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Major liver resections,perioperative issues and posthepatectomy liver failure:A comprehensive update for the anesthesiologist

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World Journal of Critical Care Medicine 2024年第2期13卷 49-71页

作者： Andrea De Gasperi laura Petrò Ombretta Amici Ilenia Scaffidi Pietro Molinari Caterina Barbaglio Eva Cibelli Beatrice Penzo Elena Roselli Andrea Brunetti Maxim Neganov Alessandro Giacomoni Paolo Aseni Elena Guffanti Former Head Anesthesia and Critical Care Service 2Grande Ospedale Metropolitano Niguarda ASST GOM NiguardaMilan 20163Italy AR1 Ospedale Papa Giovanni 23Bergamo 24100Italy Anesthesia and Critical Care Service 2 Grande Ospedale Metropolitano Niguarda AR2ASST GOM NiguardaMilan 20163Italy Anestesia e Terapia Intensiva Generale Istituto Clinico HumanitasRozzano 20089Italy Chirurgia Oncologica Miniinvasiva Grande Ospedale Metropolitano Niguarda ASST GOM NiguardaMilan 20163Italy Dipartimento di Medicina d’Urgenza ed Emergenza Grande Ospedale Metropolitano Niguarda ASST GOM NiguardaMilano 20163MIItaly

Significant advances in surgical techniques and relevant medium-and long-term outcomes over the past two decades have led to a substantial expansion in the indications for major liver *** support these outstanding results and to reduce perioperative complications,anesthesiologists must address and master key perioperative issues(preoperative assessment,proactive intraoperative anesthesia strategies,and implementation of the Enhanced Recovery After Surgery approach).Intensive care unit monitoring immediately following liver surgery remains a subject of active and often unresolved *** postoperative complications,posthepatectomy liver failure(PHLF)occurs in different grades of severity(A-C)and frequency(9%-30%),and it is the main cause of 90-d postoperative ***,recently redefined with pragmatic clinical criteria and perioperative scores,can be predicted,prevented,or *** review highlights:(1)The systemic consequences of surgical manipulations anesthesiologistsmust respond to or prevent,to positively impact PHLF(a proactive approach);and(2)the maximal intensivetreatment of PHLF,including artificial options,mainly based,so far,on Acute Liver Failure treatment(s),to buytime waiting for the recovery of the native liver or,when appropriate and in very selected cases,toward *** a clinical context requires a strong commitment to surgeons,anesthesiologists,and intensivists towork together,for a fruitful collaboration in a mandatory clinical continuum.

关键词： Liver resection Chronic liver disease Preoperative assessment Vascular clamping Intraoperative hemodynamic monitoring Postoperative intensive care unit Posthepatectomy liver failure Artificial liver support

Extravasated contrast volumetric assessment on computed tomography angiography in gastrointestinal bleeding:A useful predictor of positive angiographic findings

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World Journal of Radiology 2024年第5期16卷 115-127页

作者： laura Maria Cacioppa Chiara Floridi Alessandra Bruno NicolòRossini Tommaso Valeri Alessandra Borgheresi Riccardo Inchingolo Francesco Cortese Giacomo Novelli Alessandro Felicioli Mario Torresi Pietro Boscarato Letizia Ottaviani Andrea Giovagnoni Division of Interventional Radiology Department of Radiological SciencesUniversity Politecnica Delle MarcheAncona 60126Italy Department of Clinical Special and Dental SciencesUniversity Politecnica Delle MarcheAncona 60126Italy Division of Radiology Department of Radiological SciencesUniversity Hospital"Azienda Ospedaliero Universitaria Delle Marche"Ancona 60126Italy Interventional Radiology Unit "F Miulli"Regional General HospitalAcquaviva delle Fonti 70021Italy Department of Radiology IRCCS INRCAAncona 60126Italy

