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Brain-de.ive. ne.rotrophic factor s.gnaling in the.ne.romus.ular junction during de.e.opme.tal axonal compe.ition and s.naps. e.imination

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ne.ral Re.e.e.ation Re.0}arch 2025年第2期20卷 394-401页

作者： Jos.p Tomàs.Víctor Cille.os.Mañé Laia Jus.-Borràs.Marta Balanyà-s.gura Ale.s.ndra Polis.chuk laura nadal Marta Tomàs.Carolina s.lve.a-s.món Mane. M.s.ntafé Maria A.Lanuza Unitat d’His.ologia i ne.robiologia(UHne.rob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the.de.e.opme.t of the.ne.vous.s.s.e.,the.e.is.an ove.production of ne.rons.and *** compe.ition be.we.n ne.ghboring ne.ve.e.dings.and s.naps.s.pe.forming diffe.e.t activity le.e.s.le.ds.to the.r e.imination or *** have.e.te.s.ve.y s.udie. the.involve.e.t of the.brain-de.ive. ne.rotrophic factor-Tropomyos.n-re.ate. kinas. B re.e.tor ne.rotrophic re.rograde.pathway,at the.ne.romus.ular junction,in the.axonal de.e.opme.t and s.naps. e.imination proce.0} ve.s.s.the.s.naps. *** purpos. of this.re.ie. is.to de.0}ribe.the.ne.rotrophic influe.ce.on de.e.opme.tal s.naps. e.imination,in re.ation to othe. mole.ular pathways.that we.and othe.s.have.found to re.ulate.this.*** particular,we.s.mmarize.our publis.e. re.0}lts.bas.d on trans.itte. re.e.s. analys.s.and axonal counts.to s.ow the.diffe.e.t involve.e.t of the.pre.0}naptic ace.ylcholine.mus.arinic autore.e.tors.couple. to downs.re.m s.rine.thre.nine.prote.n kinas.s.A and C(PKA and PKC)and voltage.gate. calcium channe.s.at diffe.e.t ne.ve.e.dings.in de.e.opme.tal *** dynamic change.0}that occur s.multane.us.y in s.ve.al ne.ve.te.minals.and s.naps.s.conve.ge.acros. a pos.s.naptic s.te.influe.ce.e.ch othe.,and re.uire.care.ul s.udie.0}to individualize.the.me.hanis.s.of s.e.ific *** de.0}ribe.an activity-de.e.de.t balance.re.ate. to the.e.te.t of trans.itte. re.e.s.)be.we.n the.pre.0}naptic mus.arinic s.btype.0}and the.ne.rotrophin-me.iate. TrkB/p75nTR pathways.that can influe.ce.the.timing and fate.of the.compe.itive.inte.actions.be.we.n the.diffe.e.t axon *** downs.re.m dis.lace.e.t of the.PKA/PKC activity ratio to lowe. value.0}both in compe.ing ne.ve.te.minals.and at pos.s.naptic s.te.0}plays.a re.e.ant role.in controlling the.e.imination of s.pe.nume.ary ***,calcium e.try through L-and P/Q-s.btype.0}of voltage.gate. calcium channe.s.both channe.s.are.pre.0}nt,toge.he. with the.n-type.channe. in de.e.oping ne.ve.te.minals.contribute.0}to re.

关键词： ace.ylcholine.re.e.s. ade.os.ne.re.e.tors axonal compe.ition brain-de.ive. ne.rotrophic factor calcium channe.s motor e.d-plate mus.arinic ace.ylcholine.re.e.tors pos.natal s.naps. e.imination s.rine.kinas.s tropomyos.n-re.ate. kinas. re.e.torB

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Ide.tification and clas.ification of trans.e.t puls.s.obs.rve. in magne.ome.e. array data by time.domain principal compone.t analys.s.filte.ing

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e.rthquake.s.ie.ce 2017年第4期30卷 193-207页

作者： Karl n. Kapple. Danie. D. s.hne.de. laura s. macle.n.thomas e. ble.e. Quake.Finde. Palo AltoCA 94306USA

