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Associations between serum potassium and sodium levels and risk of hypertension： a community-based cohort study

Journal of Geriatric Cardiology 2015年第2期12卷 119-126页

作者： Lu XI Yong-Chen HAO Jing LIU Wei WANG Miao WANG Guo-Qi LI Yue QI Fan zhao Wu-Xiang XIE Yan LI Jia-Yi SUN Jun LIU lan-Ping qin Dong zhao Department of Epidemiology Beijing Anzhen Hospital Capital Medical University Beijing Institute of Heart Lung and Blood Vessel Diseases No. 2 AnzhenRoad Chaoyang District Beijing 100029 China

Objective Several studies have examined the relationships between dietary potassium and sodium and hypertension, but few have evaluated the association between serum potassium or sodium and risk of incident hypertension. We therefore investigated the associations between serum potassium and sodium and risk of incident hypertension in a Chinese community-based population. Methods A total of 839 normotensive individuals without cardiovascular disease from the Chinese Multi-Provincial Cohort Study who took part in the baseline examination in 2007-2008 and the follow-up survey in 2012-2013 were included in this study. Odds ratios （OR） and 95% confidence intervals （95%CI） for baseline serum potassium and sodium in relation to the risk of new-onset hypertension were evaluated using multivari- ate logistic regression models. Results During five years of follow-up, 218 （26.0%） individuals progressed to hypertension. Logistic re- gression adjusting for multiple confounders showed that every 1 mEq/L increment in baseline serum potassium level was associated with a 75% increased risk of hypertension （OR： 1.75; 95%CI： 1.01-3.04; P = 0.04）. Compared with adults with serum potassium level of 4.20-4.79 mEq/L, adults with level 〉 4.80 mEq/L had an 84% increased risk of hypertension （OR： 1.84; 95%CI： 1.14-2.96; P = 0.01）. There was no significant association between serum sodium and risk of hypertension （OR： 0.96; 95%CI： 0.89-1.04; P = 0.33）. Conclusions Base- line serum potassium level, but not baseline serum sodium level, was positively related to the risk of incident hypertension in the Chinese population.

关键词： Hypertension Potassium Serum Sodium

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Dynamic profile of ocular refraction in pediatric cataract patients after lens surgeries

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International Journal of Ophthalmology(English edition) 2019年第12期12卷 1839-1847页

作者： Zhen-Zhen Liu Er-Ping Long Duo-Ru Lin Lei Ye Yi-Fan Xiang Wang-Ting Li Xiao-Hang Wu Xu-Tu zhao Xiao-Ping Liu lan-qin zhao Xiu-Cheng Huang Tong-Yong Yu Hui Chen Jing-Jing Chen Ming-Xing Wu Hao-Tian Lin Wei-Rong Chen Yi-Zhi Liu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University

AIM: To study the change in ocular refraction in patients with pediatric cataracts(PCs) after lens extraction. METHODS: A total of 1258 patients who were undergoing cataract extraction with/without intraocular lens(IOL)implantation were recruited during preoperative examinations between Jan 2010 and Oct 2013. Patient ages ranged from 1.5 mo to 14y. Follow-ups were conducted at1 wk, 1, and 3 mo postoperatively and every 3 mo in the first year, then 6 mo thereafter. Ocular refraction [evaluated as spherical equivalent(SE)] and yearly myopic shift(YMS)were recorded and statistically analyzed among patients with age at surgery, baseline ocular refraction, gender,postoperative time and laterality(bilateral vs unilateral). RESULTS: By Dec 31st 2015, 1172 participants had been followed for more than 2y. The median follow-up period was 3y. The critical factors affecting the ocular refraction of PC patients were baseline ocular refraction, postoperative time for both aphakic and pseudophakic eyes. YMS grew most rapidly in young childhood and early adolescence. CONCLUSION: After lens surgeries, ocular refraction in PC patients shows an individual difference of *** concerns should be raising to monitor the rapid myopic shift at early adolescence of these patients.

