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High-rate and high-capacity measurement-deviceindependent quantum key distribution with Fibonacci matrix coding in free space

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Science China(Information Sciences) 2018年第6期61卷 227-237页

作者： Hong lai Mingxing LUO Josef PIEPRZYK Jun ZHANG Lei PAN Mehmet A.ORGUN School of Computer and Information Science and Centre for Research and Innovation in Software Engineering (RISE) Southwest University Information Security and National Computing Grid Laboratory School of Information Science and TechnologySouthwest Jiaotong University School of Electrical Engineering and Computer Science Queensland University of Technology Institute of Computer Science Polish Academy of Sciences School of Information Technology Deakin University Department of Computing Macquarie University Faculty of Information Technology Macau University of Science and Technology

This paper proposes a high-rate and high-capacity measurement-device-independent quantum key distribution(MDI-QKD) protocol with Fibonacci-valued and Lucas-valued orbital angular momentum(OAM) entangled states in free space. In the existing MDI-OAM-QKD protocols, the main encoding algorithm handles encoded numbers in a bit-by-bit manner. To design a fast encoding algorithm, we introduce a Fibonacci matrix coding algorithm, by which, encoded numbers are separated into segments longer than one bit. By doing so, when compared to the existing MDI-OAM-QKD protocols, the new protocol can effectively increase the key rate and the coding capacity. This is because Fibonacci sequences are used in preparing OAM entangled states, reducing the misattribution errors(which slow down the execution cycle of the entire QKD) in QKD protocols. Moreover, our protocol keeps the data blocks as small as possible, so as to have more blocks in a given time interval. Most importantly, our proposed protocol can distill multiple Fibonacci key matrices from the same block of data, thus reducing the statistical fluctuations in the sample and increasing the final QKD rate. Last but not the least, the sender and the receiver can omit classical information exchange and bit flipping in the secure key distillation stage.

关键词： measurement-device-independent quantum key distribution Fibonacci-matrix coding free space orbital angular momentum bit flipping misattribution errors

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Classification of iatrogenic bile duct injury

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Hepatobiliary & Pancreatic Diseases International 2007年第5期6卷 459-463页

作者： Wan-Yee Lau Eric C.H.lai Department of Surgery the Chinese University of Hong KongShatinNew TerritoriesHong Kong SARChina

BACKGROUND: Iatrogenic bile duct injury continues to be an important clinical problem, resulting in serious morbidity, and occasional mortality, to patients. The ease of management, operative risk, and outcome of bile duct injuries vary considerably, and are highly dependent on the type of injury and its location. This article reviews the various classification systems of bile duct injury. DATA SOURCES: A Medline, PubMed database search was performed to identify relevant articles using the keywords 'bile duct injury', 'cholecystectomy', and 'classification'. Additional papers were identified by a manual search of the references from the key articles. RESULTS: Traditionally, biliary injuries have been classified using the Bismuth's classification. This classification, which originated from the era of open surgery, is intended to help the surgeons to choose the appropriate technique for the repair, and it has a good correlation with the final outcome after surgical repair. However, the Bismuth's classification does not encompass the whole spectrum of injuries that are possible. Bile duct injury during laparoscopic cholecystectomy tends to be more severe than those with open cholecystectomy. Strasberg's classification made Bismuth's classification much more comprehensive by including various other types of extrahepatic bile duct injuries. Our group, Bergman et al, Neuhaus et al, Csendes et al, and Stewart et al have also proposed other classification systems to complement the Bismuth's classification. CONCLUSIONS: None of the classification system is universally accepted as each has its own limitation. Hopefully, a universally accepted comprehensive classification system will be published in the near future.

