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Asian Journal of Andrology 2010年第4期12卷 605-606页

作者： Wen-Hong lu yi-qun Gu National Research Institute for Family Planning Beijing 100081 China

We are very glad to see that the Asian Journal of Andrology published a Special Issue on Semen Analysis in 21st Century Medicine, which well revealed some behind-the-scene controversies of the 5th edition of the WHO laboratory manual for the examination and processing of human semen [1]. Three articles from the special issue, two on the reference values of semen parameters [2, 3] and another presenting the investigation results of 118 laboratories performing semen analysis in China's Mainland [4], are very thoughtprovoking and we would like to share some of our views on these topics.

关键词： WHO laboratory examination semen

Macroscopic Quantum Superposition States in a Model of Photon-Supersonic Phonon Interaction

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Chinese Physics Letters 2000年第7期17卷 504-506页

作者： CHAI JIN-HUA WANG Yan-Bang lu yi-qun Anhui Institute of Optics and Fine Mechanics Chinese Academy of SciencesHefei 230031 Institute of Physics Chinese Academy of SciencesBeijing 100080

A model of photon-hypersonic phonon interaction is proposed. The evolution of macroscopic quantum superpo sition states is analyzed, including the wave function and number distribution. It is shown that a superpositio... 详细信息

关键词： phonon superposition quantum

Polyelectrolytes of Inorganic Polyoxometalates:Prospecting New Charged Polymers for Advanced Applications

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Chinese Journal of Polymer Science 2024年第9期42卷 1254-1269,I0005页

作者： De-yin Wang Zhuo-qun lu Wei Wang College of Medical Linyi UniversityLinyi276000China Center for Synthetic Soft Materials Key Laboratory of Functional Polymer Materials of the Ministry of EducationInstitute of Polymer ChemistryNankai UniversityTianjin300071China

Polyelectrolytes are charged polymers comprising macromolecules in which substantial portions of the constituent units contain cationic(e.g.,pyridinium,ammonium)or anionic(e.g.,sulfonate,carboxylate)groups,which possess special functions from the features of counterions,such as dissociation to charged species,mechanical stability,phase behavior,***,functional polyelectrolytes have been widely applied in many *** this perspective,we present some progresses in the studies of poly(polyoxometalate)s,denoted as poly(POM)s,as a kind of new charged polymers/polyelectrolytes,by covalent bonding between the inorganic polyoxometalate(POM)clusters and the organic polymer *** to the distinct positions of POMs in polymer chain and functions of poly(POM)s,they are divided into the following four categories:crosslinked poly(POM);side-chain poly(POM);backbone poly(POM),including poly(POM)-conjugated polymer hybrid and block poly(POM)-polymer;and POM-based covalent organic framework(PCOF).This perspective introduces the synthesis methods of poly(POM)polyelectrolytes and their macromolecular and aggregate structural characteristics,while also focusing on their properties and *** application areas include catalysis,thermal resistance,optical functions,fuel cells and batteries,etc.

关键词： Charged polymer Polyelectrolyte Polyoxometalate Poly(polyoxometalate) Covalent organic framework

Procyanidin A_1 and its digestive products alleviate acrylamide-induced IPEC-J2 cell damage through regulating Keap1/Nrf2 pathway

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Food Science and Human Wellness 2024年第3期13卷 1475-1484页

作者： Fangfang Yan qun lu Chengming Wang Rui Liu College of Food Science and Technology Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Environment Correlative Dietology(Huazhong Agricultural University) Ministry of EducationWuhan 430070China Key Laboratory of Urban Agriculture in Central China Ministry of Agriculture and Rural AffairsWuhan 430070China

