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Photonics Research 2023年第6期11卷 1113-1124页

作者： thomas jÜRSS GESINE GROSCHE SEBASTIAN KOKE Physikalisch-Technische Bundesanstalt 38116 BraunschweigGermany

For improving the performance of optical frequency dissemination and the resolution of its out-of-loop(OOL)characterization,we investigate a compact free-space interferometer design in which a monolithic assembly forms the reference *** interferometer designs are realized,and their environmental sensitivity is analyzed based on the properties of the materials *** elucidate that in these designs the temperature sensitivities of the out-of-loop signal paths are greater than for the reference *** the estimated temperature-variation-induced frequency transfer errors are observed to be the relevant limitation,the out-of-loop characterization signal can be regarded as a trustworthy upper limit of the frequency transfer error to a remote *** demonstrate a fractional frequency transfer uncertainty and OOL characterization resolution of≤2.7×10^(-21)over many measurement *** a value of(0.23±1.07)×10^(-22)the weighted mean offset is significantly below the best reported results so far.

关键词： characterization fractional limit

Mobile Robotic Platform for Contactless Vital Sign Monitoring

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Cyborg and Bionic Systems 2022年第1期2022卷 87-97页

作者： Hen-Wei Huang jack Chen Peter R.Chai Claas Ehmke Philipp Rupp Farah Z.Dadabhoy Annie Feng Canchen Li Akhil j.thomas Marco da Silva Edward W.Boyer Giovanni Traverso Department of Mechanical Engineering Massachusetts Institute of TechnologyUSA The Koch Institute of Integrated Cancer Rssearch Massachusetts Institute of TechnologyUSA Division of Gast roenterology Brigham and Women's HospitalHarvard Medical SchoolUSA Department of Engineering Science University of TorontoCanada Department of Emergency Medicine Brigham and Women's HospitalHarvard Medical SchoolUSA Department of Psychosocial Oncology and Plliative Care Dana Farber Cancer InstituteUSA The Fenway Institute USA Boston Dynamics USA

The COVID-19 pandemic has accelerated methods to faciltate contactless evaluation of patients in hospital *** minimizing in-person contact with individuals who may have COVID 19,healthcare workers can prevent disease transmission and conserve personal protective *** vital signs is a ubiquitous task that is commonly done in person by healthcare *** eliminate the need for in-person contact for vital sign measurement in the hospital setting,we developed ***,a mobile quadruped robotic *** system includes IR and RGB cameras for vital sign monitoring and a tablet computer for face-to-face medical *** is teleoperated by trained clinical staff to simultaneously measure the skin temperature,respiratory rate,and heart rate while maintaining social distancing from patients and without removing their *** enable accurate,contactless measurements on a mobile system without a static black body as reference,we propose novel methods for skin temperature compensation and respiratory rate measurement at various distances between the subject and the cameras,up to 5 *** compensation,the skin temperature MAE is 13℃.Using the proposed compensation method,the skin temperature MAE is reduced to 0.3℃.The respiratory rate method can provide continuous monitoring with a MAE of 1.6 BPM in 30s or rapid screening with a MAE of 2.1 BPM in *** the heart rate estimation,our system is able to achieve a MAE less than 8 BPM in 10s measured in arbitrary indoor light conditions at any distance below 2 m.

关键词： removing protective eliminate

Spearfishing-induced behavioral changes of an unharvested species inside and outside a marine protected area

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Current Zoology 2016年第1期62卷 39-44页

作者： Diem Samantha C. TRAN Katharine A. LANGEL Madison j. thomas Daniel T. BLUMSTEIN Department of Ecology and Evolutionary Biology University of California Los Angeles Los Angeles CA90095-1606 USA

