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Factors associated with healthy ageing:a comparative study between China and the United States

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China Population and Development Studies 2021年第1期4卷 262-283页

作者： lanlan chu Lu Chen Department of Economics and Political Science St.Catherine UniversitySt.PaulMNUSA Research Center of Healthy Aging and Social Security Nankai UniversityNo.38 Tongyan RoadJinnan DistrictTianjin 300350People’s Republic of China School of Finance Nankai UniversityNo.38 Tongyan RoadJinnan DistrictTianjin 300350People’s Republic of China

This study compares the associators of healthy ageing in China and the United States,using the 2005-2014 Chinese Longitudinal Healthy Longevity Survey(CLHLS)and the 2004-2014 Health and Retirement Study(HRS).Health ageing is measured using an overall healthy ageing index(HAI),defined according to five dimensions:no major chronic diseases,free of physical functional impairment,free of cognitive impairment,no depressive symptoms,and socially active *** logistic regression analysis is adopted to explore the association of demographic characteristics,socioeconomic status,and healthy lifestyles with the odds ratios of healthy ageing in China and the United *** indicate that the proportion of individuals experiencing healthy ageing is slightly higher in US than Chinese older adults aged 65-100(25.67%vs 23.27%).Nevertheless,Chinese oldest-old(80-100)have a higher proportion of healthy ageing than American oldest-old(15.05%vs.12.19%).Our results indicate that the odds of healthy ageing decrease with age,whereas they increase with education,income,marriage,and health *** odds of healthy ageing are lower for older Chinese women than men,whereas the odds are higher for older US ***,non-white elders in the United States have significantly lower odds of healthy ageing than their white *** findings suggest certain similar patterns of healthy ageing across two countries,but distinct patterns do *** gender and racial equalities in healthy ageing are crucial for Chinese and American policymakers,respectively.

关键词： Healthy ageing China United States Health policy

Does informal care impact the use of healthcare services in China?Evidence from the perspective of drug utilization

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China Population and Development Studies 2023年第3期7卷 239-256页

作者： Lu Chen Hongli Fan lanlan chu School of Finance Nankai UniversityNo.38 Tongyan RoadJinnan DistrictTianjin 300350People’s Republic of China School of Insurance Shandong University of Finance and EconomicsNo 40 Shungeng RoadShizhong DistrictJinan 250000People’s Republic of China Economics and Political Science Department St.Catherine UniversitySt.PaulMNUSA

Based on the 2011-2018 China Health and Retirement Longitudinal Study(CHARLS),we investigated the effect of informal care on caregivers’utilization of medical drugs using the instrumental variable method with fixed *** results indicate that caregivers are more likely to take medical drugs than ***,caregivers tend to take a significantly higher number of drugs than non-caregivers,particularly those treating physical ***,the effect of informal care on the drug utilization is found more significant among those aged 45-54,male caregivers,and those who provide care for their parents-in-law compared to their respective *** further identified channels through which informal care contributes to caregivers’higher drug *** channels include an increased risk of developing chronic diseases,a higher number of chronic diseases,lower their self-reported health,and reduced social *** results offer implications for policymakers in overcoming the challenges of establishing and developing a supportive system for informal care in China.

关键词： Caregivers Aging Social activities Self-reported health Fixed effects

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家庭老年照料对女性劳动就业的影响研究

经济研究 2016年第3期51卷 176-189页

作者：陈璐范红丽赵娜褚兰兰南开大学金融学院邮政编码300350 南开大学经济学院德州理工大学经济系

本文基于1991—2011年"中国健康与营养调查"数据,采用面板数据和工具变量方法,实证检验了为父母公婆提供家庭照料对女性劳动就业的影响。研究发现,照料活动与女性的劳动参与率和提前退休决策之间存在内生关系;每周提供20小时以上高强度... 详细信息

本文基于1991—2011年"中国健康与营养调查"数据,采用面板数据和工具变量方法,实证检验了为父母公婆提供家庭照料对女性劳动就业的影响。研究发现,照料活动与女性的劳动参与率和提前退休决策之间存在内生关系;每周提供20小时以上高强度照料会使女性难以兼顾照料和工作,产生"门槛效应",劳动参与率显著下降7.31%;对于仍然劳动的女性,照料责任会使其每周减少劳动时间2.8—4.8小时;每月劳动收入减少7.21%;对于45—49岁的城镇女性,家庭老年照料并没有显著提升其提前退休的概率。此外,照料责任对劳动力市场供给的影响在居住安排和劳动力自身竞争力方面存在异质性。据此本文推断,家庭老年照料对于女性劳动力供给产生抑制作用。这些经验发现为今后我国制定家庭照料者支持政策及劳动就业政策提供了依据。

