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良好FPGA信号完整性的实现方法

电子产品世界 2005年第11期 66-68+71页

作者： lalitha Oruganti Altera公司FPGA产品部高级技术行销经理

The Effects of Heat Shock on the D-Values of <i>Listeria monocytogenes</i>on Selected Seafood Matrices

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Advances in Microbiology 2015年第8期5卷 580-585页

作者： Michael V. Wood Aswathy sreedharan Rachael Silverberg Alina N. Balaguero Keith R. Schneider Department of Food Science and Human Nutrition University of Florida Gainesville FL USA

With more ready-to-eat foods and increased shelf-lives, prevention of Listeria monocytogenes contamination has become a necessity for the food industry. This study examined the effects of sublethal heat treatment on the decimal reduction time (D-values) of three L. monocytogenes serotypes (1/2a, 1/2b, 4c), and non-pathogenic L. innocua. The D70 (D-value at 70℃) values of heat-shocked (HS) and non-heat-shocked (NHS) Listeria grown in tryptic soy broth (TSB) were determined. The D70 values of HS L. monocytogenes serotype 1/2a and L. innocua were significantly higher compared to NHS cultures, although by 48 h, the values returned to NHS levels. When HS and NHS 1/2a and 1/2b were inoculated on crab meat and cooked shrimp, the D70 values of HS cultures were at least 2-fold higher, compared to when they were grown in TSB. This increase in heat resistance for the HS cultures may be attributed to the protective effect of the seafood matrix itself.

关键词： Listeria monocytogenes Ready-to-Eat Seafood Heat Shock D-Value

The impact of the cor on avirus disease 2019 Checkfol pandemic on elective urological procedures in Australia

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Asian Journal of Urology 2022年第1期9卷 35-41页

作者： Athul John Mustafa Mian Subhashaan sreedharan Arman AKahokehr Adelaide Medical School University of AdelaideAdelaideSAAustralia Melbourne Medical School University of MelbourneSt AlbansMelbourneVICAustralia Flinders University Bedford PorkSAAustralia

Objective:To investigate the changes in elective private urological procedures in Australia during the coronavirus disease 2019 ***:Data were extracted from publicly available datasets from Medicare Ben efits Schedule using item nu mbers assig ned to each comm only performed urological interve *** procedures were divided into three groups:Oncological therapeutic,diagnostic,and non-oncological therapeutic procedures.A smoothing model,based on the historic procedure numbers from 2017 to 2019,was used to forecast monthly number of procedures performed in each category between January 2020 and June *** forecasted models were compared with reported ***:A total of 108169 procedures were performed between January 2020 and June 2020 based on the Medicare Ben efits Schedule item nu mbers *** was a sign ifica nt reducti on(perce nt-age cha nge)in total procedures performed in April 2020(22.6%,95%con fide nee in terval[CI]:-28.7%to-15.4%)and May 2020(-33.2%,95%CI:-37.5%to 28.3%).There was a significant reduction in oncological therapeutic,non-oncological therapeutic,and diagnostic procedures performed in April 2020 and May 2020(p<0.05).These nu mbers did not in elude procedures performed in public ***:There was a significant reduction in total urological procedures(including diagnostic,oncological,and non-on cological)performed in mon ths of April 2020 and May 2020 during time of federal *** public and private healthcare sectors need to be supported in the up-comi ng mon ths to preve nt further delays in treatme nt and poorer clinical outcomes.

关键词： Coronavirus Urology Corona virus disease Elective procedures

Oral microbiota and host innate immune response in bisphosphonate-related osteonecrosis of the jaw

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International Journal of Oral Science 2014年第4期6卷 219-226页

作者： Smruti Pushalkar Xin Li Zoya Kurago lalitha V Ramanathapuram Satoko Matsumura Kenneth E Fleisher Robert Glickman Wenbo Yan Yihong Li Deepak Saxena Department of Basic Science and Craniofacial Biology New York University College of Dentistry Department of Oral and Maxillofacial Pathology Radiology and Medicine New York University College of Dentistry Department of Oral and Maxillofacial Surgery New York University College of Dentistry Department of Biology Nyack College

