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Response of Bacterial Community and Enzyme Activity of Greenhouse Tomato under Different Irrigation Systems

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1543-1568页

作者： Haijian Yang Mingzhi Zhang na xiao Yuan Li Faculty of Engineering Huanghe Science and Technology UniversityZhengzhou450063China Northwest Land and Resources Research Center Shaanxi Normal UniversityXi’an710119China

The micro-sprinkler irrigation mulched(MSM)has been suggested as a novel water-saving approach in con-trolled environment ***,the effects of microbial community structure and enzyme activity in the rhizosphere soil on crop growth under MSM remain *** study conducted a randomized experimen-tal design using greenhouse tomatoes to investigate changes in bacterial community structure and enzyme activity in rhizosphere soil under different irrigation frequencies(F)and amounts(I)of ***ﬁndings revealed that with the increase of F or I,The total count of soil bacteria in tomatoesﬁrst rose and then fell in terms of Opera-tional Taxonomic Units(OTUs)classiﬁ*** to other F,the most abundance of nitrogen and phos-phorus metabolism genes and enzyme activities were observed with a 5-day ***,the diversity of soil bacterial community structure initially rose before eventually declining with the increase of the *** 1.00 Epan(cumulative evaporation of a 20 cm standard pan)under MSM helped boost the abundance of nitrogen and phosphorus metabolism functional genes in soil bacteria,ensuring higher enzyme activities related to nitro-gen,carbon,and phosphorus metabolism in the rhizosphere soil of ***’yield initially rose before eventually declining with the increase in F or I,whereas I had a more signiﬁcant effect on yield.A 1.00%increase in I yielded a minimum of 39.24%increase in tomato *** study showed a positive correlation between soil bacterial community,soil enzyme activity,and greenhouse tomato yield under *** the results comprehensively,the combined irrigation mode of F of 5 d and I of 1.00 Epan was recommended for greenhouse tomatoes under *** conclusion provides theoretical support for water-saving practices and yield improve-ment in facility agriculture,especially tomato cultivation.

关键词： Greenhouse tomato yield bacterial community enzyme activity model

Efficacy and safety of electroacupuncture for insomnia:A systematic review and meta-analysis

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Journal of Integrative Medicine 2024年第4期22卷 459-472页

作者： Han-yu Xu Lin-na Wu Yuan Zhang Te Ba xiao-feng Zhao Acupuncture and Moxibustion Department First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300193China national Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Tianjin 300193China

Background:Electroacupuncture is often used to treat ***:To evaluate the efficacy and safety of electroacupuncture for *** strategy:Databases including PubMed,Cochrane Library,Embase,Web of Science,Chinese Biomedical Literature Database,China national Knowledge Infrastructure,Wanfang Data and VIP Fulltext e-Journals Database were searched up to January 15,*** criteria:Randomized clinical trials were included if they compared the clinical efficacy and safety of electroacupuncture with sham acupuncture,no treatment or usual care (UC) and general *** extraction and analysis:The full texts of the studies were reviewed to remove ineligible *** extracted data included authors,publication year,diagnostic criteria,sample size,population characteristics,interventions and *** above steps were performed independently by two reviewers and the data were cross ***15.0 software was used to analyze the extracted outcome *** continuous data (Pittsburgh Sleep Quality Index[PSQI]score and Insomnia Severity Index score),weighted mean difference (WMD) was calculated and 95% confidence interval (CI) was reported when the same scale was *** dichotomous variables (clinical response rate and adverse events),a meta-analysis was performed using risk ratio (RR) as the effect ***:Thirty-one trials with 2226 subjects were *** meta-analysis suggested that electroacupuncture was more effective in improving insomnia compared with the control group (sham acupuncture,no treatment,UC and general acupuncture)(RR=1.21;95 CI:[1.16,1.27]),significantly reducing the PSQI score in insomnia patients after treatment and at follow-up (WMD=-3.23;95%CI:[-4.29,-2.17];P<0.001).There was no significant difference in the incidence of adverse events between the EA and control groups (sham acupuncture and no treatment or ***=1.48;95%CI:[0.91,2.40];P=0.117).In addition,the regression results revealed t