关键词：家庭老年照料劳动参与率劳动收入

长江口及其邻近海域表层沉积物中有机污染物复合毒性与多环芳烃毒性贡献

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生态毒理学报 2022年第1期17卷 213-223页

作者：楚兰兰解满俊王茜李娟英上海海洋大学海洋生态与环境学院上海201306 上海海滨污水处理有限公司上海201302

本研究利用发光细菌急性毒性实验测定了长江口及其邻近海域表层沉积物中有机污染物的复合毒性,同时运用气相色谱-质谱联用仪测定了沉积物中16种美国环境保护局(United States Environmental Protection Agency,US EPA)规定的优先控制的... 详细信息

本研究利用发光细菌急性毒性实验测定了长江口及其邻近海域表层沉积物中有机污染物的复合毒性,同时运用气相色谱-质谱联用仪测定了沉积物中16种美国环境保护局(United States Environmental Protection Agency,US EPA)规定的优先控制的多环芳烃(polycyclic aromatic hydrocarbons,PAHs)的浓度。在此基础上,分析其时空分布特征及多环芳烃毒性贡献,并评估其环境风险。结果表明,2019年长江口及邻近海域表层沉积物中16种PAHs总浓度范围为32.84~283.47 ng·g^(-1);2020年浓度范围为66.93~132.64 ng·g^(-1)。在空间分布上,2019年长江口表层沉积物中PAHs在靠近渔港的区域呈现较高浓度(S3=(283.47±29.94)ng·g^(-1)),而2020年在靠近舟山岛的区域呈现较高浓度(L6=(132.64±9.95)ng·g^(-1))。与2019年相比,2020年多环芳烃的平均浓度有所降低,且其细胞毒性量化指标——生物分析当量浓度(BEQ_(bio))的平均值(66.62 mg·kg^(-1))远低于2019年(128.20 mg·kg^(-1))。在长江口沉积物毒性当量浓度中PAHs所占比例较小,2019年和2020年由PAHs引起的细胞毒性的平均占比分别为4.46%和4.25%。该结果表明,检测到的PAHs仅能解释所观察到的复合毒性效应的一小部分,因此,还需要进一步对其他未检测的化学物质进行测试分析。

关键词：多环芳烃沉积物复合毒性毒性贡献长江口

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超声预处理对锂辉石矿物浮选分离的影响

中国有色金属学报 2024年第2期34卷 586-597页

作者：张宇新陈兰兰褚浩然卢东方王毓华中南大学资源加工与生物工程学院长沙410083

采用NaOH溶蚀与超声波耦合机械搅拌相结合的预处理技术对锂辉石、石英和长石进行浮选前预处理,以探究超声预处理对锂辉石矿物浮选分离的影响。通过开展单矿物浮选和人工混合矿浮选试验,比较超声波耦合机械搅拌与传统机械搅拌两种预处理... 详细信息

采用NaOH溶蚀与超声波耦合机械搅拌相结合的预处理技术对锂辉石、石英和长石进行浮选前预处理,以探究超声预处理对锂辉石矿物浮选分离的影响。通过开展单矿物浮选和人工混合矿浮选试验,比较超声波耦合机械搅拌与传统机械搅拌两种预处理技术的优缺点;为了探明预处理技术的作用机理,对经不同预处理后的矿样进行了SEM、吸附量测试和XPS分析。结果表明:超声预处理后,锂辉石与长石、石英之间的可浮性差异进一步增大,-0.074+0.038 mm粒级的锂辉石人工混合矿精矿浮选回收率最高可达48.23%,分选效率达到44.27%;相较于传统机械搅拌预处理,超声波耦合机械搅拌预处理的浮选效果进一步提高。介入超声波预处理后可进一步改变锂辉石矿物表面形貌,并促进更大范围的表面溶蚀,从而增加矿物表面药剂吸附,且超声波耦合机械搅拌预处理后的锂辉石比传统机械搅拌预处理后的锂辉石具有更强的NaOL吸附能力,可见超声预处理技术对锂辉石、石英和长石的浮选分离具有显著的促进作用。