关键词： pediatric cataract refraction intraocular lens myopic shift

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Enhanced rate capability and cycle stability of Ti2C MXene for sodium storage through an aniline molecules welding strategy

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Tungsten 2025年第1期7卷 161-171页

作者： Hao Chen Ya-qin Wang Dong-Ting Zhang Bei zhao Min-Peng Li Chen-Yang Li Tian-Peng Xu Mao-Cheng Liu State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals Lanzhou University of Technology School of Materials Science and Engineering Lanzhou University of Technology School of Computer and Communication Technology Lanzhou University of Technology

MXenes obtained significant attention in the field of energy storage devices due to their characteristic layered structure,modifiable surface functional groups,large electrochemically active surface,and regulable interlayer ***,the self-restacking and sluggish ions diffusion kinetics performance of MXenes during the alkali metal ions insertion/extraction process severely impedes their cycle stability and rate *** paper proposes an aniline molecule welding strategy for welding p-phenylenediamine（PPDA） into the interlayers of Ti2C through a dehydration condensation *** welded PPDA molecules can contribute pillar effect to the layered structure of *** pillar effect effectively maintains the structural stability during the sodium ions insertion/extraction process and effectively expands the interlayer spacing of Ti2C from 1.16 to 1.38 nm,thereby enhancing ions diffusion kinetics performance and improving the long-term cycle *** Ti2C-PPDA demonstrates outstanding Na+storage capability,exhibiting a specific capacity of 100.2 mAh·g-1at a current density of 0.1 A·g-1over 960 cycles and delivering a remarkable rate capability 81.2 mAh·g-1at a current density of 5 A·*** study demonstrates that expanding interlayer spacing is a promising strategy to enhance the Na+storage capacity and improve long-term cycling stability,which provides significant guidance for the design of two-dimensional Na+storage materials with high-rate capability and cycle stability.

关键词： Diffusion kinetics Expanding interlayer spacing Rate capability Sodium ions storage Ti2C

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Application of traditional Chinese medicine preparations among outpatients with coronary heart disease and its association with the guidelines-recommended medications

Application of traditional Chinese medicine preparations amo...

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第十三次全国心血管病学术会议

作者： GUO Xiang-yu,LIU Jun,LI Hong-juan Li,qin lan-ping,zhao Dong Capital Medical University Beijing Anzhen Hospital Beijing Institute of Heart,Lung and Blood Vessel Diseases.Beijing 100029, China

Objective To determine the application of traditional Chinese medicine preparations(TCMP) in the secondary prevention of coronary heart disease(CHD) and its association with the use of guidelines-recommended western *** A cross-sectional survey was conducted among 2803 CHD outpatients,a representative sample of *** general demographic data,disease histories,and information on drugs(including TCMP and western drugs) previously and currently

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Persistent alterations in gray matter in COVID-19 patients experiencing sleep disturbances:a 3-month longitudinal study

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Neural Regeneration Research 2025年第10期20卷 3013-3024页

作者： Kaixuan Zhou Gaoxiong Duan Ying Liu Bei Peng Xiaoyan Zhou Lixia qin Lingyan Liang Yichen Wei qingping Zhang Xiaocheng Li Haixia qin Yinqi Lai Yian Lu Yan Zhang Jiazhu Huang Jinli Huang Yinfei Ouyang Bolin Bin Mingming zhao Jun Liu Jianrong Yang Demao Deng Guangxi Key Laboratory of Special Biomedicine School of MedicineGuangxi UniversityNanningGuangxi Zhuang Autonomous RegionChina Department of Radiology the People’s Hospital of Guangxi Zhuang Autonomous RegionGuangxi Academy of Medical SciencesNanningGuangxi Zhuang Autonomous RegionChina Department of Sleep Medicine the People’s Hospital of Guangxi Zhuang Autonomous RegionNanningGuangxi Zhuang Autonomous RegionChina Department of Radiology The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Guangxi Clinical Research Center for Sleep Medicine the People’s Hospital of Guangxi Zhuang Autonomous RegionNanningGuangxi Zhuang Autonomous RegionChina

Sleep disturbances are among the most prevalent neuropsychiatric symptoms in individuals who have recovered from severe acute respiratory syndrome coronavirus 2 *** studies have demonstrated abnormal brain structures in patients with sleep disturbances who have recovered from coronavirus disease 2019(COVID-19).However,neuroimaging studies on sleep disturbances caused by COVID-19 are scarce,and existing studies have primarily focused on the long-term effects of the virus,with minimal acute phase *** a result,little is known about the pathophysiology of sleep disturbances in the acute phase of *** address this issue,we designed a longitudinal study to investigate whether alterations in brain structure occur during the acute phase of infection,and verified the results using 3-month follow-up data.A total of 26 COVID-19 patients with sleep disturbances(aged 51.5±13.57 years,8 women and 18 men),27 COVID-19 patients without sleep disturbances(aged 47.33±15.98 years,9 women and 18 men),and 31 age-and gender-matched healthy controls(aged 49.19±17.51 years,9 women and 22 men)were included in this *** COVID-19 patients with sleep disturbances were included in a longitudinal *** found that COVID-19 patients with sleep disturbances exhibited brain structural changes in almost all brain *** cortical thicknesses of the left pars opercularis and left precuneus were significantly negatively correlated with Pittsburgh Sleep Quality Index ***,we observed changes in the volume of the hippocampus and its subfield regions in COVID-19 patients compared with the healthy *** 3-month follow-up data revealed indices of altered cerebral structure(cortical thickness,cortical grey matter volume,and cortical surface area)in the frontal-parietal cortex compared with the baseline in COVID-19 patients with sleep *** findings indicate that the sleep disturbances patients had altered morphology in the cortical an

