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Research Progress in Astragalus Membranaceus and Its Active Components on Immune Responses in Liver Fibrosis

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Chinese Journal of Integrative Medicine 2020年第10期26卷 794-800页

作者： LIU yu-tong lv Wen-liang Shaanxi University of Traditional Chinese Medicine Xianyang(712046)Shaanxi ProvinceChina Department of Infection Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijing(100053)China

The interaction between immune cells and hepatic stellate cells(HSCs)can modulate the development of hepatic *** can also regulate hepatic fibrosis and liver cirrhosis caused by excessive deposition of extracellular matrix(ECM).This article reviews the action mechanism of immune cells on liver fibrosis and the effect of Astragalus membranaeus and its active components on immune ***-depth study of interaction between immune cells and HSCs on the pathogenesis of liver fibrosis,and the regulatory effect of Astragalus membranaeus and its active components on immune mechanism will provide new insights in the treatment of liver fibrosis.

关键词： liver fibrosis immune cell Astragalus membranaceus review

Experimental study on simultaneous desulfurization and denitrifi- cation based on highly active absorbent

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Journal of Environmental Sciences 2006年第2期18卷 281-286页

作者： ZHAO Yi XU Pei-yao FU Dong huanG Jian-jun yu huan-huan School of Environmental Science and Engineering North China Electric Power University Baoding 071003 China

Simultaneous removal of SO2 and NO from flue gas by the highly active absorbent prepared from fly ash, lime and a few oxidizing manganese compound additive was studied using a flue gas circulating fluidized bed （CFB） under different experimental conditions. The effects influencing the removal effiencies were discussed. The optimal flue gas temperature, flue gas humidity, gas velocity of CFB and Ca/（S＋N） molar ratio with this process were approximately 110℃, 6%, 1.8 m/s and 1.05, respectively. Removal efficiencies of 92.3% for SO2 and 60.88% for NO were obtained under the optimal experimental conditions. While the spent absorbent appeared in the form of dry powder, the mechanism of removal for SO2 and NO based on the highly active absorbent was investigated by a scanning electron microscope （SEM）, a X-ray energy spectrometer and the chemical analysis methods. The valuable references can be provided for industrial application by the process. The foreground of application will be vast in China and in the world.

关键词： simultaneous desulfurization and denitrifieation CFB removal efficiency mechanism

Non-conventional peptides in plants:From gene regulation to crop improvement

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The Crop Journal 2023年第2期11卷 323-331页

作者： huan Chen Jingjuan yu Wen-Xue Li National Engineering Laboratory for Crop Molecular Breeding Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China State Key Laboratory of Agrobiotechnology College of Biological SciencesChina Agricultural UniversityBeijing 100193China

Conventional peptides(CPs)and non-conventional peptides(NCPs)are generated from small open reading frames,but most CPs are derived from large ***,which are derived from sequences other than conventional open reading frames or annotated coding sequences regions,function in plant development and adaptation to *** profiling,a technique for studying translational regulation,can be used to identify *** new technique,peptidogenomics,which integrates mass spectrometry and genomics,is becoming more widely used for identifying plant *** recent years,numerous studies have investigated the roles in monocots and dicots of miRNA-derived peptides and upstream open reading frames,which have potential for improving agronomic *** the biological functions of NCPs will advance molecular plant breeding by identifying regulators of plant growth and *** present an overview of NCP identification methods and recent findings about NCP biological functions.

关键词： NCPs Ribosome profiling Peptidogenomics miPEPs uORFs

Derivatives of Intersection Local Time for Two Independent Symmetricα-stable Processes

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1273-1292页

作者： huan ZHOU Guang Jun SHEN Qian yu Department of Mathematics Anhui Normal UniversityWuhu 241002P.R.China Department of Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 211106P.R.China Key Laboratory of Mathematical Modelling and High Performance Computing of Air Vehicles(NUAA) MIITNanjing 211106P.R.China

In this paper,we consider the derivatives of intersection local time for two independent d-dimensional symmetricα-stable processes X^(α) and X^(α)with respective indices α and α.We first study the sufficient condition for the existence of the derivatives,which makes us obtain the exponential integrability and H?lder *** we show that this condition is also necessary for the existence of derivatives of intersection local time at the ***,we also study the power variation of the derivatives.

