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System deployment optimization in architecture design

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Journal of Systems Engineering and Electronics 2014年第2期25卷 237-248页

作者： Xiaoxue Zhang Shu Tang aimin luo Xueshan luo School of Information System and Management National University of Defense Technology

Optimization of architecture design has recently drawn research interest. System deployment optimization （SDO） refers to the process of optimizing systems that are being deployed to activi- ties. This paper first formulates a mathematical model to theorize and operationalize the SDO problem and then identifies optimal so- lutions to solve the SDO problem. In the solutions, the success rate of the combat task is maximized, whereas the execution time of the task and the cost of changes in the system structure are mini- mized. The presented optimized algorithm generates an optimal solution without the need to check the entire search space. A novel method is finally proposed based on the combination of heuristic method and genetic algorithm （HGA）, as well as the combination of heuristic method and particle swarm optimization （HPSO）. Experi- ment results show that the HPSO method generates solutions faster than particle swarm optimization （PSO） and genetic algo- rithm （GA） in terms of execution time and performs more efficiently than the heuristic method in terms of determining the best solution.

关键词： architecture design system deployment optimization,heuristic.

An approach to measuring business-IT alignment maturity via DoDAF2.0

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Journal of Systems Engineering and Electronics 2020年第1期31卷 95-108页

作者： ZHANG Mengmeng CHEN Honghui MAO Yi luo aimin Science and Technology on Information Systems Engineering Laboratory National University of Defense TechnologyChangsha 410072China State Key Laboratory of Air Traffic Management System and Technology Nanjing 210014China

Measuring the business-IT alignment(BITA)of an organization determines its alignment level,provides directions for further improvements,and consequently promotes the organizational *** to the capabilities of enterprise architecture(EA)in interrelating different business/IT viewpoints and elements,the development of EA is superior to support BITA *** BITA measurement literature is sparse when it concerns *** literature tends to explain how EA viewpoints or models correlate with BITA,without discussing where to collect and integrate EA *** address this gap,this paper attempts to propose a specific BITA measurement process through associating a BITA maturity model with a famous EA framework:DoD Architectural Framework 2.0(DoDAF2.0).The BITA metrics in the maturity model are connected to the meta-models and models of *** illustrative ArchiSurance case is conducted to explain the measurement ***,this paper explores the process of BITA measurement from the viewpoint of EA,which helps to collect the measurement data in an organized way and analyzes the BITA level in the phase of architecture development.

关键词： business-IT alignment(BITA) measurement enterprise architecture(EA) DoD Architectural Framework 2.0(DoDAF2.0) meta-model

Functionality evaluation of system of systems architecture based on extended influence diagrams

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Journal of Systems Engineering and Electronics 2018年第3期29卷 510-518页

作者： ZHANG Mengmeng CHEN Honghui ZHANG Xiaoxue luo aimin LIU Junxian Science and Technology on Information Systems Engineering Laboratory National University of Defense TechnologyChangsha 410072China

System of systems architecture（SoSA） has received increasing emphasis by scholars since Zachman ignited its flame in 1987. Given its complexity and abstractness, it is critical to validate and evaluate SoSA to ensure requirements have been *** qualities are discussed in the literature of SoSA evaluation, while research on functionality is scarce. In order to assess SoSA functionality, an extended influence diagram（EID） is developed in this paper. Meanwhile, a simulation method is proposed to elicit the conditional probabilities in EID through designing and executing SoSA. An illustrative anti-missile architecture case is introduced for EID development, architecture design, and simulation.

关键词： system of systems architecture(SoSA) functionality evaluation extended influence diagram(EID) anti-missile architecture simulation

Modeling the dynamic alignment of business and information systems via the lens of human-centered architecture evolution

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Journal of Systems Engineering and Electronics 2021年第4期32卷 881-888页

作者： ZHANG Mengmeng YI Shuanghui CHEN Honghui luo aimin LIU Junxian ZHANG Xiaoxue Science and Technology on Information Systems Engineering Laboratory National University of Defense TechnologyChangsha 410072China National Key Laboratory for Complex System Simulation Military Academy of SciencesBeijing 100080China

The complexity of business and information systems(IS)alignment is a growing concern for researchers and practitioners *** extant research on alignment architecture fails to consider the human viewpoint,which makes it difficult to embrace emergent *** paper contributes to the extant literature in the following ***,we combine an enterprise architecture(EA)framework with a human viewpoint to address alignment issues in the architecture design phase;second,we describe a dynamic alignment model by developing a humancentered meta-model that explains first-and second-order changes and their effects on alignment *** paper provides better support for the theoretical research and the practical application of dynamic alignment.

