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Chinese Chemical letters 2015年第3期26卷 348-352页

作者： Cheng-Xi Zhang Yu-Yuan deng Yi-Yang Zhang Po Yang Yi Gu State Key Laboratory of Polymer Materials Engineering College of Polymer Science and EngineeringSichuan University

To study the synthesis of 3,4-dihydro-2H-3-phenyl-1,3-benzoxazine（benzoxazine）,the reaction paths of phenol,aniline and formaldehyde were investigated by analyzing the synthesis crude *** the aid of high-performance liquid chromatography（HPLC）,chromatographic column and preparative HPLC,seven compounds originated from the crude products were obtained and their chemical structures were *** reaction paths are proposed based on these *** show that Nhydroxymethyl aniline（HMA） derived from the reaction of formaldehyde and aniline is probably the key intermediate during the *** can react with itself or other reactants to form other intermediates,such as 1,3,5-triphenyl-1,3,5-triazinane and 2-（（phenylamino）methyl）phenol,and further form benzoxazine and byproducts.

关键词： aniline phenol formaldehyde itself crude originated react monomer probably claimed

Dopamine Inhibits the Expression of Hepatitis B Virus Surface and e Antigens by Activating the JAK/STAT Pathway and Upregulating Interferon-stimulated Gene 15 Expression

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Journal of Clinical and Translational Hepatology 2024年第5期12卷 443-456页

作者： Xiaoquan Liu Xiuqing Pang Zhiping Wan Jinhua Zhao Zhiliang Gao Hong deng Department of Infectious Diseases Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdongChina Guangdong Key Laboratory of Liver Disease Research Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou GuangdongChina Key Laboratory of Tropical Disease Control(Sun Yat-sen University) Ministry of EducationGuangzhouGuangdongChina

Background and Aims:Hepatitis B virus(HBV)infection is a major risk factor for cirrhosis and liver cancer,and its treatment continues to be *** previously demonstrated that a dopamine analog inhibited the packaging of pregenomic RNA into *** present study aimed to determine the effect of dopamine on the expressions of hepatitis B virus surface and e antigens(HBsAg and HBeAg,respectively)and to elucidate the underlying ***:We used dopamine-treated HBVinfected HepG2.2.15 and NTCP-G2 cells to monitor HBsAg and HBeAg expression *** analyzed interferon-stimulated gene 15(ISG15)expression in dopamine-treated *** knocked down ISG15 and then monitored HBsAg and HBeAg expression *** analyzed the expression of Janus kinase(JAK)/signal transducer and activator of transcription(STAT)pathway factors in dopamine-treated *** used dopamine hydrochloride-treated adeno-associated virus/HBV-infected mouse model to evaluate HBV DNA,HBsAg,and HBeAg *** virus was collected from HepAD38.7 cell culture ***:Dopamine inhibited HBsAg and HBeAg expression and upregulated ISG15 expression in HepG2.2.15 and HepG2-NTCP cell ***15 knockdown increased HBsAg and HBeAg expression in HepG2.2.15 ***-treated cells activated the JAK/STAT pathway,which upregulated ISG15 *** the adeno-associated virus-HBV murine infection model,dopamine downregulated HBsAg and HBeAg expression and activated the JAK-STAT/ISG15 ***:Dopamine inhibits the expression of HBsAg and HBeAg by activating the JAK/STAT pathway and upregulating ISG15 expression.

