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World Journal of Gastroenterology 2015年第12期21卷 3554-3563页

作者： Xue-Xiu Zhang Li-Feng Wang Lei Jin Yuan-Yuan Li Shu-Li Hao Yan-Chao Shi Qing-Lei Zeng Zhi-Wei Li Zheng Zhang George kk lau Fu-Sheng Wang The Institute of Translational Hepatology 302 Military Hospital of China-Peking University Teaching Hospital Research Center for Biological Therapy Beijing 302 Hospital Non-Infectious Liver Disease Diagnosis and Treatment Center 302 Military Hospital of China-Peking University Teaching Hospital Research Center for Liver Transplantation 302 Military Hospital of China-Peking University Teaching Hospital Department for Hepatobiliary Surgery Beijing 302 Hospital

AIM: To investigate the incidence, characteristics, and risk factors for hepatocellular carcinoma(HCC) in Chinese patients with primary biliary cirrhosis(PBC).METHODS: We reviewed the data of 52 PB Cassociated HCC patients treated at Beijing 302 Hospital from January 2002 to December 2013 and analyzed its incidence and characteristics between the two genders. The risk factors for PBC-associated HCC were analyzed via a case-control study comprising 20 PBC patients with HCC and 77 matched controls without HCC. The matched factors included gender, age, follow-up period and Child-Pugh scores. Conditional logistic regression was used to evaluate the odds ratios of potential risk factors for HCC development. A P < 0.05 was considered statistically significant. RESULTS: The incidence of HCC in Chinese PBC patients was 4.13%(52/1255) and was significantly higher in the males(9.52%) than in the females(3.31%). Among the 52 PBC patients with HCC, 55.76%(29/52) were diagnosed with HCC and PBC simultaneously, and 5.76%(3/52) were diagnosed with HCC before PBC. The males with PBC-associated HCCwere more likely than the females to have undergone blood transfusion(18.75% vs 8.33%, P = 0.043), consumed alcohol(31.25% vs 8.33%, P = 0.010), smoked(31.25% vs 8.33%, P = 0.010), had a family history of malignancy(25% vs 5.56%, P = 0.012), and had serious liver inflammation, as indicated by the elevated levels of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and γ-glutamyl transpeptidase(P < 0.05). Conditional logistic regression analysis revealed that body mass index(BMI) ≥ 25 [adjusted odds ratio(AOR) = 1.116, 95%CI: 1.002-1.244, P = 0.045] and history of alcohol intake(AOR = 10.294, 95%CI: 1.108-95.680, P = 0.040) were significantly associated with increased odds of HCC development in PBC patients. CONCLUSION: HCC is not rare in Chinese PBC patients. Risk factors for PBC-associated HCC include BMI ≥ 25 and a history of alcohol intake. In addition to regul

关键词： Primary biliary cirrhosis Hepatocellular carcinoma

缺血性脑卒中患者诊间血压变异性对长期预后的影响

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中华高血压杂志 2015年第5期23卷 498-498页

作者： lau kk Wong YK Teo KC Chang RS Chan KH Hon SF Wat KL Cheung RT Li LS Siu CW Tse HF

血压变异性（blood pressure variablity，BPV）是动脉粥样硬化疾病发展的新的危险因素。最近研究显示，高BPV能预测腔隙性梗死患者的全因和心血管死亡率。除因小血管阻塞造成的脑卒中患者外，BPV是否对缺血性脑卒中患者的预后产生影响... 详细信息

血压变异性（blood pressure variablity，BPV）是动脉粥样硬化疾病发展的新的危险因素。最近研究显示，高BPV能预测腔隙性梗死患者的全因和心血管死亡率。除因小血管阻塞造成的脑卒中患者外，BPV是否对缺血性脑卒中患者的预后产生影响仍然不清楚。

关键词：脑卒中患者血压变异性长期预后缺血性动脉粥样硬化心血管死亡率腔隙性梗死危险因素

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Theoretical analysis of PAM-N and M-QAM BER computation with single-sideband signal

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Science China(Information Sciences) 2021年第8期64卷 172-181页

作者： Dongxu LU Xian ZHOU Yuqiang YANG Jiahao HUO Jinhui YUAN Keping LONG Changyuan YU Alan Pak Tao lau Chao LU Beijing Engineering and Technology Research Center for Convergence Networks and Ubiquitous Services University of Science and Technology Beijing Department of Electrical Engineering The Hong Kong Polytechnic University Department of Electronic and Information Engineering The Hong Kong Polytechnic University

In this paper, the theoretical bit error rate(BER) of N-level pulse amplitude modulation(PAMN)and M-ary quadrature amplitude modulation(M-QAM) have been studied and compared under different scenarios, including(i) PAM with intensity modulation with direct detection(IM/DD) and field modulation with detection(FMD)(including coherent detection and single-sideband modulation with direct detection(SSB-DD)), and(ii) QAM with coherent detection and SSB-DD. Considering the relationship between the symbol spacing and signal-to-noise ratio(SNR), we provide the mathematical BER equations, including the optical signal-to-noise ratio(OSNR) and carrier-to-signal power ratio(CSPR), especially for PAM *** verify the validity of our theoretical expressions for SSB systems, transmissions with 224-Gb/s SSBPAM4/16 QAM signals using the Kramers-Kronig(kk) receiver were implemented on a unified optical system platform. The simulation results agreed well with theoretical calculations both in back-to-back(BtB) and120-km transmission scenarios, which showed that the BER evaluation methods can serve as a theoretical guidance and system assessment criteria for SSB scenarios.