By prohibiting fishing, marine protected areas （MPAs） provide a refuge for harvested species. Humans are often perceived as predators by prey and therefore respond fearfully to humans. Thus, fish responses to humans inside and outside of an MPA can provide insights into their perception of humans as a predatory threat. Previous studies have found differences in the distance that har- vested species of fish initiate flight （flight initiation distance--FID） from humans inside and outside an MPA, but less is known about unharvested species. We focused on whether the lined bristle- tooth Ctenochaetus striatus, an unharvested surgeonfish, can discriminate between a snorkeler and a snorkeler with a spear gun inside and outside of a no-take MPA in Mo＇orea, French Polynesia. Additionally, we incorporated starting distance （the distance between the person and prey at the start of an experimental approach）, a variable that has been found to be important in as- sessing prey escape decisions in terrestrial species, but that has not been extensively studied in aquatic systems. Lined bristletooth FID was significantly greater in the presence of a spear gun and varied depending on if the spear gun encounter was inside or outside of the MPA. These results imply a degree of sophistication of fish antipredator behavior, generate questions as to how a non- targeted species of fish could acquire fear of humans, and demonstrate that behavioral surveys can provide insights about antipredator behavior.

关键词： fear flight initiation distance learning marine protected area spearfishing starting distance.

Non-leaving-face property for marked surfaces

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Frontiers of Mathematics in China 2019年第3期14卷 521-534页

作者： thomas BRUSTLE jie ZHANG Departement de Mathematiques Universite de Sherbrooke Sherbrooke J1K 2R1 Canada School of Mathematics and Statistics Beijing Institute of Technology Beijing 100081 China

Abstract We consider the polytope arising from a marked surface by flips of triangulations. D. D. Sleator, R. E. Tarjan, and W. P. Thurston [j. Amer. Math. Soc., 1988, 1(3): 647 681] studied the diameter of the associahedron, which is the polytope arising from a marked disc by flips of triangulations. They showed that every shortest path between two vertices in a face does not leave that face. We give a new method, which is different from the one used by V. Disarlo and H. Parlier [arXiv: 1411.4285] to establish the same non-leaving-face property for all unpunctured marked surfaces.

关键词： Marked surface non-leaving-face property exchange graph

Two-day enema antibiotic therapy for parasite eradication and resolution of symptoms

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World journal of Gastroenterology 2020年第26期26卷 3792-3799页

作者： Niloufar Roshan Annabel Clancy Anoja W Gunaratne Antoinette LeBusque Denise Pilarinos thomas j Borody Centre for Digestive Diseases New South Wales 2046Australia

BACKGROUND Blastocystis hominis(***)and Dientamoeba fragilis(***)are two protozoan parasites of human bowel that are found throughout the *** is still debate about the pathogenicity of these protozoans,despite them being commonly associated with gastrointestinal symptoms and can cause health issue in both children and *** parasites are usually transmitted through faecal-oral contact particularly under poor hygiene conditions or food/water *** a person is infected,the parasites live in the large intestine and are passed in the *** To investigate the effect of triple antibiotic therapy using enema infusion in the treatment of *** and *** *** This retrospective longitudinal study was conducted in a single medical centre,which included fifty-four patients(≥18 years)who were positive for ***,*** or both between 2017 and *** treatment consisted of triple antibiotics that were infused over two consecutive days through rectal *** samples were collected from participants pre-and post-treatment and were tested for parasites using microscopy and polymerase chain ***’symptoms were recorded prior and after the treatment as well as patient demographic *** Patients(n=54),were either positive for ***(37%),***(35%)or both(28%).All patients completed the two-day treatment and no serious adverse effect was *** most common side effect experienced by the patients during the treatment was urine discolouration which was cleared by six weeks of *** symptoms reported prior to treatment were diarrhoea,abdominal pain,constipation and *** symptoms included abdominal discomfort,dizziness and blood in the ***-nine percent of patients completed a final stool test *** six weeks post-treatment,79%of patients cleared the parasites from their *** such as abdominal discomfort,dizziness and blood

关键词： Blastocystis hominis Dientamoeba fragilis Parasitic infection Antibiotics Triple therapy Rectal enema route

