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Follow up of serial urea breath test results in patients after consumption of antibiotics for non-gastric infections

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World Journal of Gastroenterology 2002年第4期8卷 703-706页

作者： Wai-Keung Leung lawrence cheung-Tsui Hung carrie Ka-Li Kwok Rupert Wing-Loong Leong Daniel Kwok-Keung Ng Joseph Jao-Yiu Sung Department of Medicine & Therapeutics Prince of Wales Hospitalthe Chinese University of Hong KongShatinHong KongChina Department of Paediatrics Kwong Wah HospitalKowloonHong KongChina

AIM: The widespread use of antibacterial therapy hasbeen suggested to be the cause for the decline in theprevalence of Helicobacter pyloriinfection. This studyexamine the serial changes of urea breath test resultsin a group of hospitalized patients who were givenantibacterial therapy for non-gastric ***: Thirty-five hospitalized patients who weregiven antibacterial therapy for clinical infections,predominantly chest and urinary infections, werestudied. Most (91%) patients were given singleantibiotic of either a penicillin or cephalosporin *** 13c-urea breath tests were performed within 24hours of initiation of antibiotics, at one-week and atsix-week post-therapy. H. pylori infection wasdiagnosed when one or more urea breath tests ***: All 35 patients completed three serial ureabreath tests and 26 (74 %) were H. pylori-positive. Ten(38 %) H. pylori-infected patients had at least onenegative breath test results during the study *** medium delta 13c values were significantly lowerat baseline (8.8) than at one-week (20.3) and six-week(24.5) post-treatment in H. pylori-positive individuals(P=0.022). clearance of H. pyloriat six-week was onlyseen in one patient who had received anti-helicobactertherapy from another ***: Our results suggested that one-third ofH. pylori-infected individuals had transient false-negative urea breath test results during treatment withantibacterial agent. However, clearance of H. pyloriinfection by regular antibiotic consumption is rare.

关键词：抗生素 HP感染连续尿素呼吸试验耐药

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cannabinoids function in defense against chewing herbivores in cannabis sativa L.

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Horticulture Research 2023年第11期10卷 131-140页

作者： George M.Stack Stephen I.Snyder Jacob A.Toth Michael A.Quade Jamie L.crawford John K.McKay John Nicholas Jackowetz Ping Wang Glenn Philippe Julie L.Hansen Virginia M.Moore Jocelyn K.c.Rose lawrence B.Smart Horticulture Section School of Integrative Plant ScienceCornell UniversityCornell AgriTechGenevaNY 14456United States Plant Biology Section School of Integrative Plant ScienceCornell UniversityIthacaNY 14853United States Plant Breeding Section School of Integrative Plant ScienceCornell UniversityIthacaNY 14853United States Department of Agricultural Biology Colorado State UniversityFort CollinsCO 80523United States cirona Labs GenevaNY 14456United States Department of Entomology Cornell UniversityCornell AgriTechGenevaNY 14456United States

In the decades since the first cannabinoids were identified by scientists,research has focused almost exclusively on the function and capacity of cannabinoids asmedicines and intoxicants for humans and other *** little is knownabout the adaptive value of cannabinoid production,though several hypotheses have been proposed including protection from ultraviolet radiation,pathogens,and *** test the prediction that genotypeswith greater concentrations of cannabinoidswill have reduced herbivory,a segregating F2 population of cannabis sativa was leveraged to conduct lab-and field-based bioassays investigating the function of cannabinoids in mediating interactions with chewing *** the field,foliar cannabinoid concentration was inversely correlated with chewing herbivore *** detached leaves,Trichoplusia ni larvae consumed less leaf area and grew less when feeding on leaves with greater concentrations of *** electron and light microscopy were used to characterize variation in glandular trichome ***-free genotypes had trichomes that appeared *** isolate cannabinoids from confounding factors,artificial insect diet was amended with cannabinoids in a range of physiologically relevant *** grew less and had lower rates of survival as cannabinoid concentration *** results support the hypothesis that cannabinoids function in defense against chewing herbivores.

关键词： function founding ultraviolet

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LOW MOLEcULAR WEIGHT PROTAMINES FOR LONG-AcTING INSULIN FORMULATION

LOW MOLECULAR WEIGHT PROTAMINES FOR LONG-ACTING INSULIN FORM...

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40th IUPAc congress

作者： Yekaterina Vaynshteyn lawrence X. Yu Victor c. Yang Jun F. Liang Department of chemistry and chemical Biology Stevens Institute of TechnologyHobokenNJ 07030 Office of Generic Drugs CDERFDARockvilleMD 20850 college of Pharmacy The University of MichiganAnn ArborMI 48109 Department of chemistry and chemical Biology Stevens Institute of TechnologyHobokenNJ 07030

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冰穹c的大气条件:天文含意

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天文学报 2007年第1期48卷 48-53页

作者： J.S.lawrence M.c.B.Ashley M.G.Burton J.W.V.Storey School of Physics University of New South WalesSydneyNSW 2052Australia

在南极洲高原的冰穹c有望发现非凡的天文观测条件,受此鼓舞,许多国际小组协同努力对该地的大气条件作全面的测量．评述对冰穹c的选址现况,讨论过去、现在和计划中的选址仪器,迄今已得到的结果,以及这些结果的天文含意．

关键词：选址地球南极洲高原冰穹c

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孕妇的饮酒动机及对其妊娠的影响 ——基于Sunyani市的调查

孕妇的饮酒动机及对其妊娠的影响 ——...

