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Frontiers of Structural and Civil Engineering 2016年第4期10卷 462-471页

作者： Xiao-ping BAI ya-nan LIU System Engineering Research Institute School of Management Xi 'an University of Architecture & Technology Xi 'an 710055 China

Dynamic reliability is a very important issue in reliability research. The dynamic reliability analysis for the project is still in search of domestic and international research in the exploration stage. By now, dynamic reliability research mainly concentrates on the reliability assessment; the methods mainly include dynamic fault tree, extension of event sequence diagram and Monte Carlo simulation, and et al. The paper aims to research the dynamic reliability optimization. On the basis of analysis of the four quality influence factors in the construction engineering, a method based on gray correlation degree is employed to calculate the weights of factors affecting construction process quality. Then the weights are added into the reliability improvement feasible index （RIFI）. Furthermore, a novel nonlinear programming mathematic optimization model is established. In the Insight software environment, the Adaptive Simulated Annealing （ASA） algorithm is used to get a more accurate construction subsystem optimal reliability under different RIFI conditions. In addition, the relationship between construction quality and construction system reliability is analyzed, the proposed methods and detailed processing can offer a useful reference for improving the construction system quality level.

关键词： civil engineering dynamic reliability grey relational degree adaptive simulated annealing algorithm

A mathematical model of cortical bone remodeling at cellular level under mechanical stimulus

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Acta Mechanica Sinica 2012年第6期28卷 1678-1692页

作者： Qing-Hua Qin ya-nan Wang Research School of Engineering The Australian National University

A bone cell population dynamics model for cor- tical bone remodeling under mechanical stimulus is devel- oped in this paper. The external experiments extracted from the literature which have not been used in the creation of the model are used to test the validity of the model. Not only can the model compare reasonably well with these ex- perimental results such as the increase percentage of final values of bone mineral content （BMC） and bone fracture en- ergy （BFE） among different loading schemes （which proves the validity of the model）, but also predict the realtime devel- opment pattern of BMC and BFE, as well as the dynamics of osteoblasts （OBA）, osteoclasts （OCA）, nitric oxide （NO） and prostaglandin E2 （PGE2） for each loading scheme, which can hardly be monitored through experiment. In conclusion, the model is the first of its kind that is able to provide an in- sight into the quantitative mechanism of bone remodeling at cellular level by which bone cells are activated by mechan- ical stimulus in order to start resorption/formation of bone mass. More importantly, this model has laid a solid foun- dation based on which future work such as systemic control theory analysis of bone remodeling under mechanical stimu- lus can be investigated. The to-be identified control mecha- nism will help to develop effective drugs and combined non- pharmacological therapies to combat bone loss pathologies. Also this deeper understanding of how mechanical forces quantitatively interact with skeletal tissue is essential for the generation of bone tissue for tissue replacement purposes in tissue engineering.

关键词： Cortical bone remodeling Cell population dy-namics Mechanotransduction Mechanosensitivity Bonefracture energy - Bone mineral content

Experimental Study on Cooling Down Process of a Nitrogen-Charged Cryogenic Loop Heat Pipe

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Journal of Thermal Science 2023年第1期32卷 153-165页

作者： ZHAO ya'nan yaN Tao LIANG Jingtao Key Laboratory of Space Energy Conversion Technology Technical Institute of Physics and ChemistryChinese Academyof SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China

Cryogenic loop heat pipes are highly efficient heat transfer devices at cryogenic temperature range,which have promising application prospects in satellites,spacecrafts,electronics,and so *** down process is a most critical process for a CLHP before *** present,secondary loop is a major way for a CLHP to fulfil cooling down and most studies are concentrated on heat transfer characteristics during normal ***,few investigations have been carried out on the cooling down *** this paper,the cooling down process of a nitrogen-charged CLHP assisted with a secondary loop was experimentally investigated.A simple qualitative approach to estimate the cooling down time was proposed according to the law of conservation of *** two flow paths of the working fluid in the CLHP during the cooling down process were *** studies on the cooling down process with various secondary heat loads and working fluid inventory were presented in *** the increase of secondary heat load,the elapsed time of Stage III decreased significantly due to the larger mass flow rate in Path *** addition,the effect of the working fluid inventory on the cooling down time was generally small in the range from 2.99 MPa to 3.80 ***,with 2.80 MPa working fluid inventory,it required much longer cooling down time,which was because of the lack of liquid in the CLHP with low working fluid ***,the influence of gravity on the temperature variation of the components during the experiments was *** work is beneficial for better understanding of the cooling down process and optimizing of CLHPs.

