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Left intracardiac thrombosis: An exceptional complication revealing BehCet’s disease

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Open Journal of Internal Medicine 2013年第1期3卷 15-18页

作者： Mounira El Euch Ben Fredj Ismail Fatma Rezgui Amel Karmani Monia Derbali Fatma Amri Raja laouani kechrid chedia Department of Internal Medicine Sahloul University Hospital Sousa Tunisia

Although cardiac involvement during Behcet syndrome is uncommon and intracardiac thrombosis is exceptional, it concerns the right ventricle much more than the left one. We report an illustrative case of left intracard... 详细信息

关键词： Behcet’s Disease Cardiac Involvement Thrombosis

Sea-blue histiocytes syndrome: Case report and review of literature

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Open Journal of Internal Medicine 2013年第1期3卷 19-21页

作者： Mounira El Euch Fatma Ben Fredj Ismail Amel Rezgui Monia Karmani Belgacen Mrad Hassen Hosi Mhiri chedia laouani kechrid Department of Internal Medicine Sahloul Hospital Soussa Tunisia

A 57-year-old female was admitted with pancytopenia, and mild splenomegaly. The multiple myeloma diagnosis was wrongly made since the discovery of monoclonal peak to the protein electrophoresis. Further microscopic examination of bone marrow revealed the accumulation of sea-blue histiocytes. The evolution was stable and the patient did not receive any treatment due to the lack of nervous symptoms.

关键词： Syndrome of the Sea-Blue Histiocyte Pancytopenia Splenomegaly

Vogt-Koyanagi-Harada syndrome associated to hypothyroidism revealed by myocarditis

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Open Journal of Internal Medicine 2012年第3期2卷 176-178页

作者： F.Ben Fredj Ismail A.Mzabi M.Karmani A.Rezgui H.Mhiri C.laouani-kechrid Department of Internal Medicine Sahloul HospitalSousseTunisia

Purpose: Vogt-Koyanagi-Harada (VKH) syndrome is usually defined as an uveo-meningitis who may be associated with auditory and cutaneous signs. Association of VKH syndrome and autoimmune thyroiditis is uncommon. Observation: A 28-year-old man was admitted with thoracic pain due to myocarditis. Two years ago he presented VKH syndrome with specific ocular manifestation and deafness, treated by corticosteroids and immunosuppressive. Etiologic investigation of myocarditis concluded to deep hypothyroidism related to Hashimoto thyroiditis. The patient improved after substitutive treatment by thyroid hormones. Conclusion: Thyroid function should be systematically investigated in case of VKH syndrome and particularly when associated to dysthyroidism symptoms.

关键词： Vogt-Koyanagi-Harada Myocarditis Hypothyroidism Hashimoto Thyroiditis

Non-secretory multiple myeloma with lytic bone lesions about a new observation

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Open Journal of Internal Medicine 2012年第3期2卷 179-182页

作者： M. El Euch F. Ben Fredj Ismail A. Rezgui M. Karmani F. Derbali R. Amri C. laouani-kechrid Department of Internal Medicine Sahloul Hospital Sousse Tunisia

Non-secretory myeloma is a rare variety of multiple myeloma. Classical techniques of chronic secretion’s research don’t find any immunoglobulin monoclonal peak in the patient’s blood. Lytic bone lesions are rare in this type of myeloma. We report the case of a patient in whom we confirmed multiple myeloma by bone marrow aspiration and we have classified stage III of Durie and Salmon in view of hypercalcemia, anemia, and lytic lesions observed. However, we could not isolate a secretion of monoclonal immunoglobulin in blood but urinary secretion was evident by proteinuria and urinary light chains. The radiographs of our patient found diffuse osteolysis and practice of sternal puncture confirmed multiple myeloma. Our case is original because of rarity on non secretory myeloma particularly with diffuse osteolytic lesion.

关键词： Non-Secretory Myeloma Immunoglobulin Hypercalcemia Anemia Lytic Bone Lesions