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IEEE/CAA Journal of Automatica Sinica 2021年第8期8卷 1465-1476页

作者： Donglei zheng le Zhou Zhihuan Song State Key Laboratory of Industrial Control Technology College of Control Science and EngineeringZhejiang UniversityHangzhou 310027China Automation and Electrical Engineering Zhejiang University of Science&TechnologyHangzhou 310023China

In practical process industries,a variety of online and offline sensors and measuring instruments have been used for process control and monitoring purposes,which indicates that the measurements coming from different sources are collected at different sampling *** build a complete process monitoring strategy,all these multi-rate measurements should be considered for data-based modeling and *** this paper,a novel kernel multi-rate probabilistic principal component analysis(K-MPPCA)model is proposed to extract the nonlinear correlations among different sampling *** the proposed model,the model parameters are calibrated using the kernel trick and the expectation-maximum(EM)***,the corresponding fault detection methods based on the nonlinear features are ***,a simulated nonlinear case and an actual pre-decarburization unit in the ammonia synthesis process are tested to demonstrate the efficiency of the proposed method.

关键词： Fault detection kernel method multi-rate process probability principal component analysis(PPCA)

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合金对铸铁局部重熔强化的影响

沈阳工业大学学报 2001年第2期23卷 110-112,119页

作者：刘乐昕刘政军安希中林克光沈阳工业大学材料科学与工程学院辽宁沈阳110023

针对提高铸铁耐磨性的问题，介绍了用 TIG电弧对涂敷合金元素的灰铸铁表面进行局部重熔处理时，合金种类及合金加入量对试样表面性能的影响 .并在不同条件下，对重熔层的相结构、元素分布、显微组织、硬度和耐磨性进行了测试和分析 .结... 详细信息

针对提高铸铁耐磨性的问题，介绍了用 TIG电弧对涂敷合金元素的灰铸铁表面进行局部重熔处理时，合金种类及合金加入量对试样表面性能的影响 .并在不同条件下，对重熔层的相结构、元素分布、显微组织、硬度和耐磨性进行了测试和分析 .结果表明，合金化可显著提高 TIG重熔处理产生的灰铸铁表面强化效果，使表面性能有很大提高 .

关键词：局部重熔钨极氩弧硬度耐磨性灰铸铁表面强化合金 TIG电弧

Monthly composites from Sentinel-1 and Sentinel-2 images for regional major crop mapping with Google Earth Engine

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Journal of Integrative Agriculture 2021年第7期20卷 1944-1957页

作者： LUO Chong LIU Huan-jun LU Lii-ping LIU zheng-rong KONG Fan-chang ZHANG xin-le Northeast Institute of Geography and Agroecology Chinese Academy of SciencesChangchun 130102P.R.China School of Public Adminstration and Law Northeast Agricultural UniversityHarbin 150030P.R.China

Rapid and accurate access to large-scale,high-resolution crop-type distribution maps is important for agricultural management and sustainable agricultural *** to the limitations of remote sensing image quality and data processing capabilities,large-scale crop classification is still *** study aimed to map the distribution of crops in Heilongjiang Province using Google Earth Engine(GEE)and Sentinel-1 and Sentinel-2 *** obtained Sentinel-1 and Sentinel-2 images from all the covered study areas in the critical period for crop growth in 2018(May to September),combined monthly composite images of reflectance bands,vegetation indices and polarization bands as input features,and then performed crop classification using a Random Forest(RF)*** results show that the Sentinel-1 and Sentinel-2 monthly composite images combined with the RF classifier can accurately generate the crop distribution map of the study area,and the overall accuracy(OA)reached 89.75%.Through experiments,we also found that the classification performance using time-series images is significantly better than that using single-period *** with the use of traditional bands only(i.e.,the visible and near-infrared bands),the addition of shortwave infrared bands can improve the accuracy of crop classification most significantly,followed by the addition of red-edge *** common vegetation indices and Sentinel-1 data to the crop classification improved the overall classification accuracy and the OA by 0.2 and 0.6%,respectively,compared to using only the Sentinel-2 reflectance *** analysis of timeliness revealed that when the July image is available,the increase in the accuracy of crop classification is the *** the Sentinel-1 and Sentinel-2 images for May,June,and July are available,an OA greater than 80%can be *** results of this study are applicable to large-scale,high-resolution crop classification and provide key technologies f

