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Individualized minimally invasive treatment for adult testicular hydrocele: A pilot study

World Journal of Clinical Cases 2019年第6期7卷 727-733页

作者： le lin Huai-Shan Hong Yun-Liang Gao Jin-Rui Yang Tao Li Qing-Guo Zhu Lie-Fu Ye Yong-Bao Wei Shengli Clinical Medical College of Fujian Medical University Department of Urology Fujian Provincial Hospital Department of Urology the Second Xiangya HospitalCentral South University

BACKGROUND Hydrocelectomy is the gold standard for the treatment of hydrocele,but it often causes complications after surgery,including hematoma,infection,persistent swelling,hydrocele recurrence,and chronic pain. In recent years,several methods for minimally invasive treatment of hydrocele have been introduced,but they all have limitations. Herein,we introduce a new method of individualized minimally invasive treatment for *** To present a new method for the treatment of adult testicular *** Fifty-two adult patients with idiopathic testicular hydrocele were included. The key point of this procedure was that the scope of the resection of the sheath of the tunica vaginalis was determined according to the maximum diameter(d) of the effusion measured by ultrasound and the maximum diameter of the portion of the sheath pulled out of the scrotum was approximately πd/2. The surgical procedure consisted of a 2-cm incision in the anterior wall of the scrotum,drainage of the effusion,and dissection of part of the sheath of the tunica vaginalis. After the sheath was peeled away to the predetermined target extent,the pulled-out sheath was removed. The intraoperative findings and postoperative complications were *** All patients were successfully treated with a median operation time of 18 *** median maximum diameter of the effusion on ultrasound was 3.5 cm,and the median maximum diameter of the resected sheath was 5.5 cm. Complications occurred in four(7.7%) patients: two(3.8%) cases of mild scrotal edema,one(1.9%) case of scrotal hematoma,and one(1.9%) case of wound infection. All of the complications were grade I-II. Recurrent hydrocele,chronic scrotal pain,and testicular atrophy were not observed during a median follow-up of 12 *** We report a new technique for individualized treatment of testicular hydrocele,which is quantitative and minimally invasive and yields good outcomes. Further study is warranted to verify its potent

关键词： Testicular hydrocele Individual treatment Minimal invasion Complications Scrotoscope

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Pan-immune-inflammation value as a prognostic biomarker for colon cancer and its variation by primary tumor location

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World Journal of Gastroenterology 2024年第33期30卷 3823-3836页

作者： Qian-Yu Wang Wen-Tao Zhong Yi Xiao Guo-le lin Jun-Yang Lu Lai Xu Guan-Nan Zhang Jun-Feng Du Bin Wu Department of General Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Medical Department of General Surgery The First Medical CenterChinese PLA General HospitalBeijing 100853China

BACKGROUND A growing body of research indicates significant differences between left-sided colon cancers(LCC)and right-sided colon cancers(RCC).Pan-immune-inflammation value(PIV)is a systemic immune response marker that can predict the prognosis of patients with colon ***,the specific distinction between PIV of LCC and RCC remains *** To investigate the prognostic and clinical significance of PIV in LCC and RCC *** This multicenter retrospective cohort study included 1510 patients with colon cancer,comprising 801 with LCC and 709 with *** used generalized lifting regression analysis to evaluate the relative impact of PIV on disease-free survival(DFS)in these ***-Meier analysis,as well as univariate and multivariate analyses,were used to examine the risk factors for *** correlation between PIV and the clinical characteristics was statistically analyzed in these *** A total of 1510 patients{872 female patients(58%);median age 63 years[interquartile ranges(IQR):54-71];patients with LCC 801(53%);median follow-up 44.17 months(IQR 29.67-62.32)}were *** was significantly higher in patients with RCC[median(IQR):214.34(121.78-386.72)vs 175.87(111.92-286.84),P227.84)was associated with worse DFS in LCC[PIV-high:Adjusted hazard ratio(aHR)=2.39;95%confidence interval:1.70-3.38;P<0.001]but not in RCC(PIV-high:aHR=0.72;95%confidence interval:0.48-1.08;P=0.114).CONCLUSION These findings suggest that PIV may predict recurrence in patients with LCC but not RCC,underscoring the importance of tumor location when using PIV as a colon cancer biomarker.

