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Clinical, Psychological and Socio-Economic Profile of Women Consulting for Couple Infertility in the Yaounde Gynaeco-Obstetric and Paediatric Hospital

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Open Journal of Obstetrics and Gynecology 2023年第3期13卷 490-498页

作者： Junie Ngaha Isidore Tompeen Bilkissou Moustapha Claudia Toukem Anabelle Ako Brigitte Wandji laure menguene Pascal Foumane Gynaeco-Obstetric Unit Yaounde Gynaeco-Obstetric and Pediatric Hospital Yaounde Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde Yaounde Cameroon Department of Gynaecology and Obstetrics Higher Institute of Medical Technology University of Douala Douala Cameroon

Introduction: Infertility is defined as the inability to achieve a pregnancy after at least 12 months or more of regular unprotected sexual intercourse. Our main objective was to describe the clinical, psychological and socio-economic profile of women consulting for infertility in the Yaounde Gyneco-Obstetric and Pediatric Hospital. Methodology: This was a descriptive cross-sectional study with prospective data collection at the Yaounde Gyneco Obstetric and Pediatric Hospital over a period of 7 months from 1st December 2021 to 31st June 2022. Results: We included 171 patients. The mean age was 32.3 ± 5.5 years. The mean duration of infertility was 4.0 ± 3.7 years. Primary and secondary Infertility made up 31.6% and 68.4% of cases respectively. Past medical history was significant for Abortions (50%), Chlamydia and Mycoplasma infections (43.8%), chronic pelvic pain (49.7%) and endouterine manipulations (33.3%) of cases. Majority of our patients were stressed (76.6%). The most represented stress score was severe stress (66.1%). 51% of our patients were mentally depressed and 35.6% were anxious. Majority of them (74.9%) had low socio-economic status. Conclusion: Couple infertility is most often secondary. It triggers the onset of psychological problems like stress, mental depression and anxiety. Most of our patients had a low socio-economic status.

关键词： Psychological Profile Infertility Evaluation Scale Women

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Incidental and secondary findings in trio exome sequencing

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Genes & Diseases 2024年第4期11卷 152-154页

作者： Camille Cohen Emeline Bellanger Jeremie Mortreux laure Raymond Francois Vialard Rodolphe Dard Department of Genetics Centre Hospitalier Intercommunal de Poissy-Saint-Germain-en-LayePoissy 78300France RHuMA UMR-BREEDINRA-ENVA-UVSQMontigny le Bretonneux 78180France Service de Genetique Laboratoire Eurofins BiomnisLyon 69007France

Exome sequencing(ES)generates secondary findings(SFs)in 2%of tested individuals if one follows the American College of Medical Genetics and Genomics(ACMG)guide-lines.i,z2 However,the rate of incidental and secondary findings(ISFs)is higher in routine clinical practice because of(i)the use of trio ES instead of solo sequencing and(i)the exclusion of the incidental findings(IFs)of medical value concerning genes in the ACMG ***,it is not clear how sufficient is a restricted list of genes to detect every ISF of major clinical value;and what is the amount of additional workload for the laboratory.

关键词： routine clinical finding

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Deep Morphea in an Immunosuppressed Patient With Anti-U1RNP Myositis:A Case Report

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International Journal of Dermatology and Venereology 2024年第2期7卷 111-114页

作者： Ahmad Berjawi laure L.Irani Jinane R.El Khoury Department of Dermatology Gilbert and Rose Marie Chagoury School of MedicineLebanese American UniversityBeirut 1100Lebanon Department of Rheumatology Division of Internal MedicineGilbert and Rose Marie Chagoury School of MedicineLebanese American University Medical CenterBeirut 1100Lebanon

