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物探化探译丛 1993年第A7期 103-105页

作者： lafe.,tr 孟令顺

Towards a New Model of Teacher training in Europe

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Journalism and Mass Communication 2024年第4期14卷 260-266页

作者： Teodor Pătrăuță “Vasile Goldiș”Western University of Arad AradRoumania

The current situation of European educational systems leads to the lack of historical precedents,considering that it implies the end of educational systems based on exclusion,configuring a new conception of educational systems that we are still not able to appreciate at their true value,because we were educated by and in the previous educational *** other references,we inevitably tend to compare current problems with previous situations,without understanding that the generalization of education to 100%of the population implies a qualitative change that modifies the objectives,forms of work,and the very essence of the educational *** stage change,marked by the acceleration of social changes,including the pandemic situation,explains why,despite the best educational system so far,teachers with the best levels of training and a financial and material endowment unimaginable until recently,try a sense of crisis and a general feeling of confusion is manifested among the teachers and parents of the children,seeing that education is no longer what it used to be(Esteve,1998).The key to defuse this apparent paradox is in the tendency to judge the new education system by the mentality and standards of the former selective education,in which most of the adults present were ***,although we continue to apply to the new general education situation the parameters of the previous situation,in which the selective system excluded every year the students who had behavior problems in the class or had difficulties regarding the mastery of certain educational subjects(Esteve,1998).In this way,we are currently criticizing the school failure of a percentage of our students,without realizing that their schooling itself is a success,because,although their level is low,they had no level *** speaks of a low educational level,when,in reality,the educational level is increasing—the general level of the people and the individual level of the best students(Baudelo

关键词： education model teacher education exclusion selection schooling

Challenges of Vietnamese Agricultural Cooperatives in the 21st Century:The Link Between Efficiency and Legality

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Economics World 2024年第1期11卷 42-53页

作者： trịnh Minh trạch tra Vinh University Tra VinhVietnam

The article shows that the situation of agricultural cooperatives in the world in general and agricultural cooperatives in Vietnam in particular are facing certain challenges in the context of globalization in the 21st *** article points out limitations on:the nature,principles of democratic member control and principles of surplus distribution of the International Cooperative Alliance,as well as Vietnamese law in cooperative management.

关键词： agricultural cooperative democratic principles principles of surplus distribution cooperative law

Granulometric and Mineralogical Characterization of the Sands of the Middle Course of the Kasai River (Territory of Ilebo, Province of Kasai/DR Congo)

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Journal of Geoscience and Environment Protection 2024年第7期12卷 50-71页

作者： Lowny trésor Madienga Kitshabi Ivon Ndala Tshiwisa Modeste Kisangala Muke Thomas Kanika Mamena Dominique Wetshondo Osomba Emmanuel Cibambula Musau Adalbert-Jules Makutu Ma Ngwayaya Department of Petroleum Exploration and Production Faculty of Oil Gas and Renewable Energies University of Kinshasa Kinshasa Democratic Republic of the Congo Department of Geosciences Faculty of Sciences and Technologies University of Kinshasa Kinshasa Democratic Republic of the Congo

The sand bars, in perpetual transformation, observable in the middle course of the Kasai river on the section between the city of Ilebo (pk605) to the confluence of the Loange river (pk525), pose enormous navigability problems. This may be dependent on hydrosedimentological characteristics of the Kasai River. This abundance of sand thus conditions the morphology of the middle course of the Kasai River in the section under our study. It therefore constitutes sedimentary navigation obstacles. The objective of this study is the granulometric and mineralogical characterization of the bar sands of the Kasai River in this study section. Particle size analyzes reveal these are moderately well classified to well classified unimodal sands (Classification coefficient between 1.29 to 1.742) largely presenting grain size symmetry and rarely fine asymmetry (Asymmetry coefficient—Skewness between −0.197 to 0.069) with mesorkurtic and rarely leptokurtic and platykurtic acuity (Angulosity coefficient—Kurtosis between 0.814 to 1.323). All these parameters evolve in sawtooth patterns from upstream to downstream. And then, an automated mineralogical analysis of the sands of the Kasaï River using a Qemscan FEG Quanta 650 made it possible to determine a very varied mineralogical procession with a sawtooth evolution. It is largely dominated by quartz (between 93.73% and 99.07%), followed by calcite (0.01% - 2.66%), iron oxides (0.01% - 1.88%), orthoclase (0.04% - 0.99%), plagioclase (0.01% - 0.75%) and Kaolinite (0.18% - 0.71%). Finally, this mineralogical procession is characterized by a group of minerals which do not reach the threshold of 0.55% such as: illite, apatite, ilmenite, muscovite, chlorite, biotite, montmorillonite, rutile, pyrophyllite, siderite, zircon and dolomite. The evolution of the mineralogical procession of the sands of the bars is not as clear as in the case of particle size parameters.