关键词： Colon cancer left-sided colon cancer Right-sided colon cancer Pan-immune-inflammation value Systemic inflammatory biomarkers Prognosis

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高精度光纤荧光测温法的稳定性研究

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计量学报 2008年第2期29卷 129-133页

作者：贾丹平林乐乐苑玮琦林应文沈阳工业大学辽宁沈阳110023

荧光测温方法的分析通常是基于指数曲线而进行的,实践中发现实际的余辉曲线与指数曲线有差别,是影响仪器稳定性的关键因素。从荧光发光机理出发,分析了产生非指数的根源,提出了用截断归一法来评价余辉曲线的非指数性,通过几种代表性的... 详细信息

荧光测温方法的分析通常是基于指数曲线而进行的,实践中发现实际的余辉曲线与指数曲线有差别,是影响仪器稳定性的关键因素。从荧光发光机理出发,分析了产生非指数的根源,提出了用截断归一法来评价余辉曲线的非指数性,通过几种代表性的荧光材料的光谱特性和截断归一化分析实验,验证了理论分析的正确性,给出了改善非指数性的措施。在此措施下使测量系统达到0.1℃的分辨率和±0.2℃的精度,可以现场实时进行校准,测温探头可以互换,已用于微波加热医学生物研究中。

关键词：计量学温度测量荧光稳定性归一化

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Time-resolved two-photon excitation fluorescence spectroscopy and microscopy using a high repetition rate streak camera

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Optoelectronics letters 2007年第2期3卷 157-160页

作者： LIU Li-xin QU Ju-le lin Zi-yang WANG lei FU Zhe GUO Bao-ping NIU Han-ben Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education Institute of Optoelectronics Shenzhen University Shenzhen 518060 China

We present a time-resolved two-photon excitation fluorescence spectroscopy and a simultaneous time- and spectrum- resolved multifocal multiphoton microscopy system that is based on a high repetition rate picosecond streak camera for providing time- and spectrum- resolved measurement and imaging in biomedicine. The performance of the system is tested and characterized by the fluorescence spectrum and lifetime analysis of several standard fluorescent dyes and their mixtures. Spectrum-resolved fluorescence lifetime images of fluorescence beads are obtained. Potential applications of the system include clinical diagnostics and cell biology etc.

关键词：时间分辨双光子激发荧光光谱显微镜高重复率皮秒超高速扫描照相机时间-光谱分辨同时测量生物医学

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Earlier application of loading doses of aspirin and clopidogrel decreases rate of recurrent cardiovascular ischemic events for patients undergoing percutaneous coronary intervention

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Chinese Medical Journal 2012年第4期125卷 631-638页

作者： Tang Fa-kuan lin le-jian Hua Ning Lu Hong Qi Zhi Tang Xue-zheng Chinese Peoples Liberat Army Hosp 309 Dept Cardiol Beijing 100091 Peoples R China

Background Aspirin and clopidogrel resistance plays a significant role in the development of cardiovascular ischemic events for ninety patients undergoing percutaneous coronary *** studies have indicated that increasing the dose of antiplatelet drugs maybe a potent method to improve the inhibition of platelet *** Thrombelastograph （TEG） determinations were used to evaluate the effect of antiplatelet *** to the results,90 patients were divided into three groups and given different doses of aspirin and *** patients with both an inhibition rate of aspirin 〉50% and an inhibition rate of clopidogrel 〉50% were defined as the control *** patients with an inhibition rate for aspirin 〈50% and an inhibition rate for clopidogrel 〈50% were defined as the resistance *** in resistance group were randomly assigned to be given a routine dose （100 mg aspirin plus 75 mg clopidogrel per day,which we called a resistance plus routine dose group,R＋R） and a loading dose （200 mg aspirin and 150 mg clopidogrel per day,which we called resistance plus loading dose group,R＋L） of antiplatelet therapy.A 12-month follow-up was observed to examine the change of inhibition rate of antiplatelet therapy and to estimate the relationship between inhibition rate and the occurrence of cardiovascular ischemic *** After 6 months of antiplatelet therapy,the inhibition rate of aspirin in the R＋L group increased from （31.4±3.7）% to （68.6±7.1）%,which was significantly higher than that in R＋R group,（51.9±8.2）% （P 〈0.01）.The inhibition rate of clopidogrel in the R＋L group increased from （22.1±3.8）% to （60.2±7.4）%,which was significantly higher than in the R＋R group,（45.9±4.3）% （P 〈0.01）.The occurrence rates of cardiovascular ischemic events,stent thrombosis,recurrent unstable angina and myocardial infarction in the R＋R group were 20%,36% and 17%,*** was significantly increased compared with that in the

关键词： aspirin resistance clopidogrel resistance thrombelastograph percutaneous coronary intervention cardiovascular ischemic events

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Relationship of left heart size and left ventricular mass with exercise capacity in chronic heart failure

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Chinese Medical Journal 2011年第16期124卷 2485-2489页

作者： SHEN Yu-qin WANG le-min CHE lin SONG Hao-ming ZHANG Qi-ping Department of Cardiology Shanghai Tongji Hospital Affiliated toTongji University Shanghai 200065 China