关键词： N-level pulse amplitude modulation(PAM-N) M-ary quadrature amplitude modulation(MQAM) BER computation single-sideband(SSB) Kramers-Kronig receiver

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35例肾移植并发症的报告

中华肾脏病杂志 1985年第4期01卷 21-26页

作者：陈文岩黄国基杨再杰李文骥刘允怡王树航 Hawkins B. 香港大学外科香港大学内科玛丽医院病理部香港政府玛丽医院外科部

本文报导了35例肾移植的并发症。外科并发症有:手术伤口感染、肾静脉血栓形成、输尿管瘘和管状淋巴管瘤等;内科并发症有血液学异常、高血压、肝功能异常及感染等。感染是一严重问题, 病毒感染以带状疱疹为最常见, 对Acyclovir有良效。... 详细信息

本文报导了35例肾移植的并发症。外科并发症有:手术伤口感染、肾静脉血栓形成、输尿管瘘和管状淋巴管瘤等;内科并发症有血液学异常、高血压、肝功能异常及感染等。感染是一严重问题, 病毒感染以带状疱疹为最常见, 对Acyclovir有良效。由于慢性排斥移植肾功能有明显衰退的病人, 改用环胞素A, 效果并不理想。HBsAg携带者及系膜1gA肾炎病者并非活体亲属肾移植的绝对禁忌症。本文35例均无死亡, 移植肾存活率第一年为91%。

关键词：肾移植/副作用手术后并发症

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国际妇产科超声学会早孕期胎儿超声指南

妇产与遗传(电子版) 2014年第3期4卷 54-64页

作者： L.J.Salomon Z.Alfirevic C.M.Bilardo G.E.Chalouhi T.Ghi K.O.Kagan T.K.lau A.T.Papageorghiou N.J.Raine-Fenning J.Stirnemann S.Suresh A.Taborl I.E.Timor-Tritsch A.Toi G.Yeo 杨芳梁国贤 Department of Obstetrics and Fetal Medicine and SFAPE(Societe Francaise d' Ameliorationdes Pratiques Echographique) Paris Descartes UniversityAssistance Publique-Hopitaux de ParisHopital Necker Enfants Department for Women' s and Children's Health University of Liverpool Fetal Medicine Unit Department of Obstetrics and GynaecologyUniversity Medical Centre Groningen Department of Obstetrics and Gynaecology Policlinico S.Orsola-MalpighiUniversity of Bologna Department of Obstetrics and Gynecology University of Tuebingen Fetal Medicine Centre Paramount ClinicCentral 7. Fetal Medicine UnitSt George' sUniversity of London 8. Division of Obstetrics & GynaecologySchool of Clinical SciencesUniversity of Nottingham 9. Obstetrics and Fetal MedicineGHU Necker-Enfants MaladesUniversity Paris Descartes 10. Mediscan Systems&Fetal Care Research Foundation 11. Fetal Medicine UnitDepartment of ObstetricsRigshospitaletCopenhagen University Hospital 12. Department of Obstetrics and GynecologyNew York University School of Medicine 13. Medical Imaging andObstetrics and GynaecologyMount Sinai HospitalUniversity of Toronto 14. Department of Maternal Fetal MedicineObstetric Ultrasound and Prenatal Diagnostic UnitKK Women' s and Children's Hospital 15. 南方医科大学南方医院妇产科产前诊断中心 16. 香港伊丽莎伯医院妇产科

一、临床标准委员会国际妇产科超声学会(ISUOG)是以推进安全的临床实践、提供高质量的医学教学、推动与妇女健康相关的影像学诊断研究为宗旨的科学组织。ISUOG临床标准委员会(CSC)的工作范畴包括制订实践指南、发布共识声明,为医疗工作... 详细信息

一、临床标准委员会国际妇产科超声学会(ISUOG)是以推进安全的临床实践、提供高质量的医学教学、推动与妇女健康相关的影像学诊断研究为宗旨的科学组织。ISUOG临床标准委员会(CSC)的工作范畴包括制订实践指南、发布共识声明,为医疗工作者提供基于业内共识的影像学诊断方法。这些指南和共识是ISUOG在其发表时确认的最优方案。虽然ISUOG会尽力确保发布内容的准确性,但学会及其雇员或会员均不会为CSC所发表的不准确或具误导性的资料、意见或陈述所造成的后果承担任何责任。ISUOG、CSC所发表的

关键词：早孕期超声检查胎儿超声头臀长双顶径妇产科