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Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus

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World Journal of Diabetes 2024年第11期15卷 2203-2219页

作者： Yi-Bo Tang le-sha wang Yi-Hui Wu Li-Xia Zhang Lu-Yao Hu Qi Wu Meng-Lin Zhou Zhao-Xia Liang Department of Obstetrics Women's Hospital School of MedicineZhejiang UniversityHangzhou 310006Zhejiang ProvinceChina Department of Obstetrics Shaoxing People’s HospitalShaoxing 312000Zhejiang ProvinceChina

BACKGROUND Gestational diabetes mellitus(GDM)women require prenatal care to minimize short-and long-term *** mechanism by which exercise during pregnancy affects organ development and whether glucose transporter(GLUT)1 plays a role in GDM offspring organ development remains *** To determine the effect of exercise during pregnancy on the cardiac,hepatic and renal development of GDM mother’s *** Placenta samples were collected from humans and *** mouse models were created using streptozotocin along with a GDM with exercise *** hearts,livers and kidneys of 3-and 8-week-old offspring were collected for body composition analysis and *** effects of high glucose levels and hypoxia were investigated using HTR8/*** and wound-healing assays were performed to assess cell *** accompanied with TUNEL and Ki67 staining was used to explore apoptosis and *** Exercise during pregnancy downregulated the GLUT1 and hypoxia inducible factor-1αexpression in placenta from individuals with *** chloride induced hypoxia and high glucose levels also significantly decreased migration and apoptosis of HTR8/SVneo *** addition,exercise reduced inflammatory cell infiltration in the liver and decreased the tubular vacuolar area in the kidneys of *** GDM affects the growth and development of organs in *** during pregnancy can reverse adverse effects of GDM on the development of the heart,liver,and kidney in offspring.

关键词： Gestational diabetes mellitus Exercise Glucose transporter 1 Hypoxia inducible factor-1α Placenta Offspring

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The Efficacy of Electromyographic Biofeedback Combined with Swallowing Training on Post- Stroke Dysphagia

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Journal of Clinical and Nursing Research 2024年第5期8卷 309-314页

作者： le wang Yu Zhang Xiaohui wang Zhi Li sha Chang Department of Neurology Shaanxi Provincial People’s HospitalXi’an 710068ShaanxiChina Department of Gynecology Shaanxi Provincial People’s HospitalXi’an 710068ShaanxiChina

Objective:This paper focuses on the research and discussion of the efficacy of electromyographic biofeedback combined with swallowing training on post-stroke ***:This study randomly sampled and analyzed 68 patients with post-stroke dysphagia from January 2023 to December 2023,34 cases of swallowing training intervention were grouped as the control group,and 34 cases of electromyography biofeedback combined with swallowing training intervention were grouped as the study group,and the clinical therapeutic effects of the two groups of patients after receiving the two different modes of intervention were ***:The swallowing function of patients in both groups improved,and the VFSS score of patients in the seminar group was significantly higher than that of the control group,indicating that the clinical efficacy of the seminar group was more *** nasal feeding tube extraction rate,extraction time,and quality of life scores of the seminar group were better than those of the control group(Plectromyography biofeedback combined with swallowing training mode can significantly improve their swallowing *** effective intervention can not only shorten the time for patients to remove the nasal feeding tube but also help to improve the quality of life of patients,which is worth using.

关键词： Electromyographic biofeedback Stroke Swallowing training

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Research Progress in Integrated Chinese and Western Medicine Health Management for School-Age Children with Asthma

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Journal of Clinical and Nursing Research 2024年第7期8卷 85-90页

作者： Hanlu Zhang le wang sha wang Nannan Ma Li Mei shaanxi Provincial People’s Hospital Children’s Hospital Xi’an 710000Shaanxi ProvinceChina

Objective:The purpose of this study is to investigate the application of Chinese and Western medicine in the health management of school-age children with asthma and its research progress,with a view to providing a more comprehensive and effective management strategy for the ***:Using the method of literature review,this study systematically searched and analyzed the relevant studies on the combination of Chinese and Western medicine in the health management of school-aged children with asthma in recent years,focusing on Chinese medicine treatment,Western medicine treatment,and the combined health management of Chinese and Western ***:Chinese medicine treatment,Western medicine treatment,and the health management mode of combining Chinese and Western medicine showed unique advantages in school-age asthmatic *** the comprehensive use of Chinese medicine’s diagnosis and treatment,Chinese medicine conditioning,Chinese medicine characteristic therapy,and Western medicine’s modern medical methods,it not only effectively relieved asthma symptoms but also significantly improved the quality of life of the *** the same time,this management mode also focuses on the psychological guidance and family care of the children,forming an all-round and multi-level health management ***:The health management strategy of combining Chinese and Western medicine has a broad application prospect in school-age asthmatic children,and its specific interventions and mechanisms of action should be further studied to provide more scientific and systematic guidance for clinical practice.

