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表现为生殖器脓皮病的HIV患者实为转移性Crohn病1例

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世界核心医学期刊文摘（皮肤病学分册） 2005年第6期1卷 41-41页

作者： Avilá rez-Ferná zaro-Ochaita es-Izquierdo J.A. Suández R. lp. Longo-Imedio M.I. J.A.avilés-lzquierdo 崔荣 Department of Dermatology Gregorio Maranon University Hospital Madrid Spain

The differential diagnosis of ulcerative genital lesions in patients with high risk sexual habits can be a challenge even for dermatologists. We present the case of a 27- year-old HIV-positive male with a history of recalcitrant genital ulcers. Microbiology studies were negative. A skin biopsy and a sample from a perineal fistula showed granulomatous infiltrates. The patient was treated with prednisone, metronidazole and aminosalicylates, showing complete resolution of the lesions in a few weeks. The clinical picture and histological findings are consistent with the diagnosis of cutaneous metastatic Crohn’ s disease. Although infrequent, metastatic Crohn’s disease should be suspected in cases of recalcitrant ulcerative conditions, even in the absence of intestinal disease.

关键词： Crohn病1 HIV患者脓皮病高危性行为对氨基水杨酸皮肤活检微生物检查顽固性溃疡皮肤科医生鉴别诊断

边缘下皮质(IL)的动态改变以及IL对前边缘皮质(PL)的调控参与大鼠慢性炎症痛

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中国疼痛医学杂志 2024年第7期30卷 158-158页

作者：刘风雨(译) 北京大学神经科学研究所

慢性疼痛是临床的常见病。内侧前额叶皮质(medial prefrontal cortex,mPFC)参与慢性疼痛发病机制。前边缘皮质(prelimbic cortex,PL)是mPFC的一个核心亚区,介导慢性疼痛。边缘下皮质(IL)是mPFC的另一个亚区,也能够调控伤害性反应。神经... 详细信息

慢性疼痛是临床的常见病。内侧前额叶皮质(medial prefrontal cortex,mPFC)参与慢性疼痛发病机制。前边缘皮质(prelimbic cortex,PL)是mPFC的一个核心亚区,介导慢性疼痛。边缘下皮质(IL)是mPFC的另一个亚区,也能够调控伤害性反应。神经解剖学研究表明,IL深层的兴奋性锥体神经元通过支配PL深层的抑制性中间神经元,进而作用到PL局部的锥体神经元上,调控PL的功能。IL、PL以及IL-PL环路如何参与慢性疼痛的发病机制,不甚清晰。研究者采用完全弗氏佐剂(complete Freund's adjuvant,CFA)建立的大鼠慢性炎症痛模型,结合体电生理记录和化学遗传学等方法,深入解析IL、PL及其环路在慢性疼痛中的作用。

关键词：中间神经元完全弗氏佐剂慢性疼痛神经解剖学锥体神经元大鼠发病机制

Voltammetric Studies of the Interaction of Tris (1,10-phenanthroline) Cobalt (III) with Bovine Serum Albumin

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Chinese Chemical Letters 2001年第11期12卷 989-992页

作者： Lu, lp.Jin, BK Anhui Univ Dept Chem Hefei 230039 Peoples R China

The voltammetric methods were used to prove the interaction of metal complex Co(phen)(3)(3+) with bovine serum albumin (BSA). The interaction of BSA with Co(phen)(3)(3+) molecules using BSA-modified electrode is described. Information of the binding ratio and interaction mode can be obtained from their electrochemical behavior and electrochemical data. Furthermore, attenuated total reflection infrared experiment was performed to prove the interaction between complexes and BSA.

关键词： bovine serum albumin nano-gold modified electrode cyclic voltammetry

Photoisomerization of norbornadiene group in a rigid bichromophoric compound initiated by remote keto chromophore: long-distance through-bond triplet energy transfer

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Chinese Journal of Chemistry 1996年第4期14卷 377-380页

作者： Tung, CH Zhang, lp.Li, Y CHINESE ACAD SCI INST PHOTOG CHEMBEIJING 100101PEOPLES R CHINA

A diad compound 3 beta(bicyclo[2,2,1]hepta-2,5-diene-2-methylcarboxylate-3-carboxy)-androst-5-en-17-one (NBD-S-ONE) was synthesized and its photochemistry was examined. Irradiation of NBD-S-ONE in acetonitrile at lambda > 300 nm selectively excited the keto chromophore. After intersystem crossing, the triplet energy of the keto group was transferred to the NBD group with 18.6% efficiency via a through-bond mechanism, resulting in the isomerization of the latter group to the quadricyclane group.