关键词： cryogenic loop heat pipe secondary loop cooling down heat transfer

Experimental Investigation on Thermal Characteristics of Long Distance Loop Heat Pipes

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Journal of Thermal Science 2022年第3期31卷 741-750页

作者： ZHAO ya’nan yaN Tao LIANG Jingtao Key Laboratory of Space Energy Conversion Technology Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100190China

Loop heat pipes(LHPs)are attractive two-phase thermal control devices for satellites,electronics and many other *** are capable of transporting heat efficiently for long distances up to several meters at any *** paper investigated the heat transfer characteristics of loop heat pipes with long distances and small diameter transport *** stainless steel tubes of 2 mm and 3 mm in inner diameters were chosen as liquid lines and vapor lines of the *** local thermal resistances in the evaporator of the 6 m-LHP were researched and analyzed,which indicated that the thermal resistance between the aluminum block and the vapor in the vapor channel accounted for a major proportion of the total thermal *** effect of heat sink temperatures on the performance of the 6 m-LHP were compared with 10°C,15°C,20°C and 25°C cooling water ***,the thermal characteristics of LHPs with transport distances of 2 m and 16 m were also experimentally *** 16 m-LHP could achieve a heat transfer capacity of 100 W and the 2 m-LHP could reach more than 339 W,on the premise of the evaporator temperature below 100°*** thermal resistance of the 2 m-LHP could achieve 0.125°C/W.

关键词： loop heat pipe thermal management heat transport long distance thermal resistance

Flexible double narrowband near-infrared photodetector based on PMMA/core-shell upconversion nanoparticle composites

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Journal of Rare Earths 2022年第2期40卷 211-217,I0002页

作者： ya’nan Ji Donglei Zhou nan Wang nan Ding Wen Xu Hongwei Song State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China

Flexible narrowband near infrared(NIR)photodetectors(PDs)are urgently in demand in the fastdeveloping era of flexible electronics,due to their crucial roles in various innovative ***,we designed and synthesized the core-shell structured NaYF4:Yb^(3+),Er^(3+)@NaYF4:Nd^(3+)upconversion nanoparticles(UCNPs),which can be pumped by the 808 and 980 nm *** upconversion luminescence(UCL)are significantly enhanced after being assembled with the opal photonic crystals(OPCs)due to the photonic crystal effect,with 55 and 48 folds of enhancement factors under illuminations of 808 and 980 nm lights,*** on this hybrid,the flexible narrowband PDs were successfully fabricated on the PET substrate with the structure of OPCs/NaYF4:Yb^(3+),Er^(3+)@Nd^(3+)/MAPbl3,which displays excellent detection performance to double narrowband NIR light(808 and 980 nm)benefiting from the amplified UCL,with responsivity of 8.79 and 7.39 A/W,detectivity of 3.01×10^(11)and2.68×10^(11)cm·Hz^(1/2)/W for 808 and 980 nm lights detection respectively,along with short response time in the range of 120-160 ***,the OPCs/NaYF4:Yb^(3+),Er^(3+)@NaYF4:Nd^(3+)/MAPbI3 double narrowband PDs display low photodetection power threshold(0.05 W/cm2),outstanding flexibility,prominent moisture resistance,and good long-time *** work displays a new concept of narrowband NIR PDs,which open a new field for specific NIR light detections.

