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Outcome prediction value of National Early Warning Score in septic patients with community-acquired pneumonia in emergency department: A single-center retrospective cohort study

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World Journal of Emergency Medicine 2020年第4期11卷 206-215页

作者： Hai-jiang Zhou Tian-fei lan Shu-bin Guo Emergency Medicine Clinical Research Center Beijing Chao-yang HospitalCapital Medical University&Beijing Key Laboratory of Cardiopulmonary Cerebral ResuscitationBeijingChina Department of Allergy Beijing Shijitan HospitalCapital Medical UniversityBeijingChina

BACKGROUND:To evaluate the accuracy of National Early Warning Score(NEWS)in predicting clinical outcomes(28-day mortality,intensive care unit[ICU]admission,and mechanical ventilation use)for septic patients with community-acquired pneumonia(CAP)compared with other commonly used severity scores(CURB65,Pneumonia Severity Index[PSI],Sequential Organ Failure Assessment[SOFA],quick SOFA[qSOFA],and Mortality in Emergency Department Sepsis[MEDS])and admission lactate ***:Adult patients diagnosed with CAP admitted between January 2017 and May 2019 with admission SOFA≥2 from baseline were *** characteristics were *** primary outcome was the 28-day mortality after admission,and the secondary outcome included ICU admission and mechanical ventilation *** prediction value of parameters above was compared using receiver operating characteristics(ROC)*** regression analyses were carried out to determine the risk factors for the 28-day ***-Meier survival curves were plotted and compared using optimal cut-off values of qSOFA and ***:Among the 340 enrolled patients,90 patients were dead after a 28-day follow-up,62 patients were admitted to ICU,and 84 patients underwent mechanical *** single predictors,NEWS achieved the largest area under the receiver operating characteristic(AUROC)curve in predicting the 28-day mortality(0.861),ICU admission(0.895),and use of mechanical ventilation(0.873).NEWS+lactate,similar to MEDS+lactate,outperformed other combinations of severity score and admission lactate in predicting the 28-day mortality(AUROC 0.866)and ICU admission(AUROC 0.905),while NEWS+lactate did not outperform other combinations in predicting mechanical ventilation(AUROC 0.886).Admission lactate only improved the predicting performance of CURB65 and qSOFA in predicting the 28-day mortality and ICU ***:NEWS could be a valuable predictor in septic patients with CAP in emergency depa

关键词： Community-acquired pneumonia Sepsis National Early Warning Score(NEWS) Intensive care unit Emergency departments

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Potential etiopathogenesis of seventh day syndrome following living donor liver transplantation:ischemia of the graft?

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Hepatobiliary & Pancreatic Diseases International 2010年第1期9卷 22-26页

作者： lan, Xiang Li, bo Wang, Xiao-fei Wei, Yong-Gang Yan, Lu-Nan Zhao, Ji-Chun Sichuan Univ W China Hosp Div Liver Transplantat Chengdu 610041 Peoples R China Sichuan Univ W China Hosp Div Vasc Surg Chengdu 610041 Peoples R China

BACKGROUND: Seventh-day syndrome (7DS) is an early serious complication following liver transplantation with a high mortality because of its unknown etiopathogenesis. This study aimed to analyze the potential etiopathogenesis of 7DS. METHODS: A retrospective analysis of 98 consecutive living donor liver transplants performed from 2001 to 2007 at our center revealed that 5 patients had suffered from 7DS; their age, MELD score, portal vein inflow and other parameters were compared with those of the other recipients. RESULTS: The 5 patients showed common features: (a) initial uneventful recovery, and a dramatic rise of serum liver enzyme levels I to 2 weeks later; (b) decreased inflow in the portal vein accompanied by augmentation of serum creatinine and urea nitrogen level; and (c) serial liver biopsy findings of apoptosis and ischemic necrosis of hepatocytes. Four of the 5 patients died. Age, waiting time to transplantation, MELD score, operation time, cold ischemic time, portal interceptive time and diameter of the portal vein were not significantly different between the 2 groups, but a difference was found in the flow rate of the portal vein (t=3.234, P<0.001). CONCLUSIONS: The 5 patients suffered from a decreased portal vein inflow, ischemic liver necrosis, and renal failure. Hence, hypoperfusion of the liver graft was considered to be the etiopathogenesis of 7DS, for which, however sufficient evidence is lacking. More studies of 7DS are needed.

