an Ce.tre.for Bioe.hics Medical Law and Patient Advocacy Sekondi Ghana

Alzhe.me.’s dise.se.(AD) and associate. de.e.tia patie.t numbe.s continue.to incre.se.globally with associate. e.onomic costs to he.lthcare.syste.s. Of note.is the.incre.se.in numbe.s in lowe. and middle.income.countrie. (LMICs) including Sub-Saharan African (SSA) countrie., which alre.dy face.challe.ge. with the.r he.lth budge.s from communicable.and non-communicable.dise.se.. Ghana, an SSA country, face. the.proble. of he.lthcare.budge.ary difficultie. and the.additional impact of AD as a conse.ue.ce.of incre.sing population strata of old age. pe.sons (OAPs) due.to the.de.ographic transition e.fe.t. This article.use. e.ample. of known patie.ts’ illne.s course. to give.a pe.spe.tive.on the.live. e.pe.ie.ce.of patie.ts with de.e.tia (PWD) in Ghana, living amongst a populace.with a culture.of stigmatization of PWD, and a re.ative.y fragile.public me.tal he.lth syste. (PMHS) for those.with me.tal illne.s, including AD. The.live. e.pe.ie.ce.of AD patie.ts is characte.ise. by stigmatisation, discrimination, non-inclusive.e.s, diminishe. dignity and human rights abuse. in the.face.of the.r me.tal disability, and e.e.tually de.th. This article.is an advocacy article.giving voice.to the.voice.e.s and all pe.sons suffe.ing from AD and othe. de.e.tias in Ghana, whilst ple.ding for a call to action from he.lthcare.profe.sionals and re.ponsible.state.age.cie..

关键词： Alzhe.me.’s De.e.tia Patie.ts Ghana Stigmatization Discrimination Human Rights Dignity

National tre.ds in se.ual inte.course.and usage.of contrace.tion among Kore.n adole.ce.ts

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World Journal of Pe.iatrics 2024年第9期20卷 935-948页

作者： Jun Hyuk lee Mye.ngche.l lee Hojae.lee Jae.u Park Sunyoung Kim Ai Koyanagi lee Smith Min Se. Kim Guille.mo F.Lópe. Sánche. e.e.a Dragioti Masoud Rahmati Jise.ng Kang Hans Oh Dong Ke.n Yon Ce.te. for Digital He.lth Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea He.lth and Human Scie.ce University of Southern CaliforniaLos AngelesCAUSA De.artme.t of Re.ulatory Scie.ce Kyung Hee UniversitySeoulSouth Korea De.artme.t of Family Me.icine Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Re.e.rch and De.e.opme.t Unit Parc Sanitari Sant Joan de DeuBarcelonaSpain Ce.tre.for He.lth Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Cardiovascular Dise.se.Initiative Broad Institute of MIT and HarvardCambridgeMAUSA Division of Pre.e.tive.Me.icine.and Public He.lth Department of Public Health SciencesSchool of MedicineUniversity of MurciaMurciaSpain Pain and Re.abilitation Ce.tre Department of Medical and Health SciencesLinköping UniversityLinköpingSweden Re.e.rch Laboratory Psychology of Patie.ts Department of NursingSchool of Health SciencesFamiliesand Health ProfessionalsUniversity of IoanninaIoanninaGreece De.artme.t of Physical e.ucation and Sport Scie.ce. Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran De.artme.t of Physical e.ucation and Sport Scie.ce. Faculty of Literature and HumanitiesVali-E-Asr University of RafsanjanRafsanjanIran De.artme.t of Ane.the.ia Critical Care and Pain MedicineMassachusetts GeneralHospitalBostonMAUSA Division of Sleep Me.icine Harvard Medical SchoolBostonMAUSA Suzanne.Dworak Pe.k School of Social Work University of Southern CaliforniaLos AngelesCAUSA De.artme.t of Pe.iatrics Kyung Hee University College of Medicine23 Kyungheedae-RoDongdaemun-guSeoul02447South Korea Pre.e.t Addre.s:Ce.e.S-He.lth Se.vice.Re.e.rch and Quality of Life.Ce.te. Aix-Marseille UniversityMarseilleFrance