关键词： Symmetric stable processes intersection local time exponential integrability power variation

Facile synthesis of porous germanium-iron bimetal oxide nanowires as anode materials for lithium-ion batteries

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Nano Research 2018年第7期11卷 3702-3709页

作者： Xiongwu Zhong Huijuan huan Xiaowu Liu Yan yu Key Laboratory of Materials for Energy Conversion Chinese Academy of Sciences (CAS) Department of Materials Science and Engineering University of Science and Technology of China Hefei 230026 China Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University Tianjin 300071 China State Key Laboratory of Fire Science University of Science and Technology of China Hefei 230026 China

Germanium-based oxide has been found to be a promising high-capacity anode material for lithium-ion batteries （LIBs）. However, it exhibits poor electrochemical performance because of the drastic volume change during cycling. Herein, we designed porous Ge-Fe bimetal oxide nanowires （Ge-Fe-Ox-700 NWs） by a large-scale and facile solvothermal reaction. When used as the anode material for LIBs, these Ge-Fe-Ox-700 NWs exhibited superior electrochemical performance （- 1,120 mAh·g^-1 at a current density of 100 mA·g^-1） and good cycling performance （- 750 mAh·g^-1 after 50 cycles at a current density of 100 mA·g^-1）. The improved performance is due to the small NW diameter, which allows for better accommodation of the drastic volume changes and zero-dimensional nanoparticles, which shorten the diffusion length of ions and electrons.

关键词： lithium-ion batteries anode materials germanium oxide iron oxide nanowires

Reliability-based design optimization of offshore wind turbine support structures using RBF surrogate model

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Frontiers of Structural and Civil Engineering 2023年第7期17卷 1086-1099页

作者： Changhai yu Xiaolong lv Dan huanG Dongju JIANG Department of Engineering Mechanics Hohai UniversityNanjing 211100China

An efficient reliability-based design optimization method for the support structures of monopile offshore wind turbines is proposed ***,parametric finite element analysis(FEA)models of the support structure are established by considering stochastic ***,a surrogate model is constructed using a radial basis function(RBF)neural network to replace the time-consuming *** uncertainties of loads,material properties,key sizes of structural components,and soil properties are *** uncertainty of soil properties is characterized by the variabilities of the unit weight,friction angle,and elastic modulus of *** reliability is determined via Monte Carlo simulation,and five limit states are considered,i.e.,structural stresses,tower top displacements,mudline rotation,buckling,and natural *** on the RBF surrogate model and particle swarm optimization algorithm,an optimal design is established to minimize the *** show that the proposed method can yield an optimal design that satisfies the target reliability and that the constructed RBF surrogate model significantly improves the optimization ***,the uncertainty of soil parameters significantly affects the optimization results,and increasing the monopile diameter is a cost-effective approach to cope with the uncertainty of soil parameters.

关键词： reliability-based design optimization offshore wind turbine parametric finite element analysis RBF surrogate model uncertain soil parameter

Reduce Training Error of Extreme Learning Machine by Selecting Appropriate Hidden Layer Output Matrix

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Journal of Systems Science and Systems Engineering 2021年第5期30卷 552-571页

作者： Yang lv Bang Li Jinghu yu Yiming Ding School of Science Wuhan University of TechnologyWuhan 430070China Center for Mathematical Sciences Wuhan University of TechnologyWuhan 430070China

Extreme learning machine(ELM)is a feedforward neural network with a single layer of hidden nodes,where the weight and the bias connecting input to hidden nodes are randomly *** output weight between hidden nodes and outputs are learned by a linear *** is interesting to ask whether the training error of ELM is significantly affected by the hidden layer output matrix H,because a positive answer will enable us obtain smaller training error from better *** single hidden layer feedforward neural network(SLFN)with one input neuron,there is significant difference between the training errors of different *** find there is a reliable strong negative rank correlation between the training errors and some singular values of the Moore-Penrose generalized inverse of *** on the rank correlation,a selection algorithm is proposed to choose robust appropriate H to achieve smaller training error among numerous *** experiments are carried out to validate the selection algorithm,including tests on real data *** results show that it achieves better performance in validity,speed and robustness.

