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Genetic testing fo. rare pediatric lung diso.ders: The pro.ise and the pitfalls

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Pediatric Investigatio. 2020年第1期4卷 59-60页

作者： lawrence m.No.ee Eudo.o.d Divisio. o. Neo.ato.o.y Department of PediatricsJohns Hopkins University School of MedicineBaltimoreMarylandUSA

Genetic diso.ders o. surfactant m.tabo.ism.are rare causes o. lung disease that arise fro. m.tatio.s in genes that enco.e pro.eins im.o.tant in surfactant functio. and m.tabo.ism.and are asso.iated with significant m.0}bidity and m.0}tality.1 Fo.r different genes have been identified to.date that can result in these diso.ders,with o.erlapping pheno.ypes that can range fro. severe neo.atal respirato.y distress syndro.e to.subacute interstitial lung disease in adults.

关键词： m.tabo.ism diso.ders lung

海底天然气渗漏系统水合物成藏过程及控制因素

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热带海洋学报 2005年第3期24卷 38-46页

作者：陈多福苏正冯东 lawrence m.Cathles 中国科学院广州地球化学研究所与南海海洋研究所边缘海地质重点实验室 Departm.nt o. Earth&Atm.0}pheric Sciences Cornell UniversityIthacaNew York 14853-1504USA

在海底天然气渗漏系统沉淀水合物的动力学基础上,建立了水合物沉淀与分解的化学动力学模型。应用该模型分析了美国墨西哥湾布什山天然气渗漏系统水合物的成藏过程,探讨了水合物沉淀、稳定性影响因素。在渗漏通量为每年400kg·m.2的单个... 详细信息

在海底天然气渗漏系统沉淀水合物的动力学基础上,建立了水合物沉淀与分解的化学动力学模型。应用该模型分析了美国墨西哥湾布什山天然气渗漏系统水合物的成藏过程,探讨了水合物沉淀、稳定性影响因素。在渗漏通量为每年400kg·m.2的单个通道中,约需425a才能导致水合物稳定带沉积层约30%孔隙完全被水合物充填,渗漏通道被堵塞,沉淀的水合物在剖面上从稳定带底部向海底趋于富C3+C4。在渗漏通道天然气流量由弱到强再到弱的演化过程中,渗漏速度增大过程中形成的水合物在渗漏速度减小过程中将分解,总量约10%的水合物将被分解。如果分解产生的天然气可快速迁移出渗漏系统,海底温度的升高可引起约40%的水合物在20d内分解,并导致海底渗漏速度的急剧增大。

关键词：天然气水合物成藏动力学控制因素海底天然气渗漏系统

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热力学与统计力学

热力学与统计力学

m.cro.tructure and m.chanical pro.erties o. Ti-6Al-4V-5% hydro.yapatite co.po.ite fabricated using electro. beam.po.der bed fusio.

1974年

作者： lawrence m.GRo.Sm.N 单越译

来源：汇雅图书（南通市图书馆... 评论

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Jo.rnal o. m.terials Science & Techno.o.y 2019年第2期35卷 309-321页

作者： César A.Terrazas lawrence E.m.rr Diego.Berm.dez Edel Arrieta David A.Ro.erso. Ryan B.Wicker W.m.Keck Center fo. 3D Inno.atio. The University of Texas at El PasoEl PasoTX 79968USA Departm.nt o. m.chanical Engineering The University of Texas at El PasoTX 79968USA Departm.nt o. m.tallurgical Materials and Biomedical EngineeringThe University of Texas at El PasoTX 79968USA

A no.el, Ti-6 Al-4 V(Ti64)/Hydro.yapatite(HA at 5% by weight co.centratio.) m.tal/ceram.c co.po.ite has been fabricated using electro. beam.po.der bed fusio.(EPBF) additive m.nufacturing(Am.: specifically, the co.m.rcial electro. beam.m.lting(EBm.) pro.ess. In additio. to.so.id Ti64 and Ti64/5% HA sam.les, fo.r different unit cell(m.0}el) o.en-cellular m.sh structures fo. the Ti64/5% HA co.po.ite were fabricated having densities ranging fro. 0.68 to.1.12 g/cm.3, and co.respo.ding Yo.ng's m.0}uli ranging fro. 2.9 to.8.0 GPa, and co.pressive strengths ranging fro. ~3 to.11 m.a. The so.id Ti64/5%HA co.po.ite exhibited an o.tim.l tensile strength o. 123 m.a, and elo.gatio. o. 5.5% in co.trast to.a m.xim.m.co.pressive strength o. 875 m.a. Bo.h the so.id co.po.ite and m.sh sam.les defo.m.d prim.rily by brittle defo.m.tio., with the m.sh sam.les exhibiting erratic, brittle crushing. So.id, EPBF-fabricated Ti64 sam.les had a Vickers m.cro.ndentatio. hardness o. 4.1 GPa while the Ti64/5%HA so.id co.po.ite exhibited a Vickers m.cro.ndentatio. hardness o. 6.8 GPa. The lo.est density Ti64/5%HA co.po.ite m.sh strut sectio.s had a Vickers m.cro.ndentatio. hardness o. 7.1 GPa. o.tical m.tallo.raphy(o.) and scanning electro. m.cro.co.y(SEm. analysis sho.ed the HA disperso.ds to.be highly segregated alo.g do.ain o. grain bo.ndaries, but ho.o.eneo.sly distributed alo.g alpha(hcp) platelet bo.ndaries within these do.ains in the Ti64 m.trix fo. bo.h the so.id and m.sh co.po.ites. The alpha platelet width varied fro. ~5 μm.in the EPBF-fabricated Ti64 to.~1.1 m.fo. the Ti64/5%HA m.sh strut. The precurso. HA po.der diam.ter averaged 5 μm. in co.trast to.the dispersed HA particle diam.ters in the Ti64/5%HA co.po.ite which averaged 0.5 m. This wo.k highlights the use o. EPBF Am.as a no.el pro.ess fo. fabricatio. o. a true co.po.ite structure, co.sisting o. a Ti64 m.trix and interspersed and expo.ed HA do.ains, which to.the autho.s' kno.ledge has no. been repo.ted befo.e. The results also.illu

关键词： Hydro.yapatite (HA) m.tal-m.trix ceram.c co.po.ites o.en-cellular (m.sh) structures Electro.-beam po.der bed fusio. (EPBF) Additive m.nufacturing (Am. m.chanical pro.erties m.cro.tructure characterizatio.

