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非等温长输管线稳态泄漏计算模型

天津大学学报 2005年第12期38卷 1115-1121页

作者：杨昭张甫仁赖建波天津大学机械工程学院天津300072

为了客观准确地计算燃气管道泄漏时的泄漏率、泄漏孔口内外温度和压力分布,通过对长输管线微元段燃气压缩因子、摩擦系数、泄漏系数、压力修正系数以及温度修正系数的分析讨论,结合现有泄漏模型,建立了非等温条件下的稳态管道泄漏小孔... 详细信息

为了客观准确地计算燃气管道泄漏时的泄漏率、泄漏孔口内外温度和压力分布,通过对长输管线微元段燃气压缩因子、摩擦系数、泄漏系数、压力修正系数以及温度修正系数的分析讨论,结合现有泄漏模型,建立了非等温条件下的稳态管道泄漏小孔、管道及大孔模型．对大孔模型泄漏过程,提出了综合三状态模式及具体两状态模式．通过对非等温条件下3种泄漏模型计算结果的比较,得出小孔模型适用于孔径比约为0．15的泄漏,管道模型适用于孔径比约为0．9的泄漏,而大孔模型在各种泄漏孔径下均比较适用,所得计算结果均合理可靠．

关键词：非等温长输管线泄漏稳态计算模型

Dopamine D2 receptors in the dorsomedial prefrontal cortex modulate social hierarchy in male mice

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Current Zoology 2023年第6期69卷 682-693页

作者： lai-fu Li Zi-Lin Li Bai-Lin Song Yi Jiang Yan Wang Hua-Wei Zou Lun-Guang Yao Ying-Juan Liu Henan Key Laboratory of Insect Biology in funiu Mountain Henan International Joint Laboratory of Insect BiologyCollege of Life Science and Agricultural EngineeringNanyang Normal UniversityNanyang 473061HenanChina Research Center of Henan Provincial Agricultural Biomass Resource Engineering and Technology College of Life Science and AgricultureNanyang Normal UniversityNanyang 473061HenanChina

Social hierarchy greatly influences behavior and *** human and animal studies have signaled the medial prefrontal cortex(mPFC)as specifically related to social *** D1 receptors(D1Rs)and D2 receptors(D2Rs)are abundantly expressed in the mPFC,modulat-ing its ***,it is unclear how DR-expressing neurons in the mPFC regulate social ***,using a confrontation tube test,we found that most adult C57BL/6J male mice could establish a linear social rank after 1 week of *** rank individuals showed social anxiety together with decreased serum testosterone levels.D2R expression was significantly downregulated in the dorsal part of mPFC(dmPFC)in lower rank individuals,whereas D1R expression showed no significant difference among the rank groups in the whole *** knockdown of D2Rs in the dmPFC led to mice being particularly prone to lose the contests in the confrontation tube ***,simultaneous D2R activation in the subordinates and D2R inhibition in the dominants in a pair switched their dominant-subordinate *** above results indicate that D2Rs in the dmPFC play an important role in social *** findings provide novel insights into the divergent func-tions of prefrontal D1Rs and D2Rs in social dominance,which may contribute to ameliorating social dysfunctions along with abnormal social hierarchy.

关键词： dopamine receptors medial prefrontal cortex social dominance social hierarchy tube test

A dynamic holographic modelling method of digital twin scenes for bridge construction

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International Journal of Digital Earth 2023年第1期16卷 2404-2425页

作者： Jianlin Wu Jun Zhu Jinbin Zhang Pei Dang Weilian Li Yukun Guo Lin fu Jianbo lai Jigang You YaKun Xie Ce Liang Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduPeople’s Republic of China Institute of Geodesy and Geoinformation University of BonnBonnGermany School of Engineering and Geomatics Southwest Petroleum UniversityChengduPeople’s Republic of China Institute of Computing Technology China Academy of Railway Sciences CoLtdBeijingPeople’s Republic of China

Holographic projection technology can provide a more intuitive and efficient visualization effect for a digital twin bridge construction ***,pre-rendering methods in the existing research work are usually used to implement holographic visualization,which is static *** above-mentioned methods for static display have many shortcomings,such as poor adaptability,low rendering efficiency and lack of real-time.A dynamic holographic modelling approach is proposed for the augmented visualization of digital twin scenes for bridge ***,a dynamic segmentation algorithm with adaptive screen size was designed to high-efficiently generate holographic ***,a motion blur control method was designed to improve the rendering efficiency of holographic scenes according to human visual ***,a prototype system was developed,and the corresponding experimental analysis was *** experimental results show that the method proposed in this article can support adaptive screen size image segmentation and real-time generation of holographic scenes for bridge *** amount of scene data can be reduced to more than 30%,which significantly improves rendering efficiency and reduces glare.

