检索结果-南通市图书馆

Neural Regeneration Research 2019年第7期14卷 1217-1218页

作者： Cristina Angeloni laura Giusti Silvana Hrelia School of Pharmacy University of Camerino Department of Clinical and Experimental Medicine University of Pisa Department for Life Quality Studies Alma Mater Studiorum-University of Bologna

Neurodegenerative diseases are a heterogeneous group of disorders characterized by a progressive dysfunction and death of neural cells which lead to compromised motor or cognitive ***,the loss of neuron is associated with both gliosis and,frequently,with abnormal accumulation of extracellular and intracellular filamentous deposit in specific cell *** a rapidly increasing aging population,these diseases are becoming a primary health problem(Albers and Beal,2000).

关键词： New neuroprotective fighting oxidative

Goncrete block pavements in urban and local roads:Analysis of stress-strain condition and proposal for a catalogue

在线全文

学校读者我要写书评

暂无评论

Journal of Traffic and Transportation Engineering(English Edition) 2019年第6期6卷 557-566页

作者： Paola Di Mascio laura Moretti Americo Capannolo Department of Civil Building and Environmental EngineeringSapienza University of RomeRome 00184Italy

Although the construction of block pavements has grown fast in the last decades,there is still a need for simple tools that could be applied to design *** paper analyzed and verified concrete block pavements for urban and local roads composed of rectangular concrete pavers with plane side surfaces(no interlocking effect).The examined blocks were laid on a bedding sand layer,a cement treated base layer and a granular unbound foundation *** commercial finite element(FE)software ANSYS?was used to calculate the response of the pavement when subjected to different loading,construction *** wheel positions,five blocks patterns,three bedding sand thicknesses and joints gaps have been considered to evaluate stress-strain condition on pavement *** and rutting verification was performed respectively for bound and unbound pavement materials using analytical curves available in the *** the end of this study,a proposal for a catalogue is *** has nine pavement sets,because it takes into account three values of subgrade capacity(30,90,and 150 MPa of resilient modulus)and three levels of traffic(400,000,1,500,000,and 4,000,000 passages of commercial vehicles during the service life).The obtained results provide an inexpensive procedure for the preliminary design of concrete block pavements.

关键词： Block pavement Finite element model Concrete pavers Local roads Urban roads

Mutual Interference of Two Debris Flow Deposits Delivered in a Downstream River Reach

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2014年第6期11卷 1385-1395页

作者： STANCANELLI laura Maria LANZONI Stefano FOTI Enrico Department of Civil Engineering and Architecture University of Catania Department of Civil Environmental and Architectural Engineering University of Padua

We investigate experimentally the depositions of two contiguous debris flows flowing into a main river *** aim of the present experimental research is to analyze the geometry and the mutual interactions of debris flow deposits conveyed by these tributaries in the main channel.A set of 19 experiments has been conducted considering three values of the confluence angle,two slopes of the tributary,and three different triggering conditions(debris flows occurring simultaneously in the tributaries,or occurring first either in the upstream or in the downstream tributary).The flow rate along the main channel was always kept *** each experiment the two tributaries had the same slope and confluence *** analysis of the data collected during the experimental tests indicates that the volume of the debris fan is mainly controlled by the slope angle,as expected,while the shape of the debris deposit is strongly influenced by the confluence ***,in the case of multiple debris flows,the deposit shape is sensitive to the triggering *** index for damming formation available in literature has been considered and applied to the present case,and,on the basis of the collected data,considerations about possible extension of such indexes to the case of multiple confluences are finally proposed.

关键词： Debris flows Confluences Dam formation Triggering scenario Critical Index

A qualitative correlation between friction coefficient and steel surface wear in linear dry sliding contact to polymers with SGF

在线全文

学校读者我要写书评

暂无评论

Friction 2014年第1期2卷 47-57页

作者： Dorin RUS Lucian CAPITANU Liliana-laura BADITA Mechanical Department Institute of Civil EngineeringBucharest050153Romania Tribology Department Institute of Solid Mechanics of the Romanian AcademyBucharest010141Romania National Institute of Research and Development in Mechatronics and Measurement Technique Bucharest 0211631Romania