关键词： School-age children with asthma Chinese medicine treatment Western medicine treatment Health management

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A Study of Health Prescribing for Children with Tourette’s Disorders in Children’s Health Education Specialty Care Clinics

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Journal of Clinical and Nursing Research 2024年第7期8卷 261-266页

作者： Wenping Yang le wang sha wang Nannan Ma Li Mei shaanxi Provincial People’s Hospital Xi’an 710000Shaanxi ProvinceChina

Objective:This study designs and implements the health prescription of children’s health education specialized nursing clinic based on the physical and mental characteristics of children with Tourette’s ***:Applying the evidence-based nursing model and nursing intervention theory based on the survey research by searching China Knowledge Network,Wanfang Database and Wipro Chinese Science and Technology Journal Database,the study collected the literature on the health prescription intervention research in children’s Tourette’s disorders health education in children’s health education of specialized nursing outpatient clinic for review and combined with the specialty characteristics to formulate“Children’s Tourette’s Disorder Health Education Prescription.”Results:Tourette’s syndrome in children is a common pediatric neurological disorder,mainly manifested as involuntary,rapid and repeated muscle twitching and vocal tics,which brings serious psychological pressure and life disturbance to the affected ***:For children with Tourette’s syndrome,healthcare professionals should give enough care and understanding to the children and their parents,provide timely and effective health education to them,help them improve their bad behavioral habits,establish correct cognitive attitudes,enhance self-confidence,improve patient compliance,reduce the frequency of recurrence,reduce the incidence of complications and promote children’s physical and mental health development.

关键词： Children’s health education Specialty care clinic Childhood Tourette’s disorder Health prescription

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Research Progress on Combined Chinese and Western Medicine Treatment of Mycoplasma pneumoniae Pneumonia in Children

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Journal of Clinical and Nursing Research 2024年第6期8卷 117-122页

作者： Wenping Yang le wang sha wang Nannan Ma Li Mei shaanxi Provincial People's Hospital Children's Hospital Xi'an 710000Shaanxi ProvinceChina

With the continuous development of medical technology,combined treatment of Chinese and Western medicine has gradually become a research *** a common disease in pediatrics,the treatment of Mycoplasma pneumoniae pneumonia(MPP)in children is also being explored and *** article summarizes the research progress of combined Chinese and Western medicine treatment of MPP in children in recent years,aiming to provide a useful reference for the combined treatment of MPP in *** article firstly introduces the etiology and pathogenesis of MPP in children,thereafter briefly introduces the Western anti-infective treatment and traditional Chinese medicine(TCM)diagnosis and treatment of MPP in children,and lastly introduces the methods of combined treatment of TCM and Western medicine in *** article points out that the combination of Chinese and Western medicine can give full play to the overall regulation of Chinese medicine and the precise treatment advantages of Western medicine,improve the therapeutic effect,reduce the use of antibiotics,and lower the recurrence rate of the disease,which is worthy of further research and promotion.

关键词： Children Mycoplasma pneumoniae pneumonia Combined Chinese and Western medicine Research progress

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Advances in the Study of Psychological Stress and Eating Behavior in Children and Adolescents

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Journal of Clinical and Nursing Research 2024年第7期8卷 191-195页

作者： Ting He le wang sha wang Nannan Ma Li Mei Mengdan Zheng shaanxi Provincial People’s Hospital Children’s Hospital Xi’an 710000Shaanxi ProvinceChina

With the rapid development and change in society,children and adolescents are facing more and more psychological pressure,which comes not only from academic performance and interpersonal relationships but also from family environment,social expectations and other *** stress not only affects the mental health of children and adolescents but is also closely related to their eating ***,exploring the relationship between psychological stress and eating behaviors is of great significance in promoting the physical and mental health development of children and *** on this,the study reviewed the research progress on the relationship between psychological stress and eating behavior of children and adolescents in recent *** relationships between psychological stress and general eating behaviors,abnormal eating behaviors and eating disorders were successively reviewed,and the related physiological mechanisms were explored with a view to providing a scientific basis for mental health education and eating behavior intervention for children and adolescents.

关键词： Children Adolescents Psychological stress Eating behavior Research progress

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分组密码复杂线性层可分性传播的MILP刻画方法

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软件学报 2024年第4期35卷 1980-1992页

作者：黄明张莎莎洪春雷曾乐向泽军湖北大学数学与统计学学院湖北武汉433062 上海大学通信与信息工程学院上海200444 Faculty of Science The University of MelbourneMelbourne VIC3010Australia

混合整数线性规划(MILP)作为一种自动化搜索工具,被广泛地应用于搜索分组密码的差分、线性、积分等密码性质.提出一种基于动态选取策略构建MILP模型的新技术,该技术在不同的条件下采用不同的约束不等式刻画密码性质的传播.具体地,从可... 详细信息

混合整数线性规划(MILP)作为一种自动化搜索工具,被广泛地应用于搜索分组密码的差分、线性、积分等密码性质.提出一种基于动态选取策略构建MILP模型的新技术,该技术在不同的条件下采用不同的约束不等式刻画密码性质的传播.具体地,从可分性出发根据输入可分性汉明重量的不同,分别采用不同的方法构建线性层可分性传播的MILP模型.最后,将该技术应用于搜索uBlock和Saturnin算法的积分区分器.实验结果表明:对于uBlock128算法,该技术可以搜索到比之前最优区分器多32个平衡比特的8轮积分区分器.除此之外,搜索到uBlock128和uBlock256算法比之前最优区分器更长一轮的9和10轮积分区分器.对于Saturnin256算法,同样搜索到比之前最优区分器更长一轮的9轮积分区分器.