关键词： laparoscopic cholecystectomy bile duct injury bile duct stricture bile leak classification

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川西九龙打枪沟锂铍矿石特征及其铷元素赋存状态和分布规律研究

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矿产综合利用 2022年第5期43卷 186-193页

作者：赖杨邓伟中国地质科学院矿产综合利用研究所四川成都610041

打枪沟锂铍矿位于四川省甘孜州九龙县乃渠乡新山沟-打枪沟一带,矿体产于石英闪长岩体节理中及三叠系新都桥组黑云石英片岩节理中。矿石中主要矿物为碱性长石、钠长石、石英,含量分别为31.35%、23.75%、30.33%;次要矿物为白云母和锂辉石... 详细信息

打枪沟锂铍矿位于四川省甘孜州九龙县乃渠乡新山沟-打枪沟一带,矿体产于石英闪长岩体节理中及三叠系新都桥组黑云石英片岩节理中。矿石中主要矿物为碱性长石、钠长石、石英,含量分别为31.35%、23.75%、30.33%;次要矿物为白云母和锂辉石,含量分别为8.44%、5.17%;另含少量黏土矿物、磷灰石等矿物。矿石中Li_(2)O品位0.44%,BeO品位为0.082%,伴生Rb_(2)O的品位为0.20%。本文通过矿石光薄片镜下鉴定、化学分析、电子探针分析以及AMICS矿物自动分析等测试手段,开展打枪沟锂铍矿矿石特征研究,并查明矿石中稀有金属铷元素的赋存状态及分布规律,为今后矿床的勘探、开发以及矿产资源综合利用提供基础参考资料。

关键词：铷元素赋存状态分布规律锂铍矿打枪沟

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Effect of normalization on texture evolution of 0.2-mm-thick thingauge non-oriented electrical steels with strong η-fiber textures

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Journal of Iron and Steel Research International 2019年第11期26卷 1219-1227页

作者： Jing Qin De-fu Liu Ye Yue Hong-jin Zhao Chao-bin lai School of Materials Science and Engineering Jiangxi University of Science and TechnologyGanzhou 341000JiangxiChina School of Metallurgy and Chemical Engineering Jiangxi University of Science and TechnologyGanzhou 341000JiangxiChina

Thin-gauge non-oriented electrical steel sheets of 0.2 mm in thickness with high magnetic induction and low core loss were produced by a two-stage cold-rolling method with and without normalization *** through-process texture evolutions of the two processes were compared and studied by means of X-ray diffractometer and electron backscattered *** showed that excellent magnetic properties were attributed to strong η-fiber recrystallization texture in the final *** γ-fiber-oriented grains after intermediate annealing and medium cold-rolling reduction were considered key factors to obtain a strong γ-fiber texture given that a large number of shear bands within the γ-fiber deformed matrix provided dominant nucleation sites for η-fiber-oriented *** normalization annealing after hot rolling was favorable for the retention of cube texture,thereby decreasing the magnetic anisotropy of thin-gauge non-oriented electrical steels.

关键词： Thin-gauge non-oriented electrical steel Two-stage cold-rolling method Microstructure Texture evolution Magnetic property

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可修复备件系统库存决策仿真优化模型

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系统工程与电子技术 2009年第6期31卷 1510-1514页

作者：张衡花兴来许绍杰空军雷达学院预警探测装备系湖北武汉430019

针对可修复备件系统库存决策问题,在考虑系统成本和保障率的前提下,建立一个仿真优化集成模型。该模型分析了可修复备件系统结构和流程,应用离散系统仿真技术实现了可修复备件库存的仿真,并以禁忌搜索算法为基础建立优化仿真框架,对备... 详细信息

针对可修复备件系统库存决策问题,在考虑系统成本和保障率的前提下,建立一个仿真优化集成模型。该模型分析了可修复备件系统结构和流程,应用离散系统仿真技术实现了可修复备件库存的仿真,并以禁忌搜索算法为基础建立优化仿真框架,对备件库存数量的最优解进行仿真寻优计算。优化仿真结果表明,该模型合理、有效、可行。

关键词：可修复备件库存决策仿真优化模型禁忌搜索

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Effect of Pressure-Controlled Inverse Ratio Ventilation on WBC,PCT and CRP in Rats Undergoing Radical Gastrectomy and Related Mechanism

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Chinese Journal of Biomedical Engineering(English Edition) 2023年第1期32卷 11-18页

作者： LI Chun-yang PENG Xiao-hui WAN Hui-lai Zheng Yue The Fifth Hospital of Xiamen Xiamen Fujian 361101China