Introduction:Morphea is an inflammatory skin disease characterized by skin thickening due to increased collagen deposition in the dermis or subcutaneous ***-U1RNP myositis is a newly described entity characterized by myositis,arthritis,interstitial lung disease,and Raynaud *** present a case of a unique combination of deep morphea in a patient with anti-U1RNP *** presentation:A 64-year-old male with 5-year history of proximal muscle weakness,polyarthritis,Raynaud phenomenon,and dyspnea on multiple immunosuppressives presented with localized infiltrated,tight,and hyperpigmented plaques over the posterior thighs and mid-to-lower back developing over the last 2 years and limiting his *** workup revealed a positive ANA,anti-U1RNP antibody,anti-Jo1 antibody,and anti-Ro52 *** workup showed restrictive lung disease,kidney disease,and *** was diagnosed with anti-U1RNP *** biopsy of the back lesion showed deep ***:Association of deep morphea with anti-U1RNP myositis is not described prior in the *** of morphea is challenging since the patient is already on immunosuppressive *** patient failed methotrexate prior and is currently on Mycophenolate mofetil and Deflazacort which are reported as potential treatment for ***,physical therapy plus topical Tacrolimus were suggested as an initial measure to preserve the range of motion of his posterior thighs and *** is a case of progressive deep morphea developing in a patient with a unique autoimmune profile on immunosuppressive ***:Anti-U1RNP myositis is a challenging diagnosis and should be always thought of in patients with positive anti-U1RNP,myositis,interstitial lung disease,arthritis,kidney disease,and Raynaud ***,deep morphea treatment in immunosuppressed patients is challenging and different measures should be considered.

关键词： deep morphea immunosuppression anti-U1RNP myositis case report

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Application of Sigma Metric Analysis to Evaluate the Performance of the Biochemistry Analytical System in a Medical Biology Laboratory in Côte d’Ivoire

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Journal of Analytical Sciences, Methods and Instrumentation 2024年第1期14卷 14-21页

作者： Koffi Akissi Joelle Kouakou Francisk Kouadio Charlotte Yeo Karna Ahiboh Hugues Hauhouot-Attoungbré Marie-laure Biochemistry and Clinical Chemistry Unit CeDReS University Hospital of Treichville Abidjan Ivory Coast Department of Biochemistry Clinical Chemistry and Molecular Biology Faculty of Pharmaceutical and Biological Sciences University Felix Houphouet-Boigny Abidjan Ivory Coast

Introduction: The Six Sigma methodology is an opportunity for a better understanding of the performance of analytical methods and for a better adaptation of the quality control management policy of the medical biology laboratory. Using the sigma metric, this study assessed the performance of the Biochemistry analytical system of a medical biology laboratory in Côte d'Ivoire. Methods: Six Sigma methodology was applied to 3 analytes (alanine aminotransferase, glucose and creatinine). Performance indicators such as measurement imprecision and bias were determined based on the results of internal and external quality controls. The sigma number was calculated using the total allowable error values proposed by Ricos et al. Results: For both control levels, ALT had a sigma number greater than 6 (7.6 for normal control and 7.9 for pathological control). However, low sigma numbers, less than or equal to 2 for creatinine (1.4 for normal control and 2 for pathological control) and less than 1 for glucose were found. Conclusion: This study revealed good analytical performance of ALT from the point of view of 6 sigma analysis. However, modifications to the overall quality control procedure for glucose and creatinine are needed to improve their analytical performance. The study should be extended to the entire laboratory’s analytes in order to modify the strategies of quality control procedures based on metric analysis for an overall improvement in analytical performance.

关键词： Six Sigma Qualities Controls Bias Imprecision Total Allowable Error

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祖母绿与西方世界的面面观:历史、文化与象征

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中国宝石 2024年第4期 132-143页

作者： Marie-laure Cassius-Duranton L'ECOLE珠宝艺术中心

如今,对矿物种类的判定主要取决于其化学成分与原子结构。祖母绿是一种含铬和(或)钒的绿柱石。然而,在矿物学成为一门真正的学科之前,人们会使用其他方式来区分宝石,其中最重要的因素便是颜色。在西方历史和文化中,人们对祖母绿的想象... 详细信息

如今,对矿物种类的判定主要取决于其化学成分与原子结构。祖母绿是一种含铬和(或)钒的绿柱石。然而,在矿物学成为一门真正的学科之前,人们会使用其他方式来区分宝石,其中最重要的因素便是颜色。在西方历史和文化中,人们对祖母绿的想象与其颜色密切相关。尽管绿色具有丰富的象征意义,但在西方文明中,蓝色、红色等其他颜色要比绿色更为重要。