Our previous study has revealed that procyanidin A_(1)(A_(1))and its simulated digestive product(D-A,)can alleviate acrylamide(ACR)-induced intestine cell ***,the underlying mechanism remains *** this study,we elucidated the molecular mechanism for and D-A_(1) to alleviate ACR-stimulated IPEC-J2 cell *** slightly activated nuclear factor erythroid 2-related factor 2(Nrf2)signaling and its target genes,but this activation could not reduce intestine cell damage.A_(1) and D-A_(1) could alleviate ACR-induced cell damage,but the effect was abrogated in cells transiently transfected with Nrf2 small interfering RNA(siRNA).Further investigation confirmed that A_(1) and D-A_(1) interacted with Ketch-like ECH-associated protein 1(Keapl),which boosted the stabilization of Nrf2,subsequently promoted the translocation of Nrf2 into the nucleus,and further increased the expression of antioxidant proteins,thereby inhibiting glutathione(GSH)consumption,maintaining redox balance and eventually alleviating ACR-induced cell ***,there was no difference between A_(1) and D-A_(1) treated groups,indicating that A_(1) can tolerate gastrointestinal digestion and may be a potential compound to limit the toxicity of ACR.

关键词： Procyanidin A_1 Digestive products Acrylamide Nuclear factor erythroid 2-related factor 2(Nrf2) Intestinal cell damage

RFFsNet-SEI:a multidimensional balanced-RFFs deep neural network framework for specific emitter identification

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Journal of Systems Engineering and Electronics 2024年第3期35卷 558-574,F0002页

作者： FAN Rong SI Chengke HAN yi WAN qun School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Institute of Electronic and Electrical Engineering Civil Aviation Flight University of ChinaGuanghan 618307China

Existing specific emitter identification(SEI)methods based on hand-crafted features have drawbacks of losing feature information and involving multiple processing stages,which reduce the identification accuracy of emitters and complicate the procedures of *** this paper,we propose a deep SEI approach via multidimensional feature extraction for radio frequency fingerprints(RFFs),namely,***,we extract multidimensional physical RFFs from the received signal by virtue of variational mode decomposition(VMD)and Hilbert transform(HT).The physical RFFs and I-Q data are formed into the balanced-RFFs,which are then used to train *** introducing model-aided RFFs into neural network,the hybrid-driven scheme including physical features and I-Q data is *** improves physical interpretability of ***,since RFFsNet-SEI identifies individual of emitters from received raw data in end-to-end,it accelerates SEI implementation and simplifies procedures of ***,as the temporal features and spectral features of the received signal are both extracted by RFFsNet-SEI,identification accuracy is ***,we compare RFFsNet-SEI with the counterparts in terms of identification accuracy,computational complexity,and prediction *** results illustrate that the proposed method outperforms the counterparts on the basis of simulation dataset and real dataset collected in the anechoic chamber.

关键词： specific emitter identification(SEI) deep learning(DL) radio frequency fingerprint(RFF) multidimensional feature extraction(MFE) variational mode decomposition(VMD)

Rhodanine derivatives as novel peroxisome proliferator-activated receptor γ agonists

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Acta Pharmacologica Sinica 2007年第12期28卷 2033-2039页

作者： Qing LIU,Yue-yun ZHANG,Hui-li lu,qun-yi LI,Cai-hong ZHOU,Ming-wei WANG~2The National Center,for Drug Screening,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China The National Center for Drug Screening Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai China

