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Journal of Traditional Chinese Medicine 2025年第1期45卷 176-183页

作者： lang Jiawang JIN Lingqing LUO Jianchang lang Boxu Department of Acupuncture and Massage Municipal Hospital Affiliated to Medical School of Taizhou University

OBJECTIVE: To explore the efficacy and safety of acupuncture combined with atlantoaxial joint bone-setting therapy for the treatment of Tourette syndrome. METHODS: We randomly divided 600 patients at a ratio of 1∶1∶1 into three groups: group A(acupuncture combined with atlantoaxial joint bone setting therapy group), group B(acupuncture group), and group C(tiapride group). After two months of treatment, the Yale global tic severity scale(YGTSS) score reduction, improvement in social function impairment, clinical efficacy, and long-term efficacy in the three groups were compared. RESULTS: After treatment, in the analysis of YGTSS score reduction, social function impairment improvement, the clinical control rate, and long-term efficacy, the results were all Group A > Group B > Group C, with a statistically significant difference(P < 0.05). However, the total clinical efficacy of treatment in group A(94.9%) was not significantly different from that in group B(91.8%). Adverse reactions did not occur in groups A and B, and several adverse reactions occurred in 29%(n = 58) of the group C patients. CONCLUSION: Compared with traditional drug therapy, acupuncture combined with atlantoaxial joint bone setting therapy has better clinical and long-term efficacy. This treatment strategy can improve the social function of children and prevent adverse reactions to drugs.

关键词： Tourette syndrome acupuncture atlanto-axial joint bone setting randomized controlled trial tiapride hydrochloride

Multiplicative forms on Poisson groupoids

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Science China Mathematics 2025年第1期68卷 169-206页

作者： Zhuo Chen Honglei lang Zhangju Liu Department of Mathematical Sciences Tsinghua UniversityBeijing 100084China College of Science China Agricultural UniversityBeijing 100083China School of Mathematics and Statistics Henan UniversityKaifeng 475004China

First,we prove a decomposition formula for any multiplicative differential form on a Lie groupoid ***,we prove that if G is a Poisson Lie groupoid,then the spaceΩ_(mult)·(G)of multiplicative forms on G has a differential graded Lie algebra(DGLA)***,when combined withΩ·(M),which is the space of forms on the base manifold M of G,Ω_(mult)·(G)forms a canonical DGLA crossed *** supplements a previously known fact that multiplicative multi-vector fields on G form a DGLA crossed module with the Schouten algebraΓ(∧·A)stemming from the Lie algebroid A of G.

关键词： multiplicative form Poisson groupoid Lie algebra crossed module characteristic pair

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Temperature-sensitive Micelles as Artificial Chaperones for Insulin Protection

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Chinese Journal of Polymer Science 2025年第2期43卷 350-359页

作者： Jia-Wen Chen Yan Xiao Mei-Dong lang Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of EducationSchool of Materials Science and EngineeringEast China University of Science and TechnologyShanghai200237China

Insulin is an essential and versatile protein taking part in the control of blood glucose levels and protein ***,under prolonged storage or high temperature stress,insulin tends to unfold and aggregate into toxic amyloid fibrils,leading to loss of physiological *** by natural chaperones,a series of temperature-sensitive polycaprolactone-based micelles were designed to prevent insulin from *** micelles were fabricated through the self-assembly of amphiphilic copolymers of methoxy poly(ethylene glycol)-poly(4-diethylformamide caprolactone-co-caprolactone)(mPEG_(17)-P(DECL-co-CL)),which had a regular spherical morphology with particle sizes of about 100 *** addition,the lower critical solution temperature(LCST)of the micelles could be tuned to 9 and 29℃by changing the ratio of DECL to *** from the temperature-sensitivity of DECL segment,the binding ability of micelles to insulin could be modulated by changing the *** LCST,micelles effectively inhibited insulin aggregation and protected it from thermal inactivation due to the strong binding ability between the hydrophobic segment DECL and *** LCST,DECL segment returned to hydrophilic and bound weakly with insulin,leading to the release of insulin and assisting in its recovery of secondary ***,these temperature-sensitive micelles provided an effective strategy for insulin protection.

