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利用直接激发Rayleigh表面波的方法测量材料的声学非线性系数

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声学学报 2008年第4期33卷 378-384页

作者：税国双汪越胜 jianmin Qu jin-Yeon Kim laurence j. jacobs 北京交通大学力学所北京100044 School of Mechanical Engineering Georgia Institute of Technology Atlanta Georgia 30332-0405 USA

提出了利用直接激发Rayleigh表面波的方法测量材料的声学非线性系数。采用专门的信号源,将压电传感器安装在试件边缘直接激发Rayleigh表面波,利用激光干涉仪测量系统采集试件表面的Rayleigh波信号。对采集到的Rayleigh波信号进行FFT变换... 详细信息

提出了利用直接激发Rayleigh表面波的方法测量材料的声学非线性系数。采用专门的信号源,将压电传感器安装在试件边缘直接激发Rayleigh表面波,利用激光干涉仪测量系统采集试件表面的Rayleigh波信号。对采集到的Rayleigh波信号进行FFT变换,得到Rayleigh波信号中所包含的基频和高频成分,并据此进一步确定材料的声学非线性系数。对铝合金材料AA2024和AA6061的试验测量与分析结果表明,这种利用将压电传感器直接安装在试件边缘激发Rayleigh表面波的方法能够有效、准确地测量材料的声学非线性系数,可以为材料和结构早期力学性能退化的无损检测和评价提供一种有效的途径。

关键词： Rayleigh表面波干涉仪测量系统铝合金材料非线性系数 Rayleigh波声学激发传感器安装

Field Observations of the Vulnerable Impressed Tortoise, Manouria impressa, from Southern Laos and Notes on Local Chelonian Trade

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Asian Herpetological Research 2013年第2期4卷 151-154页

作者： thomas CALAME thomas N. E. GRAY Martha HURLEY Robert j. TIMMINS Khamhou THONGSAMOUTH WWF Greater Mekong House No. 39Unit 05Ban SaylomVientianeLao PDR Société d'Histoire Naturelle Alcide-d'Orbigny 57rue de Gergovie63170 AubièreFrance Global Wildlife Conservation

Observations of wild chelonians in Indochina are uncommon with most records and specimens coming from the commercial wildlife trade. During the surveys of the Xe Sap National Protected Area in southern Laos between February and May 2012, four impressed tortoises, Manouria impressa(IUCN Red List: Vulnerable) were found in three separate field locations. There are few published observations of this species in the wild. We also present data on threats and local value of chelonians in the wildlife trade.

关键词： Xe Sap National Protected Area Laos Manouria impressa wildlife trade

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电力系统可视化技术(英文)

电力系统自动化 2005年第16期29卷 60-65页

作者： thomas j.Overbye University of Illinois at Urbana-Champaign

介绍了可视化技术在电力系统潮流和最优潮流分析中应用的最新成果。讨论了应用动态变尺寸饼图和动画潮流箭头显示电力系统潮流;以及应用等高线显示母线电压和边际电价。此外,还讨论了交互式三维动画技术在电力系统可视化中的应用。所提... 详细信息

介绍了可视化技术在电力系统潮流和最优潮流分析中应用的最新成果。讨论了应用动态变尺寸饼图和动画潮流箭头显示电力系统潮流;以及应用等高线显示母线电压和边际电价。此外,还讨论了交互式三维动画技术在电力系统可视化中的应用。所提出的可视化技术不但可用于离线潮流和最优潮流分析,而且可用于电力系统控制中心在线潮流和最优潮流分析。

关键词：电力系统可视化等高线动画交互式三维技术

Overview of Clostridium difficile infection:implications for China

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Gastroenterology Report 2013年第3期1卷 153-158页

作者： Xinhua Chen j.thomas Lamont Division of Gastroenterology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA

The incidence and severity of Clostridium difficile infection(CDI)have dramatically increased in the Western world in recent *** contrast,CDI is rarely reported in China,possibly due to *** article briefly summarizes CDI incidence,management and preventive *** authors intend to raise awareness of this disease among Chinese physicians and health workers,in order to minimize the medical and economic burden of a potential epidemic in the future.

