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南海叠滘墟改造一期,佛山,广东,中国

世界建筑 2024年第8期 88-93页

作者： Atelier cnS lt Architects 竖梁社绿田工作室

叠滘别名双溪,自公元1101年至今已有近千年历史,叠滘因水而生,是西江与北江冲积平原的一部分,“龙船飘移”是每年端午节的必备看点,人们挤满狭窄的巷道,等待龙舟急速转向的一刻。佛山南海叠滘改造项目,以叠滘“水系文化”为引,提取传统... 详细信息

叠滘别名双溪,自公元1101年至今已有近千年历史,叠滘因水而生,是西江与北江冲积平原的一部分,“龙船飘移”是每年端午节的必备看点,人们挤满狭窄的巷道,等待龙舟急速转向的一刻。佛山南海叠滘改造项目,以叠滘“水系文化”为引,提取传统墟市文化,提出了“社区共建导向下的文商结合体验区”的定位来回应在原住民、现代商业活动及保育和传播当地传统文化等方面保持平衡的需求。

关键词：改造项目墟市端午节社区共建现代商业活动原住民文商结合体验区

Liver transplantation as an alternative for the treatment of intrahepatic cholangiocarcinoma: Past, present, and future directions

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Hepatobiliary & Pancreatic Diseases International 2024年第2期23卷 129-138页

作者： Sudha Kodali Ashton A Connor Souhail Thabet Elizabeth w Brombosz R Mark Ghobrial Sherrie and Alan Conover Center for Liver Disease and Transplantation Houston Methodist HospitalHoustonTX 77030USA JC walter Jr Transplant Center Houston Methodist HospitalHoustonTX 77030USA Department of Medicine Weill Cornell Medical CollegeNew YorkNYUSA Department of Surgery Houston Methodist HospitalHoustonTX 77030USA Department of Surgery Weill Cornell Medical CollegeNew YorkNYUSA School of Medicine New Giza UniversityGizaEgypt

Intrahepatic cholangiocarcinoma(iCCA)is a rare biliary tract cancer with high mortality *** resection of the iCCA lesion is the first choice of treatment,with good prognosis after margin-negative ***,only 12%-40% of patients are eligible for resection at presentation due to cirrhosis,portal hypertension,or large tumor *** transplantation(lt)offers margin-negative iCCA extirpation for patients with unresectable ***,iCCA was a contraindication for lt until size-based selection criteria were introduced to identify patients with satisfied post-lt *** studies have shown that tumor biology-based selection can yield high post-lt survival in patients with locally advanced *** selection criterion is the tumor response to neoadjuvant *** with response to neoadjuvant therapy have better outcomes after lt compared with those without tumor response to neoadjuvant *** index that helps predict the treatment outcome is the *** survival outcomes have also opened the door for living donor lt for *** undergoing lt for iCCA now have statistically similar survival rates as patients undergoing *** combination of surgery and locoregional and systemic therapies improves the prognosis of iCCA patients.

关键词： Liver transplantation Cholangiocarcinoma Hepatectomy Transplant oncology Liver neoplasm

Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice

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Genes & Diseases 2024年第4期11卷 149-151页

作者： Dan Yi Hongting Jin william w.Lu Chunxiang Zhang Guozhi Xiao Liping Tonag Di Chen Research Center for Computer-aided Drug Discovery Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China PFaculty of Pharmaceutical Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China The First college of Clinical Medicine Zhejiang Chinese Medical UniversityHangzhouZhejiang 310053China Department of Cardiology Basic Medicine Innovation Centerfor Cardiometabolic Diseases of Ministry of EducationInstitute of Cardiovascular ResearchThe Affiliated HospitalSouthwest Medical UniversityLuzhouSichuan 646000China School of Medicine Southern University of Science and TechnologyShenzhenGuangdong 518055China

In mammals,skeletal bone development begins at hyaline cartilage formation at the early embryonic stage.1Then osteoblasts from the periosteum,which are distributed surrounding the hyaline cartilage,build up compact bone to formdiaphysis and spongy bone known as primary ossification center.1 Next,osteoclasts from the hematopoietic system destroy spongy bone to generate a medullary cavity.

关键词： cartilage skeletal medullary

Effect of anti-fibrosis compound on collagen expression of hepatic cells in experimental liver fibrosis of rats

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world Journal of Gastroenterology 2000年第6期6卷 877-880页

作者： wang lt Zhang B Chen JJ Shanghai TCM Univ Shuguang Hosp Dept Hepatopathy Shanghai 200021 Peoples R China

INTRODUCTIONLiver fibrosis is mainly characterized by theexcessive synthesis and decreased degradation ofextracellular matrix(ECM),especially the synthesisand deposition of *** all kinds of cellsin the liver have part... 详细信息

关键词： liver cirrhosis collagen hepatic stellate cells immunohistochemistry antifibrosis complex prescription rats

STUDIES ON THE SYNTHESIS OF NOVEL ISONUCLEOSIDE FROM D-GLUCOSE

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Chinese Chemical Letters 1995年第8期6卷 655-656页

作者： Yu, Hw Ma, lt Zhang, LH Beijing Med Univ Sch Pharmaceut Sci Beijing 100083 Peoples R China

A novel isonucleoside, 2,5-anhydro-4-(adenine-9-yl-)-L-iditol was synthesized from D-glucose through 9 steps.

