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Liver cirrhosis and left ventricle diastolic dysfunction: Systematic review

World Journal of Gastroenterology 2019年第32期25卷 4779-4795页

作者： Ieva Stundiene Julija Sarnelyte Ausma Norkute Sigita Aidietiene Valentina Liakina laura masalaite Jonas Valantinas Vilnius University Institute of Clinical MedicineClinic of GastroenterologyNephrourology and SurgeryVilnius UniversityVilnius LT-03101Lithuania Vilnius University Institute of Clinical MedicineClinic of Internal diseasesFamily medicine and OncologyVilnius UniversityVilnius LT-03101Lithuania Vilnius University Institute of Clinical MedicineClinic of Cardiology and AngiologyVilnius UniversityVilnius LT-03101Lithuania Vilnius Gediminas Technical University Faculty of Fundamental SciencesDepartment of Chemistry and BioengineeringVilnius LT-10223Lithuania

BACKGROUND Liver cirrhosis is a chronic hepatic disease which is associated with cardiovascular *** circulation in liver cirrhosis causes functional and structural cardiac *** prevalence of left ventricle diastolic dysfunction(LVDD)in cirrhotic patients ranges from 25.7%to as high as 81.4%as reported in different *** several studies the severity of diastolic dysfunction(DD)correlated with a degree of liver failure and the rate of dysfunction was higher in patients with decompensated cirrhosis compared with *** directions of comprehensive assessment of cardiac function in cirrhotic patients might provide a better prognosis for these *** To clarify the correlation between the severity of liver cirrhosis and left ventricle diastolic dysfunction in the existing *** Through January and February of 2019 at Vilnius University we conducted a systematic review of the global existing literature on the prevalence of left ventricle diastolic dysfunction in patients with liver *** searched for articles in PubMed,Medline and Web of science *** were selected by using adequate inclusion and exclusion *** interest was the outcome of likely correlation between the severity of cirrhosis[evaluated by Child-Pugh classes,Model For End-Stage Liver Disease(MELD)scores]and left ventricle diastolic dysfunction[classified according to American Society of Echocardiography(ASE)guidelines(2009,2016)],as well as relative risk of dysfunction in cirrhotic *** analyses were performed to evaluate the ratio and grades of left ventricle diastolic dysfunction with respect to cirrhosis *** A total of 1149 articles and abstracts met the initial search *** articles which met the predefined eligibility criteria were included in the final ***,1067 patients(out of them 723 men)with liver cirrhosis were evaluated for left ventricle diastolic dysf

关键词： Liver cirrhosis Left ventricle Diastolic dysfunction Correlation Echocardiography Systematic review

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