关键词： Electroacupuncture Insomnia Systematic review Meta-analysis

Etching-free pixel definition in InGaN green micro-LEDs

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Light(Science & Applications) 2024年第8期13卷 1655-1665页

作者： Zhiyuan Liu Yi Lu Haicheng Cao Glen Isaac Maciel Garcia Tingang Liu xiao Tang na xiao Raul Aguileta Vazquez Mingtao Nong xiaohang Li Advanced Semiconductor Laboratory Electrical and Computer Engineering ProgramCEMSE DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia

The traditional plasma etching process for defining micro-LED pixels could lead to significant sidewall *** near sidewall regions act as non-radiative recombination centers and paths for current leakage,significantly deteriorating device *** this study,we demonstrated a novel selective thermal oxidation(STO)method that allowed pixel definition without undergoing plasma damage and subsequent dielectric *** annealing in ambient air oxidized and reshaped the LED structure,such as p-layers and InGaN/GaN multiple quantum ***,the pixel areas beneath the pre-deposited SiO_(2)layer were selectively and effectively *** was demonstrated that prolonged thermal annealing time enhanced the insulating properties of the oxide,significantly reducing LED leakage ***,applying a thicker SiO_(2)protective layer minimized device resistance and boosted device efficiency *** the STO method,InGaN green micro-LED arrays with 50-,30-,and 10-μm pixel sizes were manufactured and *** results indicated that after 4 h of air annealing and with a 3.5-μm SiO_(2)protective layer,the 10-μm pixel array exhibited leakage currents density 1.2×10^(-6)A/cm^(2)at-10 V voltage and a peak on-wafer external quantum efficiency of~6.48%.This work suggests that the STO method could become an effective approach for future micro-LED manufacturing to mitigate adverse LED efficiency size effects due to the plasma etching and improve device ***-LEDs fabricated through the STO method can be applied to micro-displays,visible light communication,and optical interconnect-based *** planar pixel geometry will provide more possibilities for the monolithic integration of driving circuits with ***,the STO method is not limited to micro-LED fabrication and can be extended to design other III-nitride devices,such as photodetectors,laser diodes,high-electron-mobility transistors

关键词： annealing protective quantum

Clinical value of precise rehabilitation nursing in management of cerebral infarction

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World Journal of Clinical Cases 2024年第1期12卷 24-31页

作者： Ya-na Xu Xiu-Zhen Wang xiao-Rong Zhang Department of Neurology Wuhan Fourth HospitalWuhan 430030Hubei ProvinceChina Department of Neurosurgery The First People's Hospital of Jiangxia DistrictWuhan City(Union Jiangnan Hospital of Huazhong University of Science and Technology)Wuhan 430200Hubei ProvinceChina

BACKGROUND Cerebral infarction,previously referred to as cerebral infarction or ischemic stroke,refers to the localized brain tissue experiencing ischemic necrosis or softening due to disorders in brain blood supply,ischemia,and *** precision rehabilitation nursing model for chronic disease management is a continuous,fixed,orderly,and efficient nursing model aimed at standardizing the clinical nursing process,reducing the wastage of medical resources,and improving the quality of medical *** To analyze the value of a precise rehabilitation nursing model for chronic disease management in patients with cerebral *** Patients(n=124)admitted to our hospital with cerebral infarction between November 2019 and November 2021 were enrolled as the study *** random number table method was used to divide them into a conventional nursing intervention group(n=61)and a model nursing intervention group(n=63).Changes in the nursing index for the two groups were compared after conventional nursing intervention and precise rehabilitation intervention nursing for chronic disease *** Compared with the conventional intervention group,the model intervention group had a shorter time to clinical symptom relief(Pnagement improves the clinical symptoms of patients with cerebral infarction,reducing the incidence of total complications and improving the clinical outcome of patients,and is worthy of application in clinical practice.

关键词： Precise rehabilitation nursing model for chronic disease management Cerebral infarction Knowledge of disease Safety and quality

Effect of Maternal DEHP Exposure on Lipid Metabolism in Adult Male Rats and the Antagonistic Effect of Genistein

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Biomedical and Environmental Sciences 2024年第3期37卷 315-319页

作者： ZHANG Yun Bo LI Jiang Li TIAN Jie na xiao Lin Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150081HeilongjiangChina

Lipid metabolism refers to the biochemical processes involved in synthesising,storing,utilising,and breaking down lipids in living *** are essential for various physiological functions,including energy storage,insulation,protection of organs,and the formation of cell *** in lipid metabolism can lead to a number of health issues,such as atherosclerosis,obesity,and type 2 diabetes,etc.[1].Environmental factors,genetics,and lifestyle factors are some of the factors that can contribute to the development of ***,there is a growing academic interest in the impact of environmental factors.