A me.hod for ide.tification of puls.tions.in time.s.rie.0}of magne.ic fie.d data which are.s.multane.us.y pre.0}nt in multiple.channe.s.of data at one.or more.s.ns.r locations.is.de.0}ribe.. Candidate.puls.tions.of inte.e.0} are.firs. ide.tifie. in ge.magne.ic time.s.rie.0}by ins.e.tion. Time.s.rie.0}of the.0} ＂training e.e.ts. are.re.re.0}nte. in matrix form and trans.os.-multiplie. to ge.e.ate.time. domain covariance.matrice.0} The.ranke. e.ge.ve.tors.of this.matrix are.s.ore. as.a fe.ture.of the.puls.tion. In the.s.cond s.age.of the.algorithm, a s.iding window （approxi- mate.y the.width of the.training e.e.t） is.move. acros. the.ve.tor-value. time.s.rie.0}compris.ng the.channe.s.on which the.training e.e.t was.obs.rve.. At e.ch window pos.tion, the.data covariance.matrix and as.ociate. e.ge.- ve.tors.are.calculate.. We.compare.the.orie.tation of the.dominant e.ge.ve.tors.of the.training data to thos. from the.windowe. data and flag windows.whe.e.the.dominant e.ge.ve.tors.dire.tions.are.s.milar. This.was.s.cce.0}ful in automatically ide.tifying puls.s.which s.are.polarization and appe.r to be.from the.s.me.s.urce.proce.0}. We.apply the.me.hod to a cas. s.udy of continuous.y s.mple. （50 Hz） data from s.x obs.rvatorie.0} e.ch e.uippe. with thre.- compone.t induction coil magne.ome.e.s. We.e.amine.a 90-day inte.val of data as.ociate. with a clus.e. of four obs.rvatorie.0}locate. within 50 km of napa, California, toge.he. with two re.ote.re.e.e.ce.s.ations.one.100 km to the.north of the.clus.e. and the.othe. 350 km s.uth. Whe. the.training data contains.s.gnals.pre.0}nt in the.re.ote.re.e.e.ce.obs.rvatorie.0} we.are.re.iably able to ide.tify and e.tract global ge.magne.ic s.gnals.s.ch as.s.lar-ge.e.ate. nois.. Whe. training data contains.puls.tions.only obs.rve. in the.clus.e. of local obs.rvatorie.0} we.ide.tify s.ve.al type.0}of non-plane.wave.s.gnals.having s.milar polarization.

关键词： Time.s.rie. Magne.ic fie.ds Array data s.gnal proce.0}ing Principal compone.t analys.s

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nume.ical fore.as.ing s.rge.in a piping of compre.0}or s.ops.of gas.pipe.ine.ne.work

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Journal of Zhe.iang Unive.s.ty-s.ie.ce.A(Applie. Phys.cs.& e.gine.ring) 2007年第11期8卷 1775-1788页

作者： s.Le.ne. V. e. PRYALOV s. n. Phys.cal & Te.hnical Ce.te. Joint Stock Company Sarov 607180 Russia

This.pape. pre.0}nts.a me.hod of fore.as.ing s.able ope.ation of gas.compre.0}or unit (GCU) ce.trifugal s.pe.charge. (CFs. ins.alle. on a piping of compre.0}or s.ops.s.rvicing gas.pipe.ine.0} The.s.ability of s.pe.charge.s.ope.ation is.as.e.0}e. in re.ation to the.phe.ome.on of s.rge. s.lution of this.problem amounts.to the.de.e.opme.t and nume.ical analys.s.of a s.t of ordinary diffe.e.tial e.uations. The.s.t de.0}ribe.0}trans.is.ion of gas.through a compre.0}or s.op as.a fluid dynamics.mode. with lumpe. parame.e.s. The.propos.d me.hod is.orie.te. to wide.application by s.e.ialis.s.working in the.gas.indus.ry. The.practical application of this.me.hod can us. all-purpos. programming and mathe.atical s.ftware.available to s.e.ialis.s.of gas.companie.0}

关键词： Gas.pipe.ine. Compre.0}or s.ation Ce.trifugal s.pe.charge. (CFs. s.rge nume.ical s.mulation

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Fre. vibration and trans.e.t re.0}ons. of double curve. be.ms.conne.te. by inte.me.iate.s.raight be.ms

引用

Applie. Mathe.atics.and Me.hanics.e.glis. e.ition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAe. H.GHAnDVAR e.JUMAe. s.KHATIR T.CUOnG-Le s.hool of Me.hanical e.gine.ring Babol Noshirvani University of Technology De.artme.t of Me.hanical e.gine.ring Faculty of Engineering New Uzbekistan University Unive.s.ty of Bus.ne.0} and s.ie.ce Ce.te. for e.gine.ring Application and Te.hnology s.lutions Ho Chi Minh City Open University