Background Impaired exercise capacity is one of the most common clinical manifestations in patients with chronic heart failure （CHF）. The severity of reduced exercise capacity is an indicator of disease prognosis. The aim of the current study was to investigate the association between left heart size and mass with exercise capacity. Methods A total of 74 patients were enrolled in the study, with 37 having congestive heart failure （left ventricular ejection fraction （LVEF）〈0.45） and the other 37 with coronary heart disease （by coronary angiography） serving as the control group （LVEF 〉0.55）. Echocardiography and cardiopulmonary exercise test were performed. The multiply linear regression model was used to evaluate the association between echocardiogrphic indices and exercise capacities. Results The study showed that left ventricular end diastolic / systolic diameter （LVEDD/LVESD）, left atrial diameter （LAD） and left ventricular mass index （LVMI） were significantly enlarged in patients with chronic heart failure compared with controls （P 〈0.01）. The VO2AT, Peak VO2, Load AT, and Load Peak in chronic heart failure patients were also significantly reduced compared with controls （P 〈0.05）, VENCO2 slope was increased in patients with chronic heart failure （P 〈0.01）. Multivariate linear regression analysis indicated that the patients＇ exercise capacity was significantly associated with the left heart size and mass, however, the direction and/or strength of the associations sometimes varied in chronic heart failure patients and controls. Load AT correlated negatively with LVEDD in chronic heart failure patients （P=0.012）, while Load AT correlated positively with LVEDD in control patients （P=0.006）. VENCO2 slope correlated positively with LAD （B=0.477, P 〈0.0001） in chronic heart failure patients, while the VENCO2 slope correlated negatively with LAD in control patients （P=0.009）. Conclusion The study indicates that the size of LVEDD and LAD are important determinants of exe

关键词： echocardiography exercise tolerance exercise test heart failure systolic

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Clinical characteristics and risk factors of post-operative intestinal flora disorder following laparoscopic colonic surgery:A propensityscore-matching analysis

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1259-1270页

作者： Gan-Bin Li Chen-Tong Wang Xiao Zhang Xiao-Yuan Qiu Wei-Jie Chen Jun-Yang Lu Lai Xu Bin Wu YiXiao Guo-le lin Department of General Surgery Peking Union Medical College HospitalPeking Union Medical CollegeBeijing 100730China

BACKGROUND Intestinal flora disorder(IFD)poses a significant challenge after laparoscopic colonic surgery,and no standard criteria exists for its diagnosis and *** To analyze the clinical features and risk factors of *** Patients with colon cancer receiving laparoscopic surgery were included using propensity-score-matching(PSM)*** on the occurrence of IFD,patients were categorized into IFD and non-IFD *** clinical characteristics and treatment approaches for patients with IFD were *** regression analysis was performed to identify the risk factors of *** The IFD incidence after laparoscopic surgery was 9.0%(97 of 1073 patients).After PSM,97 and 194 patients were identified in the IFD and non-IFD groups,*** most common symptoms of IFD were diarrhea and abdominal,typically occurring on post-operative days 3 and *** patients were managed conservatively,including modulation of the intestinal flora(90.7%),oral/intravenous application of vancomycin(74.2%),and insertion of a gastric/ileus tube for decompression(23.7%).Multivariate regression analysis identified that preoperative intestinal obstruction[odds ratio(OR)=2.79,95%CI:1.04–7.47,P=0.041]and post-operative antibiotics(OR=8.57,95%CI:3.31–23.49,P<0.001)were independent risk factors for IFD,whereas pre-operative parenteral nutrition(OR=0.12,95%CI:0.06–0.26,P<0.001)emerged as a protective *** A stepwise approach of probiotics,vancomycin,and decompression could be an alternative treatment for *** attention is warranted post-operatively for patients with pre-operative obstruction or early use of antibiotics.

关键词： Colon cancer,Laparoscopy Intestinal flora disorder Clinical characteristics Risk factors

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炭纤维表面特性对复合材料表面性能的影响研究

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炭素技术 2020年第4期39卷 57-61页

作者：林乐乐福州工商学院福建福州350715

为研究炭纤维表面特性对体育器械复合材料表面性能的影响,采用扫描电镜、原子力显微镜和X射线光电子能谱仪等分析圆形截面高强炭纤维和圆形截面T300炭纤维表面物理、化学性能,并深入研究体育器械复合材料界面连接性能、吸湿性能和湿热... 详细信息