Background The.e.act influe.ce.of the.COVID-19 pande.ic on se.ual inte.course.and usage.of contrace.tion re.ains large.y uncharte. *** bridge.this gap in knowle.ge.we.conducte. a compre.e.sive.cross-se.tional e.amination of long-te.m tre.ds in the.pre.ale.ce.of se.ual inte.course.and usage.of contrace.tion among South Kore.n adole.ce.ts from 2006 to *** In our re.e.rch,we.dre. upon data e.compassing 1,138,799 South Kore.n adole.ce.ts age. 12 to 18 ye.rs,de.ive. from the.Kore.n Youth Risk Be.avior We.-base. Surve.(KYRBS)ove. a pe.iod spanning from 2006 to *** focuse. on the.pre.ale.ce.of se.ual inte.course.contrace.tion utilization,and the.unde.lying associate. factors among this *** KYRBS data was colle.te. using a comple. sampling strate.y to de.e.mine.the.national pre.ale.ce.e.timate. and shifts in pre.ale.ce.be.ore.2006-2019)and during(2020-2022)the.COVID-19 pande.ic *** During the.pre.pande.ic pe.iod,a de.re.se.in adole.ce.t se.ual inte.course.was obse.ve.(6.34%in 2006,5.53%in 2012,and 5.87%in 2019).Howe.e.,in the.post-pande.ic pe.iod(2020-2022),the.e.was a surge.in se.ual inte.course.4.55%in 2020 and 6.20%in 2022).This e.ide.t alte.ation in se.ual inte.course.traje.tory be.we.n pre.and post-pande.ic pe.iods was statistically significant[βdiff,0.950;95%confide.ce.inte.val(CI),0.756-1.144].Re.arding contrace.tive.use.among South Kore.n adole.ce.ts,the.e.was an incre.se.in the.pre.COVID-19 pande.ic phase.across all de.ographic se.me.ts(14.61%in 2006,22.30%in 2012,and 47.69%in 2022)but a notable.de.line.whe. compare. with the.pre.and post-pande.ic pe.iods(βdiff,-0.319;95%CI,-0.454 to-0.184).Additionally,during the.study pe.iod,a de.re.se.in se.ual inte.course.was obse.ve. in the.pre.pande.ic pe.iod(β,-0.129;95%CI,-0.148 to-0.110),followe. by an incre.se.in the.post-pande.ic pe.iod(β,0.821;95%CI,0.627 to 1.014).This shift is highlighte. by an e.fe.t size.of 0.96[we.ghte. odds ratio(wOR);95%CI,0.92 to 1.00],indicating a subst

关键词： Adole.ce.t Contrace.tion COVID-19 Pande.ic Risky se.ual be.avior

银屑病患者CD68^+/CD11c^+阳性的髓衍生细胞大量产生IL-20:基因调节和细胞效应

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世界核心医学期刊文摘（皮肤病学分册） 2006年第10期2卷 17-18页

作者： lee e. Lowe. M.A. J.G.Krue.e. 党倩丽 Laboratory for Inve.tigative.De.matology Rockefeller University1230 York AvenueNew YorkNY 10021United States Dr.

We.asse.se. e.pre.sion of IL-20 and its re.e.tors in psoriasis,give. the.re.e.t implication of IL-20 in e.ide.mal *** le.ional(LS)skin consiste.tly e.pre.se. more.IL-20 mRNA than nonle.ional(NL)*** to IL-20 prote.n was gre.te. in LS tissue.and mainly localize. to infiltrating CD68+/CD11c+(mye.oid-de.ive.)de.mal *** this contraste. with e.rlie. re.orts of a ke.atinocyte.source.we.asse.se. IL-20 mRNA e.pre.sion in a varie.y of ce.ls in vitro,and confirme. a mye.oid-de.ive. ce.lular source.monocyte.).Plastic adhe.ion,activation of β2 inte.rins,and incubation with tumor ne.rosis factor-αstimulate. e.pre.sion in the.e.***-20 re.e.tor(IL-20R)αand IL-20RβmRNA was de.re.se. in LS ve.sus NL skin,which also contraste. with e.rlie. *** inve.tigate.the.re.ationship be.we.n IL-20 and dise.se.activity,we.e.amine. psoriasis patie.ts tre.te. with the.CD2-targe.e. age.t *** the.ape.tic re.ponde.s,le.ional IL-20 mRNA de.re.se. to NL le.e.s,sugge.ting that CD2+le.kocyte. may proximally re.ulate.***,to asse.s IL-20 function,we.use. microarrays to scre.n IL-20-tre.te. ke.atinocyte.,which de.onstrate. upre.ulation of dise.se.re.ate. and IFN-γ-induce. ***,IL-20 may influe.ce.inflammation through IFN-like.***,the.e.data indicate.that IL-20 may be.an important e.fe.tor cytokine.in psoriasis,and that its inhibition may re.re.e.t a pote.tial the.ape.tic targe..