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作者： lawrence KWAKU DABANKA 江苏大学

学位级别：硕士

目前,人们一直争论着暴露于小剂量,中度到高剂量的酒精的影响。尽管在某些研究中甚至报道了少量会引起不良的妊娠结局和神经行为影响,但其他研究并未发现负面影响。美国,加拿大,澳大利亚,冰岛,法国,挪威和瑞典等许多国家/地区的当局提... 详细信息

目前,人们一直争论着暴露于小剂量,中度到高剂量的酒精的影响。尽管在某些研究中甚至报道了少量会引起不良的妊娠结局和神经行为影响,但其他研究并未发现负面影响。美国,加拿大,澳大利亚,冰岛,法国,挪威和瑞典等许多国家/地区的当局提出的建议中普遍存在怀孕期间饮酒安全水平的证据以及促进怀孕期间完全戒酒的预防原则。在包括加纳在内的许多发展中国家,该领域的研究仍不发达,在加纳,孕妇中的酒精摄入量很高。与此相应,本研究的目的是检验对孕妇饮酒的原因和影响的认识。制定了以下具体研究目标来指导研究:（a）查明孕妇饮酒的原因;（b）研究饮酒因素与孕妇的关系,以及（c）研究Sunyani市饮酒对孕妇的影响。本研究采用描述性调查研究设计,通过简单的随机抽样方法从Sunyani市的孕妇中选择了412名孕妇。问卷是该研究的主要研究工具。该研究采用分层多元线性回归方法来估计结果。该方法包括两个估计步骤。第一步着重于估计控制变量（社会经济因素）,而第二步包括控制变量和自变量（饮酒动机）。研究表明,社交动机（=0.248,p＜0.01）,增强动机（=0.190,p＜0.01）,应对（=0.197,p＜0.01）和顺从动机（=0.143,p＜0.01）驱动酒精在孕妇中使用酒精表明,这些动机越高,Sunyani市孕妇使用酒精的愿望越高。此外,结果表明,饮酒对Sunyani市孕妇的妊娠相关问题具有积极影响。此外,这项研究的结果表明,饮酒的社交动机,应对动机和顺应动机会增加孕妇的妊娠相关问题。这项研究表明,饮酒水平确实可以调解饮酒动机与致命问题（=0.209,p＜0.01）,孕产妇健康问题（=0.078,p＜0.10）和社会问题（=0.201）之间的关系。,p＜0.01)。根据调查结果,研究得出结论,社交,提高,应对和顺从动机是孕妇饮酒的驱动因素。妇女饮酒的水平对孕妇造成致命,孕产和社会问题。同样,较高的饮酒量会使饮酒动机与妊娠相关问题之间的关系恶化。

关键词：饮酒,妊娠相关问题孕妇饮酒动机加纳

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什么材料可以做敷料?

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医疗卫生装备 1983年第1期 31-38页

作者： J.c.lawrence 陈惠孙

创伤敷料具有悠久的历史。公元前1,500—1,600年古埃及的文字上叙述过许多可作为敷料的原材料,其中包括涂有油脂的绷带(Bryan 1930;Ebell,1937),这种敷料被认为是润肤细布(tullegras)的前身,润肤细布就是 Lumiere 在第一次世界大战时介... 详细信息

创伤敷料具有悠久的历史。公元前1,500—1,600年古埃及的文字上叙述过许多可作为敷料的原材料,其中包括涂有油脂的绷带(Bryan 1930;Ebell,1937),这种敷料被认为是润肤细布(tullegras)的前身,润肤细布就是 Lumiere 在第一次世界大战时介绍的那种致密网眼棉纱浸以液体石腊的敷料(Harkins,1942)。此后,使用过许多种织物,包

关键词：敷料抗菌药物实验性小伤口医药卫生材料伤面渗出液

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classical Stoicism and Renaissance Rhetoric Rhetoric Society of china,Hong Kong,July 28,2010

Classical Stoicism and Renaissance Rhetoric Rhetoric Society...

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世界汉语修辞学会第二届年会暨修辞学国际学术研讨会

作者： lawrence D.Green University of Southern california

＜正＞My talk today addresses Stoicism and its impact upon western rhetoric during the European *** subject is historical,but it puts into high relief some methodological questions about the nature of rhetorical study that is global,multi-cultural,and *** as a philosophy began to take shape in Greek society around 200 B.c.E.,and the full flowering of Renaissance rhetoric occurs around 1600 ***’s at least two cultures in space and time,with an

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Effect of histone deacetylase inhibitor sodium butyrate on behavioral sensitization to a single morphine exposure in c57BL/6 mice

Effect of histone deacetylase inhibitor sodium butyrate on b...