为研究炭纤维表面特性对体育器械复合材料表面性能的影响,采用扫描电镜、原子力显微镜和X射线光电子能谱仪等分析圆形截面高强炭纤维和圆形截面T300炭纤维表面物理、化学性能,并深入研究体育器械复合材料界面连接性能、吸湿性能和湿热力学性能。研究结果表明,圆形截面高强炭纤维表面较平滑,比表面积和活性碳原子相对比例较低;而圆形截面T300炭纤维表面较粗糙,比表面积和活性碳原子相对比例较高;圆形截面高强炭纤维体育器械复合材料的界面连接性较差、吸湿性能与湿热力学性能较佳。说明炭纤维表面越粗糙、比表面积越大、活性碳原子比例越高,炭纤维体育器械复合材料界面连接性能越好,但同时吸湿性能与湿热力学性能下降。

关键词：炭纤维表面特性界面连接性能湿热力学性能

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麻醉方式对序贯式双肺移植患者呼吸功能及肺功能的影响

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中国组织工程研究 2014年第27期18卷 4304-4309页

作者：黄乐林解放军第171医院麻醉科江西省九江市332000

背景:在非体外循环的条件下,保证患者在麻醉效果良好的情况下完成序贯式双肺移植,胸段硬膜外复合全静脉麻醉和全静脉麻醉的选择上尚存在争议。目的:观察序贯式双肺移植过程中两种不同的麻醉方式对患者呼吸功能及肺生物学功能的影响。方... 详细信息

背景:在非体外循环的条件下,保证患者在麻醉效果良好的情况下完成序贯式双肺移植,胸段硬膜外复合全静脉麻醉和全静脉麻醉的选择上尚存在争议。目的:观察序贯式双肺移植过程中两种不同的麻醉方式对患者呼吸功能及肺生物学功能的影响。方法:将24例序贯式双肺移植患者分为全静脉麻醉组及硬膜外复合全静脉麻醉组。对两组患者麻醉后单、双肺通气10 min后的氧耗量、二氧化碳排出量、呼吸商和能量消耗进行测定。同时,对比分析两组患者移植过程中去甲肾上腺素、肾上腺素、皮质醇以及血糖水平参数变化。结果与结论:两组患者在移植后6个月、1年及3年的随访调查中,肺功能均得到明显的改善,血气分析状况良好,两组差异无显著性意义。两组患者的并发症发生率、急性排斥反应及死亡率差异均无显著性意义(P>0.05)。麻醉后硬膜外复合全静脉麻醉组单、双肺通气患者的氧耗量、二氧化碳排出量和能量消耗指标均明显高于全静脉麻醉组相同时段对应指标(P0.05)。硬膜外复合全静脉麻醉组单、双肺通气患者的去甲肾上腺素、肾上腺素、皮质醇以及血糖水平均明显低于全静脉麻醉组相同时段对应水平(P0.05)。提示在双肺移植过程中,胸段硬膜外复合全静脉麻醉与全静脉麻醉相比,患者氧耗量、二氧化碳排出量和能量代谢明显增强,可减轻应激反应,且麻醉后代谢、应激情况不受通气方式影响。

关键词：组织构建移植肺移植麻醉应激能量代谢全静脉麻醉硬膜外麻醉肺功能血气分析

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张载理学价值观的主题、体系定位及最高原理

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深圳大学学报（人文社会科学版） 2020年第3期37卷 5-14页

作者：林乐昌陕西师范大学关学研究院陕西西安710062

任何具有普遍意义的价值观,都是人的动机和行为的准则,同时也代表人的信念或信仰。张载因应北宋时期儒学复兴的时代呼唤,对西周原本作为"德政"的德-礼体系从价值观的角度进行了新的诠释,系统阐发了"尊礼"价值观和"贵德"价值观。张载理... 详细信息

任何具有普遍意义的价值观,都是人的动机和行为的准则,同时也代表人的信念或信仰。张载因应北宋时期儒学复兴的时代呼唤,对西周原本作为"德政"的德-礼体系从价值观的角度进行了新的诠释,系统阐发了"尊礼"价值观和"贵德"价值观。张载理学价值观内容丰富,常用德目包括"礼""德""仁""义""智""信""恭""敬""诚",等等。依其重视程度和使用频率可知,"礼"和"德"是其价值观的两个基本类型,"尊礼贵德"是其价值观的主题。"礼"不仅是实现仁、孝等道德价值的途径,而且其本身也具有强烈的价值意义,其性质属于规范伦理或规范价值。"贵德"的核心是"仁""孝","贵德"价值分为仁德价值与孝德价值。张载的价值观在其理学体系中处于"形而中学"层级,发挥着上通与下贯的作用。"尊礼贵德"价值观在生活世界中的方向确定和实施有度,遵循的是作为最高原理的"中正之道"。

关键词：张载价值观礼德 “尊礼贵德” 仁德孝德主题体系定位 “中正之道”

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