Objective:To explore the effect of pressure-controlled inverse ratio ventilation on partial pressure of oxygen(PaO_(2)),partial pressure of carbon dioxide(PaC O2),dynamic lung compliance(Cdyn),white blood cell(WBC),procalcitonin(PCT),C-reactive protein(CRP),and other ***:A total of 100 healthy Wistar rats,aged 6-8 weeks and weighing 300-356 g,were used to establish gastric cancer models with 1-methyl-3-nitro-1-nitrosoguanidine(MNNG).60 gastric cancer rats were randomly divided into three groups and treated with laparoscopic radical gastrectomy after *** in the VCV group were given volume control ventilation,rats in the PCV group were given pressure control ventilation,and rats in the PC-IRV group were given pressure control inverse ratio *** levels of WBC,PCT and CRP in the three groups were observed and compared on the 1st,3rd and 5th day after ***:There were significant differences in PaO_(2)levels at 15 min after ventilation mode change and at the time of pneumoperitoneum closure,and in PaCO_(2)and Cdyn levels at 10 min after induction and at 15 min after ventilation mode change among the three groups(P<0.05).The PaO_(2)levels in PC-IRV group were higher than those in VCV group and PCV group at 15 min after the ventilation mode was changed and at the time of closing the *** level of PaCO_(2)in PC-IRV group was lower than that in VCV group and PCV group 10 min after induction and 15 min after ventilation mode change,and the level of PaCO_(2)in PC-IRV group was lower than that in VCV group when pneumoperitoneum was turned *** level of Cdyn in PC-IRV group was higher than that in VCV group and PCV group at 10 min after induction and 15 min after ventilation mode *** level of Cdyn in PC-IRV group was higher than that in PCV group at the time of closing *** Cdyn level in PCV group was lower than that in VCV group at 15 min after ventilation mode *** were signific

关键词： radical gastrectomy pressure-controlled inverse ratio ventilation(PC-IRV) rat experiment inflammatory index

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S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung

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Acta Pharmaceutica Sinica B 2023年第3期13卷 1110-1127页

作者： Mengyao Hao Rong Fu Jun Tai Zhenhuan Tian Xia Yuan Yang Chen Mingjin Wang Huimin Jiang Ming Ji Fangfang lai Nina Xue Liping Bai Yizhun Zhu Xiaoxi Lv Xiaoguang Chen Jing Jin State Key Laboratory of Bioactive Substances and Functions of Natural Medicines Institute of Materia MedicaChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100050China Department of Otolaryngology Head and Neck SurgeryChildren's Hospital Capital Institute of PediatricsBeijing 100020China Department of Thoracic Surgery Peking Union Medical College HospitalPeking Union Medical CollegeDong Cheng DistrictBeijing 100730China State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Department of Pharmacology School of PharmaceuticalGuangzhou University of Chinese MedicineGuangzhou 510000China State Key Laboratory of Quality Research in Chinese Medicine Macao Institute for Applied Research in Medicine and HealthMacao University of Science and TechnologyTaipaMacao SAR 999078China

Idiopathic pulmonary fibrosis(IPF)is a progressive lung disease with unclear etiology and limited treatment *** median survival time for IPF patients is approximately 2–3 years and there is no effective intervention to treat IPF other than lung *** important components of lung tissue,endothelial cells(ECs)are associated with pulmonary ***,the role of endothelial dysfunction in pulmonary fibrosis(PF)is incompletely ***-1-phosphate receptor 1(S1PR1)is a G protein-coupled receptor highly expressed in lung *** expression is markedly reduced in patients with ***,we generated an endothelial-conditional S1pr1 knockout mouse model which exhibited inflammation and fibrosis with or without bleomycin(BLM)*** activation of S1PR1 with an S1PR1 agonist,IMMH002,exerted a potent therapeutic effect in mice with bleomycin-induced fibrosis by protecting the integrity of the endothelial *** results suggest that S1PR1 might be a promising drug target for IPF therapy.

