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A deep Learning-Based Approach for Road Surface damage detection

Computers, Materials & Continua 2022年第11期73卷 3403-3418页

作者： Bakhytzhan Kulambayev Gulbakhram Beissenova nazbek Katayev Bayan Abduraimova Lyazzat Zhaidakbayeva Alua Sarbassova Oxana Akhmetova Sapar Issayev laura Suleimenova Syrym Kasenov Kunsulu Shadinova Abay Shyrakbayev International Information Technology University AlmatyKazakhstan M.Auezov South Kazakhstan University ShymkentKazakhstan University of friendship of People’s Academician A.Kuatbekov ShymkentKazakhstan Kazakh national Women’s Teacher Training University AlmatyKazakhstan L.N.Gumilyov Eurasian national University Nur-SultanKazakhstan Al-farabi Kazakh national University AlmatyKazakhstan Abai Kazakh national Pedagogical University AlmatyKazakhstan South Kazakhstan State Pedagogical University ShymkentKazakhstan Asfendiyarov Kazakh national Medical University AlmatyKazakhstan International Taraz Innovative Institute TarazKazakhstan

Timely detection and elimination of damage in areas with excessive vehicle loading can reduce the risk of road ***,various methods of photo and video surveillance are used to monitor the condition of the road *** manual approach to evaluation and analysis of the received data can take a protracted period of ***,it is necessary to improve the procedures for inspection and assessment of the condition of control objects with the help of computer vision and deep learning *** this paper,we propose a model based on Mask Region-based Convolutional Neural Network(Mask R-CNN)architecture for identifying defects of the road surface in the real-time *** shows the process of collecting and the features of the training samples and the deep neural network(dNN)training process,taking into account the specifics of the problems *** the software implementation of the proposed architecture,the Python programming language and the Tensorflow framework were *** use of the proposed model is effective even in conditions of a limited amount of source *** as a result of experiments,a high degree of repeatability of the results was *** to the metrics,Mask R-CNN gave the high detection and segmentation results showing 0.9214,0.9876,0.9571 precision,recall,and f1-score respectively in road damage detection,and Intersection over Union(IoU)-0.3488 and dice similarity coefficient-0.7381 in segmentation of road damages.

关键词： Road damage mask R-CNN deep learning detection segmentation

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Preparation of a Slow Release Biofertilizer from a Polymeric Urea-formaldehyde Matrix (PUfM)

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Phyton-International Journal of Experimental Botany 2019年第4期88卷 459-470页

作者： laura Siverio Martínez Mayra González Hurtado laura M.Castro González Jacques Rieumont Briones Ariel Martínez García María I.Hernández díaz Institute of Materials Science and Technology Polymer LaboratoryUniversity of HavanaZapata and GC.P.10400C.Havana CityCuba national Autonomous University of Mexico Department of Physical and Theoretical Chemistry CoyoacanDistrito FederalMX faculty of Chemistry University of HavanaDepartment of Physical ChemistryZapata and GC.P.10400Havana CityCuba Institute of Horticultural Research Liliana dimitrova Quivicánkm 33½.Havana CityCuba

fertilizers industry faces the challenge of improving the efficiency of its products either by optimizing the fertilizers in use or by developing new types of *** the last decade,controlled and slow release technologies have become more *** technologies aim to increase the efficiency of the applied substance by increasing its action over time and avoiding losses of all kinds(leaching,volatilization).The main purpose of the current study was to obtain a slow release biofertilizer by incorporating microalgae into a polymeric urea-formaldehyde matrix(PUfM).The quantitative analysis of macronutrients and micronutrients in the microalgae was determined using different techniques including titration,UV and Atomic Adsorption *** matrix and the formulation obtained(PUfM+CHLO)were also characterized by Infrared Spectroscopy(fTIR)and Scanning Electron Microscopy(SEM).The“in vitro”study showed a typical slow release behavior of nitrogen(N),phosphorus(P)and potassium(K)*** was also shown that(PUfM+CHLO)formulation has the slowest macronutrients release time with a maximum release of 28%,26%y 46%for(N-P-K)macronutrients respectively during a period of 30 ***"in vivo"study exposed the benefits of the biofertilizer formulation(PUfM+CHLO)from conventional commercial fertilizer(Cf)(NPK-14-5-12).due to the presence of nutrients of natural origin in microalgae,(PUfM+CHLO)shows ecological effects which could also developing sustainable agriculture systems.