关键词： Hepatitis B virus Dopamine JAK-STAT/ISG15 axis HBV surface antigen HBV e antigen HepG2.2.15 cell line Human NTCP-expressing HepG2 cell line HepAD38 cell line

The effects of water depth on the growth and reproduction of Potamogeton crispus in an in situ experiment

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Journal of Plant Ecology 2017年第3期10卷 546-558页

作者： Nannan Zhou Weiping Hu Jiancai deng Jinge Zhu Weiwei Xu Xin Liu State Key Laboratory of Lake Science and Environment Nanjing Institute of Geography and LimnologyChinese Academy of Sciences73 East Beijing RoadNanjing 210008JiangsuChina College of Environmental Science and Engineering Anhui Normal University189 South Jiuhua RoadWuhu 241000AnhuiChina University of the Chinese Academy of Sciences 19 Yuquan RoadBeijing 100049China

Aims Water level is one of the most important determinants of the distri-bution and composition of submersed aquatic vegetation in shal-low *** changes in nutrient loading,large-scale declines in submerged macrophytes in shallow lakes are largely attributed to strong external or internal forces,including changes in water *** a winter-active submerged macrophyte,Potamogeton crispus has important functions in aquatic *** objec-tives of our study were to reveal the effects of water depths on the germination,growth,reproduction and morphological changes of *** under natural environmental conditions;identify the optimum water depth range for colonization of ***;and pre-dict the succession course for *** in Lake *** A long-term in situ experiment was performed to study the effects of water depth on the growth and morphology of *** across the entire life *** were grown in the improved cross type of rhizotrons for 30 weeks at three different water depths(60,120 and 200 cm)in Dongtaihu Bay of Lake *** measured the plant height,root length,the length and width of leaves and counted the numbers of leaves,ramets,turion spikes and roots of each plant on each observation day during the *** Findings Water depths ranging from 60 to 120 cm were favourable for above-ground vegetation growth,root tissue growth and the reproductive ability of *** water depth of 200 cm or beyond,the distri-bution of *** will be limited in the following year because of the lack of turion formation and the severe inhibition of ramet *** relationship between above-ground biomass and growth time at three different water depths fits a logistic growth curve well(Ple for growth of other submerged *** a continuous water depth of~60-120 cm is the op

关键词： influence strength morphology responses rhizotron shallow lakes submerged plant

Design of superior electrostriction in BaTiO_(3) -based lead-free relaxors via the formation of polarization nanoclusters

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InfoMat 2023年第1期5卷 114-124页

作者： Lu Wang He Qi Shiqing deng Lingzhi Cao Hui Liu Shuxian Hu Jun Chen Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijingPeople's Republic of China Department of Physical Chemistry University of Science and Technology BeijingBeijingPeople's Republic of China School of Mathematics and Physics University of Science and Technology BeijingBeijingPeople's Republic of China

Electrostrictive materials have wide applications in modern high-precision electronic *** by growing environmental concerns,there is demand for lead-free materials with superior electrostriction *** this study,we demonstrate a record-high electrostrictive coefficient of~0.0712 m^(4) C^(-2) in perovskite ferroelectric ceramics,along with hysteresis-free strain as well as excellent frequency and thermal stabilities,in lead-free BaTiO_(3)-based ceramics through a polarization nanocluster *** appro-priately introducing Li+and Bi^(3+)into the BaTiO 3 lattice matrix,the long-range ferroelectric ordering can be broken,and polarization nanoclusters can be formed,resulting in a relaxor state with concurrently suppressed polariza-tion and maintained electro-strain.A three-dimensional atomic model constructed using advanced neutron total-scattering data combined with the reverse Monte Carlo method indicates the existence of Bi and Li segregations at the subnanometer scale,which confirms the prediction made by density functional theory *** a short-range chemical order destroys the long-range ferroelectric order of the off-centered Ti polar displacements and leads to the embedding of Li+/Bi ^(3+)-rich polar nanoregions in the Ba^(2+)-rich polarization disorder ***,a completely reversible electric-field-induced lattice strain is observed,giving rise to pure electrostriction without hysteresis *** work provides a novel strategy for developing lead-free relaxor ferroelectrics with high electrostriction performance.