人文主义与后现代化主义之兴起及西方新区域地理学之发展

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地理学报 1999年第4期54卷 365-372页

作者：马润潮美国俄亥俄州州立爱克伦大学地理及规划系

近４０年来，西方人文地理学发生了巨大的变化。５０年代末期开始计量革命。７０年代初开始，人文主义、行为主义、结构主义与后现代化主义等观念涌现，它们对西方地理界起了不同程度的影响。演变至今，人文地理学可说是一个百花齐放的... 详细信息

近４０年来，西方人文地理学发生了巨大的变化。５０年代末期开始计量革命。７０年代初开始，人文主义、行为主义、结构主义与后现代化主义等观念涌现，它们对西方地理界起了不同程度的影响。演变至今，人文地理学可说是一个百花齐放的多元化时代。人文主义与后现代化主义在７０年代与８０年代期间，先后出现于西方地理学。二者与上列其他观点有根本的不同。在地理学上，它们强调各地情况都有其特性。同时，批判性的社会理论也在地理学中占了日益重要的地位。从８０年代开始，出现了一种新的区域地理学，它强调了人的能力及角色与社会结构如何影响地方特性的形成。

关键词：人文主义后现代化主义新区域地理学地方研究

Epigenetics of gastroenteropancreatic neuroendocrine tumors:A clinicopathologic perspective

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World journal of Gastrointestinal Oncology 2017年第9期9卷 341-353页

作者： Brendan M Finnerty Katherine D Gray Maureen D Moore Rasa Zarnegar thomas j FaheyⅢ Department of Surgery New York Presbyterian HospitalWeill Cornell MedicineNew YorkNY 10065United States

Gastroenteropancreatic neuroendocrine tumors(GEP-NETs) are a heterogeneous group of rare tumors whose site-specific tumor incidence and clinical behavior vary widely. Genetic alterations associated with familial inherited syndromes have been well defined; however, the genetic profile of sporadic tumors is less clear as their tumorigenesis does not appear to be controlled by classic oncogenes such as P53, RB, or KRAS. Even within GEP-NETs, there are no common oncogenic drivers; for example, DAXX/ATRX mutations are strongly implicated in the tumorigenesis of pancreatic but not small bowel NETs. Accordingly, the dysregulation of epigenetic mechanisms has been hypothesized as a potential regulator of GEPNET tumorigenesis and has become a major focus of recent studies. Despite the heterogeneity of tumor cohorts evaluated in these studies, it is obvious that there are methylation patterns, chromatin remodeling alterations, and microR NA and long non-coding RNA(lncR NA) differential expression profiles that are distinctive of GEPNETs, some of which are correlated with significant differences in clinical outcomes. Several translational studies have provided convincing data identifying potential prognostic biomarkers, and some of these have demonstrated preliminary success as serum biomarkers that can be used clinically. Nevertheless, there are many opportunities to further define the mechanisms by which these epigenetic modifications influence tumorigenesis, and this will provide better insight into their prognostic and therapeutic utility. Furthermore, these findings form the foundation for future studies evaluating the clinical efficacy of epigenetic modifications as prognostic biomarkers, as well as potential therapeutic targets.

关键词： Epigenetics Carcinoid Neuroendocrine MicroRNA Methylation Histone modifications Chromatin remodeling LncRNA

Towards intelligent geospatial data discovery:a machine learning framework for search ranking

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International journal of Digital Earth 2018年第9期11卷 956-971页

作者： Yongyao jiang Yun Li Chaowei Yang Fei Hu Edward MArmstrong thomas Huang David Moroni Lewis j.McGibbney Christopher j.Finch NSF Spatiotemporal Innovation Center and Department of Geography and GeoInformation Science George Mason UniversityFairfaxVAUSA NASA jet Propulsion Laboratory California Institute of TechnologyPasadenaCAUSA