关键词： Slow-release fertilizer microalgae polymeric matrix nutrients

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A modified intron of VRT2 drives glume and grain elongation in wheat

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Molecular Plant 2021年第9期14卷 1421-1423页

作者： laura E.dixon Scott A.Boden faculty of Biological Sciences University of LeedsLeeds LS29JTUK School of Agriculture Food and WineWaite Research InstituteUniversity of AdelaideGlen OsmondSA 5064Australia

Yield is a complex trait that is determined predominantly by the number,size,and weight of grain produced by a plant,which are all in fluenced by multiple genes and environ mental *** cereals,grain size is in flue need by envir on mental signals including nutrient availability and temperature,and by variation for genes that control the dimensions of a grain or the size of floral organs(e.g.,Heang and Sassa,2012;Brinton et al.,2017;Adamski et al.,2021;Liu et al.,2021;Xiao et al.,2021).Three recent studies have investigated subspecies of tetrapioid and hexapioid wheat that produce Ion ger grains,which form in florets that contain elongated floral structures(Adamski et al.,2021;Liu et al.,2021;Xiao et al.,2021);their findings provide new understanding of the genes controlling floret architecture,which could be used by breeders to enhance grain size and yield.

关键词： grain organs wheat

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Identification of QTL and underlying genes for root system architecture associated with nitrate nutrition in hexaploid wheat

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Journal of Integrative Agriculture 2022年第4期21卷 917-932页

作者： Marcus GRIffITHS Jonathan A.ATKINSON laura-Jayne GARdINER Ranjan SWARUP Michael P.POUNd Michael H.WILSON Malcolm J.BENNETT darren M.WELLS School of Biosciences University of NottinghamSutton Bonington CampusLE125RDUK future food Beacon of Excellence University of NottinghamSutton Bonington CampusLE125RDUK Integrative Phenomics Group School of BiosciencesUniversity of NottinghamSutton Bonington CampusLE125RDUK IBM Research The Hartree CentreWarringtonWA44ADUK School of Computer Science University of NottinghamNottinghamNG81BBUK

The root system architecture(RSA) of a crop has a profound effect on the uptake of nutrients and consequently the potential yield. However, little is known about the genetic basis of RSA and resource adaptive responses in wheat(Triticum aestivum L.). Here, a high-throughput germination paper-based plant phenotyping system was used to identify seedling traits in a wheat doubled haploid mapping population, Savannah×Rialto. Significant genotypic and nitrate-N treatment variation was found across the population for seedling traits with distinct trait grouping for root size-related traits and root distribution-related traits. Quantitative trait locus(QTL) analysis identified a total of 59 seedling trait QTLs. Across two nitrate treatments, 27 root QTLs were specific to the nitrate treatment. Transcriptomic analyses for one of the QTLs on chromosome 2 d, which was found under low nitrate conditions, revealed gene enrichment in N-related biological processes and 28 differentially expressed genes with possible involvement in a root angle response. Together, these findings provide genetic insight into root system architecture and plant adaptive responses to nitrate, as well as targets that could help improve N capture in wheat.

关键词： doubled-haploid population nitrate Rna-seq quantitative trait loci root system architecture Triticum aestivum L.(wheat)

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Gluten immunogenic peptide excretion detects dietary transgressions in treated celiac disease patients

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World Journal of Gastroenterology 2019年第11期25卷 1409-1420页

