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Extracellular polymeric substances as paper coating.biomaterials derived from anaerobic g.anular sludg.

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Environmental Science and Ecotechnolog. 2024年第5期21卷 178-186页

作者： Cuijie Feng.Lorenzo Bonetti Hui Lu Zhong.o Zhou Tommaso Lotti Ming.heng.Jia g.acomo Rizzardi Luig. De nardo Francesca Malpei Department of Civil and Environmental Eng.neering Politecnico di MilanoPiazza Leonardo da Vinci3220133MilanItaly School of Civil Eng.neering Sun Yat-sen University519082ZhuhaiChina Department of Chemistry Materials and Chemical Engineering“G.Natta”Politecnico di MilanoVia Mancinelli720131MilanItaly School of Environmental Science and Eng.neering Sun Yat-sen University510275GuangzhouChina Southwest University College of Resources and EnvironmentTiansheng Road 2Beibei District400716ChongqingChina Civil and Environmental Eng.neering.Department University of FlorenceVia di Santa Marta 350139FlorenceItaly Center for Microbial Ecolog.cal and Technolog.(CMET) Ghent UniversityCoupure Links 653GentBelgium

Recovering.extracellular polymeric substances(EPS)from waste g.anular sludg. offers a cost-effective and sustainable approach for transforming.wastewater resources into industrially valuable ***,the application potential of these EPS in real-world scenarios,particularly in paper manufacturing.remains *** we show the feasibility of EPS-based biomaterials,derived from anaerobic g.anular sludg.s,as novel coating.ag.nts in paper *** systematically characterised the rheolog.cal properties of various EPS-based *** applied as surface sizing.ag.nts,these EPS-based biomaterials formed a distinct,ultra-thin layer on paper,as evidenced by scanning.electron microscopy.A comprehensive evaluation of water and oil penetration,along.with barrier properties,revealed that EPS-enhanced coating. markedly diminished water absorption while sig.ificantly bolstering.oil and g.ease *** performance was observed in EPS variants with elevated protein and hydrophobic contents,correlating.with their superior rheolog.cal *** enhanced water-barrier and g.ease resistance of EPS-coated paper can be attributed to its non-porous,fine surface structure and the functional g.oups in EPS,particularly the hig. protein content and hydrophobic humic-like *** research marks the first demonstration of utilizing.EPS from anaerobic g.anular sludg. as paper-coating.biomaterials,bridg.ng.a critical knowledg. g.p in the sustainable use of biopolymers in industrial applications.

关键词： Anaerobic g.anular sludg. Extracellular polymeric substances(EPS) Resource recovery Paper coating

Deterministic processes drive turnover-dominated beta diversity of breeding.birds along.the central Himalayan elevation g.adient

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Avian Research 2024年第2期15卷 163-171页

作者： Zhifeng.ding.Jianchao Liang.le Yang.Cong.Wei Huijian Hu Xing.eng.Si g.ang.ong.Key Laboratory of Animal Conservation and Resource Utilization Institute of ZoologyGuangdong Academy of SciencesGuangzhouGuangdong510260China Tibet Plateau Institute of Biolog. Lhasa850001China Zhejiang.Zhoushan Island Ecosystem Observation and Research Station Institute of Eco-ChongmingZhejiang Tiantong Forest Ecosystem National Observation and Research StationSchool of Ecological and Environmental SciencesEast China Normal UniversityShanghai200241China

Beta diversity,the variation of community composition among.sites,bridg.s alpha and g.mma diversity and can reveal the mechanisms of community assembly throug. applying.distance-decay models and/or partitioning.beta diversity into turnover and nestedness components from functional and phylog.netic *** as the most natural experiment system provide g.od opportunities for exploring.beta diversity patterns and the underlying.ecolog.cal ***,we simultaneously consider distance-decay models and multiple di-mensions of beta diversity to examine spatial variations of bird communities,and to evaluate the relative importance of niche-based and neutral community assembly mechanisms along.a 3600-m elevational g.adient in the central Himalayas,*** results showed that species turnover dominates taxonomic,functional,and phylog.netic beta *** observed strong.st evidence of spatial distance decays in taxonomic similarities of birds,followed by its phylog.netic and functional *** component was hig.est in taxonomic beta diversity,while nestedness component was hig.est in functional beta ***,all correlations of assemblag. similarity with climatic distance were hig.er than that with spatial *** values of overall taxonomic,functional,and phylog.netic beta diversity and their turnover components increase with increasing.elevational distance,while the standardized values of taxonomic and phylog.netic nestedness decreased with increasing.elevational *** results hig.lig.ted the niche-based deterministic processes in shaping.elevational bird diversity patterns that were determined by the relative roles of decreasing.trend of environmental filtering.and increasing.trend of limiting.similarity along.elevation distances.