In this paper we tried to present a qualitative correlation,based on extensive experimental determinations between the value and the evolution of the friction coefficient,wear,and contact temperature,in the case of linear dry contact,for thermoplastic material reinforced with short glass fibers(SGF)and various steel *** aim was to highlight the evolution of the wear process depending on the evolution of the friction *** a result,it was possible to graphically illustrate the evolution of the friction coefficient and the change of the wear process,emphasizing the abrasive,adhesive and corrosive *** evolution of the plastic material transfer function of the contact temperature,namely of the power lost by friction(product between the contact pressure and sliding speed,p and v)was aimed and it was *** has been demonstrated that in the case of a 30%SGF content it can reach and even exceed contact temperatures very close to the flow limit of the plastic *** tried,believing successfully,the graphic illustration of the evolution of the steel surface wear and of the contact temperature,depending on the friction *** influence of the normal load and sliding speed was evaluated in detail,but also the influence of the metallic surface roughness on the friction coefficient was discussed.

关键词： friction coefficient evolution steel surface wear contact temperature plastic material transfer hardness of steel surface influence

Potential roles of functional bacterial amyloid proteins,bacterial biosurfactants and other putative gut microbiota products in the etiopathogeny of Parkinson’s Disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

BIOCELL 2021年第1期45卷 1-16页

作者： EMILIA MANOLE laura DUMITRESCU CRISTINA NICULIȚE BOGDAN OVIDIU POPESCU laura CRISTINA CEAFALAN Victor Babeș”National Institute of Pathology Bucharest050088Romania Colentina Clinical Hospital Bucharest020125Romania Carol Davila”University of Medicine and Pharmacy Bucharest020021Romania

An increasing number of studies provide evidence for the existence of a microbiota-gut-brain axis and its potential involvement in the development of sporadic Parkinson’s disease and other neurodegenerative *** neuropathologic hallmark of Parkinson’s disease is the presence of brain intraneuronal aggregates of misfolded alpha-synuclein,known as Lewy *** gut microbiota products may trigger alpha-synuclein conformational changes in the neurons of the enteric nervous system,which can then spread to the brain in a prion-like fashion through the vagus *** may interfere with neuroinflammatory pathways and susceptibility to *** this review,we assess the potential role of putative gut microbiota products in the etiopathogeny of Parkinson’s disease,with a special emphasis on functional bacterial amyloid proteins,bacterial biosurfactants,endotoxins and short-chain fatty *** possible roles of molecular hydrogen,a common byproduct of bacterial fermentation,are also addressed.

关键词： Alpha-synuclein Endotoxins Short-chain fatty acids

A modified intron of VRT2 drives glume and grain elongation in wheat

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2021年第9期14卷 1421-1423页

作者： laura E.Dixon Scott A.Boden Faculty of Biological Sciences University of LeedsLeeds LS29JTUK School of Agriculture Food and WineWaite Research InstituteUniversity of AdelaideGlen OsmondSA 5064Australia

Yield is a complex trait that is determined predominantly by the number,size,and weight of grain produced by a plant,which are all in fluenced by multiple genes and environ mental *** cereals,grain size is in flue need by envir on mental signals including nutrient availability and temperature,and by variation for genes that control the dimensions of a grain or the size of floral organs(e.g.,Heang and Sassa,2012;Brinton et al.,2017;Adamski et al.,2021;Liu et al.,2021;Xiao et al.,2021).Three recent studies have investigated subspecies of tetrapioid and hexapioid wheat that produce Ion ger grains,which form in florets that contain elongated floral structures(Adamski et al.,2021;Liu et al.,2021;Xiao et al.,2021);their findings provide new understanding of the genes controlling floret architecture,which could be used by breeders to enhance grain size and yield.

关键词： grain organs wheat

Chloride Ion Critical Content in Reinforced Concrete

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2007年第4期22卷 737-740页

作者：李岩 laura STIRNEMANN Materials and Structural Engineering Department Nanjing Hydraulic Research Institute University of Missouri-Rolla St.LouisMO63109USA

Chloride ion critical content was studied under soaking and cycle of dry and wet conditions, with three electrochemical nondestructive measuring techniques, i e, half-cell potential, A C impedance, and time potential. The experimental results show that chloride ion critical content is primarily determined by the water cement ratio, while for the same concrete mixture the chloride ion critical content in soaking conditions is larger than that in a cycle of dry and wet conditions.