关键词： brain structure cortical gray matter volume cortical surface area cortical thickness hippocampus magnetic resonance imaging Pittsburgh Sleep Quality Index severe acute respiratory syndrome coronavirus 2 infections sleep disturbances sub-cortical volume

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An efficient and balanced feature pyramid network: shared-FPN

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Optoelectronics Letters 2025年

作者： Tian Sulong qin Longfei Pang Wenchao Gao Ying zhao Dexin School of Computer Science and Engineering， Tianjin University of Technology Tianjin Key Laboratory of Intelligence Computing and Novel Software Technology， Tianjin University of Technology

In the field of object detection， it is challenging to achieve a balance between neck complexity and accuracy. To address this issue， we propose an efficient and decoupled neck module called Shared-FPN(Shared Feature Pyramid Network). Our design aims to effectively address the trade-off between these two factors. Neck modules are crucial for effectively fusing multi-scale information in neural network models. However， traditional neck designs， with their single structure， have struggled to significantly improve detection performance. In recent years， the incorporation of neural architecture search techniques in neck design has led to an increase in model complexity. This trade-off between model complexity and detection performance highlights the need for more efficient neck design approaches. Not only does Shared-FPN not increase the number of model parameters and FLOPs， but it also can be easily ported to any of the detection models. It improves on PAFPN by using transposed convolution with a large convolution kernel as the upsampling module， designing spatial pyramidal pooling-fast downsampling(SPPFD) based on shared pooling， and designing shared convolution as the right part module. To evaluate the performance of Shared-FPN in object detection tasks， we conducted experiments on object detection datasets. The results show that Shared-FPN achieved excellent performance across all sizes. In particular， on the VOC 2012 dataset， which contains mostly large objects， Shared-FPN's mAP was improved by 11.2% compared to FPN with YOLOX-s as the detector. On the COCO dataset， which contains mostly small objects， Shared-FPN's mAP was improved by 7.8% compared to FPN and 7.1% compared to PAFPN with Faster RCNN as the detector. Shared-FPN can be easily inserted into any of the detectors for better performance in various scenarios， such as small， medium or large objects.

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基于景观生态学的乡村公园规划设计

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安徽农业科学 2017年第6期45卷 186-189页

作者：梅沁林敏赵书彬海南大学园艺园林学院海南海口570100 武汉科盟规划设计咨询有限公司湖北武汉430000

通过分析乡村景观建设的现状及需求,结合景观生态学最优景观格局(即集中与分散相结合的模式)理论,在尊重乡村原始景观格局,保留大型斑块及原始廊道系统的基础上,主张增加绿色廊道以及小型自然斑块,促进斑块边缘物质交流,构建适合乡村地... 详细信息

通过分析乡村景观建设的现状及需求,结合景观生态学最优景观格局(即集中与分散相结合的模式)理论,在尊重乡村原始景观格局,保留大型斑块及原始廊道系统的基础上,主张增加绿色廊道以及小型自然斑块,促进斑块边缘物质交流,构建适合乡村地区、符合生态性要求及可永续性发展的乡村公园,以期维持生态系统的稳定性,丰富景观生态多样性,增加乡土景观元素的参与性,减少建设过程中对乡村自然生态环境造成的破坏,为美丽乡村建设和乡村旅游发展提供设计理论参考。

关键词：乡村公园景观生态大集中小分散

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气虚证动物模型造模方法综述

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上海中医药大学学报 2004年第3期18卷 56-60页

作者：李军兰方肇勤上海中医药大学上海201203

查阅 1990年以来气虚证动物模型的造模方法的相关文献 ,按限制日摄食量法、单纯泻下法、疲劳法、烟熏法、化疗药物、X线照射、偏食苦味、耗气破气、苦寒泻下加耗气破气降气、食醋、手术、失血等分类进行综述 ,为开展气虚证实验研究奠定... 详细信息

