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<i>N</i>-Acetylated Gemini Surfactants: Synthesis, Surface-Active Properties, Antifungal Activity, and Ecotoxicity Bioassays

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Advances in Chemical Engineering and Science 2015年第2期5卷 215-224页

作者： laura M. Machuca Ulises Reno Silvana C. Plem Ana María Gagneten Marcelo C. Murguía Laboratory of Applied Chemistry Faculty of Biochemistry and Biological Sciences National University of Litoral Santa Fe Argentina Laboratory of Ecotoxicology Faculty of Humanities and Sciences National University of Litoral Santa Fe Argentina

A series of N-acetylated cationic gemini surfactants (3a-e) having dimeric structures derived from tertiary amines were synthesized. Their antifungal potency and surface properties were determined. It also studied the acute toxicity of the molecule with the best performance and the best water solubility (3e) through Chlorella vulgaris and daphnia magna bioassays. The results were compared to those obtained for a commercially available reference compound 2-(thiocyanomethylthio) benzothiazole (TCMTB). Parameters such as surface tension (ϒCMC), critical micelle concentration (CMC), surface excess concentration (Γ), and area per molecule (A) were determined. The resulting values indicated that the five gemini surfactants are characterized by good surface-active and self-aggregation properties. All surfactants were tested to evaluate their antifungal activity. Six fungal strains were used to conduct the study. The minimum inhibitory concentration (MIC) value was measured by the fungal growth inhibition. The results of the MICs were compared with two commercially available reference compounds (fluconazole and TCMTB). The least active molecule was 3e, but 3b and 3d were found to be the most potent compounds with a similar activity for all strains. Candida albicans was the most sensitive one. In contrast, Aspergillus niger was resistant. Ecotoxicity of gemini 3e was assessed: the commercial formulation (TCMTB) was between three and four orders of magnitude more toxic than the gemini one for the biological species tested.

关键词： Gemini Surfactants Surface-Active Properties Antifungal Activity Ecotoxicity Bioassays

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苦丁茶提取物多酚含量与抗氧化活性的测定

茶叶科学 2008年第4期28卷 289-293页

作者：刘丽香梁兴飞孙怡 Tanguy laura 叶红曾晓雄南京农业大学食品科技学院苏南京210095 department of food Engineering Polytech＇Lille 59655 Villenewe d＇Asqc France

首先用不同的有机溶剂分部萃取苦丁茶(Ilex kudincha ***)热水提取物(粗提物),得到氯仿萃取物、乙酸乙酯萃取物、正丁醇萃取物及萃取剩余物,然后采用folin-Ciocalteu比色法测定粗提物和各萃取物的多酚含量,同时应用dPPH法、TEAC法和fRA... 详细信息

首先用不同的有机溶剂分部萃取苦丁茶(Ilex kudincha ***)热水提取物(粗提物),得到氯仿萃取物、乙酸乙酯萃取物、正丁醇萃取物及萃取剩余物,然后采用folin-Ciocalteu比色法测定粗提物和各萃取物的多酚含量,同时应用dPPH法、TEAC法和fRAP法分别测定粗提物和各萃取物的自由基清除能力和还原fe3+能力。结果表明,苦丁茶提取物具有较高的多酚含量和较强的抗氧化能力;dPPH法和fRAP法测定各提取物抗氧化能力的结果为乙酸乙酯萃取物>正丁醇萃取物>粗提物>萃取剩余物>氯仿萃取物,TEAC法测定结果为乙酸乙酯萃取物>正丁醇萃取物>粗提物>氯仿萃取物>萃取剩余物;多酚含量与抗氧化能力之间、所用抗氧化测定方法之间均存在较好的相关性。

关键词：苦丁茶多酚抗氧化比色法相关性

Notes for genera:Ascomycota

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fungal diversity 2017年第5期86卷 1-594页

