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Cavernous nerve reconstruction with autologous vein graft and platelet-derived growth factors

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Asian Journal of Andrology 2017年第3期19卷 298-302页

作者： Xie-Gang Ding shi-Wen Li Xin-min Zheng Xing-Huan Wang Yi luo Department of Urology Zhongnan Hospital Wuhan University Wuhan 430071 China.

In this study, we investigated the feasibility of using autologous vein graft and platelet-derived growth factors to bridge transected cavernous nerve in a rat model. A short defect in the bilateral cavernous nerve was created and repaired with vein graft from the right jugular vein or vein graft plus platelet-derived growth factors. The 32 rats were divided into four groups, namely Group 1 - no repair as a negative control, Group 2 - vein graft alone, Group 3 - vein graft plus platelet-derived growth factors, and Group 4 - sham operation as a positive control. We evaluated nerve regeneration and functional recovery using retrograde tracing study with FluoroGold, Toluidine blue staining of cavernous nerve, and the intracavernous pressure at 3 months. Three months after surgery, rich FluoroGold-positive cells were observed in the sham and vein graft plus platelet-derived growth factors group, but very few were found in the no repair group. The number of myelinated axons of regenerated cavernous nerve and intracavernous pressure were increased obviously in the two vein graft groups, especially in the vein graft plus platelet-derived growth factors group. These findings confirm the feasibility of using autologous vein as guides for cavernous nerve regeneration, and the regeneration can be further enhanced when the vein is filled with Dlatelet-derived growth factors.

关键词： cavernous nerve nerve regeneration platetet-rich plasma vein graft

Concise extraction and characterization of the pore-throat network in unconventional hydrocarbon reservoirs: A new perspective

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Petroleum Science 2024年第3期21卷 1474-1487页

作者： Shu-Heng Du Yong-min shi State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Engineering Science University of Chinese Academy of SciencesBeijing100049China School of Earth and Space Sciences Peking UniversityBeijing100871China

In this study,a new image-based method for the extraction and characterization of pore-throat network for unconventional hydrocarbon storage and exploitation is proposed.“Pore-throat solidity”,which is analogous to particle solidity,and a new method for automatic identification of pores and throats in tight sandstone oil reservoirs are ***,the“pore-throat combination”and“pure pore”are defined and distinguished by drawing the cumulative probability curve of the pore-throat solidity and by selecting an appropriate cutoff *** the discrete grid set is recognized as a pore-throat combination,Legendre ellipse fitting and minimum Feret diameter are *** the pore and throat grid sets are identified as pure pores,the pore diameter can be directly *** the new method,the analytical results for the physical parameters and pore radius agree well with most prior *** results comparing the maximum ball and the new model could also prove the accuracy of the latter's in micro and nano *** new model provides a more practical theoretical basis and a new calculation method for the rapid and accurate evaluation of the complex processes of oil migration.

关键词： Hydrocarbon exploitation Pore Throat Porous media Identification

Further evidence for paternal DNA transmission in gynogenetic grass carp

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Science China(Life Sciences) 2020年第9期63卷 1287-1296页

作者： Zhuangwen Mao Yeqing Fu shi Wang Yude Wang Kaikun luo Chun Zhang min Tao Shaojun Liu State Key Laboratory of Developmental Biology of Freshwater Fish Hunan Normal UniversityChangsha 410081China College of Life Sciences Hunan Normal UniversityChangsha 410081China College of Chemistry and Chemical Engineering Hunan Normal UniversityChangsha 410081China

Gynogenesis is an important breeding method in aquaculture and has been widely applied to many fish *** gynogenetic progenies are to inherit paternal partial genomic DNA,this will increase genetic variation and will provide a useful outcome for *** this study,we investigated the genetic variation in homeobox(Hox)gene clusters(Hox A4 a,Hox A9 a,Hox A11 b,Hox B1 b,Hox C4 a,Hox C6 b,and Hox D10 a)among koi carp(Cyprinus carpio haematopterus,KOC;the stimulation sperm source),grass carp(Ctenopharyngodon idellus),and gynogenetic grass carp(GGC).We found paternal DNA(a special DNA fragment and Hox C6 b)derived from KOC and a recombinant gene belonging to Hox C6 b in *** are the first to report the recombinant Hox C6 b in *** study provides further evidence for paternal DNA transmission to gynogenetic progenies,which is a finding with great significance for the genetic breeding of fish.

