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Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

Chinese Physics C 2024年第8期48卷 6-33页

作者： m.Ablikim m.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya K.Begzsuren N.Berger m.Berlowski m.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen m.L.Chen S.J.Chen S.L.Chen S.m.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng K.Fischer m.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.m.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong m.Y.Dong X.Dong m.C.Du S.X.Du Z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna m.Greco m.H.Gu Y.T.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo m.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.L.Han T.T.Han X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou X.T.Hou Y.R.Hou Z.L.Hou B.Y.Hu H.m.Hu J.F.Hu T.Hu Y.Hu G.S.Huang K.X.Huang L.Q.Huang X.T.Huang Y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche m.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.B.Jiang P.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin m.Q.Jing X.m.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki X.L.Kang X.S.Kang m.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf m.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.lane P.Larin L.Lavezzi T.T.Lei Z.H.Lei H.Leithoff m.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.m.Li F.Li G.Li H.Li H.B.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li K.Li L.J.Li L.K.Li Lei Li m.H.Li P.R.Li Q.m.Li Q.X.Li R.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Y.Li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner mongolia University Hohhot 010021China Institute of modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKm angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis CP-even fraction

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Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population

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Hepatobiliary & Pancreatic Diseases International 2018年第4期17卷 330-335页

作者： Fabiola rabelo Jose Tadeu Stefano Ana mercedes Cavaleiro Rodrigo Vieira Costa Lima Daniel Ferraz de Campos mazo Flair Jose Carrilho maria Lúcia Correa-Giannellac Claudia P.Oliveiraa Departamento de Gastroenterologia Faculdade de Medicina FMUSPUniversidade de Sao PauloSao PauloSPBrazil Hospital das Clinicas HCFmUSP Departamento de GastroenterologiaLIM07Faculdade de MedicinaUniversidade de Sao PauloSao PauloSPBrazil Laboratório de Carboidratos e Radioimunensaio LIM18Hospital das Clinicas HCFMUSP(LIM07)Faculdade de MedicinaUniversidade de Sao PauloSao PauloBrazil Programa de Pos-Graduacao em medicina Universidade Nove de Julho(UNINOVE)Sao PauloBrazil

Background: Oxidative stress has been implicated in the progression of severe forms of non-alcoholic fatty liver disease(NAFLD). NADPH oxidase produces reactive oxygen species. In the present study, we investigated for the first time two single nucleotide polymorphisms(SNPs) in the regulatory region of genes encoding NADPH oxidase 4(NOX4) and p22 phox(CYBA) in ***: A total of 207 biopsy-proven NAFLD patients [simple steatosis(n = 27); nonalcoholic steatohepatitis(NASH)(n = 180)] were evaluated. Genomic DNA was extracted from peripheral blood cells, and polymorphisms in CYBA(unregistered) and NOX4(rs3017887) were determined by direct sequencing of ***: Associations of CYBA-675 T/A with high-density lipoprotein(HDL)(TT vs TA vs AA; P morphisms in the NOX4 gene, NOX4(rs3017887) CA + AA genotypes was significant associated with alanine aminotransferase(ALT)(CA + AA vs CC; P = 0.02). However, there was no association of SNPs in the CYBA and NOX4 genes encoding the NADPH oxidase system proteins and the presence of NASH. Regarding the clinical results, it was observed that the most advanced degrees of fibrosis occurred in patients diagnosed with type 2 diabetes mellitus(66.9% vs 37.5%, P more obese(32.2 vs 29.0 kg/m2,P m glucose and insulin levels increased significantly in the presence of ***: There were associations between the presence of the allele A in the NOX4 SNP and a higher concentration of ALT in the NAFLD population; between the presence of the AA genotype in the polymorphism of the CYBA-675 T/A CYBA gene and a higher level of TGL and lower HDL in NASH patients. The presence of metabolic syndrome was associated with advanced degrees of fibrosis in NAFLD patients.