关键词： Bridge construction Digital twins Holographic scene Adaptive segmentation Rendering optimization

Pedunculated hepatocellular carcinoma and splenic metastasis

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World Journal of Gastroenterology 2009年第41期15卷 5239-5241页

作者： Mao-Lin Yan Yao-Dong Wang Zhi-De lai Yi-Feng Tian Hong-Biao Chen fu-Nan Qiu Song-Qiang Zhou Department of Hepatobiliary Surgery Fujian Provincial Hospital Fuzhou 350001 Fujian Province China

Only a few cases of pedunculated hepatocellular carcinoma (P-HCC) have been reported in the literature. The common sites of extrahepatic metastases in patients with HCC are the lungs, regional lymph nodes, kidney, bone marrow and adrenals. Metastasis to spleen is mostly via hematogenous metastasis, direct metastasis to spleen was very rare. We report a case of P-HCC presenting as a left upper abdominal lesions which involved the spleen that was actually a P-HCC with splenic metastasis. This case is unique as P-HCC directly involved the spleen which is not via hematogenous metastasis.

关键词： Pedunculated hepatocellular carcinoma Splenic metastasis Hematogenous metastasis Direct metastasis Splenectomy

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一种基于误差快速扩散元胞自动机的加密技术

物理学报 2011年第6期60卷 70-75页

作者：王福来浙江财经学院数学与统计学院杭州310012

构造了一个具有较大密钥空间的新型一维元胞自动机.在该元胞自动机中,密钥为采用移位映射的伪随机序列及受控扰动项,避免了数据膨胀,元胞自动机具有随机性触发规则.该元胞自动机一次处理信息量大,避免了复杂的计算过程.所生成的流密码... 详细信息

构造了一个具有较大密钥空间的新型一维元胞自动机.在该元胞自动机中,密钥为采用移位映射的伪随机序列及受控扰动项,避免了数据膨胀,元胞自动机具有随机性触发规则.该元胞自动机一次处理信息量大,避免了复杂的计算过程.所生成的流密码在理论上被证明了具有理想的随机性与雪崩效应,误差扩散速度快.实证分析研究表明,流密码不仅在全局上、而且在局部上都具有良好的随机性能,通过测试长度为24000的流密码在400次迭代产生的数据表明,经χ2检验,在显著性水平为5%时,频数检验通过率超过95%,序列检验通过率为100%;数据敏感性检验方面,密钥在任意位置改变1bit导致各流密码比特数发生改变的平均值(灵敏值为V)为49%—51%之间(理论上V=50%),均值为49.99%,方差为1.193×10-5.因此这是一个较理想的加密技术工具.

关键词：保密通信元胞自动机伪随机序列

Animal models of tendon calcification:Past,present,and future

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Animal Models and Experimental Medicine 2024年第4期7卷 471-483页

作者： Ruichen Li Canhao lai Hong Luo Yujian Lan Xinfang Duan Dingsu Bao Zhipeng Hou Huan Liu Shijie fu Department of Bone and Joint The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhouChina Chengdu University of Traditional Chinese Medicine ChengduChina

Tendon calcification is a common clinical condition that frequently occurs as a complication after tendon injury and surgery,or as an expression of fibrodysplasia ossificans *** condition can be referred to by various names in clinical practice and literature,including tendon ossification,tendon mineralization,heterotopic ossification,and calcific *** exact pathogenesis of tendon calcification remains uncertain,but current mainstream research suggests that calcification is mostly cell *** further elucidate the pathogenesis of tendon calcification and to better simulate the overall process,selecting appropriate experimental animal models is *** animal models have been utilized in various clinical studies,each with its own set of advantages and *** this review,we have discussed the advancements made in research on animal models of tendon calcification,with a focus on the selection of experimental animals,the sites of injury in these models,and the methods employed for modeling.

关键词： animal models review tendon calcification

functional dissection of parabrachial substrates in processing nociceptive information

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Zoological Research 2024年第3期45卷 633-647页

作者： Jin Ke Wei-Cheng Lu Hai-yang Jing Shen Qian Sun-Wook Moon Guang-fu Cui Wei-Xin Qian Xiao-Jing Che Qian Zhang Shi-Shi lai Ling Zhang Ying-Jie Zhu Jing-Dun Xie Tian-Wen Huang Shenzhen Key Laboratory of Drug Addiction Shenzhen-Hong Kong Institute of Brain ScienceBrain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China University of Chinese Academy of Sciences Beijing 100049China Department of Anesthesiology State Key Laboratory of Oncology in South ChinaGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhouGuangdong 510060China University of Science and Technology of China HefeiAnhui 230027China Department of Anesthesiology Shenzhen University General Hospital and Shenzhen University Academy of Clinical Medical SciencesShenzhen UniversityShenzhenGuangdong 518055China School of Medicine Yunnan UniversityKunmingYunnan 650091China