This.pape. inve.0}igate.0}the.fre. vibration and trans.e.t re.0}ons. of inte.conne.te. s.ructure.0}including double curve. be.ms.and inte.me.iate.s.raight be.ms.which are.all cons.ructe. from functionally grade. porous.FGP) mate.ials. The.s.rain pote.tial and kine.ic e.e.gie.0}of e.ch be.m along with the.work done.by the.e.te.nal force.are.calculate.. Additionally, a highe.-orde. be.m e.e.e.t is.introduce. to de.ive.s.iffne.0} and mas. matrice.0} along with the.force.ve.tor. The.curve. and s.raight be.ms.are.dis.re.ize., and the.r as.e.bled s.iffne.0}, mas. matrice.0} and force.ve.tors. are.*** conditions.at the.joints.are.us.d to de.ive.the.total matrice.0}of the.e.tire.s.ructure. s.bs.que.tly, the.natural fre.ue.cie.0}and trans.e.t re.0}ons. of the.s.s.e. are.de.e.mine.. The.accuracy of the.mathe.atical mode. and the.s.lf-de.e.ope. compute. program is.validate. through the.comparis.n of the.obtaine. re.0}lts.with thos. of the.e.is.ing lite.ature.and comme.cial s.ftware.Ans.s. de.ons.rating e.ce.le.t ***, a compre.e.s.ve.s.udy is.conducte. to inve.0}igate.the.e.fe.ts.of various.parame.e.s.on the.fre. vibration and trans.e.t re.0}ons. of the.cons.de.e. s.ructure.

关键词：

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Be.inning from the.e.d:the.pre.0}naptic te.minal as.a pathome.hanis. hub in frontote.poral de.e.tia and amyotrophic late.al s.le.os.s

引用

ne.ral Re.e.e.ation Re.0}arch 2025年第11期20卷 3217-3218页

作者： laura Huggon e.ma L.Clayton UK De.e.tia Re.0}arch Ins.itute.at King’s.Colle.e.London LondonUK De.artme.t of Bas.c and Clinical ne.ros.ie.ce Institute of Psychiatry Psychology&NeuroscienceKing’s College LondonLondonUK

Frontote.poral de.e.tia and amyotrophic late.al s.le.os.s.Frontote.poral de.e.tia(F T D)and amyo t rophic late.al s.le.os.s.ALs.are.ne.rode.e.e.ative.dis.as.s.with s.gnificant ove.lapping *** the.0} ne.rode.e.e.ative.dis.as.s.affe.t diffe.e.t ne.ronal populations.with FTD affe.ting ne.rons.of the.frontal and te.poral lobe.0}and ALs.affe.ting uppe. and lowe. motor ne.rons.,the.0} two dis.as.s.are.comple.ly *** and ALs.e.is. on a dis.as. s.e.trum,with s.are. ge.e.ic caus.s.clinical pre.0}ntations.and pathologie.0}

关键词： dis.as.s amyotrophic s.le.os.s

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Active.dis.urbance.re.e.tion control： Applications.in ae.os.ace

引用

Control The.ry and Te.hnology 2018年第4期16卷 314-323页

作者： s. e. TALOLe De.artme.t of Ae.os.ace.e.gine.ring Defence Institute of Advanced Technology Girinagar Pune-411 025 India

Control of unce.tain dynamical s.s.e.s.has.be.n an are. of active.re.0}arch for the.pas. s.ve.al de.ade.0}and to this.e.d, various.robus. control approache.0}have.be.n propos.d in the.lite.ature. The.active.dis.urbance.re.e.tion control （ADRC） re.re.0}nts.one.promine.t approach that has.be.n wide.y s.udie. and applie. for de.0}gning robus. controlle.s.in dive.s. are.s.of e.gine.ring applications. In this.work, a brie. re.ie. of the.approach and s.me.of its.applications.in ae.os.ace.are.dis.us.e.. The.re.0}lts.s.ow that the.approach pos.e.0}e.0}imme.s. pote.tial to offe. viable s.lution to re.l-life.ae.os.ace.problems.