关键词： Lipid metabolism organs

Transcatheter arterial chemoembolization combined with PD-1 inhibitors and Lenvatinib for hepatocellular carcinoma with portal vein tumor thrombus

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World Journal of Gastroenterology 2024年第8期30卷 843-854页

作者： Hong-xiao Wu xiao-Yan Ding Ya-Wen Xu Ming-Hua Yu xiao-Mi Li na Deng Jing-Long Chen Cancer Center Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China

BACKGROUND Hepatocellular carcinoma(HCC)patients complicated with portal vein tumor thrombus(PVTT)exhibit poor prognoses and treatment *** To investigate efficacies and safety of the combination of PD-1 inhibitor,transcatheter arterial chemoembolization(TACE)and Lenvatinib in HCC subjects comorbid with *** From January 2019 to December 2020,HCC patients with PVTT types Ⅰ-Ⅳ were retrospectively enrolled at Beijing Ditan *** were distributed to either the PTL or TACE/Lenvatinib(TL)*** median progression-free survival(mPFS)was set as the primary endpoint,while parameters like median overall survival,objective response rate,disease control rate(DCR),and toxicity level served as secondary *** Forty-one eligible patients were finally recruited for this study and divided into the PTL(n=18)and TL(n=23)*** a median follow-up of 21.8 months,the DCRs were 88.9%and 60.9%in the PTL and TL groups(P=0.046),***,mPFS indicated significant improvement(HR=0.25;P<0.001)in PTL-treated patients(5.4 months)compared to TL-treated(2.7 months)*** were no treatment-related deaths or differences in adverse events in either *** A triplet regimen of PTL was safe and well-tolerated as well as exhibited favorable efficacy over the TL regimen for advanced-stage HCC patients with PVTT types Ⅰ-Ⅳ.

关键词： Hepatocellular carcinoma Transcatheter arterial chemoembolization Lenvatinib PD-1 inhibitor Portal vein tumor thrombus

Role of aminopeptidase N-like in the acquisition of begomoviruses by Bemisia tabaci,the whitefly vector

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Insect Science 2024年第3期31卷 707-719页

作者： Yun-Yun Fan Yao Chi na Chen Wilmer J.Cuellar xiao-Wei Wang Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang ProvinceInstitute of Insect SciencesZhejiang UniversityHangzhouChina Zhejiang Tianmushan national nature Reserve Administration HangzhouChina Institute of Plant Protection Liaoning Academy of Agricultural SciencesShenyangChina Virology Laboratory Cassava ProgramInternational Center for Tropical Agriculture(CIAT)PalmiraColombia

Sri Lankan cassava mosaic virus(SLCMV)is a prominent causative agent of cassava mosaic disease in Asia and relies on the whitefly Bemisia tabaci cryptic complex for its ***,the molecular mechanisms involved in SLCMV transmission by *** have yet to be *** this study,we identified an aminopeptidase N-like protein(BtAPN)in *** Asia II 1,an efficient vector of SLCMV,which is involved in the SLCMV transmission *** the use of glutathione S-transferase pull-down assay and LC-MS/MS analysis,we demonstrated the interaction between BtAPN and the coat protein(CP)of *** interaction was further confirmed in vitro,and we observed an induction of BtAPN gene expression following SLCMV *** interfering with the function of BtAPN,the quantities of SLCMV were significantly reduced in various parts of *** Asia II 1,including the whole body,midgut,hemolymph,and primary salivary ***,we discovered that BtAPN is conserved in *** Middle East-Asia Minor 1(MEAM1)and interacts with the CP of tomato yellow leaf curl virus(TYLCV),a begomovirus known to cause severe damage to tomato *** BtAPN with antibody led to a significant reduction in the quantities of TYLCV in whitefly whole body and organs/*** results demonstrate that BtAPN plays a generic role in interacting with the CP of begomoviruses and positively regulates their acquisition by the whitefly.