作者： nalin N.Wijayawardene Kevin d.Hyde Kunhiraman C.Rajeshkumar david L.Hawksworth Hugo Madrid Paul M.Kirk Uwe Braun Rajshree V.Singh Pedro W.Crous Martin Kukwa Robert Lücking Cletus P.Kurtzman Andrey Yurkov danny Haelewaters Andre´Aptroot H.Thorsten Lumbsch Einar Timdal damien Ertz Javier Etayo Alan J.L.Phillips Johannes Z.Groenewald Moslem Papizadeh laura Selbmann Monika C.dayarathne Gothamie Weerakoon E.B.Gareth Jones Satinee Suetrong Qing Tian Rafael f.Castanda-Ruiz Ali H.Bahkali Ka-Lai Pang Kazuaki Tanaka dong Qin dai Jariya Sakayaroj Martina Hujslová Lorenzo Lombard Belle d.Shenoy Ave Suija Sajeewa S.N.Maharachchikumbura Kasun M.Thambugala dhanushka N.Wanasinghe Bharati O.Sharma Subhash Gaikwad Gargee Pandit laura Zucconi Silvano Onofri Eleonora Egidi Huzefa A.Raja Rampai Kodsueb Marcela E.S.Caceres Sergio Perez-Ortega Patrícia O.fiuza Josiane Santana Monteiro Larissa N.Vasilyeva Roger G.Shivas Maria Prieto Mats Wedin Ibai Olariaga Adebola Azeez Lateef Yamini Agrawal Seyed Abolhassan Shahzadeh fazeli Mohammad Ali Amoozegar Guo Zhu Zhao Walter P.Pfliegler Gunjan Sharma Magdalena Oset Mohamed A.Abdel-Wahab Susumu Takamatsu Konstanze Bensch Nimali Indeewari de Silva Andréde Kesel Anuruddha Karunarathna Saranyaphat Boonmee donald H.Pfister Yong-Zhong Lu Zong-Long Luo nattawut Boonyuen dinushani A.daranagama Indunil C.Senanayake Subashini C.Jayasiri Milan C.Samarakoon Xiang-Yu Zeng Mingkwan doilom Luis Quijada Sillma Rampadarath Gabriela Heredia Asha J.dissanayake Ruvishika S.Jayawardana Rekhani H.Perera Li Zhou Tang Chayanard Phukhamsakda Margarita Hernańdez-Restrepo Xiaoya Ma Saowaluck Tibpromma Luis f.P.Gusmao darshani Weerahewa Samantha C.Karunarathna Key Laboratory for Plant diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China Center of Excellence in fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Mushroom Research foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand national fungal Culture Collection of India(NfCCI) Biodiversity and Palaeobiology(Fungi)GroupAgharkar Research InstitutePuneMaharashtra 411004India Royal Botanic Gardens KewRichmondSurrey TW93DSUK department of Life Sciences The Natural History MuseumCromwell RoadLondon SW75BDUK Jilin Agricultural University Changchun 130118JilinPeople’s Republic of China Centro de Geno´mica y Bioinforma´tica Facultad de CienciasUniversidad Mayor de ChileCamino La Pira´mide 5750HuechurabaSantiagoChile Martin-Luther-Universita¨t Institut fu¨r BiologieBereich Geobotanik und Botanischer GartenHerbariumNeuwerk 2106099 Halle(Saale)Germany Westerdijk fungal Biodiversity Institute Uppsalalaan 83584 CT UtrechtThe Netherlands department of Plant Taxonomy and nature Conservation Faculty of BiologyUniversity of Gdan´skWita Stwosza 5980-308 Gdan´skPoland Botanic Garden and Botanical Museum Königin-Luise-Str.6-814195 BerlinGermany Mycotoxin Prevention and Applied Microbiology Research Unit National Center for Agricultural Utilization ResearchAgricultural Research ServiceU.S.Department of AgriculturePeoriaIL 61604USA Leibniz Institute dSMZ-German Collection of Microorganisms and Cell Cultures Inhoffenstraße 7B38124 BrunswickGermany farlow Reference Library and Herbarium of Cryptogamic Botany Harvard University22 Divinity AvenueCambridgeMA 02138USA department of Organismic and Evolutionary Biology Harvard University22 Divinity AvenueCambridgeMA 02138USA ABL Herbarium G.v.d.Veenstraat 1073762 XK SoestThe Netherlands Science&Education The Field Museum1400

