Background: Self-medication is the inappropriate use of drugs to treat self-diagnosed disorders or symptoms. Even though Self-medication has benefits as it enhances better use of clinical skills and increases access t...
详细信息
Background: Self-medication is the inappropriate use of drugs to treat self-diagnosed disorders or symptoms. Even though Self-medication has benefits as it enhances better use of clinical skills and increases access to medication;it is also associated with risks such as adverse drug reactions and antibiotics resistance. Objectives: To determine prevalence of self-medication practices among dental out-patients, triggering factors that influence self-medication practice and common source of drugs. Materials and methods: This descriptive cross-sectional study was conducted at the Clinic of the Department of Preventive Dentistry, Lagos University Teaching Hospital over a period of 6 months using self-administered questionnaires adapted from previous studies. Data obtained was analysed and expressed as frequencies and percentages. Test of associations was done using chi-square (p Results: Age of respondents ranged from 16 to 78 years (32.24 ± 13.47). M:F was 1:1. Prevalence of self-medication was 45.5%;toothache was the most prevalent reason for self-medication (71%). The frequently used drugs for self-medication were analgesics (65%) while the most common source for the drugs was the pharmacy (60%). Educational status (X2 = 12.85, P 2 = 6.42, P 2 = 10.38, P Conclusion: This study revealed high prevalence of self-medication with toothache as the predominant trigger and pharmacy, the most common source.
Hydrometallurgy is the most suitable extractive technique for the extraction and purification of manganese as compared to all other techniques including biometallurgy and pyrometallurgical processes. In the hydrometal...
详细信息
Hydrometallurgy is the most suitable extractive technique for the extraction and purification of manganese as compared to all other techniques including biometallurgy and pyrometallurgical processes. In the hydrometallurgical processing of manganese from its ore, the leach liquors often contain divalent ions such as iron, manganese, copper, nickel, cobalt and zinc along with other impurities which make manganese very difficult to separate. The processes employed for solution concentration and purification in the hydrometallurgical processing of manganese include precipitation, cementation, solvent extraction and ion exchange. Solvent extraction also proves more efficient and it plays vital roles in the purification and separation of the manganese as compared to all other techniques. A detailed review of the various steps involved in the hydrometal-lurgical manganese processing, concentration and purification processes and newer processes of extraction of manganese from ores and waste materials were discussed.
Background:The increasing occurrence of diabetes mellitus(DM)noted worldwide has considerably elicited concern in the recent *** is associated with elevated vascular complications,morbidity,mortality,and poor quality ...
详细信息
Background:The increasing occurrence of diabetes mellitus(DM)noted worldwide has considerably elicited concern in the recent *** is associated with elevated vascular complications,morbidity,mortality,and poor quality of *** this context,mesenchymal stem cells(MSCs)have shown significant therapeutic potentialities in managing and curing type 1 DM owing to their self-renewable,immunosuppressive,and differentiation *** investigated the potential action of N,N′-diphenyl-1,4-phenylenediamine(DPPD),a well-known synthetic antioxidant to enhance the therapeutic ability of the adipose-derived stem cells(AD-MSCs)in alleviating kidney and liver complications in diabetic ***:Over the four weeks of experiments,albino male rats(n=36)were split into six test groups:control,DPPD(250 mg/kg,i.p.),STZ-diabetic(D),D+DPPD,D+AD-MSCs(1×10^(6)cell/rat,i.v.),and D+AD-MSCs+DPPD treated ***:Significant declines in the renal and hepatic oxidative stress markers(MDA,ROS,and AGEs)were observed coupled with a significant elevation in many antioxidant marker levels(GSH,SOD,CAT,GPx,HO-1,and TAC)in the diabetic rats treated with either DPPD or AD-MSCs or their co-administered injection compared to the diabetic untreated *** was suggested to be the leading cause of amelioration of the kidney functions(as measured by urea,uric acid,and creatine levels)and liver functions(as evidenced by the levels of AST,ALT,ALP,bilirubin,total proteins,albumin,and globulins).Conclusion:DPPD and AD-MSCs co-administration showed superior results in terms of the enhancement of the relative hepato-renal function,indicating the beneficial role of DPPD supplementation in increasing the therapeutic potential of AD-MSCs.
暂无评论