关键词： seventh-day syndrome living donor liver transplantation ischemic hepatitis etiopathogenesis hepatocellular necrosis

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Microstructural evolution and stress state related to mechanical properties of electron beam melted Ti-6Al-4V alloy modified by laser shock peening

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Journal of Materials Science & Technology 2020年第15期47卷 153-161页

作者： Liang lan Xinyuan Jin Shuang Gao bo He Yonghua Rong Research Center of High-temperature Alloy Precision Forming School of Material EngineeringShanghai University of Engineering ScienceShanghai 201620China School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China

This work characterizes microstructural evolutions of electron beam melted(EBM) Ti-6 Al-4 V alloy modified via laser shock peening(LSP).The depth stress distribution and tensile properties of EBM Ti-6 Al-4 V alloy were measured before and after *** results indicate that microstructure consists of β phase with 7.2%±0.4% vol.% and balance α lamellar in EBM sample,and the α lamella was refined into nano-equiaxed grains and submicro-equiaxed grains after *** dominant refinement mechanism is revealed during *** faults were found in the LSP-treated sample,and their corresponding planes were determined as(0001) basal plane,(1010) prismatic plane,and(1011) pyramidal plane obtained by high resolution transmission electron *** subgrains and high-angle grains formed during dynamic recrystallization were identified by selected area electron diffraction *** LSP treatment produces a significantly residual compressive stress approximately-380 MPa with the depth of compressive stress layer reaching 450 μ*** and elongation of the EBM sample were significantly increased after *** strength and ductility enhancements are attributed to compre s sive stress,grain refinement and grain gradient distribution of α phase.

关键词： Electron beam melting Ti-6Al-4V alloy Laser shock peening Microstructural evolution Stress state Mechanical properties

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A More Restrictive Upper bound for the Bare Pomeron Intercept

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Chinese Physics Letters 1998年第2期15卷 81-82页

作者： HE bo PENG fei ZHU Wei Department of Applied Physics Shanghai Jiaotong UniversityMinhang CampusShanghai 200240 Department of Physics East China Normal UniversityShanghai 200062

By studying the properties of the modified Gribov-Levin-Ryskin evolution equation which incorporates both shadowing and antishadowing effects,the more restrict upper bound is set for the bare pomeron intercept in the ... 详细信息

关键词： uniformly distribute restrict

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Influence of multiple laser shock peening treatments on the microstructure and mechanical properties of Ti-6Al-4V alloy fabricated by electron beam melting

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International Journal of Minerals,Metallurgy and Materials 2022年第9期29卷 1780-1787页

作者： Liang lan Ruyi Xin Xinyuan Jin Shuang Gao bo He School of Material Engineering Shanghai University of Engineering ScienceShanghai 201620China Research Center of High-temperature Alloy Precision Forming Shanghai University of Engineering ScienceShanghai 201620China

Laser shock peening(LSP)is an attractive post-processing method to tailor surface microstructure and enhance mechanical performances of additive manufactured(AM)*** effects of multiple LSP treatments on the microstructure and mechanical properties of Ti-6Al-4V part produced by electron beam melting(EBM),as a mature AM process,were studied in this ***,surface topography,residual stress,and tensile performance of EBM-manufactured Ti-6Al-4V specimens were systematically analyzed subjected to different LSP *** distribution of porosities in EBM sample was assessed via X-ray computed *** results showed that EBM samples with two LSP treatments possessed a lower porosity value of 0.05%compared to the value of 0.08%for the untreated *** strength of EBM samples with two LSP treatments was remarkably raised by 12%as compared with the as-built *** grains ofαphase were refined in near-surface layer,and a dramatic increase in the depth and magnitude of compressive residual stress(CRS)was achieved in EBM sample with multiple LSP *** grain refinement ofαphase and CRS with larger depth were responsible for the strength enhancement of EBM samples with two LSP treatments.

关键词： additive manufacturing laser shock peening electron beam melting residual stress Ti-6Al-4V alloy mechanical properties

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Periodic Solutions of a Delayed Predator-Prey Model with Stage Structure for Prey

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Acta Mathematicae Applicatae Sinica 2004年第2期20卷 323-332页

作者： RuiXu lan-sunChent fei-longHao DepartmentofMathematics InstituteofShijiazhuangMechanicalEngineeringShijiazhuang050003China AcademyofMathematicsandSystemsScience CASBeijing100080China

A periodic predator-prey model with stage structure for prey and time delays due to negative feed-back and gestation of predator is *** using Gaines and Mawhin's continuation theorem of coincidencedegree theory,sufficient conditions are derived for the existence of positive periodic solutions to the *** simulations are presented to illustrate the feasibility of our main result.

关键词： Stage structure predator-prey model time delay periodic solution

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Preparation and characterization of HMX/NH_(2)-GO composite with enhanced thermal safety and desensitization

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Defence Technology（防务技术） 2022年第11期18卷 2074-2082页

作者： Yu-lan Song Qi Huang bo Jin Ru-fang Peng State Key Laboratory of Environment-friendly Energy Materials School of Materials Science and EngineeringSouthwest University of Science and TechnologyMianyang621010China

To improve the safety of HMX,HMX/NH_(2)-GO composite was prepared with aqueous ammonia functionalized graphene oxide(NH_(2)-GO).The composite was characterized by SEM,Zeta potential,XPS,Raman spectrum,XRD,HPLC,DSC and BAM sensitivity *** results indicated that the functionalization with aqueous ammonia can enhance the interaction between GO and HMX,and more efficiently desensitize the *** optimal impact sensitivity of the HMX/NH_(2)-GO composite can be not less than 40 J,which is also the most insensitivity compared to the previous reports prepared by coating desensitization with non-energetic desensitized ***,the potential reason for the different impact and friction sensitivity was also discussed,which may bring a novel perspective to achieve the desensitization of energetic material.