Aim:To characterize the in vitro bioactivities of rhodanine derivatives as novelperoxisome proliferator-activated receptor (PPAR)γ modulators,based on a hit(SH00012671) identified during high-throughput screening (HTS) of a diversesynthetic compound library,and to preliminarily elucidate the structure-activityrelationship of this class of PPARγ ***:Full-length PPARγ andretinoid X receptor α(RXRα),biotinylated PPAR response element (PPRE),[~3H]BRL49653 (rosiglitazone),and streptavidin-coated FlashPlate or microbeadswere used to measure the receptor-binding properties of various compounds basedon the scintillation proximity assay (SPA) technology.A recombinant PPRE vec-tor was transiently cotransfected with PPARγ and RXRα plasmids into the Africangreen monkey kidney (CV-1) cells,and the effects of BRL49653 and test com-pounds on transcription mediated by PPARγ were determined by examining lu-ciferase (reporter) responses.3T3-L1 cells were employed to determine whetherthe compounds facilitated adipogenesis upon PPARγ ***:Of the16 000 samples screened with the SPA method,only 1 compound (SH00012671)displayed a similar binding affinity (Ki=186.7 nmol/L) to PPARγ as BRL49653,butit was inactive in the cell-based assays.A series of rhodanine derivatives weresynthesized based on the core structure of SH00012671 and 8 of them showedagonist activities in both cotransfection and pre-adipocyte differentiation *** reduce intrinsic cytotoxicities,the sulphur on the rhodanine was changed *** alteration led to a decrease in receptor-binding affinities while modi-fied analogues generally maintained agonist efficacies in the cell-based *** the analogues studied,compound 31 exhibited about 70% the efficacy exertedby BRL49653 in both cotransfection and pre-adipocyte differentiation ***:Through minor chemical modifications on the core structure of theinitial HTS hit,SH00012671 was transformed to possess both molecular (PPARγ

关键词： rhodanine derivatives peroxisome proliferator-activated receptor structure-activity relationship adipogenesis

Well-dispersed Sb particles embedded on N-doped carbon nanofibers toward high-performance Li-ion battery

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Rare Metals 2024年第7期43卷 2994-3006页

作者： ying Li yi-Han Zhao lu-lu Zhao Peng-Fei Wang ying Xie Ting-Feng yi School of Materials Science and Engineering Northeastern UniversityShenyang 110819China Key Laboratory of Dielectric and Electrolyte Functional Material Hebei Province School of Resources and MaterialsNortheastern University at QinhuangdaoQinhuangdao 066004China Key Laboratory of Functional Inorganic Material Chemistry Ministry of EducationSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080China

The alloy-type material Sb is widely used in the anode materials of lithium-ion batteries(LIBs)due to its high theoretical specific ***,its serious volume expansion problem during alloying/dealloying of Li~+limits its practical *** this work,C-Sb composite was constructed as anode material of LIBs by electrospinning route for the first time,Sb was introduced into the polyacrylonitrile-based hard carbon and coal tar pitch-based soft carbon composite amorphous carbon fiber with a diameter of 300-600 nm,which realized high cycling *** C-Sb-2(the mass ratio of polyacrylonitrile to Sb source is 1:2)electrode displayed charge capacities of 1098.5,930.3,841.7,753.5,643.9 and 545.8 mAh·g^(-1)at 0.1,0.2,0.3,0.5,1 and 2 A·g^(-1),*** when the current density returned to 0.1 A·g^(-1),the charge capacity was 939.3 mAh·g^(-1),revealing good stability and *** introduction of Sb into the amorphous carbon improved its conductivity and addressed the volume expansion issue of high specific capacity Sb during charge/***-situ XRD analysis confirmed the high reversibility of the C-Sb-2 during charging and *** functional theory(DFT)calculations revealed the gradual enhancement of the interface interaction between Sb_(x)Li_(y) and amorphous carbon(AMC)with increasing lithium content,contributing to the anchoring of alloy nanoparticles on the AMC surface and buffering the volume change of the ***,the gradual lithiation of Sb facilitated the electron transfer from Sb_(x)Li_(y) to *** findings hold promise for designing lithium storage materials with exceptional performance,highlighting the potential of C-Sb composites as anode materials for efficient next-generation lithium storage.