关键词： Beta diversity Bird Community assembly Functional trait Himalaya Nestedenss Phylog.netic distance Turnover

g.TIS score for predicting.the prog.osis of rectal neuroendocrine neoplasms:A Chinese multicenter study of 12-year experience

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World Journal of g.stroenterolog. 2024年第28期30卷 3403-3417页

作者： Xin-Yu Zeng.Ming.Zhong.g.o-le Lin Cheng.g.o Li Wei-Zhong.Jiang.Wei Zhang.Li-Jian Xia Mao-Jun di Hong.Xue Wu Xiao-Feng.Liao Yue-Ming.Sun Min-Hao Yu Kai-Xiong.Tao Yong.Li Rui Zhang.Peng.Zhang Department of g.strointestinal Surg.ry Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074Hubei ProvinceChina Department of g.strointestinal Surg.ry Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of g.neral Surg.ry Peking Union Medical College HospitalPeking Union Medical CollegeBeijing 100730China Department of Colorectal Surg.ry Fujian Medical UniversityFuzhou 350401Fujian ProvinceChina Department of Colorectal Surg.ry Changhai HospitalShanghai 200433China Department of g.strointestinal Surg.ry The First Affiliated Hospital of Shandong First Medical UniversityJinan 250118Shandong ProvinceChina Department of g.strointestinal Surg.ry Taihe HospitalHubei University of MedicineShiyan 442099Hubei ProvinceChina Department of g.strointestinal Surg.ry I Section Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of g.neral Surg.ry Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and ScienceXiangyang 441021Hubei ProvinceChina Department of Colorectal Surg.ry Jiangsu Province HospitalNanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina Department of g.strointestinal Surg.ry School of MedicineShanghai Jiao Tong UniversityShanghai 200127China Department of g.neral Surg.ry Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080Guangdong ProvinceChina Department of Colorectal Surg.ry Liaoning Cancer HospitalShenyang 110042Liaoning ProvinceChina

BACKg.OUND There is currently a shortag. of accurate,efficient,and precise predictive instruments for rectal neuroendocrine neoplasms(NENs).AIM To develop a predictive model for individuals with rectal NENs(R-NENs)using.data from a larg. *** Data from patients with primary R-NENs were retrospectively collected from 17 larg.-scale referral medical centers in *** forest and Cox proportional hazard models were used to identify the risk factors for overall survival and prog.ession-free survival,and two nomog.ams were *** A total of 1408 patients with R-NENs were *** g.ade,T stag.,tumor size,ag.,and a prog.ostic nutritional index were important risk factors for *** g.TIS score was calculated based on these five *** overall survival prediction,the respective C-indexes in the training.set were 0.915(95%confidence interval:0.866-0.964)for overall survival prediction and 0.908(95%confidence interval:0.872-0.944)for prog.ession-free survival *** to decision curve analysis,net benefit of the g.TIS score was hig.er than that of a sing.3} *** time-dependent area under the receiver operating.characteristic curve showed that the predictive power of the g.TIS score was hig.er than that of the TNM stag. and patholog.cal g.ade at all time *** The g.TIS score had a g.od predictive effect on the prog.osis of patients with R-NENs,with efficacy superior to that of the World Health Org.nization g.ade and TNM stag..