关键词： chloride ion cycle of dry and wet critical content A C impedance

Noise-induced hippocampal damage:potential mechanisms

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第3期17卷 563-564页

作者： Sonia Jazmín Molina laura Ruth Guelman Universidad de Buenos Aires Consejo Nacional de Investigaciones Científicas y TécnicasCentro de Estudios Farmacológicos y Botánicos(CEFyBOUBA-CONICET)Facultad de MedicinaBuenos AiresArgentina Universidad de Buenos Aires Facultad de Medicina1^(a) Cátedra de FarmacologíaBuenos AiresArgentina

Exposure to noise of high intensities(> 80 dB) is considered a stressful event and might produce both auditory and extra-auditory damage,including different central nervous system(CNS) *** the CNS,the hippocampus(HC),a structure related to several cognitive functions,has shown to be particularly susceptible to the effects of noise.

关键词： damage auditory injuries

Sensors, Biosensors, and Analytical Technologies for Aquaculture Water Quality

在线全文

学校读者我要写书评

暂无评论

Research 2020年第1期2020卷 1521-1535页

作者： Xiaodi Su laura Sutarlie Xian Jun Loh Institute of Materials Research and Engineering Agency for ScienceTechnology and Research2 Fusionopolis Way.Innovis#08-03Singapore 138634 Department of Chemistry National University of SingaporeBlock S8Level 33 Science Drive 3Singapore 117543

In aquaculture industry,fish,shellfish,and aquatic plants are cultivated in fresh,salt,or brackish *** increasing demand of aquatic products has stimulated the rapid growth of aquaculture *** to effectively monitor and control water quality is one of the key concerns for aquaculture industry to ensure high productivity and high *** are four major categories of water quality concerns that affect aquaculture cultivations,namely,(1)physical parameters,e.g.,pH,temperature,dissolved oxygen,and salinity,(2)organic contaminants,(3)biochemical hazards,e.g.,cyanotoxins,and(4)biological contaminants,i.e.,*** the physical parameters are affected by climate changes,the latter three are considered as environmental *** this review,we provide a comprehensive summary of sensors,biosensors,and analytical technologies available for monitoring aquaculture water *** include low-cost commercial sensors and sensor network setups for physical *** also include chromatography,mass spectrometry,biochemistry,and molecular methods(e.g.,immunoassays and polymerase chain reaction assays),culture-based method,and biophysical technologies(e.g.,biosensors and nanosensors)for environmental contamination *** to the different levels of sophistication of various analytical techniques and the information they can provide(either fine fingerprint,highly accurate quantification,semiquantification,qualitative detection,or fast screening),we will comment on how they may be used as complementary tools,as well as their potential and gaps toward current demand of real-time,online,and/or onsite detection.

关键词： qualitative latter Quality

Effect of insoluble materials on the volumetric behavior of rock salt

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2021年第1期13卷 84-97页

作者： Mejda Azabou Ahmed Rouabhi laura Blanco-Martìn MINES ParisTech PSL Research UniversityCentre de Géosciences35 rue St HonoréFontainebleau77300France

This paper focuses on the presence of nodules of insoluble materials within salt specimens,and their effect on the volumetric strain measurements and the dilatancy *** analyzed experimental results of over 120 conventional triaxial compression tests,and found that in 20%of the cases,the volumetric strain measurements were *** also noted that the natural variability of the specimens can lead to a non-negligible data scattering in the volumetric strain measurements when different specimens are subjected to the same *** is expected given the small magnitude of those strains,but it occasionally implies that the corresponding specimens are not representative of the volumetric behavior of the studied *** order to understand these results,we numerically investigated salt specimens modeled as halite matrices with inclusions of *** of triaxial compression tests on these structures proved that such heterogeneities can induce dilatancy,and their presence can lead to the appearance of tensile zones which is physically translated into a micro-cracking *** modeling approach is validated as the patterns displayed in the numerical results are identical to that in the *** was then employed to explain the observed irregularities in experimental *** studied the natural variability effect as well and proposed a methodology to overcome the issue of specimen representativity from both deviatoric and volumetric perspectives.

关键词： Rock salt Dilatancy Material heterogeneity Natural variability Triaxial tests Virtual laboratory