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Improved hand tracking algorithm in video sequences for intelligent rehabilitation

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重庆邮电大学学报（自然科学版） 2009年第2期21卷 142-147页

作者： LI Ling luo yuan ZHANG Yi ZHANG Bai-sheng Research Center of Intelligent System and Robotics Chongqing University of Posts and Telecommunications Chongqing 400065 P. R. China

Intelligent rehabilitation system is an active research *** is motivated by the increased number of limb disabled *** motion tracking is the key technology of intelligent rehabilitation system,because the movement of limb disabled patients needs to be localized and learned so that any undesired motion behavior can be corrected in order to reach an *** paper introduces a real-time tracking system of human hand motion,specifically intent to be used for home *** sensor(camera)is employed in this system to track the hand movement,and the improved Camshift algorithm and Kalman filter are used to implement dynamic hand tracking in the *** algorithm is able to track any kind of target colors by building a histogram distribution of the H channel in HSV color space from the region of interests selected by users at the initial *** filter is able to predict hand location in one image frame based on its location data detected in the previous *** experimental results show that this system can track 2D hand motion and has acceptable accuracy by using the two algorithms *** new algorithm proposed in this paper can not only deal with the skin color interference problems,but also deal well with the track of complex background.

关键词：跟踪算法视频序列康复智能人体运动跟踪 CAMSHIFT算法实时跟踪系统 HSV颜色空间

Global trends and knowledge-relationship of symptom clusters in cancer research:a bibliometric analysis over the past 20 years

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Frontiers of Nursing 2023年第3期10卷 273-288页

作者： Ran An yuan luo Wen-Feng Chen Muhammad Sohaib Mei-Zi Liu Xiangya School of Nursing Central South UniversityChangshaHunan 410013China Teaching and Research Section of Clinical Nursing Xiangya Hospital Central South UniversityChangshaHunan 410013China Children Hospital and Institute of Child Health Multan 60000Pakistan

Objective:To use Cite Space and VOSviewer to investigate the scientific production in the field of symptom clusters in cancer ***:The search was performed using the terms“symptom clusters,”“cancer,”and“oncology”on the Web of Science Core Collection *** retrieval time was from 2001 to 2021,which covers the last 2 *** on the production theory of scientific knowledge and the data mining of citations,data pertaining to the annual publications,journals,countries,organizations,authors,and keywords that produce symptom clusters in cancer research,as well as their cooperation(collaboration network),were extracted,and then both were clarified by the software tools VOSviewer(version 1.6.16)and Cite Space(version 6.1.R2).Results:A total of 1796 publications were retrieved between 2001 and 2021,and 473 relevant publications were included after *** results showed an increasing trend in published *** United States had the largest number of publications(261/473,55.18%),followed by China and *** University of California,San Francisco,was the most productive *** research hotspots included the analysis of symptom clusters and symptom management in patients with breast cancer and lung cancer,as well as any advanced cancer and cancer cachexia;fatigue-related symptom clusters and depression-anxiety symptom cluster;and the impacts of symptom clusters on quality of *** research frontiers included analysis between health-related quality of life and symptom clusters,data mining in symptom clusters,research on the mental health status of cancer patients,and study of the mechanism and biological pathways of symptom ***:The study provides insight into the global research perspective for the scientific progress on cancer symptom clusters,which suggests a growing scientific interest in this field,and more studies are warranted to guide symptom management.

关键词： bibliometrics cancer Citespace symptom clusters systematic review VOSviewer

TRPV4 Regulates Soman-Induced Status Epilepticus and Secondary Brain Injury via NMDA Receptor and NLRP3 Inflammasome

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Neuroscience Bulletin 2021年第7期37卷 905-920页

作者： Shuai Wang Huanhuan He Jianhai Long Xin Sui Jun Yang Guodong Lin Qian Wang Yongan Wang yuan luo State Key Laboratory of Toxicology and Medical Countermeasures Institute of Pharmacology and ToxicologyAcademy of Military Medical SciencesBeijing 100850China

Nerve agents are used in civil wars and terrorist attacks,posing a threat to public *** exposure to nerve agents such as soman(GD)causes serious brain damage,leading to death due to intense seizures induced by acetylcholinesterase inhibition and neuronal injury resulting from increased excitatory amino-acid levels and ***,data on the anticonvulsant and neuroprotective efficacies of currently-used countermeasures are ***,we evaluated the potential effects of transient receptor vanilloid 4(TRPV4)in the treatment of soman-induced status epilepticus(SE)and secondary brain *** demonstrated that TRPV4 expression was markedly up-regulated in rat hippocampus after soman-induced *** of the TRPV4 antagonist GSK2193874 prior to soman exposure significantly decreased the mortality rate in rats and reduced SE ***4-knockout mice also showed lower incidence of seizures and higher survival rates than wild-type mice following soman *** in vivo and in vitro experiments demonstrated that blocking TRPV4 prevented NMDA receptor-mediated glutamate *** protein levels of the NLRP3 inflammasome complex and its downstream cytokines IL-1βand IL-18 increased in soman-exposed rat ***,TRPV4 inhibition or deletion markedly reversed the activation of the NLRP3 inflammasome *** conclusion,our study suggests that the blockade of TRPV4 protects against soman exposure and reduces brain injury following SE by decreasing NMDA receptor-mediated excitotoxicity and NLRP3-mediated *** our knowledge,this is the first study regarding the“dual-switch”function of TRPV4 in the treatment of soman intoxication.