关键词： business and information systems(IS)alignment human viewpoint enterprise architecture(EA) meta-model dynamic alignment

Retinoic acid alleviates rotavirus-induced intestinal damage by regulating redox homeostasis and autophagic flux in piglets

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Animal Nutrition 2024年第1期16卷 409-421页

作者： Xin Lai aimin Wu Bing Yu Hui Yan Junqiu luo Ping Zheng Jie Yu Daiwen Chen Institute of Animal Nutrition Sichuan Agricultural University Key Laboratory for Animal Disease-resistance Nutrition of China Ministry of Education Sichuan Agricultural University

Rotaviruses(RV) are a major cause of severe gastroenteritis, particularly in neonatal piglets. Despite the availability of effective vaccines, the development of antiviral therapies for RV remains an ongoing challenge. Retinoic acid(RA), a metabolite of vitamin A, has been shown to have anti-oxidative and antiviral properties. However, the mechanism by which RA exerts its intestinal-protective and antiviral effects on RV infection is not fully understood. The study investigates the effects of RA supplementation in Duroc × Landrace × Yorkshire(DLY) piglets challenged with RV. Thirty-six DLY piglets were assigned into six treatments, including a control group, RA treatment group with two concentration gradients(5and 15 mg/d), RV treatment group, and RV treatment group with the addition of different concentration gradients of RA(5 and 15 mg/d). Our study revealed that RV infection led to extensive intestinal architecture damage, which was mitigated by RA treatment at lower concentrations by increasing the villus height and villus height/crypt depth ratio(P < 0.05), enhancing intestinal stem cell signaling and promoting intestinal barrier functions. In addition, 15 mg/d RA supplementation significantly increased NRF2 and HO-1 protein expression(P < 0.05) and GSH content(P < 0.05), indicating that RA supplementation can enhance anti-oxidative signaling and redox homeostasis after RV challenge. Additionally,the research demonstrated that RA exerts a dual impact on the regulation of autophagy, both stimulating the initiation of autophagy and hindering the flow of autophagic flux. Through the modulation of autophagic flux, RA influence the progression of RV infection. These findings provide new insights into the regulation of redox hemostasis and autophagy by RA and its potential therapeutic application in RV infection.

关键词： Rotavirus Piglet Retinoic acid Intestinal barrier Redox hemostasis Autophagic flux

Secondary bile acids are associated with body lipid accumulation in obese pigs

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Animal Nutrition 2024年第3期18卷 246-256页

作者： Yaolian Hu aimin Wu Hui Yan Junning Pu Junqiu luo Ping Zheng Yuheng luo Jie Yu Jun He Bing Yu Daiwen Chen Key Laboratory of Animal Disease-Resistant Nutrition Ministry of EducationAnimal Nutrition InstituteSichuan Agricultural UniversityYa'an 625014China

The aim of this study was to investigate the reasons for the differences in lipid accumulation between lean and obese *** bile acids with varying levels within two types of pigs were found and then in vitro experiments were conducted to identify whether these bile acids can directly affect lipid *** pigs,including seven lean and seven obese pigs with body weights of approximately 80 kg,were fed the same diet at an amount approximately equivalent to 3%of their respective body weights daily for 42 *** vitro,3T3-L1 preadipocytes were cultured in medium with high glucose levels and were differentiated into mature adipocytes using differentiation ***,bile acids were added to mature adipocytes for 4 *** results showed that there was a difference in body lipids levels and gut microbiota composition between obese and lean pigs(P<0.05).According to the results of gut microbial function prediction,the bile acid biosynthesis in colonic digesta of obese pigs were different from that in lean ***-five bile acids were further screened by metabolomics,of which 4 were upregulated(P<0.05)and 2 were downregulated(P<0.05)in obese pigs compared to lean *** results of the correlation analysis demonstrated that chenodeoxycholic acid-3-β-D-glucuronide(CDCA-3Gln)andω-muricholic acid(ω-MCA)had a negative correlation with abdominal fat weight and abdominal fat rate,while isoallolithocholic acid(IALCA)was positively associated with crude fat in the liver and abdominal fat *** was a positive correlation between loin muscle area and CDCA-3Gln andω-MCA(P<0.05),however,IALCA and 3-oxodeoxycholic acid(3-oxo-DCA)were negatively associated with loin eye muscle area(P<0.05).Isoallolithocholic acid increased the gene expression of peroxisome proliferator-activated receptor gamma(PPARG)and the number of lipid droplets(P<0.05),promoting the lipid storage when IALCA was added to 3T3-L1 mature adipocytes in *** conclusion,the concentration of bile ac

关键词： Lean or obese pig Lipid accumulation Bile acid profile Gut microbiota

All-trans retinoic acid alleviates transmissible gastroenteritis virus-induced intestinal inflammation and barrier dysfunction in weaned piglets

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1131-1144页

作者： Junning Pu Daiwen Chen Gang Tian Jun He Ping Zheng Zhiqing Huang Xiangbing Mao Jie Yu Yuheng luo Junqiu luo Hui Yan aimin Wu Bing Yu Institute of Animal Nutrition Sichuan Agricultural UniversityChengdu 611130SichuanPeople’s Republic of China Key Laboratory of Animal Disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan Province611130 ChengduSichuanPeople’s Republic of China