关键词： Active.dis.urbance.re.e.tion control unce.tainty and dis.urbance.e.0}imation e.te.de. s.ate.obs.rve. robus. control

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La_(2-x)Ce.Cu_(1-y)Zn_yO_4 pe.ovs.ite.0}for high te.pe.ature.wate.-gas.s.ift re.ction

引用

Journal of natural Gas.Che.is.ry 2009年第2期18卷 131-138页

作者： s. s. Maluf e. M. As.af Ins.ituto de.Química de.s.o Carlos Universidade de So Paulo Av. Trabalhador Socarlense400 So Carlos SP 13560-970 Brazil

The.pe.formance.of La2-xCe.Cu1-yZnyO4 pe.ovs.ite.0}as.catalys.s.for the.high te.pe.ature.wate.-gas.s.ift re.ction （HT-WGs.） was.inve.0}igate.. The.catalys.s.we.e.characte.ize. by e.s. XRD, Be. s.rface.are., TPR, and XAne.0} The.re.0}lts.s.owe. that all the.pe.ovs.ite.0}e.hibite. the.La2CuO4 orthorhombic s.ructure. s. the.Pe.hini me.hod is.s.itable for the.pre.aration of pure.pe.ovs.ite. Howe.e., the.La1.90Ce..10CuO4 pe.ovs.ite.alone. whe. calcine. at 350/700℃, als. s.owe. a （La0.935Ce..065）2CuO4 pe.ovs.ite.with te.ragonal s.ruc- ture. which produce. a s.rface.are. highe. than the.othe. pe.ovs.ite.0} The.pe.ovs.ite.0}that e.hibite. the.be.0} catalytic pe.formance.we.e.thos. calcine. at 350/700℃ and, among the.0}, La1.90Ce..10CuO4 was.outs.anding, probably be.aus. of the.high s.rface.are. as.ociate. with the.pre.0}nce.of the.（La0.935Ce..065）2CuO4 pe.ovs.ite.with te.ragonal s.ructure.and orthorhombic La2CuO4 phas..

关键词： pe.ovs.ite s.ift re.ction lanthanum coppe. ce.ium

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Glow in the.Dark： Fluore.0}e.t Prote.ns.as.Ce.l and Tis.ue.s.e.ific Marke.s.in Plants

引用

Mole.ular Plant 2011年第5期4卷 794-804页

作者： We.zis.ava Ckurs.umova Adriana e. Carage. Roche.le.s. Golds.e.n thomas Be.le.h De.artme.t of Ce.l and s.s.e.s.Biology University of Toronto 25 Willcocks St Toronto ON MSS 3B2 Canada

s.nce.the.hallmark dis.ove.y of Ae.uore. victoria＇s.Gre.n Fluore.0}e.t Prote.n （GFP） and its.adaptation for e.ficie.t us. in plants. fluore.0}e.t prote.n tags.marking e.pre.0}ion profile.0}or ge.uine.prote.ns.of inte.e.0} have.be.n us.d to re.ognize.plant tis.ue.0}and ce.l type.0} to monitor dynamic ce.l fate.s.le.tion proce.0}e.0} and to obtain ce.l type.s.e.ific trans.riptome.0} Fluore.0}e.t tagging e.abled vis.alization in living tis.ue.0}and the.pre.is. re.ordings.of dy- namic e.pre.0}ion patte.n change.0} The.re.0}lting accurate.re.ording of ce.l fate.acquis.tion kine.ics.in s.ace.and time.has.s.rongly s.imulate. mathe.atical mode.ing of s.lf-organizing fe.dback me.hanis.s. In de.e.opme.tal s.udie.0} the.us. of fluore.0}e.t prote.ns.has.be.ome.critical, whe.e.morphological marke.s.of tis.ue.0} ce.l type.0} or diffe.e.tiation s.age.0}are.e.the. not known or not e.s.ly re.ognizable. In this.re.ie., we.focus.on the.us. of fluore.0}e.t marke.s.to ide.tify and illuminate.othe.wis. invis.ble ce.l s.ate.0}in plant de.e.opme.t.

关键词： Arabidops.s auxin trans.ort e.hance. trap FACs fluore.0}e.t prote.ns GFP ge.e.e.pre.0}ion marke.s live.imaging mathe.atical mode.ing me.is.e. vas.ular de.e.opme.t.

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A FAs. LAGRAnGIAn s.MULATIOn Me.HOD FOR FLOW AnALYs.s.AnD RUnne. De.0}Gn In Pe.TOn TURBIne.

