检索结果-南通市图书馆

以田鼠作为动物模型来研究社会行为的进化:基因、脑与行为(英文)

2003年

作者： Kitchens larry j.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

动物学报 2004年第4期50卷 479-489页

作者： Miranda M. LIM Elizabeth A.D. HAMMOCK larry j. YOUNG Center for Behavioral Neuroscience Department of Psychiatry and Behavioral Sciences Emory University Atlanta GA 30322 USACenter for Behavioral Neuroscience Department of Psychiatry and Behavioral Sciences Emory University Atlanta GA 30322 USACenter for Behavioral Neuroscience Department of Psychiatry and Behavioral Sciences Emory University Atlanta GA 30322 USA

田鼠属的一些近缘种间具有独特的社会行为多态性。例如Microtusochrogaster和M .pinetorum为一夫一妻制 ,而M .montanus和M .pennsylvanicus则为独居和一夫多妻制。无论是在野外还是人工饲养的条件下 ,单配制的田鼠其雌、雄成年个体一... 详细信息

田鼠属的一些近缘种间具有独特的社会行为多态性。例如Microtusochrogaster和M .pinetorum为一夫一妻制 ,而M .montanus和M .pennsylvanicus则为独居和一夫多妻制。无论是在野外还是人工饲养的条件下 ,单配制的田鼠其雌、雄成年个体一经交配即在两者之间形成长期的配偶关系并且双亲共同哺育后代。已证明神经多肽加压素 (Vasopressin)参与了田鼠单配制行为的神经调控。本篇综述了过去以及近期关于加压素调控田鼠配偶关系形成的研究结果和进展。首先 ,阐述了加压素V1a受体 (V1aR)在脑分布的种间差异 ,并以此来鉴别特定脑区在配偶关系形成中的功能 ;其次 ,探讨了运用V1aR拮抗物的药理学方法来决定究竟哪些脑区参与配偶关系的形成 ,还描述了田鼠种间V1aR基因结构和功能的不同 ,以及这些不同对V1aR在大脑的分布和行为调控潜在的作用机制 ;最后 ,讨论了最新的研究结果 ,即对一夫多妻制田鼠进行脑V1aR基因的改造 ,从而使之表现出一夫一妻制田鼠的行为。总之。

关键词：田鼠动物模型社会行为进化基因脑

Operations management : strategy and analysis / Lee j. Kraj.wski, larry P. Ritzman. 6th ed.

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analysis of Transcriptome Changes Induced by Ptr ToxA in Wheat Provides Insights into the Mechanisms of Plant Susceptibility

2002年

作者： Lee j. Kraj.wski larry P. Ritzman.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Molecular Plant 2009年第5期2卷 1067-1083页

作者： Iovanna Pandelova Melania F. Betts Viola A. Manning larry j. Wilhelm Todd C. Mockler Lynda M. Ciuffetti Department of Botany and Plant Pathology and Center for Genome Research and Biocomputing Oregon State University Corvallis OR 97331 USA

To obtain greater insight into the molecular events underlying plant disease susceptibility, we studied transcriptome changes induced by a host-selective toxin of Pyrenophora tritici-repentis, Ptr ToxA （ToxA）, on its host plant, wheat. Transcriptional profiling of ToxA-treated leaves of a ToxA-sensitive wheat cultivar was performed using the GeneChip Wheat Genome Array. An improved and up-to-date annotation of the wheat microarray was generated and a new tool for array data analysis （BRAT） was developed, and both are available for public use via a web-based interface. Our data indicate that massive transcriptional reprogramming occurs due to ToxA treatment, including cellular responses typically associated with defense. In addition, this study supports previous results indicating that ToxA-induced cell death is triggered by impairment of the photosynthetic machinery and accumulation of reactive oxygen species. Based on results of this study, we propose that ToxA acts as both an elicitor and a virulence factor.

关键词： Gene expression transcriptome analysis defense responses fungal pathogenesis plant-microbe interactions host-selective toxin.

流式细胞术检测小鼠全血中人血小板方法的建立

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

广东医学 2010年第16期31卷 2049-2052页

作者：聂咏梅 Deborah F.Dumont larry j.Dumont 广州血液中心广州510095 Dartmouth-Hitchcock Medical Center Lebanon

目的建立一种流式细胞术检测动物模型小鼠全血中人血小板(hPLTs)的方法。方法用CO2致死SCID小鼠,立即心脏穿刺取血,用EDTA抗凝小鼠全血,备用。无菌分离5mL人的单采血小板备用。用1%多聚甲醛固定hPLTs、小鼠全血及hPLTs/小鼠全血混合血液... 详细信息