关键词： Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Genetic polymorphism metabolic syndrome

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EGR1 is essential for transcriptional regulation of BmPR2

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American Journal of molecular Biology 2011年第3期1卷 131-139页

作者： Radhika Gaddipati James D. West James E. Loyd Thomas Blackwell Kirsten A. lane Nicole m. lane Kirk B. lane 不详

In this study, RLm-RACE was used to identify the transcriptional start site 387 bp upstream of the translational start. Evolutionarily conserved transcription factor binding sites were identified, and a series of luciferase reporter constructs driven by BmPR2 promoter elements used to determine their functional relevance. We found the promoter area from 983 bp to 90 bp upstream of the transcriptional start gave maximal activity, greater than longer constructs, with an area between 570 bp and 290 bp upstream of the transcriptional start containing an important repressor element. To characterize this repressor, we used a combination of EmSA, mutation of the EGR1 binding site, transfection with EGR1 and NAB1 constructs, and mutation of the NAB1 binding site within the EGR1 protein. From this we conclude that EGR1 is essential to BmPR2 transcription, but that NAB1 binding to EGR1 causes it to act as a repressor.

关键词： Transcription BmPR2 Regulation EGR1 NAB1 Pulmonary Hypertension

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Atypical Hemolytic Uremic Syndrome in a Post-COVID-19 Child: Its Differential Diagnosis with COVID-19, multisystemic Inflammatory Syndrome and Outcome

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Open Journal of Pediatrics 2022年第4期12卷 657-664页

作者： Fernanda Aparecida De Oliveira Peixoto Célia Regina malveste Ito André Luís Elias moreira Paulo Alex N. Silva mônica Oliveira Santos Isabela Jubé Wastowski Liana De medeiros machado Braga Vivian Da Cunha rabelo Lilian Carla Carneiro melissa Ameloti Gomes Avelino Department of Pediatrics Neonatal ICU of Clinical Hospital of Federal University of Goiás/Ebserh Goiania Brazil microorganism Biotechnology Laboratory of Institute of Tropical Pathology and Public Health Federal University of Goiás Goiania Brazil molecular Immunology Laboratory of Goiás State University Anápolis Brazil Pediatrics ICU of State Emergency Hospital Governor Otávio Lage of Siqueira Goiania Brazil Surgical Department of Pediatrics Medical School Federal University of Goiás Goiania Brazil

Pediatric multisystemic Inflammatory Syndrome (mIS-C) is one of the most severe manifestations of SARS-CoV-2 in pediatrics [1]. This is a report of mIS-C with clinical presentation in infants with atypical Hemolytic U... 详细信息

关键词： mISC COVID-19 aHUS Children Critical Care

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Extragastric manifestations of Helicobacter pylori infection: Possible role of bacterium in liver and pancreas diseases

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World Journal of Hepatology 2015年第30期7卷 2968-2979页

作者： Elizabeth mA rabelo-Goncalves Bruna m Roesler Jose mR Zeitune Laboratory of Gastroenterology and Hepatology Center of Diagnosis of Digestive DiseasesState University of CampinasCampinasSao Paulo 13083-878Brazil Department of Internal medicine Faculty of Medical SciencesState University of CampinasCampinasSao Paulo13083-887Brazil

Helicobacter pylori(H. pylori) is an ancient microorganism that has co-evolved with humans for over 60000 years. This bacterium typically colonizes the human stomach and it is currently recognized as the most common infectious pathogen of the gastroduodenal tract. Although its chronic infection is associated with gastritis, peptic ulcer, dysplasia, neoplasia, mALT lymphoma and gastric adenocarcinoma, it has been suggested the possible association of H. pylori infection with several extragastric effects including hepatobiliary and pancreatic diseases. Since a microorganism resembling H. pylori was detected in samples from patients with hepatobiliary disorders, several reports have been discussed the possible role of bacteria in hepatic diseases as hepatocellular carcinoma, cirrhosis and hepatic encephalopathy, nonalcoholic fatty liver disease and fibrosis. Additionally, studies have reported the possible association between H. pylori infection and pancreatic diseases, especially because it has been suggested that this infection could change the pancreatic physiology. Some of them have related a possible association between the microorganism and pancreatic cancer. H. pylori infection has also been suggested to play a role in the acute and chronic pancreatitis pathogenesis, autoimmune pancreatitis, diabetes mellitus and metabolic syndrome. Considering that association of H. pylori to liver and pancreas diseases needs further clarification, our work offers a review about the results of some investigations related to the potential pathogenicity of H. pylori in these extragastric diseases.