关键词： Temperature-sensitive Insulin Micelles Chaperones

Synergistic enhancement of ion/electron transport by ultrafine nanoparticles and graphene in Li2FeTiO4/C/G nanofibers for symmetric Li-ion batteries

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Journal of Energy Chemistry 2025年第02期101卷 42-51页

作者： Wenjie Ma Yakun Tang Yue Zhang Xiaohui Li lang Liu Xueting Wang Yuliang Cao State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources Key Laboratory of Energy Materials Chemistry Ministry of Education College of Chemistry Xinjiang University College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University

Low-cost Fe-based disordered rock salt（DRX） Li2FeTiO4is capable of providing high capacity(295 mA h g-1) by redox activity of cations(Fe2+/Fe4+and Ti3+/Ti4+) and anionic ***,DRX structures lack transport channels for ions and electrons,resulting in sluggish kinetics,poor electrochemical activity,and ***,graphene conductive carbon network permeated Li2FeTiO4（LFT/C/G） nanofibers are successfully prepared by a facile sol-gel assisted electrospinning *** Li2FeTiO4nanoparticles（2 nm） and one-dimensional（1D） structure provide abu ndant active sites and unobstructed diffu sion channels,accelerating ion *** addition,introducing graphene reduces the band gap and Li+diffusion barrier and improves the dynamic properties of Li2FeTiO4,thus achieving a relatively mild interfacial reaction and reversible redox *** expected,the LFT/C/1.0G cathode delivers a remarkable discharge capacity(238.5 mA h g-1),high energy density(508.8 Wh kg-1),and excellent rate capability(51.2 mA hg-1at 1.0 A g-1).Besides,the LFT/C/1.0G anode also displays a high capacity(514.5 mA h g-1at 500 mA g-1) and a remarkable rate capability(243.9 mA h g-1at 8 A g-1).Moreover,the full batteries based on the LFT/C/1.0G symmetric electrode demonstrate a reversible capacity of 117.0 mA h g-1after 100 cycles at 50 mA *** study presents useful insights into developing cost-effective DRX cathodes with durable and fast lithium storage.

关键词： 1D structure Disordered rock salt Li2FeTiO4 Graphene Lithium-ion battery electrode Rapid ion/electron transport

Why is China Promoting Economic Globalization?A Leadership Theory of Globalization

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China & World Economy 2025年第1期33卷 1-35页

作者： Meixin Guo David Daokui Li Kun lang Academic Center for Chinese Economic Practice and Thinking School of Social ScienceTsinghua UniversityChina School of Marxism Tsinghua UniversityChina

This article proposes a leadership theory of globalization to explain how economic globalization occurs and evolves,and why China wants to take a leading role in *** theory posits that an economy equipped with advanced industrial technology,a substantial domestic market,and robust institutional capacity is more likely to take the lead in driving economic *** advantages in high-tech industries position an economy favorably within the global value chains,maximizing its benefits from economic globalization.A large domestic market can entice other countries to agree to open their markets *** capacity enables governments to deter opposition to globalization from those disadvantaged by economic *** paper presents studies of historical cases of economic globalization and provides a three-stage model of *** argues that China has been gaining on three fronts in recent decades and is therefore willing to promote economic globalization.

关键词： economic globalization institutional advantage leadership market advantage technological advantage

Assessing ground stability of a vertical backfilled stope considering creep behaviors of surrounding rocks

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Journal of Rock Mechanics and Geotechnical Engineering 2025年第1期17卷 187-199页

作者： Ruofan Wang lang Liu Mengbo Zhu Huafu Qiu Bingbing Tu Huisheng Qu Hao Cui Faculty of Energy Engineering Xi’an University of Science and TechnologyXi’an710054China Key Laboratory of Western Mines and Hazards Prevention Ministry of Education of ChinaXi’an710054China Faculty of Science Xi’an University of Science and TechnologyXi’an710054China PowerChina Huadong Engineering Corporation Limited Hangzhou311122China

Backfill is often employed in mining operations for ground support,with its positive impact on ground stability acknowledged in many underground ***,existing studies have predominantly focused only on the stress development within the backfill material,leaving the influence of stope backfilling on stress distribution in surrounding rock mass and ground stability largely ***,this paper presents numerical models in FLAC3D to investigate,for the first time,the time-dependent stress redistribution around a vertical backfilled stope and its implications on ground stability,considering the creep of surrounding rock *** the Soft Soil constitutive model,the compressibility of backfill under large pressure was *** is found that the creep deformation of rock mass exercises compression on backfill and results in a less void ratio and increased modulus for fill *** compacted backfill conversely influenced the stress distribution and ground stability of rock mass which was a combined effect of wall creep and compressibility of *** the increase of time or/and creep deformation,the minimum principal stress in the rocks surrounding the backfilled stope increased towards the pre-mining stress state,while the deviatoric stress reduces leading to an increased factor of safety and improved ground *** improvement effect of backfill on ground stability increased with the increase of mine depth and stope height,while it is also more pronounced for the narrow stope,the backfill with a smaller compression index,and the soft rocks with a smaller viscosity ***,the results emphasize the importance of minimizing empty time and backfilling extracted stope as soon as possible for ground *** of filling gap height enhances the local stability around the roof of stope.