关键词： Upconversion luminescence Upconversion enhancement Narrow-band near-infrared photodetection Flexible photodetectors Rare earths

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毫火针治疗颈性眩晕的临床疗效观察

中华中医药杂志 2019年第11期34卷 5506-5509页

作者：傅敏吕亚南钟维章谢爱泽梁淑芬王程高新刘朝锋黄沃宁罗扬韦立书朱维汉广西中医药大学针灸推拿学院南宁530200 广西壮族自治区人民医院康复医学中心南宁530021 广西壮族自治区人民医院神经内科南宁530021 广西医科大学第一附属医院南宁530021

目的:观察毫火针治疗颈性眩晕的临床疗效。方法:选取2014年7月到2016年9月就诊的60例颈性眩晕患者,按随机数字表法分为治疗组和对照组,每组30例。治疗组采用毫火针治疗,隔日1次,共治疗3次;对照组采用口服西比灵胶囊治疗,每日10mg,共服2... 详细信息

目的:观察毫火针治疗颈性眩晕的临床疗效。方法:选取2014年7月到2016年9月就诊的60例颈性眩晕患者,按随机数字表法分为治疗组和对照组,每组30例。治疗组采用毫火针治疗,隔日1次,共治疗3次;对照组采用口服西比灵胶囊治疗,每日10mg,共服2周。比较两组治疗前后《颈性眩晕症状与功能评估量表》《中医眩晕程度分级评价表》及《颈椎病疗效评价表》得分情况。治疗结束后6个月,比较两组的复发率。结果:治疗后两组《颈性眩晕症状与功能评估量表》评分均较本组治疗前显著升高(P<0.01),且治疗组升高幅度大于同期对照组(P<0.01);治疗后两组《中医眩晕程度分级评价表》和《颈椎病疗效评价表》均较本组治疗前显著降低(P<0.01),且治疗组降低幅度大于同期对照组(P<0.01)。治疗组复发率为6.67%显著低于对照组的73.33%(P<0.01)。结论:毫火针与口服西比灵胶囊对颈性眩晕患者均有效,但毫火针疗效优于口服西比灵胶囊,且复发率低。

关键词：颈性眩晕毫火针经脉理论经筋理论枕下三角西比灵

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

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Neural Regeneration Research 2025年第8期20卷 2199-2217页

作者： Zi Ye Runqing Liu Hangxing Wang Aizhen Zuo Cen Jin nan Wang Huiqi Sun Luqian Feng Hua yang The Clinical Medical College Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Infectious Diseases Department of Internal MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina School of Medical Imaging Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Gastroenterology First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina The Second Clinical Medical College Lanzhou UniversityLanzhouGansu ProvinceChina Department of Neurosurgery Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou ProvinceChina

Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient's condition;this phenomenon is known as cerebral ischemia-reperfusion *** studies have elucidated the neuroprotective role of the sirtuin protein family(Sirtuins)in modulating cerebral ischemia-reperfusion ***,the potential of utilizing it as a novel intervention target to influence the prognosis of cerebral ischemia-reperfusion injury requires additional *** this review,the origin and research progress of Sirtuins are summarized,suggesting the involvement of Sirtuins in diverse mechanisms that affect cerebral ischemia-reperfusion injury,including inflammation,oxidative stress,blood-brain barrier damage,apoptosis,pyroptosis,and *** therapeutic avenues related to Sirtuins that may improve the prognosis of cerebral ischemia-reperfusion injury were also investigated by modulating Sirtuins expression and affecting representative pathways,such as nuclear factor-kappa B signaling,oxidative stress mediated by adenosine monophosphate-activated protein kinase,and the forkhead box *** review also summarizes the potential of endogenous substances,such as RNA and hormones,drugs,dietary supplements,and emerging therapies that regulate Sirtuins *** review also reveals that regulating Sirtuins mitigates cerebral ischemia-reperfusion injury when combined with other risk *** Sirtuins show promise as a potential target for the treatment of cerebral ischemiareperfusion injury,most recent studies are based on rodent models with circadian rhythms that are distinct from those of humans,potentially influencing the efficacy of Sirtuinstargeting drug ***,this review provides new insights into the role of Sirtuins in the pathology and treatment of cerebral ischemia-reperfusion injury.