关键词： Nerve agents Soman TRPV4 NMDA receptor NLRP3 inflammasome

Obstetrical Disease Spectrum in China： An Epidemiological Study of 111,767 Cases in 2011

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Chinese Medical Journal 2015年第9期128卷 1137-1146页

作者： Xiao-Lin luo Wei-yuan Zhang Department of Obstetrics Beijing Obstetrics and Gynecology Hospital Capital Medical University Beijing 100026 China

Background：No national research on maternal and fetal complications and outcomes has been carried out in the mainland of China in recent *** study was to provide a scientific basis for better control of obstetrical and neonatal diseases and better allocation of medical resources by analyzing the epidemiological characteristics of obstetrical diseases in the mainland of ***：Hospitalized obstetrical cases from 19 tertiary and 20 secondary hospitals in 14 provinces （nationally representative） during the period January 1,2011 to December 31,2011 were randomly *** general condition,pregnancy complications,and perinatal outcomes of the patients were ***：The top five medical and surgical complications of pregnant women in the mainland of China were anemia （6.34％）,uterine fibroids （2.69％）,thyroid disease （1.11％）,thrombocytopenia （0.59％）,and heart disease （0.59％）.The incidences of premature rupture of membranes （PROM）,preterm birth,prolonged pregnancy,hypertensive disorders complicating pregnancy （HDCP）,multiple pregnancy,intrahepatic cholestasis of pregnancy （ICP）,placenta previa,placental abruption,postpartum hemorrhage,and amniotic fluid embolism were 15.27％,7.04％,6.71％,5.35％,1.57％,1.22％,1.14％,0.54％,3.26％ and 0.06％,*** incidences of anemia and prolonged pregnancy were significantly lower in tertiary than secondary hospitals （P ＜ 0.001）,whereas the incidence of uterine fibroids,thyroid diseases,thrombocytopenia,heart disease,PROM,preterm birth,HDCP,multiple pregnancy,ICP,placenta previa,and placental abruption were significantly higher in tertiary than secondary hospitals （P ＜ 0.001）.The cesarean section （CS） rate was 54.77％.The newborn sex ratio was 119：100,and 1.03％ of the neonates were *** percentages of low birth weight and fetal macrosomia in full-term babies were 2.10％ and 7.09％,***：The incidence of some obstetrical diseases is still high in the mainland of *** CS rate is much hig

关键词： Disease Spectrum Perinatal Outcomes Pregnancy Complications

Mitogen activated protein kinase signaling pathways participate in the active principle region of Buyang Huanwu decoction-induced differentiation of bone marrow mesenchymal stem cells

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Neural Regeneration Research 2012年第18期7卷 1370-1377页

作者： Jinghui Zheng Jian Liang Xin Deng Xiaofeng Chen Fasheng Wu Xiaofang Zhao yuan luo Lei Fu Zuling Jiang Ruikang Hospital Attached to Guangxi Traditional Chinese Medicine College Level-3 Laboratory of Cell Molecular Biology of StateAdministration of Traditional Chinese Medicine of the People's Republic of ChinaNanning 530011Guangxi Zhuang Autonomous Region China

Our preliminary studies confirmed that an active principle region of Buyang Huanwu decoction, comprising alkaloid, polysaccharide, aglycon, glucoside and volatile oil, can induce bone marrow mesenchymal stem cell differentiation into neurons. Mitogen-activated protein kinase signaling was identified as one of the key pathways underlying this differentiation process. The present study shows phosphorylated extracellular signal-regulated protein kinase and phosphorylated p38 protein expression was increased after differentiation. Cellular signaling pathway blocking agents, PD98059 and SB203580, inhibited extracellular signal-regulated protein kinase and p38 in mitogen-activated protein kinase signaling pathways respectively, mRNA and protein expression of the neuronal marker, neuron specific enolase, and neural stem cell marker, nestin, were decreased in bone marrow mesenchymal stem cells after treatment with the active principle region of Buyang Huanwu decoction. Experimental findings indicate that, extracellular signal-regulated protein kinase and p38 in mitogen-activated protein kinase signaling pathways participate in bone marrow mesenchymal stem cell differentiation into neuron-like cells, induced by the active principle region of Buyang Huanwu decoction.