关键词：祖母绿矿物种类绿柱石矿物学原子结构化学成分西方文明宝石

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The Support Systems and Coping Strategies of Infertile Women Attending the Out-Patient Consultation Unit of CHRACERH Yaoundé, Cameroon: A Cross-Sectional Study

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Open Journal of Obstetrics and Gynecology 2024年第6期14卷 869-887页

作者： Emenguele Pascale Mpono Fidelia Mbi Kobenge Gabrielle laure Mengne Etienne Belinga Jean Marie Kasia Thomas Obinchemti Egbe Department of Obstetrics and Gynecology CHRACERH Yaound Yaound Cameroon Department of Obstetrics and Gynecology Faculty of Medicine and Biomedical Sciences University of Yaound 1 Yaound Cameroon Department of Obstetrics and Gynecology Faculty of Health Sciences University of Bamenda Bamenda Cameroon Department of Obstetrics and Gynecology Douala General Hospital Douala Cameroon Department of Obstetrics and Gynecology Faculty of Health Sciences University of Buea Buea Cameroon

Background: Infertility is a complex disorder with significant psycho-social and economic consequences. It globally affects 10% - 15% of couples. In Cameroon, little is known about what women do to overcome the psychosocial aspects of the disease. Objectives: This study aimed to identify the support systems and coping strategies of infertile women attending the outpatient consultation unit of the Gynaecological Endoscopic Surgery and Reproductive Teaching Hospital (CHRACERH), Yaoundé, Cameroon. Methods: A hospital-based cross-sectional study was conducted from the 14th of March to the 6th of April 2023 at CHRACERH Yaoundé. A total of 190 participants were recruited using a convenience sampling method. Data regarding socio-demographic characteristics, support systems and coping strategies were collected using a pretested questionnaire. Descriptive and analytic statistics were conducted using SPSS version 25. Results: The mean age of participants was 39.52 ± 7.64 years. The majority 78.9% of participants were workers (public, private sector, or traders) and were Christians 95.8%. The most common source of psychological support was from family 76.8 and husbands 72.63%. Most of the participants 89.5% resorted to prayer and getting busy 48.4% as a coping strategy. There was no statistically significant relationship between coping strategies and psychological disorders p > 0.05. Conclusion: The main support system of participants was family, husband, and friends. Prayer, getting busy and adoption were the most common coping strategies. There is a need for the Ministry of Public Health and other stakeholders to put in place other support systems and coping strategies (FELICIA) used elsewhere and provide adequate health education and infection control to prevent infertility in Cameroon.

关键词： Infertility Coping Strategies Support Systems Mental Health Women

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Prevalence of Work-Aggravated Asthma among Bakery Workers in Abidjan (Cote d’Ivoire)

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Health 2024年第3期16卷 204-217页

作者： Loukou Leandre Konan Esme Marie laure Essis Brou Michel Kouassi Marius Kedote Julius Fobil William Yavo Ossey Bernard Yapo Issaka Tiembre National Institute of Public Health Abidjan Cote d’Ivoire Interuniversity Doctoral Program Cotonou Benin Medical Sciences Training and Research Unit Department of Public Health and Biostatistics Felix Houphouet Boigny University Abidjan C&#244te d’Ivoire Global Environmental Occupational Health (GEOHealth) Accra Ghana UFR of Pharmaceutical and Biological Sciences Department of Public Health Felix Houphou&#235t Boigny University Abidjan Cote d’Ivoire Nangui Abrogoua University Abidjan C&#244te d’Ivoire National Institute of Public Hygiene Abidjan C&#244te d’Ivoire

