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羊毛甾醇合酶基因多态性和内源性哇巴因变化对低钠盐摄入的反应

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中华高血压杂志 2016年第1期24卷 25-25页

作者：刘莉叶鹏 lanzani c Gatti G citterio L Messaggio E Delli carpini S Simonini M casamassima N Zagato L Brioni E Hamlyn JM Manunta P

钠缺乏时,循环中内源性哇巴因（endogenous ouabain,EO;一种肾上腺皮质来源的血管加压素）水平增加。此外,羊毛甾醇合酶（一种参与胆固醇生物合成的酶）的一种错义基因多态性突变（rs2254524V642L）可影响肾上腺皮质细胞的EO生物合成。

关键词：羊毛甾醇合酶哇巴因肾上腺皮质细胞轻度高血压血管加压素钠盐摄入生物合成 endogenous 基因多态性

The role of an integration identity in the analysis of the cauchy-Leray transform

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Science china Mathematics 2017年第11期60卷 1923-1936页

作者： lanzani Loredana STEIN Elias M. Department of Mathematics Syracuse University Department of Mathematics Princeton University

The purpose of this paper is to complement the results by lanzani and Stein(2017) by showing the dense definability of the cauchy-Leray transform for the domains that give the counter-examples of lanzani and Stein(2017), where L^p-boundedness is shown to fail when either the "near" c^2 boundary regularity, or the strong c-linear convexity assumption is dropped.

关键词： Hardy space cauchy integral cauchy-Szego projection Lebesgue space pseudoconvex domain minimal smoothness Leray-Levi measure

The role of an integration identity in the analysis of the cauchy-Leraytransform

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中国科学：数学 2017年第11期47卷 J0001-J0006页

作者： lanzani Loredana STEIN Elias M. Department of Mathematics Syracuse University Department of Mathematics Princeton University

The purpose of this paper is to complement the results by lanzani and Stein （2017） by showing thedense definability of the cauchy-Leray transform for the domains that give the counter-examples of lanzani andStein （2017）, where LP-boundedness is shown to fail when either the ＂near＂ c2 boundary regularity, or the strongc-linear convexity assumption is dropped.

关键词： Hardy space cauchy integral cauchy-Szego projection Lebesgue space pseudoconvex do-main minimal smoothness Leray-Levi measure

cO Dissociation and cO+O Reactions on a Nanosized Iron cluster

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Nano Research 2009年第8期2卷 660-670页

作者： Giorgio lanzani Albert G.Nasibulin Kari Laasonen Esko I.Kauppinen Department of chemistry P.O.Box 3000FIN-90014 University of OuluFinland Department of Applied Physics and center for New Materials Helsinki University of TechnologyP.O.Box 5100FIN-02150 EspooFinland

catalysis over metal nanoparticles is essential for the growth of carbon nanotubes and all the properties of the resulting nanotube,such as diameter and chirality,are affected by the metal ***,it is very important to understand the carbon chemistry taking place on nanometer size metal *** we present the fi rst ab initio computational study of chemical reactions on a nanosized iron *** clusters have reaction sites,such as edges and vertexes between the facets,Which have not been studied *** principles electronic structure calculations,fully incorporating the effects of spin polarization and non-collinear magnetic moments,have been used to investigate cO disproportionation on an isolated Fe55 *** cO dissociation,O atoms remain on the surface while c atoms move into the cluster,presumably as the initial step toward carbide *** we show that the lowest cO dissociation barrier found on the cluster(0.77 eV)is lower than on most previously studied Fe *** dissociation occurs on a vertex between the *** possible paths for cO2 formation were identifi *** calculated lowest reaction barrier is 1.08 eV,which is comparable to the barrier of 0.65 eV obtained by experiment.

关键词： Nanoparticle density functional theory(DFT) mechanism synthesis

全基因组和基于基因的荟萃分析识别影响氢氯噻嗪血压反应的新型基因位点

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中华高血压杂志 2016年第11期24卷 1007-1007页

作者：刘莉叶鹏 Salvi E Wang Z Rizzi F Gong Y McDonough cW Padmanabhan S Hiltunen TP lanzani c Zaninello R chittani M Bailey KR Sarin AP Barcella M Melander O chapman AB Manunta P Kontula KK Glorioso N cusi D Dominiczak AF Johnson JA Barlassina c Boerwinkle E cooper-DeHoff RM Turner ST

本研究旨在识别影响氢氯噻嗪单药治疗降压反应的新基因位点。纳入来自国际抗高血压药物基因组学研究联合会的6个临床试验中的白人高血压患者1739例,进行氢氯噻嗪降压反应的全基因组荟萃分析。此外,研究者对先前有证据表明其参与利尿反... 详细信息

本研究旨在识别影响氢氯噻嗪单药治疗降压反应的新基因位点。纳入来自国际抗高血压药物基因组学研究联合会的6个临床试验中的白人高血压患者1739例,进行氢氯噻嗪降压反应的全基因组荟萃分析。此外,研究者对先前有证据表明其参与利尿反应、血压调节或高血压易感性的候选基因进行了基于基因的分析。

关键词：血压调节基因位点荟萃分析抗高血压药物基因组研究抗高血压治疗缝隙连接蛋白叉头 junction 候选基因