关键词： Idiopathic pulmonary fibrosis Endothelial barrier Tight junction Sphingosine-1-phosphate receptor 1 Sphingosine-1-phosphate receptor 1 agonist FTY720 IMMH002 Protein stability

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Adult-born neurons in critical period maintain hippocampal seizures via local aberrant excitatory circuits

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Signal Transduction and Targeted Therapy 2023年第7期8卷 3427-3442页

作者： Liying Chen Yingwei Xu Heming Cheng Zhongxia Li Nanxi lai Menghan Li Yeping Ruan Yang Zheng Fan Fei Cenglin Xu Jiao Ma Shuang Wang Yan Gu Feng Han Zhong Chen Yi Wang Institute of Pharmacology&Toxicology College of Pharmaceutical SciencesSchool of MedicineZhejiang UniversityHangzhouChina Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhouChina Zhejiang Rehabilitation Medical Center Department The Third Affiliated HospitalZhejiang Chinese Medical UniversityHangzhouChina Key Laboratory of Cardiovascular&Cerebrovascular Medicine Drug Target and Drug Discovery CenterSchool of PharmacyNanjing Medical UniversityNanjingChina

Temporal lobe epilepsy(TLE),one common type of medically refractory epilepsy,is accompanied with altered adult-born dentate granule cells(abDGCs).However,the causal role of abDGCs in recurrent seizures of TLE is not fully ***,taking advantage of optogenetic and chemogenetic tools to selectively manipulate abDGCs in a reversible manner.

关键词： epilepsy seizures maintain

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Hepatocellular carcinoma: current management and recent advances

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Hepatobiliary & Pancreatic Diseases International 2008年第3期7卷 237-257页

作者： Wan-Yee Lau Eric C. H. lai Faculty of Medicine The Chinese University of Hong Kong Prince of Wales Hospital Shatin New Territories Hong Kong SAR China

BACKGROUND: Hepatocellular carcinoma (HCC) is a major health problem worldwide. It is the fifth most common cancer in the world, and the third most common cause of cancer-related death. Without specific treatment, the prognosis is very poor. The goal of management is 'cancer control'-a reduction in its incidence and mortality as well as an improvement in the quality of life of patients with HCC and their families. This article aims to review the current management of HCC and its recent advances. DATA SOURCES: A MEDLINE database search was performed to identify relevant article using the keywords 'hepatocellular carcinoma', 'hepatectomy', 'liver transplantation', and 'local ablative therapy'. Additional papers and book chapters were identified by a manual search of the references from the key articles. RESULTS: Liver resection and liver transplantation remain the options that give the best chance of a cure. Recent evidence suggests that local ablative therapy may offer comparable survival results in patients with small HCC, and preserved liver function. Transarterial chemoembolization (TACE) is the most promising palliative modality for unresectable HCC, but other techniques, such as transarterial radioembolization (TARE), and local ablative therapy, have also shown comparable results. CONCLUSIONS: Early diagnosis of HCC remains a key goal in improving the prognosis of patients. During the last two decades, operative mortality and surgical outcome of liver resection and liver transplantation for HCC have improved. Progress also has been made in multi-modality therapy which can increase the chance of survival and improve the quality of life for patients with advanced HCC.

关键词： hepatocellular carcinoma hepatectomy liver transplantation local ablative therapy

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Pyridinium tribromide catalyzed condensation of indoles and aldehydes to form bisindolylalkanes

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Chinese Chemical Letters 2011年第5期22卷 515-518页

作者： Qin Yang Zheng Lan Yin Ban lai Ouyang YiYuan Peng Key Laboratory of Green Chemistry Jiangxi Province and College of Chemistry Jiangxi Normal University Nanchang 330022 China Key Laboratory of Small Fuctional Organic Molecule Ministry of Education and College of Life Science Jiangxi Normal UniversityNanchang 330022 China

An efficient synthetic method for bis（indol-3-yl）alkane derivatives has been *** the presence of 5 mol%of pyridinium tribromide（PTB）,the condensation of indoles and aldehydes proceeded smoothly under mild conditio... 详细信息

关键词： Pyridinium tribromide Indole Aldehyde Bis(indol-3-yl)alkane

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