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Testing and Modeling of Bituminous Mortar Response

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Journal of wuhan University of Technology(Materials Science) 2010年第4期25卷 637-640页

作者： woldekidan MF Huurman M Mo lt Department of Civil Engineering Delft University of Technology Key Laboratory of Silicate Materials Science and Engineering Wuhan University of Technology

A dynamic shear rheometer （DSR） setup, with a modified test geometry specifically developed for the mortar, was used to conduct time and frequency domain tests. The mortar was composed of a pure bitumen, filler and fine fractions of sand. In the test setup two mounting procedures were compared and the one that delivers better test result repeatability was selected. Test results obtained from frequency domain tests were used to construct a master curve using time-temperature superposition principle （TTS）. Time domain material functions were obtained from the master curve by using frequency-time domain inter-conversion. In this process a series of Kelvin-Voigt element were used. Using material parameters obtained from frequency domain results, creep-recovery tests in time domain were simulated using a Matlab program. Results show a very good agreement with experimentally obtained creep-recovery data.

关键词： DSR mortar response master curve Kelvin-Voigt

Awareness of eye complications and prevalence of retinopathy in the first visit to eye clinic among type 2 diabetic patients

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International Journal of Ophthalmology(English edition) 2011年第5期4卷 519-524页

作者： I Tajunisah PS wong lt Tan P Rokiah SC Reddy Department of Ophthalmology Faculty of MedicineUniversity of Malaya Final Year Medical Students Faculty of MedicineUniversity of Malaya Department of Medicine(Endocrinology unit) Faculty of MedicineUniversity of Malaya Department of Ophthalmology UCSI School of MedicineTerengganu campus

AIM:To assess the awareness of eye complications and the prevalence of retinopathy,in the first visit to eye clinic,among type 2 diabetic patients attending a tertiary medical centre in Kuala Lumpur,***:An investigator-administered questionnaire was given to 137 patients with diabetes undergoing first time eye screening in the eye *** was followed by a detailed fundus examination by a senior ophthalmologist to assess for presence of ***:Almost 86% of respondents were aware of diabetic eye complications,especially in patients who had achieved tertiary educational level(96.3%).The majority of the patients(78.8%) were referred by their physicians and only 20.4% came on their own *** of the patients(43.8%) did not know how frequent they should go for an eye check-up and 72.3% did not know what treatments were *** of understanding on diabetic eye diseases(68.6%) was the main barrier for most patients for not coming for eye screening *** a high level of awareness,only 21.9% had recorded HbA1c level of while 31.4% were under the erroneous assumption of having a good blood sugar control.A total of 29.2% had diabetic retinopathy in their first visit eye ***:In the present study,29.2% of type 2 diabetic patients had retinopathy in their first time eye *** the awareness of diabetic eye complications was high among first time eye screening patients,the appropriate eye care-seeking behavior was comparatively less and should be rectified to prevent the rise of this sight threatening eye disease.

关键词： diabetic retinopathy eye complications awa-reness eye screening

FOUR NEw GLYCOSIDES, LIGUROBUSTOSIDES A, B, C AND D FROM LIGUSTRUM ROBUSTUM

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Chinese Chemical Letters 1996年第4期7卷 341-344页

作者： Tian, J Zhang, HJ Sun, HD Pan, lt Yao, P Chen, DY ACAD SINICA KUNMING INST BOTLAB PHYTOCHEMKUNMING 650204PEOPLES R CHINA GUIZHOU INST TRADIT CHINESE MED GUIYANG 550002PEOPLES R CHINA

Four new glycosides named ligurobustosides A, B, C and D have been isolated from Ligustrum robustum and their structures identified as geraniol 3-O-alpha-L-rhamnopyranosyl-beta-D-glucopyranoside (1), geraniol-O-alpha-L-rhamnopyranosyl-4-cafferoyl-beta-D- glucopyranoside (2), geraniol 3-O-alpha-L-rhamnopyranosyl-4-trans-P-coumaroyl -beta-D-glucopyranoside (3) and geraniol 3-O-alpha-L-rhamnopyranosyl-4-cis P-coumaroyl-beta-D-glucopyranoside (4), respectively.

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Five New Glycosides, Ligurobustosides E, F, I, J and K from Ligustrum Robustum

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Chinese Chemical Letters 1997年第2期8卷 125-128页

作者： Tian, J Zhang, HJ Sun, HD Pan, lt Yao, P Chen, DY KUNMING INST BOT LAB PHYTOCHEMKUNMING 650204PEOPLES R CHINA GUIZHO INST TRADIT CHINESE MED GUIYANG 550002PEOPLES R CHINA

Five new monoterpenoid glycosides named ligurobustosides E (1), F (2), I (3), J (4) and K (5) were isolated from the leaves of Ligustrum robustum. Their structures were established by spectroscopic and chemical methods.

关键词： JASONIA-MONTANA