Bacterial biofilms have emerged as potential critical triggers in the pathogenesis of bisphosphonate（BP）-related osteonecrosis of the jaw（ONJ） or BRONJ. BRONJ lesions have shown to be heavily colonized by oral bacteria, most of these difficult to cultivate and presents many clinical challenges. The purpose of this study was to characterize the bacterial diversity in BRONJ lesions and to determine host immune response. We examined tissue specimens from three cohorts（n530）; patients with periodontal disease without a history of BP therapy（Control, n510）, patients with periodontal disease having history of BP therapy but without ONJ（BP, n55） and patients with BRONJ（BRONJ, n515）. Denaturing gradient gel electrophoresis of polymerase chain reaction（PCR）-amplified 16 S r RNA gene fragments revealed less bacterial diversity in BRONJ than BP and Control cohorts. Sequence analysis detected six phyla with predominant affiliation to Firmicutes in BRONJ（71.6%）, BP（70.3%） and Control（59.1%）. Significant differences（P,0.05） in genera were observed, between Control/BP, Control/BRONJ and BP/BRONJ cohorts. Enzyme-linked immunosorbent assay（ELISA）results indicated that the levels of myeloperoxidase were significantly lower, whereas interleukin-6 and tumor necrosis factor-alpha levels were moderately elevated in BRONJ patients as compared to Controls. PCR array showed significant changes in BRONJ patients with downregulation of host genes, such as nucleotide-binding oligomerization domain containing protein 2, and cathepsin G, the key modulators for antibacterial response and upregulation of secretory leukocyte protease inhibitor, proteinase 3 and conserved helix–loop–helix ubiquitous kinase. The results suggest that colonization of unique bacterial communities coupled with deficient innate immune response is likely to impact the pathogenesis of ONJ.

关键词： bisphosphonates denaturing gradient gel electrophoresis host response innate immunity oral microbiota osteonecrosis of the jaw

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水分对黑胡椒真菌生长的影响

世界热带农业信息 1987年第5期 52-54页

作者： V.P.sreedharan 陈里林

测定了不同相对湿度下适于黑胡椒真菌生长的含水量。黑胡椒含水量为18％时,就会生长真菌,但在次低的14.9％含水量时,没有发现真菌生长。显微检测表明,浸染新鲜胡椒的真菌有单端孢(Trichothecium)、刺盘孢(Colletetrichum)和镰孢霉(Fusar... 详细信息

测定了不同相对湿度下适于黑胡椒真菌生长的含水量。黑胡椒含水量为18％时,就会生长真菌,但在次低的14.9％含水量时,没有发现真菌生长。显微检测表明,浸染新鲜胡椒的真菌有单端孢(Trichothecium)、刺盘孢(Colletetrichum)和镰孢霉(Fusarium),侵染黑胡椒的有曲霉(Aspergilli)和青霉(Penicillium)。

关键词：含水量含水率黑胡椒真菌

Mapping of Aluminous Rich Laterite Depositions through Hyper Spectral Remote Sensing

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International Journal of Geosciences 2018年第2期9卷 93-105页

作者： M. J. Ratnakanth Babu E. N. Dhanamjaya Rao lalitha Kallempudi Das Iswar Chandra Department of Mines & Geology Government of Andhra Pradesh Vijayawada India Department of Geology Andhra University Visakhapatnam India Department of Geography Andhra University Visakhapatnam India National Remote Sensing Centre Hyderabad India

Increased dimensionality of the satellite data proves to be very useful for discriminating features with very close spectral matching. Present study concentrates on the retrieval of reflectance spectra from the level one radiometrically corrected data in Koraput district (Orissa) for the Bauxite ore. In the present study, atmospheric correction model FLAASH has been used to retrieve reflectance from the radiance data. Preprocessing of the dataset has been done before applying atmospheric correction on the dataset. Spectral subsetting of noise prone bands has been successfully done. Local destriping of the affected bands has been done using a 3*3 local mean filter. Spectral signatures of samples were derived from the processed data. Spectral signature of each sample and derived features vectors were correlated with the satellite image of the area and distribution of each feature was demarcated. Spatial abundance of each feature was used in preparation of mineral abundance map. Accuracy of the map was assessed using training sets of representative geological units. The mineral abundance mapping using the spectral analysis of the reflectance image involves the endmember collection using the N-Dimensional visualizer tool in ENVI software. Laterite, Bauxite, Iron and silica rich Aluminous laterite soil, Alluvium and Forest were selected as the end members after understanding the geology and analysis of the reflectance image. Various mapping techniques were applied to generate the final classified mineral abundance Map, Linear Spectral Unmixing, Mixture Tune Matched Filtering, Spectral Feature Fitting, Spectral Angle Mapper were the techniques used. Results have revealed the ability of Hyper spectral Remote sensing data for the identification and mapping of Hydrothermal altered products like Bauxite, Aluminous Laterite. This technology can be utilized for targeting minerals in the altered zone.