关键词：锂辉石浮选超声波预处理选择性溶蚀

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住院患者营养状况评估分析

黑龙江科学 2022年第14期13卷 98-99,141页

作者：储兰兰潘世芹龚意滁州市第一人民医院营养科安徽滁州239000

为评估住院患者营养状况,分析其在不同系统疾病、年龄、性别中的分布特点,选取了202例新住院患者,采用营养风险筛查2002(NRS2002)量表评估其营养风险,并测定营养相关指标。结果表明,营养风险发生率在各系统疾病组间差异显著(P=0.002),... 详细信息

为评估住院患者营养状况,分析其在不同系统疾病、年龄、性别中的分布特点,选取了202例新住院患者,采用营养风险筛查2002(NRS2002)量表评估其营养风险,并测定营养相关指标。结果表明,营养风险发生率在各系统疾病组间差异显著(P=0.002),且老年组显著高于中青年组(P=0.001);营养缺乏型患者老年组高于中青年组(P=0.049);低蛋白血症在各系统疾病组间(P=0.034)及血清总蛋白水平在各系统疾病(P=0.022)和不同年龄(P=0.038)中的差异均具有统计学意义。这些说明住院患者营养不良问题普遍存在,分布特点因系统疾病、年龄不同而不同。

关键词：住院患者营养风险营养状况

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Ultrasound application in alkaline pretreatment process of spodumene to improve particle floatability

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International Journal of Mining Science and Technology 2023年第7期33卷 883-891页

作者： Haoran chu lanlan Chen Dongfang Lu Yuhua Wang Xiayu Zheng Guangli Zhu School of Minerals Processing and Bioengineering Central South UniversityChangsha 410000China Zhongyuan Critical Metals Laboratory Zhengzhou UniversityZhengzhou 450001China

Selective surface dissolution was found to be important in spodumene flotation. In this study, we proposed to introduce ultrasound into the pretreatment process to accelerate particle vibration and cavitation, as well as the migration of mineral surface components to solution. Micro-flotation results showed that the flotation recovery of spodumene can be 86.08% by ultrasound pretreatment, but only 39.30% by traditional mechanical agitation pretreatment. Compared with traditional mechanical agitation, ultrasonic pretreatment can shorten the pretreatment process, reduce the dosage of agents, reduce the mechanical agitation speed, and improve the efficiency of the pretreating process. Inductively coupled plasma analysis showed that, in the ultrasonic system, the amount of Li, Al, and Si species in the solution was twice as much as those in the traditional preprocessing system. Moreover, the scanning electron microscope results demonstrated a larger surface dissolution area in the ultrasonic system. X-Ray photoelectron spectroscopy results showed that the atomic concentration of Si species on the spodumene surface decreased, whereas the relative atomic concentrations of Li and Al species increased, indicating that the ultrasound effect strengthened the selective dissolution of elements on the mineral *** high-resolution spectra of O 1s showed that more collectors are adsorbed on the mineral surface treated by ultrasonic pretreatment.

关键词： Ultrasonic pretreatment Spodumene Flotation Surface selective dissolution

β-细辛醚通过抑制TRPV4的表达缓解谷氨酸诱导的Ca^(2+)超载

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合肥工业大学学报（自然科学版） 2024年第2期47卷 263-269页

作者：蒋兰兰陈向涛储涛蔡静雯刘浩宇尹兰香安徽医科大学药学院安徽合肥230022 中国科学技术大学附属第一医院(安徽省立医院)药剂科安徽合肥230001

谷氨酸处理会导致Ca^(2+)超载,瞬时受体电位香草素受体4(transient receptor potential vanilloid 4,TRPV4)在其中的作用及可能机制尚不清楚。β-细辛醚能快速透过血脑屏障,对兴奋性毒性具有较强的神经保护作用。文章以高分化的PC12细... 详细信息