Current search engines in most geospatial data portals tend to induce users to focus on one single-data characteristic dimension(*** and release date).This approach largely fails to take account of users’multidimensional preferences for geospatial data,and hence may likely result in a less than optimal user experience in discovering the most applicable *** study reports a machine learning framework to address the ranking challenge,the fundamental obstacle in geospatial data discovery,by(1)identifying a number of ranking features of geospatial data to represent users’multidimensional preferences by considering semantics,user behavior,spatial similarity,and static dataset metadata attributes;(2)applying a machine learning method to automatically learn a ranking function;and(3)proposing a system architecture to combine existing search-oriented open source software,semantic knowledge base,ranking feature extraction,and machine learning *** show that the machine learning approach outperforms other methods,in terms of both precision at K and normalized discounted cumulative *** an early attempt of utilizing machine learning to improve the search ranking in the geospatial domain,we expect this work to set an example for further research and open the door towards intelligent geospatial data discovery.

关键词： Learning to rank semantic search user behavior search engine big data metadata data relevancy data portal

Evolutionary Optimization: Pitfalls and Booby Traps

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journal of Computer Science & Technology 2012年第5期27卷 907-936页

作者： thomas Weise Raymond Chiong Ke Tang Nature Inspired Computation and Applications Laboratory School of Computer Science and Technology University of Science and Technology of China Hefei 230027 China Faculty of Higher Education Swinburne University of Technology 50 Melba Avenue Lilydale Victoria 3140 Australia

Evolutionary computation （EC）, a collective name rithms, is one of the fastest-growing areas in computer science. for a range of metaheuristic black-box optimization algo- Many manuals and ＂how-to＇s on the use of different EC methods as well as a variety of free or commercial software libraries are widely available nowadays. However, when one of these methods is applied to a real-world task, there can be many pitfalls and booby traps lurking certain aspects of the optimization problem that may lead to unsatisfactory results even if the algorithm appears to be correctly implemented and executed, These include the convergence issues, ruggedness, deceptiveness, and neutrality in the fitness landscape, epistasis, non-separability, noise leading to the need for robustness, as well as dimensionality and scalability issues, among others. In this article, we systematically discuss these related hindrances and present some possible remedies. The goal is to equip practitioners and researchers alike with a clear picture and understanding of what kind of problems can render EC applications unsuccessful and how to avoid them from the start.

关键词： evolutionary computing problem difficulty optimization meta-heuristics

The effect of temperature on ionic liquid modified Fe-N-C catalysts for alkaline oxygen reduction reaction

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journal of Energy Chemistry 2022年第5期31卷 324-329页

作者： thomas Wolker Kai Brunnengräber Ioanna Martinaiou Nick Lorenz Gui-Rong Zhang Ulrike I.Kramm Bastian j.M.Etzold Department of Chemistry Ernst-Berl-Institut für Technische und Makromolekulare ChemieTechnical University of Darmstadt64287 DarmstadtGermany Department of Chemistry Catalysts and Electrocatalysts GroupTechnical University of Darmstadt64287 DarmstadtGermany Graduate School of Excellence Energy Science and Engineering Technical University of Darmstadt64287 DarmstadtGermany Department of Materials and Earth Sciences Technical University of Darmstadt64287 DarmstadtGermany School of Chemical Engineering and Technology Tiangong UniversityTianjin 300387China

Modifying solid catalysts with an ionic liquid layer is an effective approach for boosting the performance of both Pt-based and non-precious metal catalysts toward the oxygen reduction reaction. While most studies operated at room temperature it remains unclear whether the IL-associated boosting effect can be maintained at elevated temperature, which is of high relevance for practical applications in low temperature fuel cells. Herein, Fe-N-C catalysts were modified by introducing small amounts of hydrophobic ionic liquid, resulting in boosted electrocatalytic activity towards the alkaline oxygen reduction reaction at room temperature. It is demonstrated that the boosting effect can be maintained and even strengthened when increasing the electrolyte temperature up to 70℃. These findings show for the first time that the incorporation of ionic liquid is a suited method to obtain advanced noble metal-free electrocatalysts that can be applied at operating temperature condition.

关键词： Oxygen reduction reaction Non-precious metal catalyst Ionic liquid Fe-N-C catalyst Temperature effect