关键词： Sentinel-1 Sentinel-2 monthly composites crop mapping Google Earth Engine

First record of ostracods from the Upper Ordovician red-coloured marine sandstones of the Tierekeawati Formation in Tarim Basin, NW China: implications on palaeoenvironment and palaeobiogeography

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Journal of Palaeogeography 2020年第3期9卷 378-387页

作者： Jun-Jun Song Yi-xin Shen Peng Tang Xiao-le Zhang Qi-Jian Li zheng-Jiang Luo Nanjing Institute of Geology and Palaeontology Chinese Academy of SciencesNanjing 210008Jiangsu ProvinceChina Center for Excellence in Life and Paleoenvironment Chinese Academy of SciencesNanjing 210008Jiangsu ProvinceChina College of Geoscience and Technology China University of Petroleum(East China)Qingdao 266580Shandong ProvinceChina State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008Jiangsu ProvinceChina PetroChina xinjiang Oilfield Company Research Institute of Experiment and DetectionKaramay 834000Xinjiang Uygur Autonomous RegionChina

Ostracods are described for the first time from the red-coloured marine sandstones of Arisu section(Arisu red beds)of the Upper Ordovician Tierekeawati Formation in Kalpin area of northwestern Tarim Basin, xinjiang Uygur Autonomous Region(xinjiang), Northwest China. Twenty-two species belonging to thirteen genera are described and figured. The ostracod fauna suggests a probable Sandbian–Katian age for these beds. The palaeoecological assemblage of ostracod fauna implies the deposition in a nearshore-offshore environment during a regression when the Arisu red beds of the Tierekeawati Formation were laid down in the Tarim Basin. Many cosmopolitan and provincial genera were present in diversified ostracod fauna of the Arisu red beds, suggesting the possible biogeographic relationships among the Tarim, Tibet, and South China plates, as well as Europe and North America continents during the Late Ordovician. Ostracods experienced faunal exchanges between Laurentia and the Tarim Plate during the Late Ordovician Period.

关键词： Ostracods Late Ordovician Arisu section Tierekeawati Formation Kalpin area Tarim Basin GOBE STTS

Artificial intelligence in cancer target identification and drug discovery

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Signal Transduction and Targeted Therapy 2022年第6期7卷 1951-1974页

作者： Yujie You xin Lai Yi Pan Huiru zheng Julio Vera Suran Liu Senyi Deng le Zhang College of Computer Science Sichuan UniversityChengdu 610065China Laboratory of Systems Tumor Immunology Friedrich-Alexander-Universität Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenErlangen 91052Germany Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesRoom D5131068 Xueyuan AvenueShenzhen University TownShenzhen 518055China School of Computing Ulster UniversityBelfast BT151EDUK Institute of Thoracic Oncology Department of Thoracic SurgeryWest China HospitalSichuan UniversityChengdu 610065China Key Laboratory of Systems Biology Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesChinese Academy of SciencesHangzhou 310024China Key Laboratory of Systems Health Science of Zhejiang Province Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China

Artificial intelligence is an advanced method to identify novel anticancer targets and discover novel drugs from biology networks because the networks can effectively preserve and quantify the interaction between components of cell systems underlying human diseases such as ***,we review and discuss how to employ artificial intelligence approaches to identify novel anticancer targets and discover ***,we describe the scope of artificial intelligence biology analysis for novel anticancer target ***,we review and discuss the basic principles and theory of commonly used network-based and machine learning-based artificial intelligence ***,we showcase the applications of artificial intelligence approaches in cancer target identification and drug *** together,the artificial intelligence models have provided us with a quantitative framework to study the relationship between network characteristics and cancer,thereby leading to the identification of potential anticancer targets and the discovery of novel drug candidates.