Painful stimuli elicit first-line reflexive defensive reactions and,in many cases,also evoke second-line recuperative behaviors,the latter of which reflects the sensing of tissue damage and the alleviation of *** lateral parabrachial nucleus(lPBN),composed of external-(elPBN),dorsal-(dlPBN),and central/superior-subnuclei(jointly referred to as slPBN),receives sensory inputs from spinal projection neurons and plays important roles in processing affective information from external threats and body integrity ***,the organizational rules of lPBN neurons that provoke diverse behaviors in response to different painful stimuli from cutaneous and deep tissues remain *** this study,we used region-specific neuronal depletion or silencing approaches combined with a battery of behavioral assays to show that slPBN neurons expressing substance P receptor(NK1R)(lPBNNK1R)are crucial for driving pain-associated self-care behaviors evoked by sustained noxious thermal and mechanical stimuli applied to skin or bone/muscle,while elPBN neurons are dispensable for driving such ***,lPBNNK1R neurons are specifically required for forming sustained somatic pain-induced negative teaching signals and aversive memory but are not necessary for fear-learning or escape behaviors elicited by external ***,both lPBNNK1R and elPBN neurons contribute to chemical irritant-induced nocifensive *** results reveal the functional organization of parabrachial substrates that drive distinct behavioral outcomes in response to sustained pain versus external danger under physiological conditions.

关键词： Lateral parabrachial nucleus Substance P receptor Pain affect Defensive reaction Somatosensory

The effect of sensation of transmission along meridian acupuncture for chronic nonbacterial prostatitis

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World Journal of Acupuncture-Moxibustion 2019年第2期29卷 113-118页

作者： Shu-ren MING Yu-lin fu Wen-guang HOU Yue-lai CHEN Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai 200437 China

Objective:To investigate the short-term efficacy difference between sensation of transmission along meridian acupuncture and non-sensation of transmission along meridian acupuncture in the treatment of chronic nonbacterial ***:A randomized,controlled,and single-blind clinical study was performed to collect 63 patients with chronic nonbacterial prostatitis who met the inclusion criteria and were randomly assigned to a transmission sensation group(31 patients)and a non-transmission sensation group(32 patients).The two groups of patients took the same acupuncture *** they were lying down on their backs,Guānyuán(关元 CV4),Zhōngjí(中极 CV3)and Dàhè(大赫 K112)were *** they were lying down on their stomachs,Shènshū(肾俞 BL 23),Cìliáo(次髎 BL32)and Huìyáng(会阳 BL35)were *** them,the transmission sensation group was treated with transmission sensation along meridian to apply deep needling to the lower abdomen and lumbosacral acupuncture points with lifting,thrusting,and twirling method,so that the needling sensation was transmitted to the bladder,perineum and *** non-transmission sensation group was treated with non-transmission sensation along meridian,and the acupuncture points were treated with conventional acupuncture until the patient felt soreness and distending *** the arrival of *** groups of patients were treated with electro-acupuncture during acupuncture,and the sparse-dense wave(sparse wave 4 Hz,dense wave 20 Hz),and the needle retention continued for 20 *** patients were treated for 3 times with once every other day,and the treatment lasted for one *** CV4,CV3 and KI12 were used in the first and third treatments,and the BL23,BL32 and BL35 were used in the second *** National Institute of Health chronic prostatitis syndrome index(NIH-CPSI)and Hamilton Anxiety Rating Scale(HAMA)were observed,and the clinical efficacies of the patient were ***:After treatment,the NIH-CPSI scores(18.29±1.25,

关键词： Acupuncture Transmission sensation along meridian Chronic nonbacterial prostatitis

Cryogenic Photodetachment Spectroscopy and High-Resolution Resonant Photoelectron Imaging of Cold para-Ethylphenolate Anions

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Precision Chemistry 2023年第3期1卷 161-174页

作者： Dao-fu Yuan Yue-Rou Zhang Chen-Hui Qian Guo-Zhu Zhu lai-Sheng Wang Department of Chemistry Brown UniversityProvidenceRhode Island 02912United States

Valence-bound molecular anions with polar neutral cores(μ>2.5 D)can support highly diffuse dipole-bound states(DBSs)as electronically excited states just below the detachment *** weakly bound nonvalence excited states have little influence on the structure of the neutral core,and they usually have the same vibrational *** can be systematically searched using photodetachment spectroscopy(PDS),which can yield the binding energies of the DBSs,the electron detachment threshold of the anion,and above-threshold vibrational levels of the DBSs(Feshbach resonances).We have shown that the combination of PDS and resonant photoelectron spectroscopy(rPES)at the Feshbach resonances is a powerful approach to obtain rich vibrational information for complex molecular radicals.A prerequisite for this technique is to produce vibrationally cold anions,made possible by a cryogenically controlled Paul *** this article,we report a PDS and rPES study of cold para-ethylphenolate anions(p-EP^(-)).The electron affinity of the p-EP radical is measured to be 17425±3 cm^(-1)(2.1604±0.0004 eV),and a DBS is found at 145 cm^(-1) below the detachment threshold of p-EP^(-).Thirty-four vibrational levels are observed for the DBS,including two bound levels and 32 Feshbach *** for 17 vibrational modes of the p-EP radical are measured from the combination of PDS and rPES,including six symmetry-forbidden modes with A″*** current study confirms again the power of combining cryogenic ion cooling with PDS and highresolution rPES to obtain spectroscopic information on complex molecular radicals.

关键词： dipole-bound state photoelectron imaging cryogenic ion cooling resonant photoelectron spectroscopy ethylphenoxy radical vibrational frequencies electrospray ionization