关键词： HMX GO Ammonia Surface coating technology

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Fecal microbiota transplantation for Clostridium difficile infection in patients with ileal pouches

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Gastroenterology Report 2017年第3期5卷 200-207,I0002页

作者： Nan lan Jean Ashburn bo Shen Center for Inflammatory bowel Diseases Digestive Disease InstituteThe Cleveland Clinic FoundationClevelandOHUSA

Background:Clostridium difficile infection(CDI)in patients with ileal pouch-anal anastomosis(IPAA)has been increasingly *** aim of this study was to evaluate the outcome of fecal microbiota transplantation(FMT)in patients with pouch and ***:All consecutive patients that underwent FMT for CDI from 2012 to 2016 were extracted from our IRB-approved,prospectively maintained Registry of Pouch *** primary outcome was negative stool tests for Clostridium difficile after FMT and the secondary outcomes were symptomatic and endoscopic ***:A total of 13 patients were included in this study,with 10 being Caucasian males(76.9%).All patients had underlying ulcerative colitis for J pouch *** a mean of 2.8±0.8 courses of antibiotic treatments was given and failed,22 sessions of FMT were administered with an average of 1.7±1.1 sessions *** the 22 sessions,16 were given via pouchoscopy,4 via esophagogastroduodenoscopy and 2 via *** patients tested negative on *** polymerase chain reaction(PCR)after the initial FMT with a total of 7/12(58.3%)documented patients showed symptomatic improvements and 3/11(27.3%)patients showed endoscopic improvement according to the modified Pouchitis Disease Activity *** the follow-up of 1.2±1.1 years,there were a total of five patients(38.5%)that had recurrence after the successful initial treatment and four of them were successfully treated again with ***:FMT appeared to be effective in eradication of CDI in patients with ileal ***,FMT had a modest impact on endoscopic inflammation and recurrence after FMT and recurrence was common.

关键词： Clostridium difficile fecal microbiota transplantation ileal pouch pouchitis

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利用mtDNA信息分析陶寺古牛的起源驯化

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农业生物技术学报 2025年第1期33卷 92-103页

作者：张兴杨柳侯凌云凌飞向海赵兴波华南理工大学生物科学与工程学院佛山大学动物科技学院/广东省动物分子设计与精准育种重点实验室中国农业大学动物科学技术学院/畜禽生物育种全国重点实验室

作为最重要的家畜之一，普通牛（bos taurus）在中国的起源和传播模式受到广泛关注。本研究收集了来自黄河中游3个考古遗址的9个古代牛遗骸，提取古DNA进行PCR测序和系统发生分析，以探索中国家养牛的起源和传播。经2轮PCR实验获得4个... 详细信息

作为最重要的家畜之一，普通牛（bos taurus）在中国的起源和传播模式受到广泛关注。本研究收集了来自黄河中游3个考古遗址的9个古代牛遗骸，提取古DNA进行PCR测序和系统发生分析，以探索中国家养牛的起源和传播。经2轮PCR实验获得4个陶寺（距今4100年前）古牛527 bp的线粒体DNA（mitochondrial DNA, mtDNA）序列。单倍型划分结果显示，陶寺古牛存在4种单倍型，都属于家养普通牛T3和T4单倍群，证实中国普通牛起源于近东地区，4 100年前就已经被华北人群利用。此外，陶寺遗址丰富的单倍型数量提示陶寺遗址古代牛群体具有较高的母系遗传多样性。群体间遗传分化指数FST（Fstatistics）分析和Median-Joining网络图表明，中国古代牛与现代东亚(FST=0.0164)及中国普通牛(FST=0.0066)均有密切的遗传关系，提示陶寺遗址古代牛群体可能是现代东亚和中国普通牛的重要母系祖先群体之一。本研究为解析我国的家牛起源和传播提供了分子遗传证据。

关键词：古代DNA 陶寺遗址普通牛起源

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One-pot synthesis of diarylimidazolium salts from 1H-imidazole

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Chinese Chemical Letters 2013年第9期24卷 773-776页

作者： Tai-Yong Lv Lei Yang Yin-Song Zhao fei-Jie Song Jing-bo lan Jing-Song You Ge Gao Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry

Diarylimidazolium salts （3） were directly synthesized starting from lH-imidazole （1） by a one-pot strategy using diaryliodonium salts as the arylating reagents, lH-Benzimidazole and 1H-1,2,4-triazole are suitable ... 详细信息

关键词： Diaryliodonium salt 1H-lmidazole Copper catalysis Diarylimidazolium saltNHC

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