关键词： Hepatocellular carcinoma Cirrhosis Hepaticencephalopathy Helicobacter pylori Nonalcoholic fattyliver disease Fibrosis Pancreatitis Pancreatic cancer Diabetes mellitus metabolic syndrome

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mechanism of polymer adsorption on shale surfaces: Effect of polymer type and presence of monovalent and divalent salts

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Petroleum 2017年第3期3卷 384-390页

作者： Sudiptya Banerjee Zaid R.Abdulsattar Kaylaychi Agim Robert H.lane Berna Hascakir Texas A&m University United States

This paper studies the adsorption behavior of representative guar-based polymers onto the surface of source rock outcrop samples to provide a better picture of the interaction(s)of polymers with these *** samples from the Barnett,Eagle Ford,and marcellus shales were collected,analyzed for mineralogy and total organic content,and then exposed to different polymer solutions under elevated temperature and moderately elevated *** of these polymer solutions were measured before and after exposure to the rock samples to establish a correlation between polymer adsorption and rock mineralogy and/or organic *** indicate a direct correlation between polymer adsorption and both rock *** polymers are shown to be more prone to adsorption onto the surface of the rock than non-ionic *** results from this work establish that fluid-rock interactions are significant and that further research regarding shale polymer interactions and its effects on hydrocarbon production is needed with representative downhole shale samples given the trends now shown with outcrop samples.

关键词： adsorption polymer salts

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Correlation between an Independent Electronic Health Record &External Ranking of Children’s Hospitals

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Health 2021年第2期13卷 81-89页

作者： lane F. Donnelly David Scheinker Natalie m. Pageler Andrew Y. Shin Lucile Packard Children’s Hospital Stanford Stanford Children’s Health Stanford California USA Department of Pediatrics School of Medicine Stanford University Stanford California USA Department of Radiology School of Medicine Stanford University Stanford California USA

Introduction: To evaluate the correlation between the presence of an independent EHR (compared to a shared EHR system within an adult hospital system) and an externally-derived third party ranking of children’s hospitals. methods: Children’s hospitals that ranked in the top fifty of the 2019-2020 US News and World Report (USNWR) were included in the analysis. The mean and median ranking of children’s hospitals with independent versus a shared EHR was evaluated. The 2019-2020 USNWR rankings of the top twenty adult hospitals in the United States were then evaluated. For each children’s hospital with an associated adult hospital that was both ranked, it was noted as to whether the EHR for the children’s hospital was independent or shared and statistical differences in rankings compared. Results: Among the top 50 children’s hospitals included, the median USNWR ranking for hospitals was statistically different with an independent EHR than with a shared EHR (13 vs. 30.0) (p = 0.002). The 21 top ranked adult hospitals were associated with 17 children’s hospitals ranked in the top 50. The median ranking for those with an independent EHR was statistically different for those with independent EHR versus shared EHR (7 vs. 28) (p = 0.002). Conclusion: Children’s hospitals with an independent EHR are associated with higher scores on an independent external ranking of hospital quality compared to those which share an EHR with a partner adult hospital.

关键词： Electronic Health Record Quality Pediatrics

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污泥龄对活性污泥处理微量磺胺类药物的影响

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重庆大学学报（自然科学版） 2012年第6期35卷 63-71页

作者：杨程郭劲松 Belinda S.m.Sturm Rachael F.lane Craig D.Adams Ray E.Carter 重庆大学城市建设与环境工程学院重庆400045 关国堪萨斯大学土木建筑与环境工程学院美国堪萨斯州劳伦斯66045

为了研究污泥龄对活性污泥系统处理微量磺胺类药物(5μg/L)的影响,共运行了4个试验室规模(3L)的序批式活性污泥反应器(SBR),其污泥龄分别为2、8、14、20d。批次摇瓶试验通过设置3个工况(正常运行,加入生物抑制剂,无微生物)来讨论在1个... 详细信息

为了研究污泥龄对活性污泥系统处理微量磺胺类药物(5μg/L)的影响,共运行了4个试验室规模(3L)的序批式活性污泥反应器(SBR),其污泥龄分别为2、8、14、20d。批次摇瓶试验通过设置3个工况(正常运行,加入生物抑制剂,无微生物)来讨论在1个运行周期(8h)中对浓度为5μg/L磺胺甲恶唑的吸附作用、生物降解作用和挥发损失。试验结果显示对磺胺甲恶唑的总去除量为2.14±0.60μg/g SS,吸附作用占总去除量的63%;磺胺嘧啶为1.14±0.63μg/g SS,83%;磺胺间二甲氧为2.33±0.67μg/g SS,35%;磺胺甲基嘧啶为2.45±0.85μg/g SS,55%;磺胺类药物的去除效果与污泥的污泥龄有着非常显著的关系(p<0.02)。通过运行加入磺胺甲恶唑(进水5μg/L)的反应器60d,4个反应器对磺胺甲恶唑的平均去除率分别为10%、41%、51%、58%,处理效果随着污泥龄的增加而变好,同时单位污泥去除率随着污泥龄的增加而降低,SRT=2d的反应器由于存在大量的丝状菌,使得单位污泥对磺胺甲恶唑去除率大大高于其他3个反应器。通过分子生物学分析,发现微生物群落结构的变化不大,从而说明了影响磺胺类药物处理效果的主要因素在于更强的吸附能力,更高的污泥浓度。