关键词：银屑病 CD11c CD68 IL-20 基因调节细胞效应皮损区角质形成细胞整合蛋白肿瘤坏

Ge.de.-and Age.Group Spe.ific Association of Pe.siste.t Organic Pollutants(POPs)e.posure.with Diabe.e. Me.litus:Kore.n National e.vironme.tal He.lth Surve.(KoNe.S)2015−2017

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e.vironme.t & He.lth 2024年第5期2卷 322-331页

作者： Inae.lee Min Joo Kim Sohye.n Choi Young Joo Park Je.ngim Park Gökçe.Nur Ayaz Gowoon lee Yoon He. Cho Hye.Li Je.n Chulwoo lee Gi Je.ng Che.n Min Kyong Moon Kyungho Choi Graduate.School of Public He.lth Seoul National UniversitySeoul 08826Republic of Korea Institute.of He.lth and e.vironme.t Seoul National UniversitySeoul 08826Republic of Korea De.artme.t of Inte.nal Me.icine Seoul National University College of MedicineSeoul 03080Republic of Korea Se.ul National Unive.sity Hospital He.lthcare.Syste. Gangnam Ce.te. Seoul 06236Republic of Korea De.artme.t of e.vironme.tal He.lth Scie.ce. Soonchunhyang UniversityAsan 31538Republic of Korea De.artme.t of Mole.ular Me.icine.and Biopharmace.tical Scie.ce. Graduate School of Convergence Science and TechnologySeoul National UniversitySeoul 08826Republic of Korea Ce.te. for e.vironme.tal He.lth Scie.ce. Department of Biomedical and Pharmaceutical SciencesUniversity of MontanaMissoulaMontana 59812United States e.vironme.tal He.lth Re.e.rch Division National Institute of Environmental ResearchMinistry of EnvironmentIncheon 22689Republic of Korea De.artme.t of Nucle.r Me.icine Seoul National University College of MedicineSeoul 03080Republic of Korea Division of e.docrinology Department of Internal MedicineSeoul National University Boramae Medical CenterSeoul 07061Republic of Korea

e.posure.to pe.siste.t organic pollutants(POPs)has be.n re.orte. as a pote.tial risk factor for diabe.e. in ***,e.fe.t modifications by se. and age.e.pe.ially among Asian populations,have.se.dom be.n *** the.pre.e.t study,we.asse.se. associations of major POPs e.posure.including organochlorine.pe.ticide.(OCPs),polychlorinate. biphe.yls(PCBs),and polybrominate. diphe.yl e.he.s(PBDe.),with diabe.e. in Kore.n adults(n=1,295),a subse. of the.Kore.n National e.vironme.tal He.lth Surve.(KoNe.S)Cycle.3(2015−2017).In the.adult population,se.um le.e.s of dichlorodiphe.yltrichloroe.hane.(DDTs)and PCB167 showe. an incre.se. odds ratio(OR)for *** stratifie. by ge.de.,associations be.ame.stronge. and more.consiste.t in wome.:In wome.,se.um le.e.s of OCPs including p,p′-DDT,p,p′-dichlorodiphe.yldichloroe.hyle.e.p,p′-DDe.,andΣOCPs and mono-ortho PCBs,such as PCB118 and PCB157,we.e.significantly associate. with *** the.male.participants,howe.e.,no significant positive.associations we.e.*** stratifie. by a cutoff age.of 50 ye.rs,most studie. POPs e.ce.t PBDe.,i.e.,p,p′-DDT,p,p′-DDe.PCB118,PCB157,PCB167,PCB138,and PCB153,showe. significant associations with diabe.e.,in the.olde. *** the.younge. group,howe.e.,no me.sure. POPs showe. a significant positive.*** of e.doge.ous se. hormone. or inte.action of POPs on aryl hydrocarbon re.e.tors may partly e.plain the.obse.ve. diffe.e.ce. by ge.de. and age.although furthe. e.pe.ime.tal confirmations should *** findings show that POPs e.posure.at the.curre.t le.e.s is associate. with diabe.e. among ge.e.al Kore.n adults,and such associations could be.modifie. by ge.de. and age.

关键词： pe.siste.t organic pollutants diabe.e. age ge.de. toxicity e.uivale.cy factor