关键词： drugs cancer drug

Dynamic Frequency Support and DC Voltage Regulation Approach for VSC-MTDC Systems

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CSEE Journal of Power and Energy Systems 2023年第2期9卷 645-658页

作者： Chongru Liu Haoyu Liu Siwen Jiang le zheng State Key Laboratory for Alternate Electrical Power System with Renewable Energy Sources North China Electric Power UniversityBeijing 102206China

When an additional frequency control is implemented in the voltage source converter-based multi-terminal high voltage direct current(VSC-MTDC)system,the DC grid is capable of responding to a frequency disturbance in the AC ***,the original additional frequency control may cause the DC voltage to exceed the limit when providing power for a severe frequency disturbance,threatening the security of the DC system.A novel dynamic additional frequency control strategy for the VSC-MTDC system is developed based on the relationship between the DC voltage and the frequency droop coefficient.A dynamic frequency droop coefficient is designed to adaptively adjust the support power of the DC grid,balancing the frequency regulation of the disturbed AC system and the voltage stability of the DC grid.A DC voltage recovery method based on multi-converter cooperation is proposed to cope with the DC voltage deviation caused by the additional frequency *** validate the advantages and satisfactory performance of the proposed method during power disturbances with different severities and for the process of DC voltage recovery.

关键词： Additional frequency control DC voltage recovery module dynamic frequency droop coefficient VSCMTDC

Current Progress and Future Perspectives of Electrolytes for Rechargeable Aluminum-Ion Batteries

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Energy & Environmental Materials 2023年第1期6卷 25-42页

作者： Dongwei Ma Du Yuan Carlos Ponce de leon zheng Jiang xin Xia Jiahong Pan MOE Key Laboratory of Resources and Environmental Systems Optimization College of Environmental Science and EngineeringNorth China Electric Power UniversityBeijing 102206China College of Materials Science and Engineering Changsha University of Science and TechnologyChangsha 410004China Electrochemical Engineering Department of Engineering and Physical SciencesUniversity of SouthamptonSouthampton UK Beijing Key Laboratory of Novel Thin Film Solar Cells North China Electric Power UniversityBeijing 102206China

Aluminum-ion batteries(AIBs)with Al metal anode are attracting increasing research interest on account of their high safety,low cost,large volumetric energy density(≈8046 mA h cm−3),and environmental ***,the reversible Al electrostripping/deposition is achieved with the rapid development of room temperature ionic liquids,and rapid progress has been made in fabricating high-performance and durable AIBs during the past *** review provides an integrated comprehension of the evolution of AIBs and highlights the development of various non-aqueous and aqueous electrolytes including high-temperature molten salts,room temperature ionic liquids,and gel–polymer *** critical issues on the interplay of electrolytes are outlined in terms of the voltage window span,the effective ion species during charge storage(Al 3+or Al x Cl?y)and their underlying charge transfer(e.g.,interfacial transfer and diffusion),and the solid electrolyte interface formation and its *** the critical insight,future perspectives on how to practically design feasible AIBs are given.

关键词： aluminum-ion batteries electrochemical energy storage electrolytes ionic liquids solid electrolyte interface

Regularity for P-Harmonic Type Systems with the Gradients below the Controllable Growth

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Acta Mathematica Sinica,English Series 2006年第6期22卷 1757-1766页

作者： Shen Zhou zheng Shu le ZHAO Department of Mathematics Beijing Jiaotong University Beijing 100044 P. R. China

In this paper, we shall establish that each weak solution of p-harmonic type systems with the gradients below the controllable growth belongs to, Holder continuity spaces with any HSlder exponent α∈ [0, 1）. Furthermore, we can obtain that the gradients of the corresponding weak solutions also belong to locally Hoelder continuity spaces with some Hoelder exponent. Keywords controllable growth, p-harmonic systems, full regularity MR（2000） Subject Classification 35J60, 35B65