关键词： Ground stability Time dependency Creep Surrounding rocks Backfilled stope

Impacts of emission reduction and meteorological conditions on air quality improvement from 2016 to 2020 in the Northeast Plain,China

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Journal of Environmental Sciences 2025年第5期151卷 484-496页

作者： Xueling Yang Qiyuan Wang lang Liu Jie Tian Hailing Xie Luyao Wang Yue Cao Steven Sai Hang Ho Key Laboratory of Aerosol Chemistry and Physics State Key Laboratory of Loess and Quaternary GeologyInstitute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China Xi’an Institute for Innovative Earth Environment Research Xi’an 710061China National Observation and Research Station of Regional Ecological Environment Change and Comprehensive Management in the Guanzhong Plain Xi’an 710061China College of Meteorology and Oceanography National University of Defense TechnologyChangsha 410073China Division of Atmospheric Sciences Desert Research InstituteRenoNV 89512USA

The Northeast Plain in China ranks among the top five regions that have been significantly impacted by haze *** effectively control pollution,it is crucial to accurately assess the effects of emission reduction *** this study,we analyzed surveillance data and found substantial decreases(ranging from 19.0%to 50.1%)in average annual mass concentrations of key pollutants(such as CO,SO_(2),NO_(2),and PM_(2.5))in the Northeast Plain from 2016 to *** precisely determine the contributions of meteorological conditions and emission reductions to the improvement of air quality in the Northeast Plain,we conducted three scenario *** comparing source emissions in December 2016 and 2020 using the WRF-Chem model(except for SO_(2)),we observed significant reductions of 21.3%,8.8%,and 9.8%in mass concentrations of PM_(2.5),NO_(2),and CO,respectively,from 2016 to *** highlights the essential role that meteorological conditions play in determining air quality in the Northeast ***,further reducing source emissions by 30%in December 2016 resulted in subsequent reductions of 25.3%,29.0%,4.5%,and 30.3%in mass concentrations of PM_(2.5),SO_(2),NO_(2),and CO,respectively,under the same meteorological ***,source emission reduction was effective for PM_(2.5),SO_(2),and CO,but not for NO_(2).The improvement in air quality in the Northeast Plain from 2016 to 2020 can be attributed to the combined effects of improved meteorological conditions and reduced pollution sources.

关键词： Air quality Emission reduction Meteorological conditions The Northeast Plain WRF-Chem

Optimization of production well patterns for natural gas hydrate reservoir: Referring to the results from production tests and numerical simulations

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China Geology 2025年第1期8卷 39-57页

作者： lang-feng Mu Hao-tian Liu Chi Zhang Yi Zhang Hai-long Lu School of Earth and Space Sciences Peking UniversityBeijing 100871China Beijing International Center for Gas Hydrate School of Earth and Space SciencesPeking UniversityBeijing 100871China Chinese Academy of Geological Sciences China Geological SurveyMinistry of Natural Resources Beijing 100037China College of Engineering Peking UniversityBeijing 100871China National Engineering Research Center of Natural Gas Hydrate Exploration and Development Guangzhou 511458China China National Oil and Gas Exploration and Development LTD Corporation Petro-ChinaBeijing 100034China

Natural gas hydrate is a clean energy source with substantial resource *** contrast to conventional oil and gas,natural gas hydrate exists as a multi-phase system consisting of solids,liquids,and gases,which presents unique challenges and complicates the mechanisms of seepage and *** domestic and international natural gas hydrate production tests typically employ a single-well production *** this approach has seen some success,it continues to be hindered by low production rates and short production ***,there is an urgent need to explore a new well network to significantly increase the production of a single *** paper provides a comprehensive review of the latest advancements in natural gas hydrate research,including both laboratory studies and field *** further examines the gas production processes and development outcomes for single wells,dual wells,multi-branch wells,and multi-well systems under conditions of depressurization,thermal injection,and CO_(2) *** this basis,well types and well networks suitable for commercial exploitation of natural gas hydrate were explored,and the technical direction of natural gas hydrate development was *** study shows that fully exploiting the flexibility of complex structural wells and designing a well network compatible with the reservoir is the key to improving production from a single ***,multi-well joint exploitation is identified as an effective strategy for achieving large-scale,efficient development of natural gas hydrate.