关键词： Clostridium difficile C.difficile infection(CDI) treatment prevention

Targeted therapy for capillary-venous malformations

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Signal Transduction and Targeted Therapy 2024年第7期9卷 3024-3039页

作者： Lola Zerbib Sophia Ladraa Antoine Fraissenon Charles Bayard Marina Firpion Quitterie Venot Sanela Protic Clément Hoguin Amandine thomas Sylvie Fraitag jean-Paul Duong Sophie Kaltenbach Estelle Balducci Coline Lefevre Patrick Villarese Vahid Asnafi Christine Broissand Nicolas Goudin Ivan Nemazanyy Gwennhael Autret Bertrand Tavitian Christophe Legendre Nadia Arzouk Veronique Minard-Colin Caroline Chopinet Michael Dussiot Denise MAdams Tristan Mirault Laurent Guibaud Paul Isenring Guillaume Canaud UniversitéParis Cité ParisFrance INSERM U1151 Institut Necker-Enfants MaladesParisFrance Service d’Imagerie Pédiatrique Hôpital Femme-Mère-EnfantHCLBronFrance CREATIS UMR 5220 Villeurbanne 69100France Service de Radiologie Mère-Enfant Hôpital NordSaint EtienneFrance Service d’Anatomie pathologique Hôpital Necker-Enfants MaladesAP-HPParisFrance Laboratoire d’Oncohématologie Hôpital Necker-Enfants MaladesAP-HPParisFrance Pharmacie Hôpital Necker-Enfants MaladesAP-HPParisFrance Necker Bio-Image Analysis INSERM US24/CNRS UMS 3633ParisFrance Platform for Metabolic Analyses Structure Fédérative de Recherche NeckerINSERM US24/CNRS UMS 3633ParisFrance Plateforme Imageries du Vivant Universitéde ParisPARCCINSERMParisFrance Service de Néphrologie Transplantation AdultesHôpital Necker-Enfants MaladesAP-HPParisFrance Service de Transplantation Hôpital La PitiéSalpétrièreAP-HPParisFrance Department of Pediatric and Adolescent Oncology INSERM 1015Gustave RoussyUniversitéParis-SaclayVillejuifFrance Service de Physiologie&Explorations Fonctionnelles Cardiovasculaires CHU de LilleLille 59000France INSERM U1163 Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic ImplicationsLaboratoire d’Excellence GR-ExParisFrance Division of Oncology Comprehensive Vascular Anomalies ProgramChildren’s Hospital of PhiladelphiaPhiladelphiaPAUSA Service de Médecine Vasculaire hôpital Européen Georges-PompidouParisFrance Nephrology Research Group L’Hôtel-Dieu de Québec Research CenterDepartment of MedicineFaculty of MedicineLaval UniversityQuebecQC G1R2J6Canada Unitéde médecine translationnelle et thérapies ciblées Hôpital Necker-Enfants MaladesAP-HPParisFrance CNRS UMR8253 Institut Necker-Enfants MaladesParisFrance

Sporadic venous malformations are genetic conditions primarily caused by somatic gain-of-function mutation of PIK3CA or TEK,an endothelial transmembrane receptor signaling through *** malformations are associated with pain,bleedings,thrombosis,pulmonary embolism,esthetic deformities and,in severe cases,life-threatening *** authorized medical treatment exists for patients with venous ***,we created a genetic mouse model of PIK3CA-related capillary venous malformations that replicates patient *** showed that these malformations only partially signal through AKT *** compared the efficacy of different drugs,including rapamycin,a mTORC1 inhibitor,miransertib,an AKT inhibitor and alpelisib,a PI3Kαinhibitor at improving the lesions seen in the mouse *** demonstrated the effectiveness of alpelisib in preventing vascular malformations’occurrence,improving the already established ones,and prolonging *** these findings,we were authorized to treat 25 patients with alpelisib,including 7 children displaying PIK3CA(n=16)or TEK(n=9)-related capillary venous malformations resistant to usual therapies including sirolimus,debulking surgical procedures or percutaneous *** assessed the volume of vascular malformations using magnetic resonance imaging(MRI)for each *** demonstrated improvement in all 25 *** malformations previously considered intractable were reduced and clinical symptoms were *** showed a decrease of 33.4%and 27.8%in the median volume of PIK3CA and TEK malformations respectively,over 6 months on *** conclusion,this study supports PI3Kαinhibition as a promising therapeutic strategy in patients with PIK3CA or TEK-related capillary venous malformations.

关键词： PIK3CA malformations venous

Salinity variation and hydrographic dynamics in the early Cambrian Nanhua Basin(South China)

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Science China Earth Sciences 2023年第6期66卷 1268-1278页

作者： Meng CHENG Zihu ZHANG Chengsheng jIN Wei WEI Haiyang WANG thomas j.ALGEO Chao LI State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation&Institute of Sedimentary Geology Chengdu University of TechnologyChengdu 610059China State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesWuhan 430074China International Center for Sedimentary Geochemistry and Biogeochemistry Research Chengdu University of TechnologyChengdu 610059China College of Resource Environment and Tourism Hubei University of Arts and ScienceXiangyang 441053China School of Earth Science China University of GeosciencesWuhan 430074China School of Earth Sciences and Engineering Nanjing UniversityNanjing 210023China State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesWuhan 430074China Department of Geology University of CincinnatiCincinnati 45221-0013USA

