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现代装饰（家居） 2011年第4期 24-30页

作者： martyn lawrence-Bullard 肖俊 martyn lawrence-Bullard Design创始人

项目地址美国加利福尼亚州项目面积300m^2设计单位martyn lawrence-Bullard Design超模Cheryl Tiegs的住宅坐落在群山之间,由martyn lawrence-B ullard为其设计。不可否认,Cheryl作为20世纪70年代的偶像,她的模特职业生涯让她从中西部... 详细信息

项目地址美国加利福尼亚州项目面积300m^2设计单位martyn lawrence-Bullard Design超模Cheryl Tiegs的住宅坐落在群山之间,由martyn lawrence-B ullard为其设计。不可否认,Cheryl作为20世纪70年代的偶像,她的模特职业生涯让她从中西部的谦逊开始蜕变成一位羽翼丰满的超级明星。17岁时。

关键词：项目地址项目面积超级明星住宅空间时尚杂志加利福尼亚州设计单位 lawrence 巴厘体

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髋关节成形术：微创技术与计算机导航暂无

丛书名：世界经典医学名著译丛

2008年

作者：（美）lawrence D. Dorr原唐农轩范清宇主译

随着关节置换的广泛应用，髋关节成形术已成为一种常用的重要手术。虽然是假体植入，但对无法挽救的髋关节病患者而言，可以解除疼痛、纠正畸形、改善活动，因此该手术具有很强的实际意义。由于髋部解剖结构有一定的复杂性，关节置换更... 详细信息

ISBN: (纸本)7506290340

随着关节置换的广泛应用，髋关节成形术已成为一种常用的重要手术。虽然是假体植入，但对无法挽救的髋关节病患者而言，可以解除疼痛、纠正畸形、改善活动，因此该手术具有很强的实际意义。由于髋部解剖结构有一定的复杂性，关节置换更涉及力学、材料、设计、器械、操作技术、适应证选择等，因此如何掌握好手术原则、减少损伤、精确地植入相关组件使其既获得符合力学要求的位置又固定牢固，骨科医师应对此深入学习研究、熟练掌握，以求获得最佳疗效。 Dorr博士主编的本书对上述问题进行了详细叙述。作为世界著名的髋外科专家，Dorr博士临床经验丰富、学识渊博，特别是有自身经历手术的切身体会，使本书更加具有可读性。本书内容包括首次和翻修手术、微创技术和计算机导航。既全面又细致入微，有理论、有技术，更富有艺术性。文字简练，章节组织有序，手术步骤解释准确，涉及临床问题的方方面面，并附实例可以更好地指导实践。本书附有DVD影像资料，可反复演示手术关键程序，便于读者学习观摩。

关键词：医药、卫生外科学骨科学(运动系疾病、矫形外科学)

来源：畅想之星图书光盘版（南... 评论

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热带气旋运动的动力—统计预报业务试验

气象科技 1979年第S1期 1-5页

作者： C.J.Neumann m.B.lawrence 殷显曦

一、引言近年来,许多热带气旋具有运动异常的性质,从而暴露了纯统计系统所固有的弱点,并促进了动力和统计—动力模式的发展。因此,miller(1972)等用一种七层模式进行试验,而Neumann和lawrence(1973)介绍了一种统计—动力模式,即NHC73,... 详细信息

一、引言近年来,许多热带气旋具有运动异常的性质,从而暴露了纯统计系统所固有的弱点,并促进了动力和统计—动力模式的发展。因此,miller(1972)等用一种七层模式进行试验,而Neumann和lawrence(1973)介绍了一种统计—动力模式,即NHC73,它采用美国气象中心的原始方程模式的输出作为统计预报系统的输入。1973年和1974年飓风季节,用NHC73的两种方案在业务预报中作了试验。本文评论了NHC73的发展,介绍了两年中的试验结果,以及提出了将统计、动力概念用于热带气旋预报的发展途径。二、数值预报资料的统计应用 Klein和 Glahn(1974)介绍了两种已成功地将数值预报资料引入统计预报结构的方法。其一是所谓“完全预报”法,另一种称模式输出统计法,简称

关键词：完全预报法热带气旋协方差矩阵预报因子预报因素方差缩减统计预报

Selection of Reference Genes in Equine White Blood Cells for Real Time PCR Normalization Following Extracorporeal Shock Wave Therapy

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American Journal of molecular Biology 2014年第2期4卷 72-80页