作者： Ana florencia Costa Emilia Sugai María de la Paz Temprano Sonia Isabel Niveloni Horacio Vázquez María laura Moreno M.Remedios domínguez-flores Alba Mu?oz-Suano Edgardo Smecuol Juan Pablo Stefanolo Andrea f González Angel Cebolla-Ramirez Eduardo Mauri?o Elena f Verdú Julio César Bai Small Bowel Section Department of MedicineDr.C.Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1263Argentina department of Immunology Biomedal S.L.Sevilla 41092Spain farncombe family digestive Health Research Institute McMaster UniversityHamiltonON L8S4L8Canada Research Institutes Universidad del SalvadorBuenos Aires 1050Argentina

BACKGROUNd Life-long removal of gluten from the diet is currently the only way to manage celiac disease(Ced). Until now, no objective test has proven useful to objectively detect ingested gluten in clinical practice. Recently, tests that determine consumption of gluten by assessing excretion of gluten immunogenic peptides(GIP) in stool and urine have been developed. Their utility, in comparison with conventional dietary and analytical follow-up strategies, has not been fully *** To assess the performance of enzyme-linked immunosorbent assay(ELISA) and point-of-care tests(PoCTs) for GIP excretion in Ced patients on gluten-free diet(Gfd).METHOdS We conducted an observational, prospective, cross-sectional study in patients following a Gfd for at least two years. Using the Gastrointestinal Symptom Rating Scale questionnaire, patients were classified at enrollment as asymptomatic or symptomatic. Gluten consumption was assessed twice by 3-d dietary recall and GIP excretion(by ELISA in stool and PoCTs(commercial kits for stool and urine) in two consecutive samples. These samples and dietary reports were obtained 10 day apart one from the other. Patients were encouraged to follow their usual Gfd during the study *** forty-four patients were enrolled, of which 19(43.2%) were symptomatic despite being on a Gfd. Overall, 83 sets of stool and/or urine samples were *** out of 44 patients(25.0%) had at least one positive GIP test. The occurrence of at least one positive test was 32% in asymptomatic patients compared with 15.8% in symptomatic patients. GIP was concordant with dietary reports in 65.9% of cases(Cohen′s kappa: 0.317). PoCT detected dietary indiscretions. Both ELISA and PoCT in stool were concordant(concomitantly positive or negative) in 67 out of 74(90.5%) samples. Excretion of GIP was detected in 7(8.4%) stool and/or urine samples from patients considered to be strictly compliant with the Gfd by dietary *** GIP dete

关键词： Celiac disease follow-up Gluten-free diet Gluten immunogenic peptide excretion Rapid tests

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Use of fe/Al drinking water treatment residuals as amendments for enhancing the retention capacity of glyphosate in agricultural soils

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Journal of Environmental Sciences 2015年第8期27卷 133-142页

作者： Yuanyuan Zhao laura A.Wendling Changhui Wang Yuansheng Pei The Key Laboratory of Water and Sediment Sciences Ministry of Education School of Environment Beijing Normal University School of Agriculture and food Sciences University of Queensland State Key Laboratory of Lake Science and Environment Nanjing Institute of Geography and Limnology Chinese Academy of Sciences

fe/Al drinking water treatment residuals（WTRs）, ubiquitous and non-hazardous by-products of drinking water purification, are cost-effective adsorbents for glyphosate. Given that repeated glyphosate applications could significantly decrease glyphosate retention by soils and that the adsorbed glyphosate is potentially mobile, high sorption capacity and stability of glyphosate in agricultural soils are needed to prevent pollution of water by ***, we investigated the feasibility of reusing fe/Al WTR as a soil amendment to enhance the retention capacity of glyphosate in two agricultural soils. The results of batch experiments showed that the fe/Al WTR amendment significantly enhanced the glyphosate sorption capacity of both soils（p 〈 0.001）. Up to 30% of the previously adsorbed glyphosate desorbed from the non-amended soils, and the fe/Al WTR amendment effectively decreased the proportion of glyphosate desorbed. fractionation analyses further demonstrated that glyphosate adsorbed to non-amended soils was primarily retained in the readily labile fraction（na HCO3-glyphosate）. The WTR amendment significantly increased the relative proportion of the moderately labile fraction（HCl-glyphosate） and concomitantly reduced that of the na HCO3-glyphosate, hence reducing the potential for the release of soil-adsorbed glyphosate into the aqueous phase. furthermore, fe/Al WTR amendment minimized the inhibitory effect of increasing solution p H on glyphosate sorption by soils and mitigated the effects of increasing solution ionic strength. The present results indicate that fe/Al WTR is suitable for use as a soil amendment to prevent glyphosate pollution of aquatic ecosystems by enhancing the glyphosate retention capacity in soils.