Despite intensive study of the early Cambrian Nanhua Basin(ECNB)in South China,its degree of connectedness to the open ocean remains uncertain,impeding analysis of contemporaneous oceanic redox evolution and its role in the Cambrian *** analyzed bulk-shale B/Ga,a newly proposed proxy for watermass salinity in ancient depositional systems,for three sections(Daotuo,Yuanjia,and Zhalagou)representing a range of water depths in the ECNB and spanning early Cambrian Stages 2 and *** B/Ga proxy records a salinity gradient in the basin,with increasing salinity from shallow-to deep-water areas,particularly during the deposition of black shales of the lower jiumenchong/Niutitang/Zhalagou *** gradient was probably due to the mixing of freshwater from adjacent landmasses with marine waters within a moderately restricted *** three study sections exhibit a monotonic rise in salinity over the~9-Myr study interval,reflecting increased watermass exchange with the open ocean due to regional tectonic and/or global sea-level *** improved watermass exchange may have weakened water-column stratification and reduced deep-water anoxia in the ECNB,contributing the enhanced oceanic oxygenation along with global environmental controls and further modulating the expression of the Cambrian Explosion recorded in Lower Cambrian sections of South *** study thus highlights the need for comprehensive analyses of hydrographic dynamics in marginal-marine settings that are used to explore co-evolutionary relationships between early animals and environmental oxygen levels.

关键词： B/Ga Boron Gallium Watermass restriction Cambrian Explosion Co-evolution

A novel method to fabricate TiAl intermetallic alloy 3D parts using additive manufacturing

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Defence Technology（防务技术） 2017年第2期13卷 72-76页

作者： j.j.S. Dilip H. Miyanaji Austin Lassell thomas L. Starr Brent Stucker Rapid Prototyping Center Department of Industrial EngineeringUniversity of LouisvilleLouisvilleKY 40292USA Department of Chemical Engineering University of LouisvilleLouisvilleKY 40292USA 3DSIM 1794 Olympic ParkwaySuite 110Park CityUT 84098USA

The present work explores the feasibility of fabricating porous 3D parts in TiAl intermetallic alloy directly from Tie6Ale4V and Al powders. This approach uses a binder jetting additive manufacturing process followed by reactive sintering. The results demonstrate that the present approach is successful for realizing parts in TiAl intermetallic alloy.

关键词： Additive manufacturing Binder jetting Intermetallic Titanium aluminide Reactive sintering

Engineering imaging probes and molecular machines for nanomedicine

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Science China(Life Sciences) 2012年第10期55卷 843-861页

作者： TONG Sheng CRADICK thomas j MA Yan DAI ZhiFei BAO Gang Department of Biomedical Engineering Georgia Institute of Technology and Emory University Atlanta GA 30332 USA Department of Biomedical Engineering College of Engineering Peking University Beijing 100871 China

Nanomedicine is an emerging field that integrates nanotechnology, biomolecular engineering, life sciences and medicine; it is expected to produce major breakthroughs in medical diagnostics and therapeutics. Due to the size-compatibility of nano-scale structures and devices with proteins and nucleic acids, the design, synthesis and application of nanoprobes, nanocarders and nanomachines provide unprecedented opportunities for achieving a better control of biological processes, and drastic im- provements in disease detection, therapy, and prevention. Recent advances in nanomedicine include the development of func- tional nanoparticle based molecular imaging probes, nano-structured materials as drug/gene carders for in vivo delivery, and engineered molecular machines for treating single-gene disorders. This review focuses on the development of molecular imag- ing probes and engineered nucleases for nanomedicine, including quantum dot bioconjugates, quantum dot-fluorescent protein FRET probes, molecular beacons, magnetic and gold nanoparticle based imaging contrast agents, and the design and validation of zinc finger nucleases （ZFNs） and TAL effector nucleases （TALENs） for gene targeting. The challenges in translating nano- medicine approaches to clinical applications are discussed.

关键词： nanomedicine imaging probe contrast agent drug delivery designer nuclease

Transferring Western Management Knowledge to China： Perceptions of Graduates from an American Executive MBA Program

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Frontiers of Business Research in China 2013年第1期7卷 82-105页

作者： Mahmood A. Zaidi thomas j. Norman Carlson School of Management University of Minnesota Minneapolis MN 55455 USA College of Business Administration and Public Policy California State University--Dominguez Hills Carson CA 90747 USA

As is well-known, China＇s rapid economic growth over the past decades has been impressive and this growth has driven the demand of qualified managers and professionals by both foreign and Chinese enterprises. This paper examines perceptions of the graduates of an American Executive MBA program, who experienced the transfer of Western management knowledge through team teaching and virtual student teams. The findings show that graduates are generally satisfied with their overall educational experience and its impact on their career in terms of promotions and compensation. Furthermore, the team teaching and global virtual student teams are viewed as valuable experiences.

关键词： EMBA graduate perceptions team teaching virtual internationalstudents teams