关键词： BtAPN coat protein SLCMV TYLCV virus acquisition whitefly

Predictive effect of lipopolysaccharide-stimulated inflammatory cytokines on symptoms of generalized anxiety disorder

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World Journal of Psychiatry 2024年第9期14卷 1308-1318页

作者： Wen-Yuan Wang na Liu xiao-xiao Qi Bing Han Jing-na Sun Zheng-Li Chen Ming-Wei Wang Yan-Yong Wang Department of Neurology The First Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Neurology Hebei HospitalXuanwu HospitalCapital Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Neurological Examination at Treatment Center The First Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Clinical Laboratory The First Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Generalized anxiety disorder(GAD)is a relatively common mental ***,inflammation,an important factor for the development of depression,has attracted increasing *** studies have shown that inflammatory cytokines can affect the pathophysiological processes of several nervous system *** hypothesized that there is a correlation between the levels of lipopolysaccharide(LPS)-stimulated inflammatory cytokines and the clinical symptoms of *** To investigate the predictive effect of LPS-stimulated inflammatory cytokines on symptoms of *** This was a cross-sectional study in which 89 patients with GAD diagnosed at The First Hospital of Hebei Medical University from January 2022 to December 2022 and 70 individuals without anxiety and depression(controls)during the same period were *** venous blood was collected from all the subjects in heparin tubes,and another 3 ml of blood was supplemented with LPS(10 ng/ml).The plasma levels of 12 cytokines[Interleukin(IL)-1β,IL-2,IL-4,IL-5,IL-6,IL-8,IL-10,tumor necrosis factor(TNF)-α,interferon(IFN)-γ,IL-17A,IL-12p70,and IFN-α]were *** Post-LPS stimulation,the levels of IL-1β,IL-6,IL-8,IL-10,and TNF-αin both the control and GAD groups were significantly elevated above those in the nonstimulated groups,with IL-6 and IL-8 showing marked *** in IL-8 and TNF-αwere statistically significant in the GAD group(Pnalysis revealed that TNF-αwas associated with mental anxiety,whereas IL-1β,IL-8,and IL-10 were associated with physical anxiety symptoms,with IL-10 showing a negative correlation with physical ***-6 was associated with both mental and physical aspects of *** The physical symptoms of GAD are related to infla

关键词： Lipopolysaccharide Cytokine Generalized anxiety disorder Inflammatory cytokines Anxiety

Rna m6A dynamic modification mediated by nucleuslocalized FTO is involved in follicular reserve

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Zoological Research 2024年第2期45卷 415-428页

作者： Jiao-na Zhang Rui-Ting Wang Francesca-Gioia Klinger Shun-Feng Cheng Wei Shen xiao-Feng Sun College of Life Sciences Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of ShandongQingdao Agricultural UniversityQingdaoShandong 266109China Department of Biomedicine and Prevention University of Rome Tor VergataRome 00133Italy

In eukaryotic organisms,the most common internal modification of messenger Rna(m Rna)is N6-methyladenosine(m6A).This modification can be dynamically and reversibly controlled by specific enzymes known as m6A writers and *** fat-mass and obesity-associated protein(FTO)catalyzes Rna demethylation and plays a critical role in various physiological and pathological *** research identified dynamic alterations in both m6A and FTO during the assembly of primordial follicles,with an inverse relationship observed for m6A levels and nuclear-localized FTO *** of Fto small interfering Rna(si Rna)altered the expression of genes related to cell proliferation,hormone regulation,and cell chemotaxis,and affected Rna alternative *** of the full-length Fto gene led to changes in m6A levels,alternative splicing of Cdk5,cell proliferation,cell cycle progression,and proportion of primordial ***,overexpression of Fto lacking a nuclear localization signal(NLS)did not significantly alter m6A levels or primordial follicle *** findings suggest that FTO,localized in the nucleus but not in the cytoplasm,regulates Rna m6A demethylation and plays a role in cell proliferation,cell cycle progression,and primordial follicle *** results highlight the potential of m6A and its eraser FTO as possible biomarkers and therapeutic targets.

关键词： m6A FTO Ovary Primordial follicle assembly Alternative splicing