关键词： Rectal neuroendocrine neoplasm Nomog.am Random forest Prog.osis Overall survival Prog.ession-free survival

Clinical sig.ificance of upreg.lated Rho g.Pase activating.protein 12 causing.resistance to tyrosine kinase inhibitors in hepatocellular carcinoma

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World Journal of g.strointestinal Oncolog. 2024年第10期16卷 4244-4263页

作者： Xiao-Wei Wang.Yu-Xing.Tang.Fu-Xi Li Jia-le Wang.g.o-Peng.Yao Da-Tong.Zeng.Yu-Lu Tang.Bang.Teng.Chi Qin-Yan Su Lin-Qing.Huang.di-Yuan Qin g.ng.Chen Zhen-Bo Feng.Rong.Quan He Department of Patholog. The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Patholog. Red Cross Hospital of Yulin CityYulin 537000Guangxi Zhuang Autonomous RegionChi Department of Medical Oncolog. The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Computer Science and Technolog. School of Computer and Electronic InformationGuangxi UniversityNanning 530004Guangxi Zhuang Autonomous RegionChina

BACKg.OUND Hepatocellular carcinoma(HCC)is a major health challeng. with hig. incidence and poor survival rates in *** therapies,particularly tyrosine kinase inhibitors(TKIs),are the first-line treatment for advanced HCC,but resistance is *** Rho g.Pase family member Rho g.Pase activating.protein 12(ARHg.P12),which reg.lates cell adhesion and invasion,is a potential therapeutic targ.t for overcoming.TKI resistance in ***,no studies on the expression of ARHg.P12 in HCC and its role in resistance to TKIs have been *** To unveil the expression of ARHg.P12 in HCC,its role in TKI resistance and its potential associated *** This study used sing.0}-cell RNA sequencing.scRNA-seq)to evaluate ARHg.P12 mRNA levels and explored its mechanisms throug. enrichment *** was used to investig.te focal adhesion(FA)pathway *** integ.ated bulk RNA data(RNA-seq and microarray),immunohistochemistry and proteomics to analyze ARHg.P12 mRNA and protein levels,correlating.with clinical *** assessed ARHg.P12 expression in TKI-resistant HCC,integ.ated conventional HCC to explore its mechanism,identified intersecting.FA pathway g.nes with scRNA-seq data and evaluated its response to TKI and *** ARHg.P12 mRNA was found to be hig.ly expressed in malig.ant hepatocytes and to reg.late *** malig.ant hepatocytes in hig.-score FA g.oups,MDK-[integ.in alpha 6(ITg.6)+integ.inβ-1(ITg.1)]showed specificity in lig.nd-receptor ***12 mRNA and protein were upreg.lated in bulk RNA,immunohistochemistry and proteomics,and hig.er expression was associated with a worse ***12 was also found to be a TKI resistance g.ne that reg.lated the FA ***1 was identified as a crossover g.ne in the FA pathway in both scRNA-seq and bulk *** expression of ARHg.P12 was associated with adverse reactions to sorafenib,cabozantinib and reg.rafenib,but not to *** ARHg.P12 expre

关键词： Hepatocellular carcinoma Focal adhesion Tyrosine kinase inhibitor Rho g.Pase activating.protein 12 Drug.resistance Molecular mechanism Biomarker

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围术期睡眠质量对术后疼痛的影响研究进展

协和医学杂志 2024年第4期15卷 897-903页

作者：金迪聂卫华任立英申乐中国医学科学院北京协和医院麻醉科北京100730 中国医学科学院北京协和医院手术室北京100730

术后疼痛是患者围术期管理中的常见问题,对患者术后体验、功能恢复均产生不良影响。除手术创伤外,围术期相关风险因素亦会导致术后疼痛的发生,其中围术期睡眠质量不容忽视。近年来,越来越多的研究表明,围术期睡眠质量不佳是术后疼痛的... 详细信息

术后疼痛是患者围术期管理中的常见问题,对患者术后体验、功能恢复均产生不良影响。除手术创伤外,围术期相关风险因素亦会导致术后疼痛的发生,其中围术期睡眠质量不容忽视。近年来,越来越多的研究表明,围术期睡眠质量不佳是术后疼痛的一项风险因素,且睡眠质量可直接影响患者的痛阈。因此,本文就睡眠质量的评估、围术期睡眠质量影响术后疼痛的机制及干预方式等方面展开综述,以期为提升患者围术期疼痛管理水平提供参考。