目的建立一种流式细胞术检测动物模型小鼠全血中人血小板(hPLTs)的方法。方法用CO2致死SCID小鼠,立即心脏穿刺取血,用EDTA抗凝小鼠全血,备用。无菌分离5mL人的单采血小板备用。用1%多聚甲醛固定hPLTs、小鼠全血及hPLTs/小鼠全血混合血液(V/V=1∶4),4℃过夜保存。用洗涤溶液(1%PBS+1%FBS)洗涤和重新悬浮血液,将实验分为阳性对照组、阴性对照组和实验组,用相应的样本与相应抗体反应,建立检测模板。将小鼠全血和hPLTs以1∶4比例混合,用小鼠全血以1∶10、1∶100、1∶1000、1∶10000和1∶100000按体积比稀释上述混合血液,固定,4℃过夜保存。用洗涤溶液洗涤并重新悬浮血液样本,在TruCOUNT试管中定量检测hPLTs,称为"血小板检测值"。用血细胞计数仪检测单采血小板中血小板浓度,称为"血小板期望值"。与血细胞计数仪检测到的"血小板期望值"成对比较,观察可靠的检测浓度范围。结果当血小板期望值介于3000～150000/μL时,与血小板检测值具有较好的线性关系。结论采用流式细胞仪方法,可以可靠地检测到hPLTs期望值介于3000～150000/μL浓度范围内混合在小鼠全血中的hPLTs。

关键词：流式细胞术人血小板小鼠全血抗体

Temperature Sensitivity of Nitrogen Dynamics of Agricultural Soils of the United States

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Open j.urnal of Soil Science 2020年第7期10卷 298-305页

作者： Amitava Chatterj.e Alexsandro Felipe de j.sus Diksha Goyal Sailesh Sigdel larry j. Cihacek Bhupinder S. Farmaha Sindhu j.gadamma Lakesh Sharma Daniel S. Long Department of Soil Science North Dakota State University Fargo ND USA Edisto Research and Education Center Clemson University Blackville SC USA Ecology and Evolutionary Biology The University of Tennessee Knoxville TN USA Soil and Water Sciences University of Florida Gainsville FL USA Soil and Water Conservation Research USDA-ARS Pendleton OR USA

Soil temperature controls gaseous nitrogen losses through nitrous oxide (N2O) and ammonia (NH3) fluxes. Eight surface soils from agricultural fields across the United States were incubated at 10°C, 20°C, and 30°C, and N2O and NH3 flux were measured twice a week for 91 and 47 d, respectively. Changes in cumulative N2O and NH3 flux and net N mineralization at three temperatures were fitted to calculate Q10 using the Arrhenius equation. For the maj.rity of soils, Q10 values for the N2O loss ranged between 0.23 and 2.14, except for Blackville, North Carolina (11.4) and j.ckson, Tennessee (10.1). For NH3 flux, Q10 values ranged from 0.63 (Frenchville, Maine) to 1.24 (North Bend, Nebraska). Net soil N mineralization-Q10 ranged from 0.96 to 1.00. Distribution of soil organic carbon and total soil N can explain the variability of Q10 for N2O loss. Understanding the Q10 variability of soil N dynamics will help us to predict the N loss.

关键词： Arrhenius Equation Soil Organic Carbon Inorganic Nitrogen Gaseous Losses of Nitrogen

International Union for Biological Sciences Symposium on Integrative Biology of Reproductive and Social Behaviors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrative Zoology 2007年第1期2卷 36-55页

作者： larry j.YOUNG 不详

SRA regulates female meiosis,ovulation and reproductive behavior in Drosophila Toshiro AIGAKI Department of Biology,Tokyo Metropolitan University,Minamiosawa,Tokyo,j.pan(aigaki-toshiro@***)Mating induces dramatic changes in the reproductive behavior of females in Drosophila *** better understand the genetic bases of post-mating responses in females,we screened a collection of P{GS}insertion lines,and identified sarah(sra),whose misexpression in the nervous system induced high levels of ovulation in *** flies also extruded the ovipositor toward courting males as seen in wild-type mated females,supporting the notion that ovulation and behavioral patterns are physiologically *** sra insertions were found to be hypomorphic alleles with reduced expression levels.

关键词： insertion bases behavior

A new strategy for ionospheric remote sensing using the 130.4/135.6 nm airglow intensity ratios

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earth and Planetary Physics 2023年第4期7卷 445-459页

作者： XiaoHan Yin j.anQi Qin larry j.Paxton School of Earth and Space Sciences Peking UniversityBeijing 100871China Applied Physics Laboratory Johns Hopkins UniversityLaurelMD 20723USA