关键词： Ctenopharyngodon idellus Cyprinus carpio haematopterus gynogenesis Hox genes DNA fragment recombinant gene

Asymmetric Reactions Catalyzed by Chiral Tertiary Phosphines

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Chinese Journal of Chemistry 2020年第11期38卷 1395-1421页

作者： Yin Wei min shi State Key Laboratory of Organometallic Chemistry Center for Excellence in Molecular SynthesisUniversity of Chinese Academy of SciencesShanghai Institute of Organic ChemistryChinese Academy of Sciences345 Ling ling RoadShanghai 200032China

Chiral tertiary phosphines are versatile Lewis base catalysts capable of promoting a wide range of asymmetric *** particular,the recent designed chiral phosphines based on the concept of bi-/multifunctionality have been demonstrated to be effective catalysts for many types of asymmetric reactions such as(aza)-MBH reaction/RC reaction,cycloaddition reaction,domino reaction,nucleophilic addition reaction,*** review summarizes the recent advances in this field and highlights the selected significant achievements.

关键词： Chiral asymmetric versatile

Effect of Bi/Si Ratio of BiBSi Glass on Its Structure,Properties and Laser Sealing Shear Strength for Vacuum Glazing

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期 13-24页

作者：刘伟 JIAO Jinxu luo Dusha ZHOU Junjie shi Lifen WANG Weiwei LI Changqing WANG Peng XIONG Dehua 李宏 State Key Laboratory of Silicate Materials for Architectures Wuhan University of Technology Silica-Based Materials Laboratory of Anhui Province CNBM Research Institute for Advanced Glass Materials Group Co. Ltd State Key Laboratory of Advanced Technology for Float Glass CNBM Research Institute for Advanced Glass Materials Group Co. Ltd

The low-melting glass of Bi2O3-B2O3-SiO2（BiBSi） system was used for the first time for laser sealing of vacuum *** the condition of constant boron content,how the structure and properties vary with Bi/Si ratio in low-melting glass was *** addition,the relationships between laser power,low-melting glass solder with different Bi/Si ratios and laser sealing shear strength were *** results show that a decrease in the Bi/Si ratio can cause a contraction of the glass network of the low-melting glass,leading to an increase of its characteristic temperature and a decrease of its coefficient of thermal *** laser sealing,the copper ions in the low-melting glass play an endothermic role.A change in the Bi/Si ratio will affect the valence state transition of the copper ions in the low-melting *** absorbance of the low-melting glass does not follow the expected correlation with the Bi/Si ratio,but shows a linear correlation with the content of divalent copper *** greater the concentration of divalent copper ions,the greater the absorbance of the low-melting glass,and the lower the laser power required for laser *** shear strength of the low melting glass solder after laser sealing was tested,and it was found that the maximum shear strength of Z1 glass sample was the highest up to 2.67 MPa.

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An improvement of Chen-Ru-Yan's degenerated second main theorem

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Science China Mathematics 2015年第12期58卷 2517-2530页

作者： shi Lei RU min Department of Mathematics East China Normal University Department of Mathematics University of Houston

We give an improvement for the second main theorem of algebraically non-degenerate holomorphic curves into a complex projective variety V intersecting hypersurfaces in subgeneral position, obtained by Chen et al.(2012... 详细信息

关键词： Nevanlinna theory holomorphic curve second main theorem truncation level

Effects of process parameters and annealing on microstructure and properties of CoCrFeMnNi high-entropy alloy coating prepared by plasma cladding

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China Foundry 2023年第6期20卷 491-502页

作者： shi-yong Wei Chao-min Wang Wen-yi Peng Ru-kai luo Yun Chen Zhen-zhen Wan Yin Jin Institute of Applied Physics Jiangxi Academy of SciencesNanchang 330090China Materials Science and Engineering School Nanchang UniversityNanchang 330029China