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中国药理学会第十次全国学术会议

作者： Andrew J.lawrence Howard Florey Institute and centre for Neuroscience ParkvilleVictoria 3010Australia

Background and purpose More recently behavioral sensitization induced by a single morphine exposure has been considered as behavioral plasticity associated with drug *** histone acetylation mediating chromatin remodeling plays a critical role in the mechanisms underlying some types of behavioral ***-fore, the present study was designed to investigate whether the HDAc inhibitor SB would alter the establishing processes of behavioral sensitization to a single injection of *** approach Appling a single morphine-induced behavioral sensitization model in male c57BL/6 mice,we chose in this study to multiply treat mice with SB in the phases of induction,transfer,and expression of behavioral sensitization and to measure the distance of horizonal locomotor activity.

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Fabrication of open-cellular(porous) titanium alloy implants: osseointegration, vascularization and preliminary human trials

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Science china Materials 2018年第4期61卷 525-536页

作者： Shujun Li Xiaokang Li Wentao Hou Krishna c. Nune R. Devesh K. Misra Victor L. correa-Rodriguez Zheng Guo Yulin Hao Rui Yang lawrence E. Murr Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China Department of Orthopedics Xijing Hospital Fourth Military Medical University Xi＇an 710032 China Department of Metallurgical Materials and Biomedical Engineering The University of Texas at El Paso El Paso TX 79968 USA

In this study we describe the fabrication of a variety of open-cellular titanium alloy（Ti-6 Al-4 V） implants,both reticular mesh and foam structures, using electron beam melting（EBM）. These structures allow for the elimination of stress shielding by adjusting the porosity（or density） to produce an elastic modulus（or stiffness） to match that of both soft（trabecular） and hard（cortical） bone, as well as allowing for bone cell ingrowth, increased cell density, and all-matrix interactions; the latter involving the interplay between bone morphogenetic protein（BMP-2） and osteoblast functions. The early formation and characterization of elementary vascular structures in an aqueous hydrogel matrix are *** results for both animal（sheep） and human trials for a number of EBM-fabricated, and often patient-specific Tialloy implants are also presented and summarized. The results, while preliminary, support the concept and development of successful, porous, engineered ＂living＂ implants.

关键词： porous implant fabrication osseointegration vascularization animal and clinical human trials

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Hepatic decompensation/serious adverse events in post-liver transplantation recipients on sofosbuvir for recurrent hepatitis c virus

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World Journal of Gastroenterology 2016年第9期22卷 2844-2854页

作者： Neal Patel Kian Bichoupan lawrence Ku Rachana Yalamanchili Alyson Harty Donald Gardenier Michel Ng David Motamed Viktoriya Khaitova Nancy Bach charissa chang Priya Grewal Meena Bansal Ritu Agarwal lawrence Liu Gene Im Jennifer Leong Leona Kim-Schluger Joseph Odin Jawad Ahmad Scott Friedman Douglas Dieterich Thomas Schiano Ponni Perumalswami Andrea Branch Division of Liver Diseases Icahn School of Medicine at Mount Sinai Recanati Miller Transplant Institute Icahn School of Medicine at Mount Sinai

AIM: To determine the safety profile of new hepatitis c virus (HcV) treatments in liver transplant (LT) recipients with recurrent HcV ***: Forty-two patients were identified with recurrent HcV infection that underwent LT at least 12 mo prior to initiating treatment with a Sofosbuvir-based regimen during December 2013-June 2014. cases were patients who experienced hepatic decompensation and/or serious adverse events (SAE) during or within one month of completing treatment. controls had no evidence of hepatic decompensation and/or SAE. HIV-infected patients were excluded. cumulative incidence of decompensation/SAE was calculated using the Kaplan Meier method. Exact logistic regression analysis was used to identify factors associated with the composite ***: Median age of the 42 patients was 60 years [Interquartile Range (IQR): 56-65 years], 33% (14/42) were female, 21% (9/42) were Hispanic, and 9% (4/42) were Black. The median time from transplant to treatment initiation was 5.4 years (IQR: 2.1-8.8 years). Thirteen patients experienced one or more episodes of hepatic decompensation and/or SAE. Anemia requiring transfusion, the most common event, occurred in 62% (8/13) patients, while 54% (7/13) decompensated. The cumulative incidence of hepatic decompensation/SAE was 31% (95%cI: 16%-41%). Risk factors for decompensation/SAE included lower pre-treatment hemoglobin (OR = 0.61 per g/dL, 95%cI: 0.40-0.88, P < 0.01), estimated glomerular filtration rate (OR = 0.95 per mL/min per 1.73 m2, 95%cI: 0.90-0.99, P = 0.01), and higher baseline serum total bilirubin (OR = 2.43 per mg/dL, 95%cI: 1.17-8.65, P < 0.01). The sustained virological response rate for the cohort of 42 patients was 45%, while it was 31% for ***: Sofosbuvir/ribavirin will continue to be used in the post-transplant population, including those with HcV genotypes 2 and 3. Management of anemia remains an important clinical challenge.

关键词： Hepatitis c virus Sofosbuvir Ribavirin Anemia Hepatic decompensation Serious adverse event Liver transplant

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