Introduction: Work-aggravated asthma is pre-existing or concomitant asthma whose symptoms are aggravated by the work environment. The aim of this study was to determine the prevalence of this pathology and its associated factors among bakery workers in Abidjan. Materials and Methods: This descriptive and analytical cross-sectional study was conducted over a period of four (4) months from 18 December 2019 to 18 April 2020. Two questionnaires were used, one on employees and the other on the indoor environment of bakeries. In addition, a spirometry test was performed on all bakery workers. Statistical analysis was performed using stata 15.1 software. Results: A total of 599 bakery employees, including bakers (59.73%), sales assistants/ cashiers (23.52%), cleaners (6.34%) and administrative staff (10.18%), were investigated. The mean age was 30.8 ± 8 years, with a sex ratio (M/F) = 2.2. Asthma symptoms were found in 95 (15.86%) employees, of whom 74 (77.9%) had work-related asthma and 11 (14.9%) had asthma aggravated by work. The factors associated with work-aggravated asthma were personal or family history of allergy or atopy [ORa = 3.75;CI95%: 1.56 - 8.93;p = 0.003], exposure to dust [ORa = 5.01;CI95%: 1.43 - 7.50;p = 0.011] and humidity level (60% - 70%) [ORa = 1.80;CI 95%: 0.99 - 3.28;p = 0.05]. Conclusion: Work-aggravated asthma is a reality in bakeries in Abidjan, with an estimated prevalence of 14.9%. Two of the three factors associated with this condition suggest a link with indoor air pollution. Combating air pollution in these establishments must therefore be a priority for the relevant authorities, in order to provide employees with a working environment that protects their health.

关键词： Work-Aggravated Asthma Occupational Asthma Work-Related Asthma Bakeries Abidjan Ivory Coast

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全球日晒行为调查研究

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中华皮肤科杂志 2024年第7期57卷 672-673页

作者： Thierry Passeron Henry W. Lim Chee Leok Goh Hee Young Kang Fatimata Ly Akimichi Morita Jorge Ocampo-Candiani Susana Puig Sergio Schalka Wei Liu Anne-laure Demessant-Flavigny Caroline Le Floc’h Delphine Kerob Brigitte Dreno Jean Krutmann Department of Dermatology Côte d'Azur University Nice University Hospital Center Nice France INSERM U1065 C3M Côte d'Azur University Nice France Department of Dermatology Henry Ford Health Detroit Michigan USA National Skin Centre Singapore City Singapore Department of Dermatology Ajou University School of Medicine Suwon South Korea Department of Dermatology Cheikh Anta Diop Dakar University EPS Institute of Social Hygiene Dakar Senegal Department of Geriatric and Environmental Dermatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan Universidad Autonoma de Nuevo León Facultad de Medicina University Hospital “Dr. Jose E. González” Monterrey Mexico Dermatology Department Hospital Clinic de Barcelona Barcelona University Barcelona Spain Medcin Skin Research Center and Biochemistry Department Chemistry Institute of Sao Paulo University Sao Paulo Brazil Department of Dermatology The General Hospital of Air Force PLA Beijing China La Roche-Posay International Levallois-Perret France Nantes University Univ Angers INSERM Immunology and New Concepts in ImmunoTherapy INCIT UMR 1302 Nantes France IUF Leibniz Research Institute for Environmental Medicine Duesseldorf Germany Medical Faculty Heinrich-Heine-University Duesseldorf Germany

适量的日光照射有益于维生素D合成和情绪调节,但日光中的紫外线可能引发多种机体损伤,包括红斑、晒伤、光免疫抑制和光变态反应等急性损伤,以及皮肤癌、黄褐斑、炎症后色素沉着和光老化等慢性损伤。近期研究还显示,可见光(紫色至红色,40... 详细信息

适量的日光照射有益于维生素D合成和情绪调节,但日光中的紫外线可能引发多种机体损伤,包括红斑、晒伤、光免疫抑制和光变态反应等急性损伤,以及皮肤癌、黄褐斑、炎症后色素沉着和光老化等慢性损伤。近期研究还显示,可见光(紫色至红色,400~700nm)和红外线(700nm~1mm)也是皮肤光老化和光损伤的影响因素,可见光会导致黄褐斑等色素性疾病加重。

关键词：色素性疾病皮肤光老化光变态反应慢性损伤日光照射黄褐斑机体损伤维生素D

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Dietary Diversity and Food Security Status among Cameroonian Adults Living in Semi-Urban Areas: A Cross-Sectional Study

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Food and Nutrition Sciences 2024年第7期15卷 548-564页