谷氨酸处理会导致Ca^(2+)超载,瞬时受体电位香草素受体4(transient receptor potential vanilloid 4,TRPV4)在其中的作用及可能机制尚不清楚。β-细辛醚能快速透过血脑屏障,对兴奋性毒性具有较强的神经保护作用。文章以高分化的PC12细胞为研究对象,探究β-细辛醚(15、30、60μmol/L)预处理4 h,40 mmol/L谷氨酸处理实时记录对PC12细胞Ca^(2+)浓度的影响,采用钙成像技术检测Ca^(2+)浓度的变化;采用实时荧光定量聚合酶链式反应(polymerase chain reaction,PCR)、Western Blot及免疫荧光技术检测TRPV4的mRNA和蛋白的表达;采用Lipofectiamine 2000脂质体实验转染TRPV4-siRNA和pEX-3-TRPV4,观察沉默和过表达TRPV4对谷氨酸引起Ca^(2+)超载的影响。结果表明:与正常对照组相比,谷氨酸处理5 min可诱导Ca^(2+)超载,显著提高TRPV4的mRNA和蛋白的表达;与模型组相比,β-细辛醚能够剂量依赖性地降低谷氨酸诱导的Ca^(2+)超载和TRPV4的表达;沉默TRPV4抑制细胞Ca^(2+)超载;过表达TRPV4则部分逆转β-细辛醚抑制谷氨酸诱导的Ca^(2+)超载。该研究证明,谷氨酸处理PC12细胞5 min通过上调TRPV4的表达诱导Ca^(2+)超载,β-细辛醚作为TRPV4的拮抗剂,是一种潜在的抑制兴奋性毒性的药物。

关键词：谷氨酸兴奋性毒性 β-细辛醚瞬时受体电位香草素受体4(TRPV4) Ca^(2+)超载

Inhibitory effect of resveratrol on the proliferation of GH3 pituitary-adenoma cells and voltage-dependent potassium current

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Neural Regeneration Research 2006年第6期1卷 481-484页

作者： Ming chu lanlan Wei Chao Wang Yu Cheng Kongbin Yang Baofeng Yang Department of Neurosurgery First Clinical Hospital Harbin Medical University Harbin 150001 Heilongjiang Province China Department of Microbiology Harbin Medical University Harbin 150001 Heilongjiang Province China Department of Pharmacology Harbin Medical University Harbin 150001 Heilongjiang Province Chnia

BACKGROUND ： Recent researches indicate that activation of potassium channel is likely to cause many kinds of cells to proliferate and differentiate; using chemical to block the potassium channel can restrain the proliferation of small lung-cancer cells, breast cancer, prostate cancer and human lymphocyte, etc. Previous researches proved that resveratrol （RE）, a selective estrogen receptor modulator （SERM）, could inhibit growth of GH3 cells, induce apoptosis, and resist tumor through interfering K^＋ channel. OBJECTIVE ： To investigate the effects of RE on voltage-dependent K^＋ current GH3 pituitary-tumor cells, DESIGN： Observational contrast study SETTING ： Department of Neurosurgery, the First Clinical Hospital of Harbin Medical University; Department of Microbiology, Harbin Medical University; Department of Pharmacology, Harbin Medical University. MATERIALS： GH3 pituitary-tumor cell line of rats was purchased from the American Type Culture Collection （ATCC）. RE and [3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyl-tetrazolium bromide] （MTT） were obtained from Sigma Chemical Co, St Louis, USA; Ham＇s F-10 medium from Gibco BRL; Equine serum and fetal bovine serum from Hyclone Laboratones, Logan, UT; FACSCalibur flow cytometer from BD Company, USA, RE was dissolved in ethanol and stored at -20 ℃, It was diluted to different concentrations （10, 50, 100 μmol/L） with medium and extra cellular solution when needed, The final concentration of ethanol was less than 0.01%.METHODS： The experiment was carded out in the Department of Microbiology and Pharmacology of Harbin Medical University from March 2005 to January 2006, （1） Cell preparation： Proliferating indexes affected by 10, 50 and 100 μmol/L RE were measured with MTT, respectively. 0.000 1 volume fraction of ethanol was added into control group. Inhibitory rate of cellular growth was calculated as the following formula： Inhibitory rate （%） = （1 - A value in experimental group/A value in control group）×100%, The exp

关键词： flow cytometry cell cycle cell proliferation potassium channel volume fraction analysis of variance growth suppression Culture Collection potassium current estrogen receptor flow cytometer patch clamp cell line