We demonstrate here that global-scale determination of a key ionospheric parameter,the peak height of the F_(2)region(h_(m)F_(2)),can be obtained by making a simple ratio measurement of the atomic oxygen 130.4 and 135.6 nm emissions in the far-ultraviolet nightglow with a nadir-viewing system such as a pair of photometers suitable for flight on a *** further demonstrate that measurements from an altitude that is within the typical range of nighttime h_(m)F_(2)250−450 km can provide the ratios that are needed for retrieval of the h_(m)F_(2).Our study is conducted mostly through numerical simulations by using radiative transfer models of the two emissions coupled with empirical models of the atmosphere and *** results show that the relationship between the h_(m)F_(2)and the intensity ratio is sensitive to the altitude from which the emissions are observed,primarily because of the distinctly different degrees of resonant scattering of the two emissions in the atmosphere.A roughly quadratic relationship can be established for observations from an orbit of~400 km,which enables h_(m)F_(2)*** analysis indicates that the relationship can be affected by the ambient atmospheric conditions through resonant scattering and O2 *** typical nighttime conditions with h_(m)F_(2)250−450 km,retrieval of the h_(m)F_(2)from synthetic observations shows that the typical errors are only a few kilometers(up to~20 km),depending on the accuracy of the ambient conditions predicted by the empirical *** findings pave the way for use of the 130.4/135.6 nm intensity ratios for global-scale monitoring of the nighttime ionosphere at mid to low latitudes.

关键词： nighttime ionosphere far-ultraviolet remote sensing 130.4/135.6 nm airglow intensity ratio peak height of the F_(2)region(h_(m)F_(2)) TIMED observation

Evolutionary diversity as a catalyst for biological discovery

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2018年第6期13卷 616-633页

作者： Zachary V.j.HNSON larry j.YOUNG School of Biological Sciences Georgia Institute of TechnologyAtlantaGeorgiaUSA Center for Translational Social Neuroscience Silvio O.Conte Center for Oxytocin and Social CognitionDepartment of Psychiatry and Behavioral SciencesYerkes National Primate Research CenterEmory UniversityAtlantaGeorgiaUSA

The tremendous diversity of animal behaviors has inspired generations of scientists from an array of biological *** complement investigations of ecological and evolutionary factors contributing to behavioral evolution,modern sequencing,gene editing,computational and neuroscience tools now provide a means to discover the proximate mechanisms upon which natural selection acts to generate behavioral *** behaviors are motivated behaviors that can differ tremendously between closely related species,suggesting phylogenetic plasticity in their underlying biological *** addition,convergent evolution has repeatedly given rise to similar forms of social behavior and mating systems in distantly related *** behavioral divergence and convergence provides an entry point for understanding the neurogenetic mechanisms contributing to behavioral *** argue that the greatest strides in discovering mechanisms contributing to social behavioral diversity will be achieved through integration of interdisciplinary comparative approaches with modern tools in diverse species *** review recent advances and future potential for discovering mechanisms underlying social behavioral variation;highlighting patterns of social behavioral evolution,oxytocin and vasopressin neuropeptide systems,genetic/transcriptional“toolkits,”modern experimental tools,and alternative species systems,with particular emphasis on Microtine rodents and Lake Malawi cichlid fishes.

关键词： cichlids oxytocin and vasopressin social behavior toolkits voles

The varicocele： diagnostic dilemmas, therapeutic challenges and future perspectives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian j.urnal of Andrology 2016年第2期18卷 276-281,J0007页

作者： Koj. Chiba Ranj.th Ramasamy Dolores j.Lamb larry I Lipshultz Center for Reproductive Medicine Baylor College of Medicine Houston TX USA Scott Department of Urology Baylor College of Medicine Houston TX USA Department of Molecular and Cellular Biology Baylor College of Medicine Houston TX USA.

A varicocele is defined as the abnormal dilation of the internal testicular vein and pampiniform venus plexus within the spermatic cord. If a semen analysis is not obtained from the adolescent male, in the absence of other symptoms, the main clinical indication used by many urologists to recommend repair is testicular atrophy. The varicocele may result in testicular damage in some males causing testicular atrophy with impaired sperm production and decreased Leydig cell function, while in other males the varicocele may seemingly cause no ill effects. In adult men, varicoceles are frequently present and surgically correctable, yet the measurable benefits of surgical repair are slight according to a Cochrane review. While occurring more commonly in infertile men than fertile men, only 20% of men with a documented varicocele will suffer from fertility problems. Most varicoceles found in adolescents are detected during a routine medical examination, and it is difficult to predict which adolescent presenting with a varicocele will ultimately show diminished testicular function in adolescence or adulthood. As in adults, the mainstay of treatment for varicocele in adolescents is surgical correction. However, unlike an adult varicocelectomy （the microsurgical approach is the most common）, treatment for an adolescent varicocele is more often laparoscopic. Nevertheless, the goals of treatment are the same in the adolescent and adult patients. Controversy remains as to which patients to treat, when to initiate the treatment, and what type of treatment is the best. This review will present the current understanding of the etiology, diagnosis and treatment of the adolescent varicocele.

关键词： adolescent adult management varicocele