作者： Zibin Jiang Jinwen Chen Cornelius E. Uboh mary A. Robinson lawrence R. Soma Department of Clinical Studies New Bolton Center Campus University of Pennsylvania School of Veterinary Medicine Philadelphia USA Department of Clinical Studies New Bolton Center Campus University of Pennsylvania School of Veterinary Medicine Philadelphia USA Pennsylvania Equine Toxicology & Research Center Department of Chemistry West Chester University West Chester USA

Selection of proper reference genes (RGs) is an essential step needed for accurate normalization of results from genomic studies. Expression of RGs is regulated by many factors such as species, age, gender, type of tissue, the presence of disease, and the administration of therapeutic treatment. The aim of the present study was to identify optimal RGs in a set of blood samples collected at different time points (0, 24, 48, 72 h) from horses following administration of extracorporeal shock wave therapy (ESWT). The mRNA expression of twelve RGs: HPRT1, ACTB, HSP90A, SDHA, GUSB, B2m, UBC, NONO, TBP, H6PD, RPL32, GAPDH was determined using real time quantitative polymerase chain reaction (qPCR). An SAS program developed on the algorithm of geNorm, SASqPCR, was used to determine stability of the expression and the number of optimal RGs. The results showed that the range of quantification cycle (Cq) values of the evaluated genes varied between 17 and 26 cycles, and that one optimal RG, ACTB, was sufficient for normalization of gene expression. Results of stability of expression demonstrated that ACTB was the optimal choice for all the samples studied. Notably, in samples collected at 72 h post ESWT, TBP showed a significant change in the expression level, and was not suitable for use as a RG. These results substantiate the importance of validating and selecting an appropriate RG.

关键词： Reference Genes Real Time PCR Normalization Equine White Blood Cell Extracorporeal Shock Wave Therapy

Fenton-Like Oxidation of Acid Yellow 23 in the Presence of Iron Rich Soil

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Advances in Chemical Engineering and Science 2016年第5期6卷 553-569页

作者： Tagne Guy merlain lawrence Tatanah Nanganoa Belibi Belibi Placide Desire Ndi Julius Nsami Ketcha Joseph mbadcam Applied Physical and Theoretical Chemistry Laboratory Department of Inorganic Chemistry University of Yaoundé Yaoundé Cameroon Soil Plant and Water Analysis Laboratory Department of Soil water and Atmosphere Institute of Agricultural Research for Development (IRAD) Buea Cameroon

Treatment of yellow dye 23 by heterogeneous Fenton-like process was studied using iron rich soil as an iron source. The iron rich soil sample was characterized by XRD, SEm and BET analysis. XRD pattern indicates that the iron rich soil is made of goethite and hematite. The reaction was systematically investigated under various experimental conditions such as pH, iron rich soil dosage, oxidant and dye concentrations. The result revealed that using iron rich soil as catalyst led to high discoloration efficiency (97.71% for 140 min of treatment) at pH = 2.5, 2 g/L iron rich soil and 16 m·mol/L H2O2. The degradation kinetics of acid yellow 23 can be described by a pseudo-first-order reaction following the Langmuir-Hinshelwood mechanism. The main roles of hydroxyl radicals in degradation process were investigated by adding of various radical scavengers.

关键词： Acid Yellow 23 Discoloration Heterogeneous Fenton Iron Rich Soil

S2B-2 Comorbidity of Anxiety and Depression Induced by Liang’s Contextual-Stress Box in mice

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神经药理学报 2018年第4期8卷 44-45页

作者： LIANG Jian-hui LIANG hui CHENG tao LIU Xiao-yan Simon m.Y.Lee TANG Ben-qin WANG Xiufen CHEN Feng Andrew J.lawrence Department of molecular and Cellular Pharmacology School of Pharmaceutical SciencesPeking UniversityBeijing100083China Department of Pharmacology School of Basic Medicine SciencesPeking UniversityBeijing100083China State Key Laboratory of Quality Research in Chinese medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacaoChina The Florey Institute of Neuroscience and mental Health University of MelbourneParkvilleVictoria3010Australia