关键词： Hyperspectral Remote Sensing Aluminous Rich Laterite Imaging Spectroscopy Hydro Thermal Altered Ores

Effect of quercetin against lindane induced alterations in the serum and hepatic tissue lipids in wistar rats

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Asian Pacific Journal of Tropical Biomedicine 2012年第11期2卷 910-915页

作者： Viswanadha Vijaya Padma Gurusamy lalitha Nichokon Puthanveedu Shirony Rathinasamy Baskaran Animal tissue culture and Molecular genetics Laboratory Department of BiotechnologySchool of Biotechnology and Genetic EngineeringBharathiar University Department of Biotechnology PSG College of Arts and ScienceCoimbatoreTamilnaduIndia

Objective:To assess the effect of quercetin(flavonoid) against lindane induced alterations in lipid profile of wistar ***:Rats were administered orally with lindane(100 mg/kg body weight) and quercetin(10 mg/kg body weight) for 30 *** the end of treatment period lipid profile was estimated in serum and ***:Elevated levels of serum cholesterol, triglycerides,low density lipoprotein(LDL),very Low Density Lipoprotein(VLDL) and tissue triglycerides,cholesterol with concomitant decrease in serum HDL and tissue phospholipids were decreased in lindane treated rats were found to be significantly decreased in the quercetin and lindane co-treated ***:Our study suggests that quercetin has hypolipidemic effect and offers protection against lindane induced toxicity in liver by restoring the altered levels of *** quercetin cotreatment along with lindane for 30 days reversed these biochemical alterations in lipids induced by lindane.

关键词： Lindane Quercetin Oxidative stress Low density lipoprotein Very low density lipoprotein High density lipoprotein Triglycerides

Increased Prevalence of Severe Rheumatic Heart Disease Requiring Early Valve Replacement Surgery and Fragmented Germ Cells

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International Journal of Clinical Medicine 2014年第21期5卷 1392-1399页

作者： Elizabeth Jeya Vardhini Samuel Ramesh K. B. Latha K. V. lalitha Peter Prashanth Bosco Emmanuel Department of General Medicine Pondicherry Institute of Medical Sciences Pondicherry India Department of Pediatrics Pondicherry Institute of Medical Sciences Pondicherry India Central Electrochemical Research Institute (CECRI) Karaikudi India

Background: Patients requiring valve replacement at a younger age, for rheumatic heart disease was apparently increasing after the new age practice of contraception. Methods: In 2012, data of patients referred to tertiary care hospital from two cardiology screening camps conducted in the community, were analyzed for the severity of presentation of rheumatic heart disease and associated contraception status by dividing into the three age groups—20 - 35 years, 36 - 50 years, >51 years;~400 patients attended the camps;31 female and 2 male patients were referred to the tertiary care hospital for further evaluation and categorized treatment, including valve replacement surgeries;among the 33 referred patients, belonging to the three age groups, the data were analyzed for [if any] correlation of contraception status with severe rheumatic heart disease. 8 randomly chosen males, of the 3 age groups, from a different community, whose life partners had undergone sterilization, were assessed for their serum testosterone levels. Results: Among 20 - 35 years, 7 female patients with contraception required valve replacement surgeries [p 51 years, 3 female and 2 male patients without contraception received medical treatment only

关键词： Fragmented Germ Cells Reduced Endogenous Androgen Estrogen Deranged Cell Metabolism Defaulted Genomic Repertoire Enhanced Fibrosis

Versatility of microbial proteases

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Advances in Enzyme Research 2013年第3期1卷 39-51页

作者： Veloorvalappil N. Jisha Robinson B. Smitha Selvanesan Pradeep Sasidharan Sreedevi Kizhakkepawothail N. Unni sreedharan Sajith Prakasan Priji Moolakkariyil Sarath Josh Sailas Benjamin Enzyme Technology Laboratory Biotechnology Division Department of Botany University of Calicut Kerala India

Proteases or peptidases constitute the largest group of enzymes in bio-industry with a long array of uses. They play an invincible role in industrial biotechnology, especially in detergent, food and pharmaceutical arena. This focused review encompasses an overview on alkaline proteases, mainly of microbial sources in a handy module. Following an introduction and general classification with evolutionary insight, major sources of proteases (animal, plant and microbial including fungal, bacterial), their general properties with mechanism of action and molecular masses are discussed. Proteases fromBacillusspp. have been given special attention. In addition to this, an overview on the applications of proteases in detergent, tannery, food, metal recovery and waste treatment industries is also addressed briefly.

关键词： Review Proteases Classification Sources Bacillus Industrial Uses