关键词： Characterization Granulometric Mineralogical Sands Middle Course Kasai River

Detailed Analysis of the Flow in the Inducer of a transonic Centrifugal Compressor

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Journal of Thermal Science 2012年第1期21卷 1-12页

作者： Nicolas Buffaz Isabelle trébinjac Laboratoire de Mécanique des Fluides et d'Acoustique Ecole Centrale de Lyon 36 av. Guy de Collongue

Numerical and experimental investigations were conducted in a transonic centrifugal compressor stage composed of a backswept splittered unshrouded impeller and a vaned diffuser. A detailed analysis of the flow in the inducer (i.e. the entry zone of the impeller between the main blade leading edge and the splitter blade leading edge) is proposed from choke to surge. Steady and unsteady simulations were performed using the code elsA, which uses a multi-domain approach on structured meshes and solves the compressible RANS equations, associated with a two-equation turbulence model k-l in the rotating frame of reference. The 1MW LMFA-ECL test rig was used for carrying out the tests in the compressor stage. Unsteady pressure measurements up to 150 kHz and Laser Doppler Anemometry measurements were performed in the inducer. A good agreement is obtained between the experimental and numerical data even if an over dissipation is noticed in the numerical results. The change in flow pattern from choke to surge is mainly due to a change in the tip leakage flow trajectory which straightens, leading to a flow blockage of an individual passage near shroud. A spectral analysis shows that only the blade passing frequency and its harmonics compose the various spectra obtained from choke to surge.

关键词： transonic centrifugal compressor inducer unsteady pressure measurements

Combined Oxidative Phosphorylation Deficiency-20-Exome as a Diagnostic Implement

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Journal of Biosciences and Medicines 2024年第6期12卷 7-12页

作者： Paulo Roberto Matos-Neto Lucas Antonissen Lima Verde Airton Ferreira da Ponte-Filho Luís Eduardo Oliveira Matos Amandha Espavier trés Paulo Roberto Lacerda Leal Gerardo Cristino-Filho Regina Coeli de Carvalho Porto Carneiro Faculty of Medicine Federal University of Cear Sobral Cear Brazil Department of Neurosurgery Federal University of Cear Sobral Cear Brazil Department of Neuropediatrics Federal University of Cear Sobral Cear Brazil

Mitochondrial disorders are phenotypically varied, with serious clinical repercussions. Among them, there is the deficiency of combined oxidative phosphorylation of type 20, which occurs due to a defect in the VARS2 gene. This article presents a case of a 2-year-old female with progressive myoclonic epilepsy and psychomotor regression, with refractoriness to multiple anticonvulsants. The diagnosis was only made after the examination was carried out. Therefore, this article highlights the aspects of this rare disease and the importance of the exome for the diagnosis of rare conditions.

关键词： Oxidative Phosphorylation Epilepsy Exome Mitochondrial Defect VARS2

Impeller-diffuser interaction:analysis of the unsteady flow structures based on their direction of propagation

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Journal of Thermal Science 2007年第3期16卷 193-202页

作者： N.Bulot I.trébinjac Ecole

The present study is focused on the analysis of the deterministic fluctuations arising from the rotor-stator interaction within a transonic centrifugal compressor stage. A spectral analysis applied to the unsteady flow field leads to the values of the rotation speed of most energetic modes. From these values, the various structures are classified according to their direction of propagation which leads to a comprehensive description of the underlying mechanisms involved in the interaction.

关键词： centrifugal compressor transonic flow rotor-stator interaction unsteady flow

Experimental Analysis of the Rotor Stator Interaction Within a High Pressure Centrifugal Compressor

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Journal of Thermal Science 2002年第1期11卷 1-9页

作者： Isabelle trébinjac Christophe Vixège Laboratoire de Mécanique des Fluides et d’Acoustique Ecole Centrale de Lyon Ecully Cedex France

An analysis of the experimental results obtained by laser two focus anemometry in the rotor-stator inter-row region of a high-speed high-pressure centrifugal compressor is presented with the aim of quantifying the unsteady effects of the rotor-stator interaction. Two complementary methods are used. First, the results are analyzed in terms of the time-averaging procedure developed by Adamczyk. The purely time dependent correlations of the velocity components are quantified. They show that the unsteady interaction is mainly due to the splitter wake-vane interaction. Then, it is shown that the rotor-stator interaction produces spatial harmonics which are identified as spinning modes by means of Fourier series.

关键词： rotor-stator interaction centrifugal compressor spectral analysis.