关键词： BaTiO_(3) electrostrictive effect local structure relaxor ferroelectrics

Characterization of SARS-CoV-2-specific humoral immunity and its potential applications and therapeutic prospects

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Cellular & Molecular Immunology 2022年第2期19卷 150-157页

作者： Jiaxin Zheng Yingying deng Zhenyu Zhao Binli Mao Mengji Lu Yong Lin Ailong Huang Key Laboratory of Molecular Biology of Infectious Diseases(Chinese Ministry of Education) Institute for Viral HepatitisDepartment of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqingChina. Institute for Virology University Hospital EssenUniversity of Duisburg-EssenEssen 45122Germany

Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is an ongoing pandemic that poses a great threat to human health *** the humoral immune response plays essential roles in disease occurrence and development,understanding the dynamics and characteristics of virus-specific humoral immunity in SARS-CoV-2-infected patients is of great importance for controlling this *** this review,we summarize the characteristics of the humoral immune response after SARS-CoV-2 infection and further emphasize the potential applications and therapeutic prospects of SARSCoV-2-specific humoral immunity and the critical role of this immunity in vaccine ***,serological antibody testing based on the humoral immune response can guide public health measures and control strategies;however,it is not recommended for population surveys in areas with very low *** evidence suggests that asymptomatic individuals have a weaker immune response to SARS-CoV-2 infection,whereas SARS-CoV-2-infected children have a more effective humoral immune response than *** correlations between antibody(especially neutralizing antibody)titers and protection against SARS-CoV-2 reinfection should be further *** addition,the emergence of cross-reactions among different coronavirus antigens in the development of screening technology and the risk of antibody-dependent enhancement related to SARS-CoV-2 vaccination should be given further attention.

关键词： Antibody Humoral immunity SARS-CoV-2 Serological antibody test Vaccine

Fabric Defect Detection Using Independent Component Analysis and Phase Congruency

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Wuhan University Journal of Natural Sciences 2014年第4期19卷 328-334页

作者： leNG Qiujun ZHANG Hu FAN Cien deng Dexiang School of Electronic Information Wuhan University

A novel method based on independent component analysis and phase congruency is proposed for detecting defects in textile fabric images. By independent component, we can obtain textile structural features of fabric-free images. By phase congru- ency, structure information is reduced, which can distinguish the defect region from the defect-free regions. Finally, we have the detecting result from binary image which is obtained by a thresh- old step, Compared with other algorithms, the proposed method not only has robustness with high detection rate, but also detects various types of defects quite well.

关键词： fabric defect detection independent componentanalysis phase congruency morphological filter

Velocity distribution of the flow field in the cyclonic zone of cyclone-static micro-bubble flotation column

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International Journal of Mining Science and Technology 2013年第1期23卷 89-94页

作者： deng Xiao-wei Liu Jiong-tian Wang Yong-tian Cao Yi-jun School of Chemical Engineering and Technology China University of Mining & Technology

Laboratory experiments have been conducted to study the flow field in a cyclone static micro-bubble flotation column. The method of Particle Image Velocimetry (PIV) was used. The flow field velocity distribution in both cross section and longitudinal section within cyclonic zone was studied for different circulating volumes. The cross sectional vortex was also analyzed. The results show that in cross section as the circulating volume increases from 0.187 to 0.350 m 3 /h, the flow velocity ranges from 0 to 0.68 m/s. The flow field is mainly a non-vortex potential flow that forms a free vortex without outside energy input. In the cyclonic region the vortex deviates from the center of the flotation column because a single tangential opening introduces circulating fluid into the column. The tangential component of the velocity plays a defining role in the cross section. In the longitudinal section the velocity ranges from 0 to 0.08 m/s. The flow velocity increases as does the circulating volume. Advantageous mineral separation conditions arise from the combined effects of cyclonic flow in cross and longitudinal section.