Knowledge of the relationships and thus the classification of fungi,has developed rapidly with increasingly widespread use of molecular techniques,over the past 10–15 years,and continues to *** genera have been found to be polyphyletic,and their generic concepts have subsequently been *** names have thus been introduced for species which are phylogenetically distinct from the type species of particular *** ending of the separate naming of morphs of the same species in 2011,has also caused changes in fungal generic *** order to facilitate access to all important changes,it was desirable to compile these in a single *** present article provides a list of generic names of Ascomycota(approximately 6500 accepted names published to the end of 2016),including those which are *** and summaries of the changes since the last edition of‘Ainsworth&Bisby’s dictionary of the fungi’in 2008 are *** notes include the number of accepted species,classification,type species(with location of the type material),culture availability,life-styles,distribution,and selected publications that have appeared since *** work is intended to provide the foundation for updating the ascomycete component of the"Without prejudice list of generic names of fungi"published in 2013,which will be developed into a list of protected generic *** will be subjected to the XIXth International Botanical Congress in Shenzhen in July 2017 agreeing to a modification in the rules relating to protected lists,and scrutiny by procedures determined by the Nomenclature Committee for fungi(NCf).The previously invalidly published generic names Barriopsis,Collophora(as Collophorina),Cryomyces,dematiopleospora,Heterospora(as Heterosporicola),Lithophila,Palmomyces(as Palmaria)and Saxomyces are validated,as are two previously invalid family names,Bartaliniaceae and *** species of Lalaria,which were invalidly published are trans

关键词： Article 59 Classification One name Pleomorphic fungi Taxonomy

Biological Corridors as a Connectivity Tool in the Region of the Great American Chaco:Identification of Biodiversity Hotspots in the Ecoregions of the Paraguayan Chaco

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Research in Ecology 2020年第1期2卷 27-36页

作者： María fátima Mereles Gloria Céspedes JoséLuís Cartes Rosalía Goerzen Juanade Egea-Elsam laura Rodríguez Alberto Yanosky laura Villalba Andrea Weiler Pier Cacciali Centro para el desarrollo de la Investigación Científica(CEdIC) Asunción-Paraguay y Programa Nacional de Incentivo a Investigadores(PRONII-CONACYT) Asociación Etnobotánica Paraguaya(AEPY) San Lorenzo-Paraguay y Programa Nacional de Incentivo a Investigadores(PRONII-CONACYT) Asociación Guyra-Paraguay y Programa nacional de Incentivo a Investigadores(PRONII-COnaCYT) Cooperativa fernheim FiladelfiaChaco fundación Moisés Bertoni Universidad nacional de Asunción Facultad de Ciencias Exactas y NaturalesDirección de Biología

This work presents the main biodiversity hotspots existing in the Paraguayan Chaco and is an update of the results obtained in the first Ecoregional Assessment of the Great American *** are the results of a series of workshops that included scientific and technical discussions carried out by local experts in zoology,botany,forestry,soil science,and hydrogeology applying a biodiversity vision of 25-30 years for the territory,after overlapping the maps of the first assessment with that of the advance of the changes of land use in the *** for detecting biodiversity hotspots were discussed,including:permanent and temporary watercourses,other bodies of water such as fresh and salty lagoons,reserve areas of different categories,as well as important bird areas(IBAs),RAMSAR areas and others,which must be connected in the future,combining the production areas with the conservation of biodiversity.

关键词： Conservation fauna flora Endemic species Sustainable use

灰烬中重见希望在遭大火吞噬的加州小镇,壁画家看到使命

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空中英语教室（高级版．彭蒙惠英语） 2019年第12期 28-29,45,46页

作者： laura Newberry 徐佩仪(译) 不详

妮可维迪站在车道上,静静地看着那面墙壁,心中出奇地平静。原本的家烧得仅剩灰烬、残垣与锈蚀,她没想到,在这个小镇居然能够再次找到平静。然而看到墙壁上细心绘制的女儿的肖像,她感到十分宽慰。火灾后的好几个星期,她的女儿艾琳娜拒... 详细信息