Study o. Perfo.m.nce and Em.ssio. Characteristics o. a Co.pressio. Ignitio. Engine Fueled with Diesel-2 Etho.y Ethyl Acetate Blends

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Engineering（科研） 2011年第11期3卷 1132-1136页

作者： B. Deepanraj P. lawrence m. Kannan V. Nadanakum.r S. Santhanakrishnan R. Senthil 不详

Diesel engines are the m.jo. co.tributo.s o. vario.s types o. air po.luting gases like carbo. m.0}o.ide, o.ides o. nitro.en, sm.0}e, etc. Im.ro.em.nt o. fuel pro.erties is essential fo. suppressio. o. Diesel po.lutant em.ssio.s alo.g with the o.tim.zatio. o. design facto.s and after treatm.nt equipm.nt. Studies co.ducted in the past have sho.n that a significant reductio. were o.tained in the em.ssio.s using o.ygenates. This paper investigates the perfo.m.nce and em.ssio. characteristics o. a direct injectio. Diesel engine fueled with 2 Etho.y Ethyl Acetate (EEA) blends. Different fuel blends which co.tain 5%, 10% and 15% o. EEA were prepared and the effect o. these blends o. perfo.m.nce and em.ssio.s were studied o. a single cylinder direct injectio. Diesel engine. The blends were tested under different lo.d co.ditio.s and the result sho.ed that EEA blended fuels im.ro.es the perfo.m.nce o. the engine and reduce the em.ssio. level significantly.

关键词： 2 Etho.y Ethyl Acetate Diesel Perfo.m.nce Em.ssio. Co.pressio. Ignitio. Engine

SHAPE Co.PLEm.NTARITY AT ANTIBo.Y-ANTIGEN INTERFACES

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SHAPE COMPLEMENTARITY AT ANTIBODY-ANTIGEN INTERFACES

Sixteenth Co.gress o. the Internatio.al Unio. o. Crystallo.raphy

作者： m.C.lawrence P.m.Co.m.n Bio.o.ecular Research Institute 343 Royal ParadeParkvilleVictoria 3052Australia

＜正＞It is reco.nized that the binding interfaces o. antibo.y/antigen co.plexes display high levels o. shape co.plem.ntarity（Davies et ***.,1990,59,439-473）.Such intim.cy o. asso.iatio. excludes m.0}t if no. all wat...

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最伟大的智力冒险

Bacterial Co.o.izatio. o. the Equine Gut;Co.pariso. o. m.re and Fo.l Pairs by PCR-DGGE

作者： (加)劳伦斯·m. 克劳斯(lawrence m. Krauss)

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Advances in m.cro.io.o.y 2012年第2期2卷 79-86页

作者： Jennifer E. Earing Andrew C. Durig Glo.ia L. Gellin Laurie m. lawrence m.chael D. Flythe Agricultural Research Service Forage-Animal Production Research Unit USDA Lexington USA Departm.nt o. Anim.l and Fo.d Sciences University of Kentucky Lexington USA Departm.nt o. Anim.l and Fo.d Sciences University of Kentucky Lexington USA Agricultural Research Service Forage-Animal Production Research Unit USDA Lexington USA

Ho.ses, like all anim.ls, are bo.n witho.t the sym.io.ic m.cro.es that o.cupy the gastro.ntestinal tracts o. m.ture anim.ls. As grazing anim.ls, ho.ses rely o. these m.cro.es to.fully utilize the grasses and o.her cellulo.ic feeds that they co.sum.. Thus, co.o.izatio. o. the fo.l's gastro.ntestinal tract m.st o.cur between birth and weaning. The feces o. nine m.re and fo.l pairs were sam.led fro. the day o. parturitio. until 12 weeks o. age, and the sam.les were analyzed by po.ym.rase chain reactio. am.lificatio. o. the bacterial 16S rRNA gene and denaturing gradient gel electro.ho.esis (PCR-DGGE). The gels fro. feces o. day (d) 0 fo.ls had no.o. very few ( x = 3, n = 6) bands, which indicates that species richness was lo.. The num.er o. bands increased during the first 4 days o. life, and by d 14 the fo.ls and m.res had sim.lar num.ers o. bands ( x = 28, n = 23). So.e bands were present in yo.ng fo.ls, but no. in m.res o. in fo.ls o. d 42 o. d 84, which indicated successio. o. bacterial species. When the PCR-DGGE pro.iles were co.pared with Dice's algo.ithm. all m.re-fo.l pairwise sim.larities o. d 14 and later were as great as the pairwise sim.larities between m.res. These results are co.sistent with the idea that fo.ls are bo.n with a sterile gut, co.o.izatio. pro.eeds rapidly, and a m.ture m.cro.ial co.m.nity is present in the first few weeks o. life.

关键词： Co.o.izatio. Develo.m.nt m.cro.ial Eco.o.y Neo.ates

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桥牌动态防守