作者： Tonou Boris Ronald Tchuente Pauline Vervaine Hagbe Eliane Flore Eyenga Kemadjou Ruth Edwige Dibacto Ngassa Dany Joël Ngoumen Fotso Janvier Aime Youovop Nguemto Roussel Guy Takuissu Judith laure Ngondi Julius Enyong Oben Department of Biochemistry Faculty of Science University of Yaound 1 Yaound Cameroon Centre for Food Food Security and Nutrition Research Institute of Medical Research and Medicinal Plant Studies Yaound Cameroon Center of Nutrition and Functional Foods Yaound Cameroon

Introduction: Food security is one of the greatest challenges that most African countries face. It is a concept that considers not only food quantity but also food quality. The objective of this study was to describe dietary diversity and food security status at the individual level in Cameroonian populations. Methods: A total of 1180 men and women aged 20 and over and living in the West, North West, and Littoral regions of Cameroon were recruited. Data on dietary habits were collected through the frequency of consumption of various food groups. Dietary diversity was assessed using a 24-hour dietary recall. Food security status was determined by combining two indicators (food consumption score and individual food diversity score). Results: The mean dietary diversity score of the population was 3.53 ± 1.44, p Conclusion: The diet diversity of adults living in the West, North West, and Littoral regions of Cameroon is medium. Although half of the study population was food secure, there is a need to implement food security policies further to reduce food insecurity among the Cameroonian population.

关键词： Dietary Diversity Individual Food Security Littoral West North West Cameroon

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Evaluation of the Quality of Micturition in Patients Who Underwent Anastomotic Urethroplasty at the Yaounde Central Hospital, Cameroon

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Open Journal of Urology 2024年第2期14卷 115-127页

作者： Achille Aurele Mbassi Landry Oriole Mbouche Junior Mekeme Mekeme Jean Crepin Eloundou Nkolo Bright Che Awondo Jean Cedrik Fouda Frantz Guy Epoupa Ngalle Cyril Kamadjou Pamela Anaba laure Pierre Joseph Fouda Fru Forbuzshi III Angwafo Higher Institute of Medical Technology Yaounde Cameroon Higher Institute of Health Sciences Bangangte Cameroon Urology and Andrology Department Yaounde Central Hospital Yaounde Cameroon Department of Surgery and Subspecialties Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde Cameroon Yaounde Gynecology Obstetrics and Pediatric Hospital Yaounde Cameroon

Introduction: Radiological investigation which is the gold standard to perform following anastomotic urethroplasty in order to evaluate the quality of micturition is costly. In our context, due to financial limitations, reconstructive urologists prefer to use the uroflowmetry in order to assess the micturition post-surgery. Therefore, the objective of the study was to assess the quality of micturition using the uroflowmetry after anastomotic urethroplasty. Methodology: We conducted an 11-year retrospective review (1st January 2006-31st December 2017) and a cross-sectional descriptive observational study for a period of 8 months (November 2017-June 2018) at the Urology and Andrology Department of the Yaounde Central Hospital (YCH) of patients who were diagnosed with urethral stenosis and underwent an anastomotic urethroplasty at the YCH. We excluded patients who had incomplete files, patients lost to follow-up and did not do pre-operative uroflowmetry. Quality of micturition was evaluated using a uroflowmetry. Data was analyzed using EPI info 7.0. Parametric variables were reported as means and standard deviations and percentages and counts were used to report categorical variables. Results: We had a sample of 60 patients. The mean age was 42 ± 5 years with extremes ranging from 20 to 76 years. Twenty-seven (27) patients, or 45%, had no post-operative complications, and those who did had a urinary tract infection (26.70%). In our series, we had 82% excellent results (patient satisfied with his urination with bell-shaped urinary stream and urinary flow greater than or equal to 15 ml/sec);15% good results (patient with moderate dysuria with average urinary stream and urinary flow between 10 and 14.9 ml/sec) and 3% poor results (severe dysuria with urinary flow less than 10 ml/sec, urinary retention or urinary incontinence). Based on these results we can say that the success rate in our series was 97%. 96.70% of patients were satisfied against 3.3%

关键词： Urethra Stricture Anastomotic Urethroplasty

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