Rationale:Comorbidity of depression and anxiety is one of the most common mental disorders in *** experimental procedures,however,have focused on identifying mixed depression-and anxiety-like behaviors in animal ***:To develop a novel testing paradigm,the so-called Liang’s contextual-stress Box(briefly,Liang’s Box),for evaluating depression-and/or anxiety-like behaviors in ***:Liang’s Box consisted of a central area(CA)with three peripheral arms(PA).mice were placed individually in the end of a peripheral arm facing to the central area and were allowed to travel around Liang’s *** a test period,behavioral parameters were recorded and collected by a video-tracking system named SmART 3.0(Panlab,Spain),including①Latency to CA,②Time spent in CA(CA-time),③Distance traveled in CA(CA-distance),④Distance traveled in PA(PA-distance),⑤Transition number between CA and PA,⑥Global activity,⑦CA-time/cm2,⑧PA-time/cm2,⑨CAdistance/cm2,and⑩PA-distance/*** order to assess the reliability and validity of Liang’s Box and get baseline information,we undertook a series of experiment,including verifying consistency and stability in the various strains of mice(Km,ICR,and C57 BL/6 J mice),imposing high illumination,restraint and tail suspension stress,pre-treating with an anxiolytic(diazepam,buspirone)or antidepressant(desipramine,mianserin).Results:①There were not remarkable differences in all the parameters among Km,ICR,and C57 BL/6 J mice;②High illumination,restraint and tail suspension significantly increased the latency to CA and decreased the CA-time,CA-distance and transition ***,these three types of stresses evoked different effect on global *** illumination increased activity,but restraint stress had no significant *** contrast with high illumination,tail suspension stress markedly reduced activity in mice;③The anxiolytics diazepam(0.25 mg·kg-1 and 0.5 mg·kg-1,i.p.)and buspirone(0.5 mg·kg-1 and 1.0 mg·kg-1,i.p.)

关键词： Depression Anxiety Stress Animal model Comorbidity

辽河三角洲翅碱蓬湿地不同植被覆盖度下的土壤对碳的扣留

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中国地质 2014年第2期41卷 648-657页

作者：余雪洋叶思源 Nicholas lawrence Yuknis Edward A.Laws 赵广明袁红明丁喜桂王锦青岛大学山东青岛266071 国土资源部海洋油气资源与环境地质重点实验室山东青岛266071 青岛海洋地质研究所山东青岛266071 路易斯安那州立大学

为研究辽河三角洲湿地的固碳能力,2010年5月在辽河三角洲双台子河口东侧的两个翅碱蓬湿地区域采取7个柱状样,通过对样品的化学分析测试,并利用210Pb测年法确定的沉积速率研究了土壤对碳的扣留速率,其结果表明：有机碳浓度分别与各营养... 详细信息

为研究辽河三角洲湿地的固碳能力,2010年5月在辽河三角洲双台子河口东侧的两个翅碱蓬湿地区域采取7个柱状样,通过对样品的化学分析测试,并利用210Pb测年法确定的沉积速率研究了土壤对碳的扣留速率,其结果表明：有机碳浓度分别与各营养元素浓度间有显著的正相关关系（p＜0.01）,指示沉积物中的有机物质对营养元素有很强的富集能力,同时营养元素促进植物的生长,从而影响土壤碳的加积速率.研究区总碳浓度范围为10.5～14.6 g/kg,其中约83％为有机碳,其相应的土壤对总碳和有机碳扣留速率分别为98.02～260.37 g/m2/a（均值171.84 g/m2/a）和81.17～229.98 g/m2/a（均值141.29 g/m2/a）.本研究区,土壤对碳的扣留速率主要受土壤的沉积速率控制,并与高程有显著的相关关系（p＜0.01）.土壤对碳扣留机制的研究有助于加深对全球碳循的理解.

关键词：辽河三角洲湿地碳扣留营养成分 210Pb测年

Nanoparticles for targeted cancer radiotherapy

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Nano Research 2020年第11期13卷 2887-2897页

作者： Roger m.Pallares Rebecca J.Abergel Chemical Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCA94720USA Department of Nuclear Engineering University of CaliforniaBerkeleyCA94720USA

Radiotherapy,where ionizing radiation is locally delivered either through an external beam or by surgically implanting radionuclide-based seeds in the tumor,is one of the gold standard treatments for *** to the non-selective nature of radiation,healthy tissue surrounding the cancerous region is usually affected by the ***,new strategies,including targeted alpha therapy,are being studied to improve the selectivity of the treatment and minimize side *** challenges,however,limit the current development of targeted radiotherapy,such as the functionalization of the therapeutic agent with targeting vectors and controlling the release of recoiling *** offer unique opportunities as drug delivery vehicles,since they are biocompatible,enhance the cellular uptake of drugs,and are easily functionalized with targeting *** this review,we examine how nanoparticles can be used for targeted radiotherapy,either as sensitizers of external beams or as delivery vehicles for therapeutic *** describe the clinical relevance of different types of nanoparticles,followed by an analysis of how these nanoconstructs can solve some of the main limitations of conventional ***,we critically discuss the current situation of nanoparticle-based radiotherapy in clinical settings and challenges that need to be overcome in the future for further development of the field.

关键词： radiotherapy targeted cancer radiotherapy nanoparticles cancer targeted alpha therapy external beam