Plasma cladding was used to prepare a CoCrFeMnNi high-entropy alloy(HEA)coating under different *** process parameters were optimized using an orthogonal experiment design based on surface morphology quality characteristics,dilution rate,and *** optimal process parameters were determined through range and variance analysis to be a cladding current of 70 A,a cladding speed of 7 cm·min^(-1),and a powder gas flow rate of 8 L·s^(-1).During the optimized experiments,both the cladded and annealed CoCrFeMnNi HEA coatings exhibit some pores,micro-voids,and a small amount of ***,the aggregation in the annealed coating is more dispersed than that in the cladded *** cladded CoCrFeMnNi HEA coating consists of simple FCC phases,while a new Cr-rich phase precipitates from the FCC matrix after annealing the coating at a temperature range of 550℃-950℃.After annealing at 850℃,the proportion of the FCC phase decreases compared to the cladded coating,and the number of large-angle grain boundaries is significantly ***,the proportion of grains with sizes below 50μm increases from 61.7%to 74.3%.The micro-hardness and wear resistance of the cladded coating initially increases but then decreases with an increase in annealing temperature,indicating that appropriate annealing can significantly improve the mechanical properties of the CoCrFeMnNi HEA coatings by plasma *** micro-hardness of the CoCrFeMnNi HEA coatings after annealing at 650℃ increases to 274.82 HV_(0.2),while the friction coefficient decreases to below 0.595.

关键词： plasma cladding CoCrFeMnNi HEA coating process optimization annealing microstructure and mechanical property

Considerations on the concept, definition, and diagnosis of amyotrophic lateral sclerosis

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Neural Regeneration Research 2021年第9期16卷 1723-1729页

作者： Ren-shi Xu min Yuan Department of Neurology Jiangxi provincial People’s HospitalAffiliated People’s Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina

The concept, definition, and diagnosis of amyotrophic lateral sclerosis(ALS) currently present some problems. This article systematically reviews the literature on the history, current concepts, definition, and diagnosis of ALS, and discloses the present problems based on the retrieved literature and the authors' clinical experience. The current concepts and definitions of ALS have not yet been unified or standardized in clinical practice, and are sometimes vague or inaccurate, which can cause difficulties for neurologists in the clinical treatment of ALS. The concept and definition of ALS need to be further ascertained, and the current diagnostic criteria for ALS require further development. The identification of effective and objective biomarkers may be a feasible method for the early and accurate diagnosis of ALS. Therefore, future research should focus on the identification of reliable biomarkers—especially neuroimaging biomarkers—through autopsy. Standardizing the concept and definition of ALS and formulating clear diagnostic criteria will largely avoid many uncertainties in the future clinical research and treatment of ALS, which will greatly benefit patients.

关键词： amyotrophic lateral sclerosis clinical symptoms concept definition diagnosis familial amyotrophic lateral sclerosis motor neuron disease muscle atrophy

Statistical inference for dependence competing risks model under middle censoring

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Journal of Systems Engineering and Electronics 2019年第1期30卷 209-222页

作者： WANG Yan shi Yimin WU min Department of Applied Mathematics Northwestern Polytechnical University School of Science Xi'an Polytechnic University School of Economics & Management Shanghai Maritime University

Middle censoring is an important censoring scheme,in which the actual failure data of an observation becomes unobservable if it falls into a random interval. This paper considers the statistical analysis of the dependent competing risks model by using the Marshall-Olkin bivariate Weibull(MOBW) *** maximum likelihood estimations(MLEs), midpoint approximation(MPA) estimations and approximate confidence intervals(ACIs) of the unknown parameters are obtained. In addition, the Bayes approach is also considered based on the Gamma-Dirichlet prior of the scale parameters, with the given shape *** acceptance-rejection sampling method is used to obtain the Bayes estimations and construct credible intervals(CIs). Finally,two numerical examples are used to show the performance of the proposed methods.

关键词： middle censoring dependent competing risks model Marshall-Olkin bivariate Weibull (MOBW) distribution acceptancerejection sampling.