关键词： DGGE活性污泥系统磺胺类抗生素磺胺甲恶唑污泥龄生物降解生物吸附

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The Use of PCA3 Can Reduce the Number of Prostate Biopsies Performed in a Community-Based Urologic Practice

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Open Journal of Urology 2013年第5期3卷 200-205页

作者： Bradley m. Boelkins Christopher m. Whelan Richard J. Kahnoski Jonathan Todd Bolthouse Brian R. lane michigan State University East Lansing USA

Purpose: It is now generally accepted that PSA screening identifies many prostate cancers that are low-risk and may not need treatment. PCA3 is a prostate cancer-specific marker with improved diagnostic accuracy when compared with PSA in research studies. It remains unknown whether PCA3 testing can reduce the unnecessary diagnosis and treatment of prostate cancer in routine practice. We evaluated whether the use of PCA3 in clinical practice decreases the number of biopsies being performed in response to PSA testing. methods: 64 consecutive patients undergoing PCA3 measurement in a single community-based urology practice were analyzed for rates of biopsy performance and prostate cancer detection. Results: median PSA was 5.0 (range: 0.4 - 38.6) and 50% had undergone prior biopsy without evidence of cancer. median PCA3 score was 13.6 (range: 1.6 - 133.0) with 14 patients having an elevated PCA3 (>35). Prostate biopsy was avoided in 50 of 64 patients (78%). Of the 11 patients undergoing biopsy for abnormal PCA3, 7 had prostate cancer (64%). At >2-year median follow-up, 39 of the remaining 50 patients (78%) avoided subsequent biopsy. Only 5 prostate cancers were diagnosed during follow-up. Conclusions: When used in routine clinical practice, PCA3 appears to reduce the number of biopsies being performed in response to elevated PSA. Given the increasing interest in strategies to reduce unnecessary prostate cancer diagnosis and treatment, this FDA-approved and widely-available molecular test appears to achieve these goals. Further testing will clarify the role of PCA3 in initial and subsequent prostate cancer screening paradigms.

关键词： Prostate Cancer Prostate Cancer Antigen 3 (PCA3) Prostate Biopsy

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microstructures in a carburized steel after isothermal pearlitic treatment

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Journal of materials Science & Technology 2023年第29期160卷 66-75页

作者： J.Abraham mathews H.Farahani J.Sietsma R.H.Petrov m.G.mecozzi m.J.Santofimia Department of materials Science and Engineering Delft University of TechnologyMekelweg 22628 CDDelftThe Netherlands Tata Steel Research&Development IJmuidenThe Netherlands Department of Electromechanical Systems and Metal EngineeringGhent UniversityTech Lane Ghent Science park-Campus A ZwijnaardeTechnologiepark 46Belgium

The influence of carbon concentration variations on pearlite formation(20 h at 600℃)in a case-carburized steel is *** resultant microstructure shows three distinct regions:carburized case,a transition region,and the original *** microstructural transition from the case to the core regions is observed to be relatively *** investigated region of the carburized case(0.9 wt.%C)con-tains two types of pearlite:ferrite+cementite and ferrite+m_(23)C_(6),where the pearlitic aggregate with m_(23)C_(6)shows faster formation *** kinetics of pearlite formation in the transition region(0.3 wt.%C)is very slow and is observed with only m_(23)C_(6)*** around 40%austenite decomposes into pearlite in the transition region,which,in comparison to the carburized case region of 0.9 wt.%C is a fraction that is lower by a factor of *** is absent in the investigated core region(0.16 wt.%C).The microstructure in this region is predominantly martensite and pro-eutectoid ferrite,with a fraction of ferrite well below the equilibrium *** formation in this region is limited by the redistribution of mainly Ni,mn,and Cr,and their resulting solute drag effect on the austenite/ferrite interface.A ther-modynamic and kinetic argumentation of these observations is provided with the help of thermodynamic data,precipitation simulations,and a general mixed-mode Gibbs energy balance model.

关键词： Pearlite formation Carburized steel m 2_(3)C_(6)carbide Kinetics Solute drag

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