关键词： Glyphosate Soil amendment fe/Al drinking water treatment residuals Sorption capacity Stability

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Interaction of piRna-like sequences from the 3′-UTR of SARS-CoV-2 with mRna regions

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Genes & diseases 2023年第6期10卷 2282-2284页

作者： laura Pérez-Campos Mayoral María Teresa Hernández-Huerta Carlos Romero díaz Carlos Alberto Matias-Cervantes Eduardo Pérez-Campos Mayoral Margarito Martínez Cruz Juan de dios Ruiz-Rosado Edgar Gustavo Ramos Martínez Marco Antonio Sánchez Medina Eduardo Pérez-Campos Research Center Faculty of Medicine UNAM-UABJOAutonomous University“Benito Juárez”of Oaxaca(UABJO)Oaxaca 68020Mexico COnaCyT Faculty of Medicine and Surgery.Autonomous University“Benito Juárez”of Oaxaca(UABJO)Oaxaca 68020Mexico national Technology of Mexico(TecNM)/IT Oaxaca Oaxaca de JuárezOaxaca 68030Mexico The Research Institute at nationwide Children's Hospital Columbus 43205USA facultad de Química Universidad Nacional Autónoma de MéxicoCoyoacán 04510Mexico

Piwi-interacting Rnas(piRnas of 26-32 nt in length)regulate gene expression,epigenetics,and transcriptional and post-transcriptional processes.1 In humans,piRnas are expressed in germline and somatic tissues,and generally have a uracil at the 5'-end(position+1),an adenine at the+10 position,and are 2'-0 methylated at the 3'-end.2 Onice piRnas form the Rna-induced silencing complex(RISC)with PIWl proteins,they serve as guides to find their complementary sequences of the target mRna,thus initiating their *** Wuhan patient's genome is approximately 265 nucleotides(nts)in its 3'-UTR;piRnas-like sequences have been reported in this region.3 Our objective was to search,through bioinformatics,for mRna sequences that were homologous to the reverse complementary of the previously reported piRna-like sequences from the 3'-UTR of SARS-Cov-2,3 and identify the possible interaction between them.

关键词： sequences complementary initiating

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Ethylene-Propene Copolymerization with C1-symmetric ansa-fluorenyl-zirconocene Catalysts: Effects of Catalyst Structure and Comonomer on Molar Mass

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Chinese Journal of Polymer Science 2020年第3期38卷 220-230,I0005页

作者： Simona Losio laura Boggioni Massimiliano Cornelio Abbas Razavi Incoronata Tritto CNR–Istituto di Scienze e Tecnologie Chimiche"G.natta"(CNR-SCITEC) via Alfonso Corti 12-20133 MilanoItaly Total Petrochemicals Research Zone Industrielle CB-7181 FeluyBelgium

Ethylene-propene copolymers have been synthesized by three C1-symmetric metallocene molecules(1,2,and 3),having tert-butyl substituents on the Cp moiety,on the fluorenyl moiety,or on both moieties,and methylaluminoxane(MAO)at different polymerization temperatures and monomer *** were investigated by 13 C-NMR,1 H-NMR,and SEC analyses.A relationship was found between[EEE]/[E]ratios and copolymer molar masses in each series:the higher the[EEE]/[E]ratio,the lower the copolymer molar *** parity of[EEE]/[E]ratio,copolymer molar mass follows the order 1>>3>*** end group analysis reveals that copolymers mainly terminate when propene is the last inserted unit,confirming that it is the greater facility of Mt-P-E-poly(E-co-P)to terminate that influences the copolymer molar *** the catalysts considered,catalyst 1,which gives syndiospecific polypropene,gives greater activities,comonomer incorporation,and molar *** 3,which gives isospecific polypropene,in copolymerization performs better than 2,having the same bridge,with respect to activities,ethylene content,and molar *** good performance of this catalyst arises from the not necessity of polymer chain to back skip when ethylene is the last inserted unit.