关键词： Buyang Huanwu decoction bone marrow mesenchymal stem ceils extracellular signal-regulatedprotein kinase mitogen-activated protein kinase signaling pathway neuron specific enolase nestin cell signal transduction pathway neural regeneration

Case Study of Low-carbon Rural Residences and Building Materials

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Journal of Landscape Research 2012年第10期4卷 1-4页

作者： luo yuan School of Design and Art Chongqing Technology and Business University

Driven by the policy of "balancing urban and rural development", urbanization in China has been accelerated and agricultural population transferred to urban areas, which guarantees the improvement of life quality and living environment of rural and agricultural population. The urbanization has always been accompanied by national economic development and social progress, relocation and development of rural areas have become a social issue for a certain time. Therefore, it is imperative to explore a series of concrete, well-timed and practical measures for settling rural population, figure out proper modes, materials and methods for rural residence planning and construction under the new conditions, and provide relevant operation and theoretical support. Problems in mountainous rural areas of China were proposed as great population but limited land resources, backward construction techniques, and residences not valuing low carbon or environment protection. In view of these problems, construction techniques suitable for actual conditions of rural areas were explored, energy-saving building materials combined, the style of "dragon sucking water" for mountainous rural areas was proposed, design advantages and details of this architectural model were analyzed.

关键词： New countryside Residence Low carbon Materials

Indoor monocular mobile robot navigation based on color landmarks

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重庆邮电大学学报（自然科学版） 2009年第2期21卷 162-165页

作者： luo yuan ZHANG Bai-sheng ZHANG Yi LI Ling Research Center of Intelligent System and Robotics Chongqing University of Posts and Telecommunications Chongqing 400065 P. R. China

A robot landmark navigation system based on monocular camera was researched theoretically and *** the landmark setting and its data structure in programming was given;then the coordinates of them getting by robot and global localization of the robot was described;finally experiments based on Pioneer III mobile robot show that this system can work well at different topographic situation without lose of signposts.

关键词：移动机器人导航系统彩色标志室内数据结构全球定位基础里程

Analysis of the tea packaging design psychologies

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International English Education Research 2016年第2期 23-24页

作者： luo yuan Canvard College of Beijing Technology and Business University Beijing 101118

The tea packing design occupies the important position in the field of the graphic design. A successful tea packing design can affect the consumers＇ desire to buy. In this article, from the tea packaging colors, forms, shapes and so on, the author discusses the vision, touch, taste and other sensory stimulation, and analyzes the relationship between the constituent elements including the emotional factors and the psychological needs of the consumers, as well as the packaging design.

关键词： Tea packaging emotional needs design psychology

Establishment of a cholangiocarcinoma risk evaluation model based on mucin expression levels

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1344-1360页

作者： Chun-yuan Yang Li-Mei Guo Yang Li Guang-Xi Wang Xiao-Wei Tang Qiu-Lu Zhang Ling-Fu Zhang Jian-yuan luo Department of Pathology Institute of Systems BiomedicineSchool of Basic Medical Sciences Peking UniversityPeking University Third HospitalPeking University Health Science CenterBeijing 100191China Department of General Surgery Peking University Third HospitalBeijing 100191China Department of Medical Genetics Department of Biochemistry and BiophysicsSchool of Basic Medical Sciences Peking UniversityPeking University Health Science CenterBeijing 100191China

BACKGROUND Cholangiocarcinoma(CCA)is a highly malignant cancer,characterized by frequent mucin ***1 has been identified as a critical oncogene in the progression of ***,the comprehensive understanding of how the mucin family influences CCA progression and prognosis is still *** To investigate the functions of mucins on the progression of CCA and to establish a risk evaluation formula for stratifying CCA *** Single-cell RNA sequencing data from 14 CCA samples were employed for elucidating the roles of mucins,complemented by bioinformatic ***-quent validations were conducted through spatial transcriptomics and *** construction of a risk evaluation model utilized the least absolute shrinkage and selection operator regression algorithm,which was further confirmed by independent cohorts and diverse data *** CCA tumor cells with elevated levels of MUC1 and MUC4 showed activated nucleotide metabolic pathways and increased ***5AC-high cells were found to promote CCA progression through WNT ***5B-high cells exhibited robust cellular oxidation activities,leading to resistance against antitumoral ***13-high cells were observed to secret chemokines,recruiting and transforming macrophages into the M2-polarized state,thereby suppressing antitumor ***16-high cells were found to promote tumor progression through interleukin-1/nuclear factor kappa-light-chain-enhancer of activated B cells signaling upon interaction with *** the expression levels of these mucins,a risk factor evaluation formula for CCA was developed and validated across multiple *** samples with higher risk factors exhibited stronger metastatic potential,chemotherapy resistance,and poorer *** Our study elucidates the functional mechanisms through which mucins contribute to CCA development,and provides tools for risk stratification in CCA.

关键词： Mucin Cholangiocarcinoma Single-cell RNA sequencing Spatial transcriptomics Prognosis