Background Transmissible gastroenteritis virus(TGEV)is one of the main pathogens causing severe diarrhea of *** pathogenesis of TGEV is closely related to intestinal ***-trans retinoic acid(ATRA)is the main active metabolite of vitamin A,which has immunomodulatory and anti-inflammatory ***,it is unclear whether ATRA can alleviate TGEV-induced intestinal inflammation and barrier dysfunction in *** study aimed to investigate the effects of ATRA on growth performance,diarrhea,intestinal inflammation and intesti-nal barrier integrity of TGEV-challenged *** In a 19-d study,32 weaned piglets were randomly divided into 4 treatments:Control group(basal diet),TGEV group(basal diet+TGEV challenge),TGEV+ATRA5 group(basal diet+5 mg/d ATRA+TGEV challenge)and TGEV+ATRA15 group(basal diet+15 mg/d ATRA+TGEV challenge).On d 14,piglets were orally administered TGEV or the sterile *** Feeding piglets with 5 and 15 mg/d ATRA alleviated the growth inhibition and diarrhea induced by TGEV(P<0.05).Feeding piglets with 5 and 15 mg/d ATRA also inhibited the increase of serum diamine oxidase(DAO)activ-ity and the decrease of occludin and claudin-1 protein levels in jejunal mucosa induced by TGEV,and maintained intestinal barrier integrity(P<0.05).Meanwhile,5 mg/d ATRA feeding increased the sucrase activity and the expres-sions of nutrient transporter related genes(GLUT2 and SLC7A1)in jejunal mucosa of TGEV-challenged piglets(P<0.05).Furthermore,5 mg/d ATRA feeding attenuated TGEV-induced intestinal inflammatory response by inhibit-ing the release of interleukin(IL)-1β,IL-8 and tumor necrosis factor-α(TNF-α),and promoting the secretion of IL-10 and secretory immunoglobulin A(sIgA)(P<0.05).Feeding 5 mg/d ATRA also down-regulated the expressions of Toll-like receptors and RIG-I like receptors signaling pathway related genes(TLR3,TLR4,RIG-I,MyD88,TRIF and MAVS)and the phosphorylation level of nuclear factor-κB-p65(NF-κB p65),and

关键词： All-trans retinoic acid Inflammation Intestinal barrier Piglets Transmissible gastroenteritis virus

Along-track Calibration of the Zhurong Rover Magnetometer

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Science China Earth Sciences 2024年第2期67卷 552-565页

作者： Hao luo aimin DU Yasong GE Ying ZHANG Haiying LI Lin TIAN Kuixiang ZHANG Shuquan SUN Lin ZHAO Zhi LI Xiao FENG CAS Engineering Laboratory for Deep Resources Equipment and Technology Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China College of Earth Science University of Chinese Academy of SciencesBeijing100049China National Astronomical Observatories Chinese Academy of SciencesBeijing100101China

As part of the Chinese Tianwen-1 mission,the Zhurong Rover began its scientific investigation in the southern Utopia Planitia after its successful landing in 15 May,*** Zhurong Rover magnetometer(RoMAG),one of the six payloads onboard the rover,includes two identical high-sensitivity triaxial fluxgate magnetometers and can implement mobile magnetic measurements on the surface of *** a rover magnetic compensation procedure was conducted to remove the magnetic interferences pre-launch,due to the different state of the payloads and electric power system such as the solar panel,an along-track calibration of the magnetometer is necessary to obtain a more accurate Martian magnetic *** methods,mast yaw rotations and Rover yaw rotations were utilized separately to determine the Martian horizontal magnetic *** show that the Martian horizontal magnetic components determined by the two methods are in good agreement,with the root mean square deviation less than 2.0 *** vertical component was also constrained through the pitch movements of the mast by assuming the interferences field distributes like a dipole field.A linear correlation between magnetic field measurements and the solar array currents was derived to calibrate the body field during the regular *** conclude that more accurate measurements could be made when applying the calibration results in the magnetic survey on the surface of Mars.

关键词： The Zhurong Rover Magnetometer Along-track calibration Remnant magnetization

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基于元模型的军事信息系统体系结构建模方法

国防科技大学学报 2012年第1期34卷 82-87页

作者：谢文才罗雪山罗爱民国防科技大学信息系统工程重点实验室湖南长沙410073

为了实现不同体系结构框架方法论及体系结构工具下所开发体系结构的可理解、可比较、可交换,促进体系结构数据的共享和重用,提出了基于元模型的军事信息系统体系结构建模方法;以模型驱动体系结构(MDA)思想为基础,研究了体系结构元模型... 详细信息

为了实现不同体系结构框架方法论及体系结构工具下所开发体系结构的可理解、可比较、可交换,促进体系结构数据的共享和重用,提出了基于元模型的军事信息系统体系结构建模方法;以模型驱动体系结构(MDA)思想为基础,研究了体系结构元模型到支持体系结构建模语言的转换方法;设计了元模型规范下的体系结构建模的实现方法;以作战规则模型(OV-6a)的IDEF0建模为例分析了转换方法所涉及核心规则的具体实现,说明了该方法的可行性和有效性。

关键词：体系结构体系结构建模元模型可扩展标记语言