关键词： Cyclone-static micro-bubble flotation column PIV Cyclonic flow field Velocity distribution

A Simple Implementation of Distributed Vertical Search and Information Integration Technology

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Wuhan University Journal of Natural Sciences 2013年第6期18卷 511-516页

作者： LIU Jinshuo YANG Nanhai LIU Yuan deng Juan School of Computer Wuhan University International School of Software Wuhan University

The paper proposes the research on the distributed vertical search and information integration technology based on Web mining, which aims at satisfying the requirements of the spe- cific fields＇ applications. Nowadays, mining, analyzing, and inte- grating Web＇s content have become an important trend for daily use. The technique includes the Map/Reduce model, the depth search, and the basic principles of information integration. The focus of the paper is how to implement the distributed vertical search engine based on Map/Reduce technology and the informa- tion integration system. System optimization mechanism and the system test are also proposed.

关键词： distributed system search engine Hadoop Map/Reduce

Effects of Co-60 gamma-irradiation and refrigerated storage on the quality of Shatang mandarin

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Food Science and Human Wellness 2014年第1期3卷 9-15页

作者： Ke Zhang Yueye deng Haohao Fu Qunfang Weng Key Laboratory of Pesticide and Chemical Biology Ministry of EducationGuangzhou 510642PR China

The effectiveness of Co-60 gamma irradiation in controlling citrus red mite(Panonychus citri McGregor)had been proved in our earlier ***,whether it could be used as an alternative method to replace the current way of quarantine treatment against citrus red mites depends on the performances of effective doses on citrus *** study was conducted to explore the effects of Co-60 gamma irradiation on the nutrient composition of citrus(Shatang mandarin);selected fruits were divided into different groups and each group was irradiated at 0.0,0.2,0.3,0.4,0.5,and 0.6,*** then the treated fruits were stored at 4◦C and the nutrient composition was studied in the following *** results showed that the shelf-life could be extended when fruits were irradiated in the dose range of 0.2–0.4 kGy,while most unirradiated citrus decayed by 15 *** also turned out that the citrus irradiated at 0.5 and 0.6 kGy were fully decayed within 45 d of refrigerated *** content of total soluble solids(TSS),total sugar,ascorbic acid(AA),and titratable acidity had no significant differences compare to those of the control during the 15 d storage ***,the activities of peroxidase(POD)and superoxide dismutase(SOD)decreased after 15 d;the improvement of storage quality and shelf life may be explained by the change of the protective enzyme *** conclusion,the results of citrus fruit treated with irradiation at a certain dose indicated the potential use of Co-60 gamma irradiation as a safe quarantine treatment.©2014 Beijing Academy of Food *** and hosting by Elsevier *** rights reserved.

关键词： Shatang mandarin Irradiation Cold storage Nutrient composition

Synthesis and Characterization of Osmium Polycyclic Aromatic Complexes via Nucleophilic Reactions of Osmapentalyne

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Chinese Journal of Chemistry 2017年第5期35卷 628-634页

作者： Qin Zhu Congqing Zhu Zhihong deng Guomei He Jiangxi Chen Jun Zhu Haiping Xia State Key Laboratory of Physical Chemistry of Solid Surfaces and Collaborative Innovation Center of Chemistry for Energy Materials ( iChEM) and Department of Chemistry College of Chemistry and Chemical Engineering Xiamen University Xiamen Fujian 361005 China Department of Materials Science and Engineering College of Materials Xiamen University Xiamen Fujian 361005 China

Treatment of osmapentalyne [Os { ≡C-C（COOMe）=CH-C =CH-C（PPh3） =CH-}Cl（PPh3）2]＋ BF4-with arylamines in the presence of Cs2CO3 produced osmium-bridged polycyclic aromatic *** this reaction,metal carbyne of osmapentalyne was first attacked by nucleophiles,followed by a C-H oxidative *** UV-Vis spectra of these osmium-bridged polycyclic aromatic complexes were *** result shows that these osmium-bridged polycyclic aromatic complexes have broad absorption in the UV-Vis region up to 650 nm.

关键词： metallapentalyne carbyne aromaticity nucleophilic C--H activation