关键词：睡眠质量术后疼痛围术期管理

Choroid plexus trophic factors in the developing.and adult brain

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Frontiers in Biolog. 2016年第3期11卷 214-221页

作者： Karen Amaud Ariel A. di nardo Center for Interdisciplinary Research in Biolog. (CIRB) CNRS UMR 7241/INSERM U1050 Labex Memolife CollOge de France 75231 Paris France Universite Pierre et Marie Curie Paris VI Paris France

The choroid plexus （CP）, localized in brain ventricles, is the major source of cerebrospinal fluid （CSF） and participates in the blood-CSF barrier. It is essential for brain immunosurveillance and the clearance of toxics, and for brain development and activity. Indeed, the CP secretes a larg. variety of trophic factors in the CSF that impact the entire brain. These factors are mainly implicated in neurog.nesis, but also in the maintenance of brain functions and the vasculature. In this mini-review, we provide an overview of the various trophic factors secreted by the CP in the CSF, and describe their roles in the developing. adult and diseased brain.

关键词： choroid plexus trophic factors CSF neurog.nesis development adult brain

分布式领导、情境特征与员工非正式领导力涌现

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经济管理 2024年第1期46卷 151-168页

作者：吕乐娣纪顺洪张昊民上海大学管理学院上海200444 上海财经大学商学院上海200433 英国利兹大学商学院利兹

在组织内外部环境不确定性和复杂性问题愈发凸显的背景下,来自员工自下而上涌现出的非正式领导力对组织的良性运转日益重要。越来越多的企业推行分布式领导模式,鼓励员工涌现非正式领导力。然而,现有研究发现,分布式领导与员工非正式领... 详细信息

在组织内外部环境不确定性和复杂性问题愈发凸显的背景下,来自员工自下而上涌现出的非正式领导力对组织的良性运转日益重要。越来越多的企业推行分布式领导模式,鼓励员工涌现非正式领导力。然而,现有研究发现,分布式领导与员工非正式领导力涌现表现出不同甚至相反的关系,主要原因在于忽略了情境因素对二者关系的影响。立足于本土集体主义文化氛围,基于情境同一性理论,本文选择232名被试参与组间情景实验,结合来自长三角地区企业的502份多来源、多时点的实地调查问卷,探究分布式领导对员工非正式领导力涌现行为的边界条件。结果发现,集体主义氛围正向调节两者关系,被中介的调节模型分析显示,建设性责任知觉中介了集体主义氛围的上述调节作用。这些结论丰富了员工非正式领导力涌现的机制,为中国组织情境下企业激发员工积极性发挥提供了管理启示。

关键词：分布式领导非正式领导力涌现集体主义氛围建设性责任知觉

The interactive effect of temperature and fertilizer types determines the dominant microbes in nitrous oxide emissions and the dicyandiamide efﬁcacy in a veg.table soil

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Soil Ecolog. letters 2024年第3期6卷 121-133页

作者： Xiaoya Xu Haiyang.Liu Yaowei Liu didier lesueur Laetitia Herrmann Hong.ie di Caixian Tang.Jianming.Xu Yong.Li Zhejiang.Provincial Key Laboratory of Ag.icultural Resources and Environment College of Environmental and Resource SciencesZhejiang UniversityHangzhou 310058China Colleg. of g.og.aphy and Environment Shandong Normal UniversityJinan 250014China Centre de Coopération Internationale en Recherche Ag.onomique pour le Développement(CIRAD) UMR Eco&SolsHanoiVietnam Eco&Sols Universitéde Montpellier(UMR)CIRADInstitut National de Recherche pour l’Agriculturel’Alimentation et l’Environnement(INRAE)Institut de Recherche pour le Développement(IRD)Montpellier SupAgro34060 MontpellierFrance Alliance of Biodiversity International and International Center for Tropical Ag.iculture(CIAT) Asia hubCommon Microbial Biotechnology Platform(CMBP)HanoiVietnam School of Life and Environmental Sciences Faculty of ScienceEngineering and Built Environment–Deakin UniversityMelbourneVIC 3125Australia Rubber Research Institute Chinese Academy of Tropical Agricultural SciencesHaikou 571737China La Trobe Institute for Sustainable Ag.iculture and Food Department of AnimalPlant&Soil SciencesLa Trobe UniversityBundooraVic 3086Australia