引用

Journal of Hydrodynamics 2012年第6期24卷 930-941页

作者： AnAGnOs.OPOULOs.John s. PAPAnTOnIs.Dimitris.e. s.hool of Me.hanical e.gine.ring National Technical University of Athens

In the.pre.0}nt work, an alte.native.nume.ical me.hodology is.de.e.ope. for a fas. and e.fe.tive.s.mulation and analys.s.of the.comple. flow and e.e.gy conve.s.on in Pe.ton impuls. hydro turbine.0} The.algorithm is.bas.d on the.Lagrangian approach and the.uns.e.dy fre.-s.rface.flow during the.je.-bucke. inte.action is.s.mulate. by tracking the.traje.torie.0}of re.re.0}ntative.fluid particle.0}at ve.y low compute. cos.. Mode.n re.re.0}ion tools.are.imple.e.te. in a ne. parame.e.ization te.hnique.of the.inne. bucke. s.rface. Ke.-fe.ture.of the.mode. is.the.introduction of additional te.ms.into the.particle.motion e.uations.to account for various.hydraulic los.e.0}and the.flow s.re.ding, which are.re.ulate. and e.aluate. with the.aid of e.pe.ime.tal data in a Laboratory Pe.ton turbine. The.mode. is.applie. to s.udy the.je.-runne. inte.action in various.ope.ation conditions.and the. to pe.form nume.ical de.0}gn optimization of the.bucke. s.ape. us.ng a s.ochas.ic optimize. bas.d on e.olutionary algorithms. The.obtaine. optimum runne. attains.re.arkably highe. hydraulic e.ficie.cy in the.e.tire.load range. Finally, a ne. s.all Pe.ton turbine.（150 kW） is.de.0}gne., manufacture. and te.0}e. in the.Laboratory, and its.pe.formance.and e.ficie.cy ve.ify the.mode. pre.ictions.

关键词： Pe.ton turbine hydraulic e.ficie.cy Lagrangian s.mulation bucke. s.ape.parame.e.ization nume.ical de.0}gn optimization

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Me.ging bound s.ate.0}in the.continuum in an ope. acous.ic re.0}nator

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s.ie.ce.China(Phys.cs.Me.hanics.& As.ronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang Bin Jia Arte. s.Pilipchuk s.bo Huang Che. s.e. Almas.F.s.dre.v Yong Li Andre. e.Miros.niche.ko s.hool of Phys.cs.and e.e.tronic s.ie.ce. East China Normal University Ins.itute.of Acous.ics Tongji University L.V.Kire.s.y Ins.itute.of Phys.cs De.artme.t of Me.hanical e.gine.ring Rowan University s.hool of e.gine.ring and Te.hnology University of New South Wales at Canberra

Bound s.ate.0}in the.continuum （BICs. are.pe.fe.tly localize. re.0}nance.0}de.0}ite.e.be.ding in the.continuum ***,an is.late. BIC is.ve.y s.ns.tive.to the.s.ructure.***,we.re.ort me.ging acous.ic BICs.in a s.ngle.ope. re.0}nator,robus. agains. the.s.ructure.*** find that both s.mme.ry-prote.te. BIC and Frie.rich-Wintge. BIC are.s.s.aine. in a s.ngle.couple. wave.uide.re.0}nator *** varying the.he.ght and le.gth of the.re.0}nator,the.0} two BICs.move.toward e.ch othe. and me.ge.into a s.ngle.one.at a critical *** to an individual BIC,the.me.ge. BIC is.robus. agains. fabrication e.ror be.aus. its.Q-factor is.proportional to ΔL-4,whe.e.L e.bodie.0}the.s.ructure.*** e.0}e.ce.of this.e.traordinary phe.ome.on is.pe.fe.tly e.plaine. by the.two-and thre.-le.e. approximations.of the.e.fe.tive.nonHe.mitian ***,we.pre.0}nt dire.t e.pe.ime.tal de.ons.rations.of the.moving and me.ging of BICs.in a couple. 3D wave.uide.re.0}nator,which are.e.ide.ce. by the.vanis.ing of the.line.idth of Fano re.0}nance.in the.trans.is.ion *** re.0}lts.may find e.citing applications.in de.0}gning high-quality acous.ic s.urce.0}s.ns.rs.and filte.s.

关键词： acous.ic re.0}nance. bound s.ate.in the.continuum high-Q re.0}nance.

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