妮可维迪站在车道上,静静地看着那面墙壁,心中出奇地平静。原本的家烧得仅剩灰烬、残垣与锈蚀,她没想到,在这个小镇居然能够再次找到平静。然而看到墙壁上细心绘制的女儿的肖像,她感到十分宽慰。火灾后的好几个星期,她的女儿艾琳娜拒绝踏进加州天堂镇一步。妮可因此也只去了两次:第一次是去看看是否有逃过火劫的财物,之后则是去看那个壁画。妮可在奇哥中学时期的老朋友贤恩格莱姆从事商业艺术创作,妮可托他在仅剩的那面墙上自由作画。

关键词：艺术创作天堂镇格莱姆灰烬艾琳娜加州小镇

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没有终点的列车 5

2018年

作者：（英）劳拉·麦克维（laura McVeigh）

“这就是我的旅程，一段我从不希望踏上的旅程。”15岁的阿芙萨娜藏在老式列车的座椅下，当列车员经过时，她蜷起双腿，屏住呼吸-“千万不要发现我！”漫长而艰险的离乡逃亡之旅仿佛永无终点。过去的种种在她脑中飞速闪过：战火持续蔓... 详细信息

ISBN: (数字)9787508684208

ISBN: (纸本)9787508684208

“这就是我的旅程，一段我从不希望踏上的旅程。”15岁的阿芙萨娜藏在老式列车的座椅下，当列车员经过时，她蜷起双腿，屏住呼吸-“千万不要发现我！”漫长而艰险的离乡逃亡之旅仿佛永无终点。过去的种种在她脑中飞速闪过：战火持续蔓延，父母的好友离奇死亡，全家人被迫逃离喀布尔，投奔远亲；山居岁月短暂而美好，让他们以为-幸福，触手可及。然而，塔利班势力的逐渐扩大、突如其来的天灾人祸，毁掉了所有希望。痛失亲人的悲痛与无助，难民营里的孤独与绝望，独自寻亲的不懈与执着，以及紫荆树下的惊天秘密……“这就是我的旅程，一段我从不希望踏上的旅程。”15岁的阿芙萨娜藏在老式列车的座椅下，当列车员经过时，她蜷起双腿，屏住呼吸- 更多...

关键词：长篇小说

来源：汇雅图书（南通市图书馆... 评论

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家庭医生对自身管理阿片类药物危机的看法

中国全科医学 2019年第31期22卷 3804-3804页

作者： laura d MARIANNE S naTASHA K 本刊编辑部

目的探索家庭医生对阿片类药物处方和慢性疼痛管理的看法,以更好地了解初级保健中开具更安全处方的障碍及可能成为实践变异潜在驱动因素的观点差异。方法该研究使用了探索性定性研究设计。于2017年6月和7月对安大略省22名家庭医生进行... 详细信息

目的探索家庭医生对阿片类药物处方和慢性疼痛管理的看法,以更好地了解初级保健中开具更安全处方的障碍及可能成为实践变异潜在驱动因素的观点差异。方法该研究使用了探索性定性研究设计。于2017年6月和7月对安大略省22名家庭医生进行半结构化访谈,并对访谈内容进行归纳编码。采用主题分析确定主题,采用框架分析探讨医生人口统计学资料对开具处方的影响。

关键词：家庭医生主题分析阿片类药物初级保健统计学资料慢性疼痛安大略省框架分析

COVId-19 mental health care toolkit:an international collaborative effort by Early Career Psychiatrists section

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General Psychiatry 2020年第5期33卷 352-355页