关键词： ELM SLFNs training error Moore-Penrose generalized inverse selection algorithm

Solid–Liquid Composites with High Impact Resistance

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Acta Mechanica Solida Sinica 2021年第6期34卷 911-921页

作者： Miao yu Xiying Li Pengyu lv Huiling Duan Department of Mechanics and Engineering Science College of EngineeringPeking UniversityBeijing100871China CAPT HEDPS and IFSA Collaborative Innovation Center of MoEPeking UniversityBeijing100871China

Solid–liquid composites(SLCs)with novel thermal/electronic/mechanical properties imparted by programmable and functional liquid inclusions have attracted considerable research interest in recent years,and are widely used in smart electronics and soft *** feasible application of SLCs requires that they exhibit excellent static physical properties as well as dynamic impact resistance to satisfy complex service conditions,such as drops and *** paper examined the impact resistance of SLCs fabricated by using microfluidic 3D *** results of dynamic split-Hopkinson pressure bar(SHPB)tests showed that the performance of the fabricated SLCs improved in terms of energy dissipation and impact resistance compared with pristine *** case of dynamic impact in the strain rates ranging from 100 to 400s−1,the SLC specimen deformed without fracture,and its energy dissipation was dominated by the viscosity of the liquid *** dynamic impact in the strain rates ranging from 500 to 800s−1,the SLC specimen fractured and its energy dissipation was determined by the volume fraction of the liquid ***,the energy dissipation of the SLCs could be tuned by regulating the viscosity and volume fraction of the liquid inclusions to satisfy the requirements of protection against different strain ***,the process of fracture of the SLCs under the dynamic SHPB tests was recorded and analyzed by using a high-speed *** results showed that distributed liquid inclusions changed the paths of crack propagation to enhance energy dissipation in the *** study experimentally verified the enhancement in the energy dissipation of SLCs,and provided design strategies for developing multifunctional SLCs with high impact resistance.

关键词： Solid-liquid composites(SLCs) Impact resistance Dynamic SHPB Energy dissipation Fracturing process

Simulation, experimentation, and collaborative analysis of adjacent heat exchange modules in a vehicular cooling system

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2013年第6期14卷 417-426页

作者： yu-qi huanG Rui huanG Xiao-li yu Feng lv Power Machinery and Vehicular Engineering Institute Zhejiang University Department of Mechanical and Aerospace Engineering Monash University-Clayton

A cooling system consisting of several heat exchange modules is a necessary part of an automobile, and its performance has a direct effect on a vehicle's energy consumption. Heat exchangers, such as a charged air cooler (CAC), radiator, oil cooler, or condenser have different structures and can be arranged in various orders, and each combination may produce different effects because of interactions among them. In this study, we aimed to explore the principles governing interactions among adjacent heat exchangers in a cooling system, using numerical simulation and experimental technology. 3D models with different combinations were developed, compared, and analyzed comprehensively. A wind tunnel test platform was constructed to validate the computational results. We found that the heat dissipation of the modules was affected slightly by their relative position (the rules basically comply with the field synergy principle), but was independent of the modules' spacing within a certain distance range. The heat dissipation of one module could be effectively improved by restructuring, but with a penalty of higher resistance. However, the negative effect on the downstream module was much less than expected. The results indicated that the intensity of heat transfer depends not only on the average temperature difference between cold and hot mediums, but also on the temperature distribution.

关键词： Collaborative analysis Heat exchangers Field synergy principle Computational fluid dynamics (CFD) Wind tunnel