BACKGROUND Gastrointestinal bleeding(GIB)is a severe and potentially life-threatening condition,especially in cases of delayed *** tomography angiography(CTA)plays a pivotal role in the early identification of upper and lower GIB and in the prompt treatment of the *** To determine whether a volumetric estimation of the extravasated contrast at CTA in GIB may be a predictor of subsequent positive angiographic *** In this retrospective single-centre study,35 patients(22 men;median age 69 years;range 16-92 years)admitted to our institution for active GIB detected at CTA and further submitted to catheter angiography between January 2018 and February 2022 were ***-three(65.7%)patients underwent endoscopy before *** volumetry was evaluated in both arterial and venous phases via a semi-automated dedicated *** rate was obtained from volume change between the two phases and standardised for unit *** were divided into two groups,according to the angiographic signs and their concordance with *** Upper bleeding accounted for 42.9%and lower GIB for 57.1%.Mean haemoglobin value at the admission was 7.7 g/dL.A concordance between positive CTA and direct angiographic bleeding signs was found in 19(54.3%)*** no significant differences in terms of bleeding volume in the arterial phase(0.55 mL vs 0.33 mL,P=0.35),a statistically significant volume increase in the venous phase was identified in the group of patients with positive angiography(2.06 mL vs 0.9 mL,P=0.02).In the latter patient group,a significant increase in bleeding rate was also detected(2.18 mL/min vs 0.19 mL/min,P=0.02).CONCLUSION In GIB of any origin,extravasated contrast volumetric analysis at CTA could be a predictor of positive angiography and may help in avoiding further unnecessary procedures.

关键词： Gastrointestinal haemorrhage Computed tomography angiography Volumetric analysis Computer-assisted image interpretation Therapeutic embolization Transcatheter arterial embolization

Some Univalence Conditions for a General Integral Operator

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Chinese Annals of Mathematics,Series B 2012年第6期33卷 801-806页

作者： laura STANCIU Daniel BREAZ Department of Mathematics University of Pitesti Department of Mathematics University of Alba Iulia

The authors consider the classes of the univalent functions denoted by SH(β),SP and SP(α,β).On these classes,the univalence conditions for a general integral operator are studied.

关键词： Analytic function Integral operator Univalence condition GeneralSchwarz lemma

Hierarchical state-abstracted and socially augmented Q-Learning for reducing complexity in agent-based learning

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控制理论与应用（英文版） 2011年第3期9卷 440-450页

作者： laura RAY Thayer School of Engineering Dartmouth College

A primary challenge of agent-based policy learning in complex and uncertain environments is escalating computational complexity with the size of the task space(action choices and world states) and the number of ***,there is ample evidence in the natural world that high-functioning social mammals learn to solve complex problems with ease,both individually and *** ability to solve computationally intractable problems stems from both brain circuits for hierarchical representation of state and action spaces and learned policies as well as constraints imposed by social *** biologically derived mechanisms for state representation and mammalian social intelligence,we constrain state-action choices in reinforcement learning in order to improve learning *** results bound the reduction in computational complexity due to stateion,hierarchical representation,and socially constrained action selection in agent-based learning problems that can be described as variants of Markov decision *** of two task domains,single-robot herding and multirobot foraging,shows that theoretical bounds hold and that acceptable policies emerge,which reduce task completion time,computational cost,and/or memory resources compared to learning without hierarchical representations and with no social knowledge.

关键词： Decentralized Markov decision process Reinforcement learning Multiagent systems

Modeling the methyldiethanolamine-piperazine scrubbing system for CO2 removal： Thermodynamic analysis

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Frontiers of Chemical Science and Engineering 2016年第1期10卷 162-175页

作者： Stefania Moioli laura A. Pellegrini Dipartimento di Chimica Materiali e Ingegneria Chimica 'G. Natta' Politecnico di Milano Piazza Leonardo da Vinci 32 1-20 33 Milano Italy

Aqueous solutions of methyldiethanolamine （MDEA） and piperazine （PZ） are commonly used solvent nowadays. In this work a thermodynamic analysis with the Electrolyte-NRTL model has been performed for systems composed of acidic gases and MDEA＋ PZ aqueous solution. ASPEN Plus＇s has been used for thermodynamic modeling. Values of binary interaction parameters for liquid phase activity coefficients have been estimated from regressions of experimental data. Moreover, the influence of the interactions between ion pairs and MDEA or PZ molecular species has been analyzed. The final aim is to obtain a reliable tool for design and simulation of absorption and stripping columns, fundamentals also in order to carry out energy saving studies.