关键词： apoptosis autophagy blood-brain barrier dietary supplements drug hormones inflammation neuroprotection oxidative stress prognosis pyroptosis reperfusion injury risk factors RNA therapeutics

Perturbed magnetic field of an infinite plate with a centered crack

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Acta Mechanica Sinica 2011年第2期27卷 259-265页

作者： Fei Qin yang Zhang ya-nan Liu College of Mechanical Engineering and Applied Electronics Technology Beijing University of Technology 100124 Beijing China

Deforming a cracked magnetoelastic body in a magnetic field induces a perturbed magnetic field around the crack. The quantitative relationship between this perturbed field and the stress around the crack is crucial in developing a new generation of magnetism-based nondestructive testing technologies. In this paper, an analytical expression of the perturbed magnetic field induced by structural deforma- tion of an infinite ferromagnetic elastic plate containing a centered crack in a weak external magnetic field is obtained by using the linearized magnetoelastic theory and Fourier transform methods. The main finding is that the perturbed magnetic field intensity is proportional to the applied tensile stress, and is dominated by the displacement gradient on the boundary of the magnetoelastic solid. The tangential component of the perturbed magnetic-field intensity near the crack exhibits an antisymmetric distribution along the crack that reverses its direction sharply across its two faces, while the normal component shows a symmetric distribution along the crack with singular points at the crack tips.

关键词： Magnetoelasticity Crack Perturbed magnetic field Fourier transform method Nondestructive testing

二维光晶格中旋转玻色-爱因斯坦凝聚基态中的涡旋分布

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原子与分子物理学报 2025年第1期42卷 118-126页

作者：张志强王平平吕亚南郑州商学院大学物理教研室郑州451200

利用多重网格预条件共轭梯度法,研究了囚禁在二维光晶格与谐振势组成的复合势阱中的旋转玻色-爱因斯坦凝聚体中的涡旋分布,探讨了光晶格深度、晶格常数和凝聚体旋转频率对旋转凝聚体中涡旋分布的影响.结果表明,由于光晶格势阱的引入,凝... 详细信息

利用多重网格预条件共轭梯度法,研究了囚禁在二维光晶格与谐振势组成的复合势阱中的旋转玻色-爱因斯坦凝聚体中的涡旋分布,探讨了光晶格深度、晶格常数和凝聚体旋转频率对旋转凝聚体中涡旋分布的影响.结果表明,由于光晶格势阱的引入,凝聚体中产生涡旋,且涡旋位于外部势阱极小值处.随着光晶格势阱深度的增加,凝聚体集聚在光晶格势阱的底部,形成格点状分布,其中的涡旋形成涡旋对,并融合形成更大的涡旋.在晶格常数较小时,凝聚体中涡旋分布形成类似Abrikosov涡旋晶格,随着晶格常数的增加,凝聚体中涡旋的分布形式出现多样化,出现了内中外三层结构.随着旋转频率的增加,凝聚体中涡旋数目也随之增加,涡旋分布也更加复杂和富于变化,凝聚体密度分布范围也随着旋转频率的增加而扩展.当凝聚体旋转频率接近外部谐振势阱的谐振频率,即凝聚体处于最低朗道能级近似时,其中的涡旋数量大幅度增加,且出现涡旋成对组合与融合现象,并形成了涡旋斑图花纹.

关键词：波色-爱因斯坦凝聚涡旋二维光晶格复合势阱

Microfluidic production of liposomes through liquid-liquid phase separation in ternary droplets

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Frontiers of Chemical Science and Engineering 2022年第6期16卷 1017-1022页

作者： Xu-Chun Song Zi-Han Zhou ya-Lan Yu nan-nan Deng College of Chemistry and Chemical Engineering Southwest Petroleum UniversityChengdu 610500China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Liposomes,the self-assembled phospholipid vesicles,have been extensively used in various fields such as artificial cells,drug delivery systems,biosensors and ***,current microfluidic routes to liposomes mostly rely on water-in-oil-in-water double emulsion droplets as templates,and require complex fabrication of microfluidic devices,and tedious manipulation of multiphase *** we present a simple microfluidic approach to preparing monodisperse liposomes from oil-in-water *** demonstration,we used butyl acetate-water-ethanol ternary mixtures as inner phase and an aqueous solution of surfactants as outer phase to make oil-in-water droplets,which can evolve into water-in-oil-in-water double emulsion droplets by liquid-liquid phase separation of ternary ***,the resultant water-in-oil-in-water droplets underwent a dewetting transition to form separated monodisperse liposomes and residual oil droplets,with the assistance of *** method is simple,does not require complex microfluidic devices and tedious manipulation,and provides a new platform for controllable preparation of liposomes.

关键词： microfluidics liposomes ternary droplets phase separation