关键词： controllable growth p-harmonic systems full regularity

Proton production,regulation and pathophysiological roles in the mammalian brain

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Neuroscience Bulletin 2012年第1期28卷 1-13页

作者： Wei-zheng Zeng Tian-le Xu Neuroscience Division Department of Biochemistry and Molecular Cell Biology Institute of Medical Sciences ShanghaiJiao Tong University School of Medicine Shanghai 200025 China Institute of Neuroscience and State Key Laboratory of Neuroscience Shanghai Institutes for Biological Sciences ChineseAcademy of Sciences Shanghai 200031 China

The recent demonstration of proton signaling in C. elegans muscle contraction suggests a novel mechanism for proton-based intercellular communication and has stimulated enthusiasm for exploring proton signaling in higher organ- isms. Emerging evidence indicates that protons are produced and regulated in localized space and time. Furthermore, identification of proton regulators and sensors in the brain leads to the speculation that proton production and regulation may be of major importance for both physiological and pathological functions ranging from nociception to learning and memory. Extracellular protons may play a role in signal transmission by not only acting on adjacent ceils hut also af- fecting the cell from which they were released. In this review, we summarize the upstream and downstream pathways of proton production and regulation in the mammalian brain, with special emphasis on the proton extruders and sensors that are critical in the homeostatic regulation of pH, and discuss their potential roles in proton signaling under normal and pathophysiological conditions.

关键词： proton extruders proton sensors pH homeostasis proton signaling pH microdomains local accumulation

Study of human B7 homolog 1 expression in patients with hepatitis B virus infection

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World Journal of Gastroenterology 2012年第28期18卷 3681-3695页

作者： Wen-Jin Zhang Hai-Yang Xie xin Duan Yun-le Wan Chuan-Hui Peng Shao-Hua Shi Rong Su Zhang-Hui zheng le-Lin Pan Lin Zhou Shu-Sen zheng Division of Hepatobiliary and Pancreatic Surgery Department of Surgery First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 Zhejiang Province China Key Laboratory of Combined Multi-organ Transplantation Ministryof Public Health Hangzhou 310003 Zhejiang Province China Department of Hepatobiliary Surgery Sun Yat-SenMemorial Hospital Sun Yat-Sen University Guangzhou 510120Guangdong Province China

AIM: To further investigate the role of human B7 homolog 1 (B7-H1) in the mechanism of persistent hepatitis B virus (HBV) infection. METHODS: Peripheral and intra-hepatic B7-H1 expression were compared by flow cytometry and immunochemical staining between two 2 distinct groups, one being chronic HBV tolerance patients (CHB-T) and the other being acute hepatitis B patients (AHB). B7-H1 mRNA expression level was also compared by real time polymerase chain reaction between CHB-T and AHB patients. The location of intra-hepatic B7-H1 and CD40 expression were analyzed by immunofluorescence. The levels of B7-H1 and CD40 expression on cultured myeloid dendritic cells (mDCs) with or without hepatitis B surface antigen (HBsAg) treatment were analyzed dynamically by flow cytometry. Intracellular interferon-γ (IFN-γ) staining and the stimulatory capacity of mDC of cultured mDC with or without HBsAg treatment were also compared by flow cytometry. RESULTS: Peripheral B7-H1 expression on mDCs was increased significantly in AHB compared to CHB-T patients (P levated serum HBsAg load. In contrast, there were indeed increased B7-H1-positive cells in situ in the liver tissue from AHB. In vitro analysis showed the parallel upregulation of B7-H1 and CD40 on CD11c+ mDCs after the onset of stimulation. Addition of recombinant hepatitis B surface antigen (rHBsAg) significantly decreased CD40 expression (P leucocyte reaction (MLR) system. With rHBsAg pretreatment, in a carboxyfluorescein diacetate succinimidyl ester (CFSE) labeled MLR system at a ratio of 1:5 responder cell-stimulator cell (R/S), the C

关键词： Hepatitis B virus Hepatitis B Human B7 homolog 1 Immune tolerance Co-stimulatory molecule