关键词： vapor-liquid equilibrium methyldietanola- mine piperazine regression Electrolyte-NRTL

Environmental parameters assessment of a new diffuser for air cooling/heating system:Measurements and numerical validation

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Building Simulation 2022年第6期15卷 1111-1132页

作者： Fabio Nardecchia laura Pompei Fabio Bisegna Department of Astronautic Electric and Energy EngineeringSapienza UniversityVia Eudossiana 18RomeItaly

Air distribution of HVAC systems is the most popular type used in the building sector,having a relevant impact on indoor air quality and occupant *** types of research developed optimal solutions for the HVAC system’s design,focusing on specific components of the distribution system,on the airflow and geometry of ducts,on the size of ducts,on the shape and position of air ***,few works in literature proposed a globally experimental and simulation analysis of an air distribution system with a variable mass flaw *** this line,the presented research investigates the potentialities of a new ceiling diffuser,installed in an exhibition *** system provides a variable mass flow rate thanks to its configuration,providing adequate thermal comfort.A warm wall is chosen as the heating *** tests are carried out,six for cooling and two for heating with different volumetric air rates and supply air temperature of the *** combination of two methods,the measurement campaigns and the computational fluid dynamics(CFD)technique represent a suitable approach to examine the thermal indoor *** general,results show a strong capability of this diffuser to provide a uniform temperature and velocity field inside the ***,experimental and numerical data are significantly comparable with an average deviation of 1%for the velocity and lower 1%for the temperature,guaranteeing an optimal distribution of the understudy environmental parameters on the vertical and horizontal planes.

关键词： environmental parameters CFD field measurements INDULINE HVAC systems thermal comfort

Algorithms to Compute the Largest Invariant Set Contained in an Algebraic Set for Continuous-Time and Discrete-Time Nonlinear Systems

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IEEE/CAA Journal of Automatica Sinica 2020年第1期7卷 57-69页

作者： laura Menini Corrado Possieri Antonio Tornambè Dipartimento di Ingegneria Industriale Universitàdi Roma Tor VergataRoma 00133Italy Istituto di Analisi dei Sistemi ed Informatica“A.Ruberti ”Consiglio Nazionale delle Ricerche(IASI-CNR)Roma 00185Italy Dipartimento di Ingegneria Civile e Ingegneria Informatica Universitàdi Roma Tor VergataRoma 00133Italy

In this paper, some computational tools are proposed to determine the largest invariant set, with respect to either a continuous-time or a discrete-time system, that is contained in an algebraic set. In particular, it is shown that if the vector field governing the dynamics of the system is polynomial and the considered analytic set is a variety, then algorithms from algebraic geometry can be used to solve the considered problem. Examples of applications of the method(spanning from the characterization of the stability to the computation of the zero dynamics) are given all throughout the paper.

关键词： Asymptotic stability discrete-time systems invariance nonlinear systems

Cognitive impairment in heart failure patients

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Journal of Geriatric Cardiology 2014年第4期11卷 316-328页

作者： laura Leto Mauro Feola School of Geriatry University of Turin Italy Cardiovascular Rehabilitation Heart Failure Unit Ospedale SS Trinita ' Via Ospedale 4-12045 Fossano Italy

Cognitive damage in heart failure （HF） involves different domains thus interfering with the ability for single patient to self-care and to cope with treatment regimens, modifying symptoms and health behaviours. Many cerebral and functional changes were detected in brain imaging, involving areas of both grey and white matter deputed to cognition. Although various instruments are available to explore cognition, no consensus was obtained on better tools to be used in HF population. Reduction in cerebral blood flow, decreased cardiac output, altera-tions of cerebrovascular reactivity and modification of blood pressure levels are the main features involved in the etiopathogenetic mecha-nisms of cognitive deficit. Several cardiac variables, laboratory parameters, demographic and clinical elements were studied for their possible relation with cognition and should be properly evaluated to define patients at increased risk of impairment. The present review gathers avail-able data pointing out assured information and discussing possible areas of research development.