关键词： Gas Hydrate Production Depressurization Heat Injection Replacement Multi-Branch Well Well patterns Hydrate exploration engineering

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What is the role of nonalcoholic fatty liver disease in pulmonary carcinoma development?

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World Journal of Gastroenterology 2025年第5期31卷 7-12页

作者： Qin Pan Qing-Yang Xu lang-Hua Zhang Ya-Fang He Shanghai Institute of Pediatric Research Shanghai Key Laboratory of Pediatric Gastroenterology and NutritionXinhua HospitalShanghai Jiao Tong UniversitySchool of MedicineShanghai 200092China Department of Gastroenterology Xinhua HospitalShanghai Jiao Tong UniversitySchool of MedicineShanghai 200092China School of Health Science and Engineering University of Shanghai for Science and TechnologyShanghai 200093China Department of Gastroenterology Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical UniversityLinhai 317000Zhejiang ProvinceChina School of Medical Technology Shanghai University of Medicine and Health SciencesShanghai 201318China Department of Pediatric Respiratory Xinhua HospitalShanghai Jiao Tong UniversitySchool of MedicineShanghai 200092China

This article summarizes the epidemiological characteristics and clinical manifest-ations of nonalcoholic fatty liver disease(NAFLD).The incidence of NAFLD has been increased dramatically and become the leading cause of chronic liver disease *** addition to its adverse outcomes of liver fibrosis,cirrhosis,and hepatocellular carcinoma,and related complications,NAFLD has recently been found to be associated with the high-risk extrahepatic carcinomas,such as various types of lung cancer(i.e.,lung adenocarcinoma,squamous cell carcinoma,and small cell lung cancer).The presence of hepatic steatosis also predisposes lung cancer to liver metastasis,but has better response to immune checkpoint *** other factors(i.e.,gender,smoking,etc.)are associated with NAFLD and lung cancer remains *** also comment on the reciprocal rela-tionships between NAFLD and components of metabolic *** meta-bolic syndrome components are suggested to facilitate lung cancer development via activating insulin/insulin-like growth factor *** addition,suppressed anti-tumor immunity and accelerated tumor progression could be attributed to the cell-specific metabolic reprogramming in condition of high-fat diet and related *** findings may reveal the role of NAFLD in pulmonary carcinoma and help develop new treatment strategies for this disease.

关键词： Nonalcoholic fatty liver disease Lung Cancer Adenocarcinoma Metabolic syndrome Component

Characteristics and phytotoxicity of hydrochar-derived dissolved organic matter:Effects of feedstock type and hydrothermal temperature

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Journal of Environmental Sciences 2025年第3期149卷 139-148页

作者： Qianqian lang Xuan Guo Chao Wang Lingyao Li Yufei Li Junxiang Xu Xiang Zhao Jijin Li Bensheng Liu Qinping Sun Guoyuan Zou Institute of Plant Nutrition and Resources Beijing Academy of Agriculture and Forestry SciencesBeijing 100097China

The dissolved organic matter(DOM)with high mobility and reactivity plays a crucial role in *** this study,the characteristics and phytotoxicity ofDOMreleased fromthe hydrochars prepared from different feedstocks(cowmanure,corn stalk and Myriophyllum aquaticum)under three hydrothermal carbonization(HTC)temperatures(180,200 and 220°C)were *** results showed that the hydrochars had high dissolved organic carbon content(20.15 to 37.65 mg/g)and its content showed a gradual reduction as HTC temperature *** fluorescent components including mixed substance of fulvic acid-like and humic acid-like substances(C1,30.92%-58.32%),UVA humic acid-like substance(C2,25.27%-29.94%)and protein-like substance(C3,11.74%-41.92%)were identified in hydrochar DOM by excitation emission matrix spectra coupled with parallel factor *** HTC temperature increased the relative proportion of aromatic substances(C1+C2)and humification degree of hydrochar DOM from cow manure,while it presented adverse effects on the hydrochar DOM from corn stalk and *** principal component analysis suggested that feedstock type and HTC temperature posed significant effects on the characteristics of hydrochar ***,seed germination test of all hydrochar DOM demonstrated that the root length was reduced by 8.88%-26.43%in contrast with control,and the germination index values were 73.57%-91.12%.These findings provided new insights into the potential environmental effects for hydrochar application in soil.

关键词： Hydrochar Hydrothermal temperature Dissolved organic matter Excitation emission matrix Parallel factor analysis Phytotoxicity