关键词： Ethylene-propene Metallocene catalysts Copolymers Microstructure Molar masses

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Virtual drug design： Skpl-Skp2 inhibition targets cancer stem cells

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Asian Journal of Andrology 2013年第6期15卷 717-718页

作者： laura E Pascal Zhou Wang department of Urology University of Pittsburgh School of Medicine Pittsburgh PA 15232 USA University of Pittsburgh Cancer Institute University of Pittsburgh School of Medicine Pittsburgh PA 15232 USA department of Pharmacology and Chemical Biology University of Pittsburgh School of Medicine Pittsburgh PA 15232 USA

The dysregulation of pathways regulat-ing cellular function is a frequent hall-mark of cancer and the development of specific pathway inhibitors that alter tumor growth and progression are the focus of multiple recent studies. E3 ubiquitin ligases are a large group of diverse protein enzymes that specifically target proteins for dear- ance, and their importance to normal cel-lular function is illustrated in the many diseases associated with their loss of func- tion or inappropriate targeting. S-phase kinase-associated protein 2 （Skp2） is an f box protein that plays critical roles in cell-cycle progression, senescence, metabolism, and acts as an Skpl-Cullin-l-f box （SCf） ubiquitin ligase substrate recognition fac-tor. Overexpression of Skp2 is associated with poor prognosis and metastasis in many cancers and is a well validated drug target. In a recent report, Chart et al. have iden-tified an Skp2 inhibitor that selectively impairs Skp2 E3 ligase activity using an integrated virtual high-throughput drug screening and experimental validation approach. This Skp2 inhibitor restricts cancer stemness and potentiates sensitivity to chemotherapeutic agents in multiple ani-mal tumor models. These findings identify a new novel small molecule that targets the Skp2 and reduces tumor growth by attenu-ating aerobic glycolysis and inducing cel-lular senescence.

关键词： REGULATES AKT UBIQUITInaTION

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Elucidation of thermally induced internal porosity in zinc oxide nanorods

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nano Research 2018年第5期11卷 2412-2423页

作者： Albertus d. Handoko laura-Lynn Liew Ming Lin Gopinathan Sankar Yonghua du Haibin Su Zhili dong Gregory K. L. Goh Institute of Materials Research and Engineering Agency for Science Technology and Research (A＊STAR) Singapore 138634 Singapore School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore department of Chemistry University College London London WC1H0AJ UK Institute of Chemical and Engineering Sciences Agency for Science Technology and Research (A＊STAR) Singapore 627833 Singapore

In situ electron microscopy, tomography, photoluminescence, and X-ray absorption spectroscopy were utilized to monitor and explain the formation and growth of internal pores within ZnO nanorods. Careful examination using electron microscopy and tomography indicate that nanosized intemal pores start appearing within the individual solution-grown ZnO nanorods upon exposure to 200 ℃. The pore volume growth rate is proportional to the heat treatment time, indicating that the process is diffusion controlled, akin to a reverse Ostwald ripening-like process. A manageable pore growth rate of 1.4-4.4 nm^3·min^-1 was observed at 540 ℃, suggesting that the effective control over internal porosity can be achieved by carefully controlling the heat-treatment profile. Mechanistic studies using X-ray absorption spectroscopy indicated that the pore formation is linked to the significant reduction of the number of zinc vacancies after heat treatment. An optimum condition exists where most of the native surface defects are removed, while the bulk defects are contained within the internal pores. It is also demonstrated that the internal porosity can be exploited to improve the visible light absorption of ZnO. A combination of the lower defect density and improved light absorption of the heat-treated ZnO films thus lead to an increase in the photo- electrochemical response of more than 20× compared to that of the as-grown ZnO.

关键词： zinc oxide solution growth hydrothermal porosity photocatalysis photocurrent

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