关键词：混合整数线性规划可分性线性层汉明重量积分区分器

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人参上市药品研究进展

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中国中药杂志 2024年第7期49卷 1717-1724页

作者：覃思意赖嘉敏贾彬王乐琪李莎莎严诗楷肖雪广东药科大学、广东省代谢病中西医结合研究中心(中医药研究所) 广东广州510006 国家药品监督管理局药品快速检验技术重点实验室(广东省药品检验所) 广东广州510663 广州中医药大学第二附属医院广东广州510120 上海交通大学药学院上海200240

人参被誉为“百草之王”,是一种重要的药用植物,其药用部位包括根、茎叶、花和果实,以根部最为常用。人参的主要活性成分包括三萜皂苷、多糖和多肽及挥发油等,人参化学成分及其活性代谢物赋予其多种药理作用,应用于治疗疾病和发挥保健... 详细信息

人参被誉为“百草之王”,是一种重要的药用植物,其药用部位包括根、茎叶、花和果实,以根部最为常用。人参的主要活性成分包括三萜皂苷、多糖和多肽及挥发油等,人参化学成分及其活性代谢物赋予其多种药理作用,应用于治疗疾病和发挥保健功能。人参作为传统中药资源,现已有多种人参制剂获得药品注册并上市,包括人参片、人参口服液、人参注射液等,在调节免疫功能、辅助治疗肿瘤、抗疲劳、延缓衰老、改善糖脂代谢、治疗心血管疾病及抗炎镇痛各方面展现出良好的临床疗效,相关药品的生产工艺和质量标准对保证其药效具有重要意义。该文基于人参“大补元气,补脾益肺,生津止渴、安神益智”的理论指导,较为系统地总结了药用植物人参及源于人参的相关上市药品的临床应用进展,同时关注人参上市药品及相关制品的再开发,为进一步挖掘人参的药用价值和保健功能提供参考。综述以上内容,作为深度开发人参及人参相关上市药的重要基础,为拓展人参的应用提供更多可能性。

关键词：人参上市药品临床应用研究进展潜在价值

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Phase-field modeling of epitaxial growth with the Ehrlich-Schwoebel barrier: Model validation and application

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Science China(Technological Sciences) 2015年第4期58卷 753-762页

作者： DONG Xiang lei XING Hui sha sha CHEN Chang le NIU Li Wei wang Jian Yuan JIN Ke Xin shanxi Key Laboratory for Condensed Matter Structure and Properties Department of Applied Physics Northwestern Polytechnical University

In this paper,we introduce different forms of mobility into a quantitative phase-field model to produce arbitrary Ehrlich-Schwoebel(ES)*** studies were carried out in the one-side step-flow model,which showed that the original mobility not only induces the ES effect,but also leads to larger numerical instability with increase of the step ***,another modified form of the ES barrier is proposed,and is found to be more suitable for large-scale *** applications were performed on the wedding-cake structure,coarsening and coalescence of islands and spiral *** results show that the ES barrier exhibits more significant kinetic effects at the larger deposition rates by limiting motions of atoms on upper steps,leading to aggregation on the top layers,as well as the roughening of growing surfaces.

关键词： epitaxial growth phase-field method Ehrlich-Schwoebel barrier kinetics interfacial

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Design,synthesis and applications of functional zirconium-based metal-organic frameworks

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Science China Chemistry 2023年第12期66卷 3383-3397页

作者： le Shi Zhenning Yang Fanrui sha Zhijie Chen Stoddart Institute of Molecular Science Department of ChemistryZhejiang UniversityHangzhou 310058China Zhejiang-Israel Joint Laboratory of Self-Assembling Functional Materials ZJU-Hangzhou Global Scientific and Technological Innovation CenterZhejiang UniversityHangzhou 311215China Department of Chemistry and International Institute for Nanotechnology Northwestern UniversityEvanstonIllinois 60208United States

Zirconium-based metal-organic frameworks(Zr-MOFs)have been explored for applications including but not limited to water adsorption,gas storage and separation,heterogeneous catalysis,and chemical ***-MOFs serve as a major class of functional MOFs thanks to their high thermal,chemical and hydrolytic stability,large surface area,and tunable structures with the versatile *** this work,we highlight the design and synthesis of zirconium-based MOFs as well as their ***,we demonstrate how reticular chemistry can direct the rational design and synthesis of functional ZrMOFs and describe their structure–property *** addition,we feature synthetic strategies,including isoreticular expansion,linker functionalization,node functionalization,and defect engineering,as toolkits to construct tailored material for specific applications.

关键词： metal-organic frameworks Zr-MOFs reticular chemistry structure–property relationship

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