查阅 1990年以来气虚证动物模型的造模方法的相关文献 ,按限制日摄食量法、单纯泻下法、疲劳法、烟熏法、化疗药物、X线照射、偏食苦味、耗气破气、苦寒泻下加耗气破气降气、食醋、手术、失血等分类进行综述 ,为开展气虚证实验研究奠定理论基础。

关键词：证侯气虚动物模型

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Quantitative reconstruction of salinity and precipitation changes in Central Asia over the past 3200 years using diatom and pollen records of lacustrine sediment in Aibi Lake of SW Junggar Basin

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Journal of Earth Science 2025年

作者： Long Pan Guoqiang Li Xiaoyan Wang Ming Jin Xinrong He Luo qin Zhong Wang Wenwei zhao Chunzhu Chen Yuanlu Liu Jin Yang Lele Shu Key Laboratory of Western China's Environmental Systems (Ministry of Education)， College of Earth and Environmental Sciences， lanzhou University College of Earth Sciences， Chengdu University of Technology School of Geographic Science， Nantong University Key Laboratory of land Surface Process and Climate Change in Cold and Arid Regions， Northwest Institute of Eco-Environment and Resources， Chinese Academy of Sciences

The response of lake environments in arid Central Asia to climate change during the Late Holocene over the centennial to millennial timescales remains contentious. The reason that primarily paleoenvironmental proxies interpreting diverse and the scarcity of accurate quantitative reconstruction records. In this study， we employed diatoms and pollen records from lacustrine sediment in the Aibi Lake of SW Junggar Basin to quantitatively reconstruct salinity and watershed precipitation amounts while exploring the associated forcing mechanism. The results indicate that Aibi Lake salinity varied between 2 g/L and 47 g/L during the Late Holocene period， indicating a generally brackish environment， and corresponding to prevailing Tryblionella granulata diatom in the lake basin. Westerly-dominated annual precipitation varied between 250 mm and 320 mm during the Late Holocene period in the basin， exhibiting a generally semi-arid environment and prevailing desert steppe vegetation. The Aibi Lake has a low salinity of average value of ～15 g/L. It exhibits elevated precipitation (average value of ～280 mm) during the periods of the Roman Warm Period (2900-1990 cal yr BP)， Dark Age Cold Period (1570-1140 cal yr BP)， and Little Ice Age (590-120 cal yr BP). The reconstructed precipitation and salinity exhibit a periodicity of ～200 years， which is consistent with the cycle of phase changes of the North Atlantic Oscillation (NAO) and Total Solar Irradiance (TSI). This correlation suggests that variations in NOA and TSI significantly influence the precipitation and salinity changes in Central Asia over centennial to millennial timescales.

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A Novel Drug Delivery Carrier Based on α-eleostearic Acid Grafted Hydroxyapatite Composite

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Journal of Bionic Engineering 2014年第1期11卷 125-133页

作者： Ting Cao Weili Tang Jingchan zhao Lulu qin Chunbo lan Key Laboratory of Synthetic and Natural Functional Molecular Chemistry of Ministry of Education Northwest University Xi' an 710069 P. R. China College of Chemistry & Material Science Northwest University Xi' an 710069 P. R. China

The purpose of this study is to explore and develop a novel biocompatibility drug delivery carrier for controllingontrolled drug release. The a-eleostearic acid grafted hydroxyapatite （a-ESA-g-HA） composite was synthesized by using silane coupling agent and characterized by Fourier Transformation Infrared Spectroscopy （FT-IR）, Thermal Gravimetric Analysis （TGA） and Scanning Electron Microscope （SEM）, respectively. The in vitro drug loading and controlled release behaviors of a-ESA-g-HA composite were investigated using ciprofloxacin as the model drug. The amount of ciprofloxacin loading and released was cal- culated by absorbance value which was determined by UV-Vis spectrophotometry at wavelength of 277 nm. The biocompatibility of a-ESA-g-HA composite was assessed by 3-（4,5）-dimethylthiahiazo（-z-yl）-3,5-di-phenytetrazoliumromide（MTT） assay, nuclear morphology and platelet adhesion. The results showed that the a-ESA-g-HA had nontoxic and good biocompatibility. According to the results mentioned above, the a-ESA-g-HA is an effective drug delivery carrier, which could increase drug loading capacity and control drug release, so further studies are necessary to evaluate clinical application and human health care.

关键词： a-eleostearic acid hydroxyapatite release biocompatibility composite

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