Heat waves associated with g.obal warming.and extreme climates would arouse serious consequences on nitrog.n(N)***,the responses of the functional g.ilds to different temperatures,especially hig. temperature and the cascading.effect on N_(2)O emissions remain *** incubation study was conducted to examine the effect of different temperatures(20°C,30°C,and 40°C)and fertilizer types(urea and manure)on N_(2)O-producers and N_(2)O-reducers,as well as the efficacy of dicyandiamide(DCD)on N_(2)O emissions in a veg.table *** showed that ammonia oxidizers and nirS-type denitrifiers were well adapted to hig. temperature(40°C)with manure application,while the fung.l nirK-denitrifiers had better tolerance with urea *** nosZ clade I microbes had a strong.adaptability to various temperatures reg.rdless of fertilization type,while the g.owth of nosZ clade II g.oup microbes in non-fertilized soil(control)were sig.ificantly inhibited at hig.er *** N_(2)O emissions were sig.ificantly decreased with increasing.temperature and DCD application(up to 60%,even at 40°C).Under hig. temperature conditions,fung.l denitrifiers play a sig.ificant role in N-limited soils(non-fertilized)while nirS-type denitrifiers was more important in fertilized soils in N_(2)O emissions,which should be specially targ.ted when mitig.ting.N_(2)O emissions under g.obal warming.climate.

关键词： nitrog.n fertilizer microorg.nisms nitrification inhibitor bacteria archaea fung.

Al和Cr协同作用提高核用高强钢耐水蒸气氧化性能

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金属学报 2024年第3期60卷 357-366页

作者：彭祥阳张乐李聪聪侯硕刘迪周建明路广遥蒋虽合中广核研究院有限公司设备研究所深圳518000 北京科技大学新金属材料国家重点实验室北京100083

前期研发的Fe-Ni-Al基超高强度马氏体时效钢表现出了良好的力学和抗辐照性能,然而典型Cr_(2)O_(3)氧化保护膜的耐热钢在轻水反应堆高温高压含水蒸气的服役环境中极易失效,亟待研发兼具抗高温水蒸气氧化、优异力学和抗辐照性能的先进材... 详细信息

前期研发的Fe-Ni-Al基超高强度马氏体时效钢表现出了良好的力学和抗辐照性能,然而典型Cr_(2)O_(3)氧化保护膜的耐热钢在轻水反应堆高温高压含水蒸气的服役环境中极易失效,亟待研发兼具抗高温水蒸气氧化、优异力学和抗辐照性能的先进材料。本工作在前期研发的Fe-Ni-Al系超高强度马氏体时效钢基础上添加不同含量的Cr元素,在保持新型马氏体钢优异力学性能的同时,对其在干燥空气和含水蒸气环境中的氧化性能进行研究。采用非自耗真空电弧炉制备合金铸锭,并对时效处理后的高强钢进行600℃干燥空气和潮湿空气2种环境中的抗氧化性能测试,对氧化后样品的表面和截面形貌进行微观组织表征。结果表明,添加9%Cr后的Fe-13Ni-2.3Al高强钢在600℃空气+10%水蒸气的气氛中氧化100 h的平均单位面积增重仅为0.1 mg.cm^(2),是添加5%Cr的Fe-13Ni-2.3Al高强钢和Fe-18Ni-3Al马氏体时效钢的1/50。对氧化后高强钢微观组织表征分析表明,在Al和Cr元素协同作用下,Fe-13Ni-9Cr-2.3Al高强钢在600℃空气+10%水蒸气条件下表面自发形成了富Fe、Cr、Al的复合氧化膜,提高了抗高温水蒸气氧化性能,其中Cr通过第三组元效应降低氧化物膜-基体界面氧分压,从而促进在高温水蒸气条件下在基体表面形成致密连续的富Al氧化膜。

关键词：超高强度钢水蒸气氧化氧化膜第三组元效应协同效应