关键词： Li-ion battery Metallic Sb Carbon Electrospinning Cycling stability

The current situation of semen analysis in China,based on a survey of 296 laboratories

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Asian Journal of Andrology 2024年第2期26卷 220-221页

作者： Long-Long Fu ying Liu Xiao-Wei Wang Fang Zhou ying Guo Wen-Hong lu yi-qun Gu National Health Commission Key Laboratory of Male Reproductive Health Reproductive Health Research CenterNational Research Institute for Family PlanningBeijing 100081China Institute of Pediatric Research Children's Hospitalof Soochow UniversitySuzhou 215025China

Dear Editor,Semen analysis is a basic test to assess male fertility and is a fundamental test in assisted reproductive *** the first publication of World Health Organization(WHO)Laboratory Manual of Human Semen and Sperm-Cervical Mucus Interaction in 1980,to the publication of the WHO Manual,6th edition in 2021,these 40 years have been recognized as providing a global standard that is widely used in research and clinical laboratories *** WHO Manual,6th edition in Chinese,which we have been authorized by the WHO to translate,will be published soon.

关键词： technology. analysis translate

Detection of onset of agglomeration in a bubbling fluidized bed biomass combustor using reactive Eulerian computational fluid dynamics

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Particuology 2024年第7期90卷 504-515页

作者： Abdullah Tasleem Atta Ullah Fei Li qun yi William Nimmo Syed Sheraz Daood Department of Chemical Engineering Pakistan Institute of Engineering and Applied Sciences(PIEAS)Lehtrar RoadP.O.Nilore45650IslamabadPakistan Institute of Process Engineering Chinese Academy of SciencesBeijing100190China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan430205China Energy Engineering Group Energy 2050Department of Mechanical EngineeringUniversity of SheffieldSheffieldS37RDUnited Kingdom Institute of Energy and Environmental Engineering Faculty of ElectricalEnergy&Environmental EngineeringUniversity of the PunjabQuaid-e-Azam CampusLahorePakistan Energy Engineering Research and Development Centre Faculty of ElectricalEnergy&Environmental EngineeringUniversity of the PunjabQuaid-e-Azam CampusLahorePakistan

The choice of a type of combustion technology to be used for heat or power generation depends on economic,technical,operational and fuel availability *** benefits associated with the evolving market driven by the fluidised bed combustion(FBC)technology cannot be overlooked especially when gauged at 65 GWth of worldwide installed capacity alongside added benefits of handling fuel variation,low pollutant emissions and high combustion *** or biomass waste will continue to have a vital role to play in the future FBC technology-based power *** often contains high levels of inorganic species that can form sticky agglomerates posing a significant risk to boiler operation resulting in unscheduled *** added complexity of the behaviour of the fuel and bed material mix highlights the requirement for simulation models to identify agglomeration to help improve the overall performance and reliability of FBC *** resolve this problem,this research devised a simulation strategy for the detection of agglomeration using the Eulerian–Eulerian *** developed modelling strategy is validated with the experimental data available in literature for two-dimensional simplified geometry of a pilot-scale fluidised bed *** model results were found promising and robust to predict bed defluidisation times and other parameters consistent with the experimental data.

关键词： Fluidized bed combustion Eulerian Models Biomass Agglomeration Defluidisation

Navigating the safe operation of high-voltage cathodes:Challenges and strategies

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Nano Research 2024年第10期17卷 8694-8705页

作者： Yue Sun Changjian Zuo yi-Chun lu Electrochemical Energy and Interfaces Laboratory Department of Mechanical and Automation EngineeringThe Chinese University of Hong KongHong Kong 999077China

Lithium-ion batteries play a crucial role in storing energy for renewable sources and electric vehicles,yet face challenges related to insufficient energy *** the working-voltage of cathodes is promising to boost the energy density of batteries by increasing both the output voltage and capacity of cathode,which however could compromise life cycle and *** review provides a comprehensive summary of essential factors governing pathways of cathode-induced thermal runaway,including electrolyte decomposition,phase transitions,and crosstalk-induced *** and electrolyte modifications aimed at mitigating parasitic reactions and preventing crosstalk were also *** review concludes with insights into the future application of these strategies,providing a comprehensive perspective on the realization of high-energy and safe batteries.

关键词： battery safety high-voltage cathode lithium-ion battery thermal runaway