关键词： Heart failure Cognitive impairment Blood pressure

Global wild rice germplasm resources conservation alliance:World Wild-Rice Wiring

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Molecular Plant 2024年第4期17卷 516-518页

作者： Xiaoming Zheng Disna Ratnasekera Jiayu Fan Robert J.Henry Beng-Kah Song Kenneth M.Olsen Bal Krishna Joshi Maria Celeste N.Banaticla-Hilario Tonapha Pusadee Adane Getachew Melaku Yeyinou laura Estelle Loko Koukham Vilayheuang Gavers K.Oppong Samuel Aduse Poku Peterson W.Wambugu Song Ge Aldo Merotto Junior Ohn Mar Aung Ramaiah Venuprasad Ajay Kohli Wenbin Zhou Qian Qian National Key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Sanya National Research Institute of Breeding in Hainan Chinese Academy of Agricultural SciencesBeijing 100081China International Rice Research Institute DAPO Box 7777Metro Manila 4031Philippines Department of Agricultural Biology Faculty of AgricultureUniversity of RuhunaMatara 81000Sri Lanka Yazhouwan National Laboratory No.8 Huanjin RoadYazhou DistrictSanya CityHainan Province 572024China Hainan University Haikou 570228China ARC Centre of Excellence for Plant Success in Nature and Agriculture University of QueenslandBrisbaneQLD4072Australia School of Science Monash University Malaysia47500 Bandar SunwaySelangor 47500Malaysia Department of Biology Washington University in St.LouisSt.LouisMO 63130-4899USA National Agriculture Genetic Resources Center(Genebank) KhumaltarPO Box 3055KathmanduNepal Plant Biology Division Insttute of Biological SciencesUniversity of the Pilippines Los BanosLos BanosLaguna 4031Philippines Division of Agronomy Department of Plant and Soil SciencesFaculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Bio and Emerging Technology Institute Addis Ababa 1165Ethiopia National University of Sciences TechnologiesEngineering and Mathematics(UNSTIM)Dassa-ZouméBP 14Benin National Genebank Rice and Cash Crops Research CenterNAFRIVientiane 0605Lao PDR Plant Sciences and the Bioeconomy Rothamsted ResearchHarpenden AL52JQUK UK Future Food Beacon of Excellence and School of Biosciences and University of Nottingham Nottingham LE125RDUK Department of Plant and Environmental Biology University of GhanaAccraGhana Kenya Agricultural and Livestock Research Organization Genetic Resources Research InstituteNairobi 00200Kenya Institute of Botany Chinese Academy of SciencesBeijing 100093China Federal University of Rio Grande do Sul UFRGSPorto Alegre 91501-970RSBrazil Department of Agricultur

Wild relatives of crop are key genetic resources serving as diversity reservoirs for crop improvement under changing ***(Oryza sativa)is one of the most important crops in the world,providing staple food for half of the world's *** rice is thus a critical germplasm resource for sustained global food security,ensuring high production yields,improved quality,and stress resistance in the face of climate *** rice is closely related to domesticated rice and has a rich genetic diversity and exceptional adaptability to extreme *** has played a pivotal role in the history of rice hybridization and has become a key resource for rice breeding *** identification of wild-type cytoplasmic male sterility resources paved the way for the achievement of the“three lines”goal in hybrid rice,leading to a significant increase in rice *** addition,the use of resistance alleles found in wild rice is making rice production more resilient to losses caused by environmental ***,wild rice germplasm resources are threatened due to habitat destruction and other anthropogenic *** the same time,the lack of centralized distribution of wild rice has hampered the sharing of basic information on wild rice resources and the utilization and conservation of wild rice in each country,as well as collaboration among scientists.

关键词： germplasm breeding crops