Digestive and breast cancer patients managed during the first wave of COVID-19 pandemic:Short and middle term outcomes

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World Journal of Methodology 2024年第2期14卷 107-126页

作者： Jacobo trébol Ana Carabias-Orgaz María Carmen Esteban-Velasco Asunción García-Plaza Juan Ignacio González-Munoz Ana Belén Sánchez-Casado Felipe Carlos Parreno-Manchado Marta Eguía-Larrea José Antonio Alcázar-Montero Cirugía General y del Aparato Digestivo Complejo Asistencial Universitario de SalamancaSalamanca 37007SalamancaSpain Cirugía Universidad de SalamancaSalamanca 37007SalamancaSpain Oftalmología Complejo Asistencial Universitario de SalamancaSalamanca 37007SalamancaSpain

BACKGROUND The first wave of coronavirus disease 2019(COVID-19)pandemic in Spain lasted from middle March to the end of June *** population was subjected to lockdown periods and scheduled surgeries were discontinued or reduced during variable *** our centre,we managed patients previously and newly diagnosed with *** established a strategy based on limiting perioperative social contacts,preoperative screening(symptoms and reverse transcriptionpolymerase chain reaction)and creating separated in-hospital COVID-19-free pathways for non-infected *** also adopted some practice modifications(surgery in different facilities,changes in staff and guidelines,using continuously changing personal protective equipment…),that supposed new *** To analyse cancer patients with a decision for surgery managed during the first wave,focalizing on outcomes and pandemic-related *** We prospectively included adults with a confirmed diagnosis of colorectal,oesophago-gastric,liver-pancreatic or breast cancer with a decision for surgery,regardless of whether they ultimately underwent *** analysed short-term outcomes[30-d postoperative morbimortality and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection]and outcomes after 3 years(adjuvant therapies,oncological events,death,SARS-CoV-2 infection and vaccination).We also investigated modifications to usual *** From 96 included patients,seven didn’t receive treatment that period and four never(3 due to COVID-19).Operated patients:28 colon and 21 rectal cancers;laparoscopy 53.6%/90.0%,mortality 3.57%/0%,major complications 7.04%/25.00%,anastomotic leaks 0%/5.00%,3-years disease-free survival(DFS)82.14%/52.4%and overall survival(OS)78.57%/76.2%.Six liver metastases and six pancreatic cancers:no mortality,one major complication,three grade A/B liver failures,one bile leak;3-year DFS 0%/33.3%and OS 50.0%/33.3%(liver metastases/pancreatic carcinoma).5 g

关键词： COVID-19 SARS-CoV-2 Colon cancer Rectal cancer Breast cancer Liver cancer Pancreatic cancer Gastric cancer Oesophageal cancer Surgery

Role of human epidermal growth factor receptor 2 in gastric cancer:Biological and pharmacological aspects

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World Journal of Gastroenterology 2014年第16期20卷 4526-4535页

作者： Jan tr?st J?rgensen Dx-Rx Institute 3480 FredensborgDenmark

Amplification of the human epidermal growth factor receptor 2 (HER2) gene and overexpression of the HER2 protein is found in 15%-20% of patients with gastric and gastroesophageal junction cancer. The degree of HER2 overexpression and amplification varies with the location of the carcinoma, with higher expression in the gastroesophageal and proximal parts compared to the distal parts of the stomach. Further, HER2 overexpression and amplification also seems to be related to the Lauren histological classification, with higher levels found in the intestinal phenotype compared to the diffuse and mixed types. The prognostic properties of HER2 overexpression and amplification are still under debate, but a large number of studies seem to indicate that HER2 is a negative prognostic factor. The usefulness of HER2 targeted therapy in gastric cancer was demonstrated in the ToGA trial, where HER2-positive patients with advanced gastric and gastroesophageal junction adenocarcinoma were randomized to receive 5-FU/capecitabine and cisplatin, either alone or in combination with trastuzumab. A statically significant gain in overall survival was seen in patients who received the combined treatment of trastuzumab and chemotherapy. Patients with a strong overexpression of the HER2 protein (IHC3+) specifically benefited from the treatment, with a median overall survival of 17.9 mo. As a consequence of the positive results of the ToGA trial, patients with advanced gastric or gastroesophageal junction adenocarcinoma are now routinely tested for HER2. The ToGA trial must be characterized as a landmark in the treatment of gastric cancer and it has paved the way for a number of new HER2 targeted compounds such as pertuzumab, ado-trastuzumab emtansine, lapatinib, afatinib, and dacomitinib, which are currently undergoing phase II and III clinical testing. Overall, this review will discuss the current status of HER2 in gastric and gastroesophageal junction cancer and the future direction in rela

关键词： Human epidermal growth factor receptor 2 Gastric cancer Prognostic Companion diagnostics trastuzumab Pertuzumab Ado-trastuzumab emtansine Lapatinib