作者： frances Adiukwu laura Orsolini drita Gashi Bytyçi Samer El Hayek Jairo M Gonzalez-diaz Amine Larnaout Paolo Grandinetti Marwa Nofal Victor Pereira-Sanchez Mariana Pinto da Costa Ramdas Ransing Andre Luiz Schuh Teixeira Mohammadreza Shalbafan Joan Soler-Vidal Zulvia Syarif Ganesh Kudva Kundadak Rodrigo Ramalho department of Neuropsychiatry University of Port Harcourt Teaching HospitalChobaRiversNigeria department of Clinical Neurosciences/dIMSC School of MedicinePolytechnic University of MarcheAnconaMarcheItaly Mental Health Center Prizren Hospital and University Clinical Service of KosovoPrizrenKosovo department of Psychiatry American University of BeirutBeirutLebanon CERSAME School of Medicine and Health SciencesUniversidad del Rosario-Clinica Nuestra Senora de la PazBogotaColombia Psychiatry department d Razi Hospitalfaculty of Medicine of TunisTunis El Manar UniversityTunisTunisia Addictions Service(Serd) Department of Territorial AssistanceASL TeramoTeramoItaly Helwan Mental Health Hospital CairoEgypt department of Child and Adolescent Psychiatry NYU Grossman School of MedicineNew YorkNew YorkUSA Unit for Social and Community Psychiatry(WHO Collaborating Centre for Mental Health Services development) Queen Mary University of LondonLondonUK Institute of Biomedical Sciences Abel Salazar University of PortoPortoPortugal Hospital de Magalhaes Lemos PortoPortugal department of Psychiatry BKL Walawalkar Rural Medical CollegeSawardeRatnagiriIndia department of Childhood and Adolescent Psychiatry Universidade Federal do Rio Grande do SulPorto AlegreRSBrazil Mental Health Research Center Department of PsychiatrySchool of MedicineIran University of Medical SciencesTehranIran(the Islamic Republic of) fidmag Research foundation Hermanas HospitalariasBarcelonaSpain department of Psychiatry Tarakan General HospitalJakartaIndonesia Early Psychosis Intervention Programme Institute of Mental HealthSingapore department of Social and Community Health School of Populatin HealthUniversity of AucklandAucklandNew Zealand

The collaborative effort of an international research team from the Early Career Psychiatrists section of the World Psychiatry Association has brought about an easy-to-use,quick and stepwise mental health care toolkit for the identification and appropriate referral of those in need of mental health care during the *** simple guide can be applied in the general outpatient setting and is catered for all healthcare professionals,regardless of their expertise within the mental health field with minimal *** is our hope that by incorporating this toolkit into our daily clinical care during the pandemic for high-risk patients and patients with non-specific complaints,we will be able to bridge the mental health gap present in our society.

关键词： Psychiat section clinical

Infections following Kidney Transplant in Children: A Single-Center Study

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Open Journal of Nephrology 2014年第3期4卷 117-124页

作者： Alexandre fernandes Liliana Rocha Teresa Costa Paula Matos Maria Sameiro faria laura Marques Conceicao Mota Antonio Castro Henriques Pediatric Infectious diseases and Immunodeficiency department Centro Hospitalar do PortoOportoPortugal Pediatric Nephrology department Centro Hospitalar do PortoOportoPortugal Kidney Transplant department Centro Hospitalar do PortoOportoPortugal

Introduction: Infections are a major cause of morbidity and mortality in pediatric patients undergoing kidney transplantation (KT). Aim and Methods: To determine the patterns of infectious complications during the first 6 months post transplantation, we report our single center experience with data from pediatric kidney recipients transplanted between 2006 and 2011. Results: Thirty-two children (20 males) were submitted to KT. The most common cause of end-stage renal disease (ESRd) was congenital anomalies of the kidney and urinary tract (CAKUT) accounting for 62%. Over the first 6 months post-transplant period, twenty-eight (87.5%) children developed a total of 77 infections, mainly urinary tract infections (UTI) (64.9%). CAKUT etiology of ESRd and UTI before KT increased the risk to develop more than one episode of UTI [71.4% vs. 14.3% and 81.8% vs. 18.2%, respectively;p fections occurred. Cytomegalovirus (CMV) was the most common opportunistic pathogen, occurred in 11 patients and was more frequently in those with a donor (d)+/recipient (R)- CMV sero-status [74.5% vs. 25.5% (p disease with nephropathy and meningitis was registered. The majority of infectious episodes had mild or moderate severity. No deaths occurred. Conclusion: A significant number of patients presented infectious complications during the first 6 months post transplantation. UTI are the most common type of infection, followed by viral infections, particularly CMV. Recognition, prevention and early treatment of infections are of major importance.

关键词： CMV Infection Immunosuppression Kidney Transplantation Urinary Tract Infections