关键词： norbornadiene photoisomerization through-bond triplet energy transfer

自发性疼痛的神经机制--前边缘皮层存在特异性编码自发性疼痛的神经元群体

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中国疼痛医学杂志 2024年第10期30卷 749-749页

作者：刘风雨(译) 北京大学神经科学研究所

自发性疼痛是慢性疼痛病人的重要主诉,但其机制不甚清楚,缺乏有效治疗手段,严重影响病人的生活质量。既往研究发现,持续性的自发疼痛和内侧前额叶的活动相关。该研究目的在于探讨内侧前额叶神经元群体如何编码和调控自发性疼痛行为。主... 详细信息

自发性疼痛是慢性疼痛病人的重要主诉,但其机制不甚清楚,缺乏有效治疗手段,严重影响病人的生活质量。既往研究发现,持续性的自发疼痛和内侧前额叶的活动相关。该研究目的在于探讨内侧前额叶神经元群体如何编码和调控自发性疼痛行为。主要结果:(1)慢性炎症痛模型大鼠出现自发性疼痛行为,表现为舔舐足底和抬足等。

关键词：自发性疼痛模型大鼠慢性疼痛内侧前额叶神经机制特异性持续性治疗手段

Design and dynamic analysis of integrated architecture for vibration energy harvesting including piezoelectric frame and mechanical amplifier

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Applied Mathematics and Mechanics(English Edition) 2021年第6期42卷 755-770页

作者： Xiangjian DUAN Dongxing CAO Xiaoguang lp.Yongjun SHEN Beijing Institute of Structure and Environment Engineering Beijing 100076China Faculty of Materials and Manufacturing Bejing University of TechnologyBeijing 100124China Beijing Key Laboratory of Nonlinear V ibrations and Strength of Mechanical Structures Beijing 100124China State Key Laboratory of Mechanical Behavior and System Safety of Trafic Engineering Structures Shijiazhuang Tiedao UniversityShijiazhuang 050043China

Vibration energy harvesters(VEHs) can transform ambient vibration energy to electricity and have been widely investigated as promising self-powered devices for wireless sensor networks, wearable sensors, and applications of a micro-electro-mechanical system(MEMS). However, the ambient vibration is always too weak to hinder the high energy conversion efficiency. In this paper, the integrated frame composed of piezoelectric beams and mechanical amplifiers is proposed to improve the energy conversion efficiency of a VEH. First, the initial structures of a piezoelectric frame(PF) and an amplification frame(AF) are designed. The dynamic model is then established to analyze the influence of key structural parameters on the mechanical amplification factor. Finite element simulation is conducted to study the energy harvesting performance, where the stiffness characteristics and power output in the cases of series and parallel load resistance are discussed in detail. Furthermore, piezoelectric beams with variable cross-sections are introduced to optimize and improve the energy harvesting efficiency. Advantages of the PF with the AF are illustrated by comparison with conventional piezoelectric cantilever beams. The results show that the proposed integrated VEH has a good mechanical amplification capability and is more suitable for low-frequency vibration conditions.

关键词： vibration energy harvesting mechanical amplifier piezoelectric frame(PF) amplification frame(AF) variable cross-section beam

Alloy Model for the Stacking Fault Energy

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Journal of Materials Science & Technology 1996年第1期12卷 72-74页

作者： Nie, XL Zhou, YM Zhong, lp.Wang, DS Wang, RH Ye, YY WUHAN UNIV DEPT PHYSWUHAN 430072PEOPLES R CHINA WUHAN UNIV CTR INSTRUMENTAL ANALWUHAN 430072PEOPLES R CHINA

An accurate and simple model of stacking fault energy for alloys (solid solutions) has been developed based on the embedded-atom method. The calculated value of stacking fault energy, 35 mJ/m(2) for 304 austenitic stainless steel, is in a good agreement with the experimental one, 30 mJ/m(2). In the present model we find that the Hirth's empirical relationship is also suitable for alloy.

关键词： Stainless steel

A Novel Condensation Reaction of Alkyl Aryl Ketone with Ethyl Ortho-Formate under Microwave Irradiation

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Chinese Chemical Letters 1998年第1期9卷 1-4页

作者： Yu, JH Hu, YL Yang, SY Yin, YQ Cai, lp Chinese Acad Sci Lanzhou Inst Chem Phys State Key Lab Oxo Synthesis & Select Oxidat Lanzhou 730000 Peoples R China Lanzhou Univ Natl Lab Appl Organ Chem Lanzhou 730000 Peoples R China

Under microwave irradiation, boron trifluoride has been found to mediate a novel condensation reaction of alkyl aryl ketone with ethyl ortho-formate to give a series of new condensation products (5,6,7,8). Their structures were determined by IR, H-1/C-13-NMR, MS spectra, and the crystal structure of 8 was further defined by X-ray diffraction.

关键词： microwave irradiation condensation alkyl aryl ketone

OXIDATIVE　METHYLATION　OF　TOLUENE　WITH　METHANE　OVER　BASIC　ZEOLITE　CATALYSTS　PROMOTED　WITH　ALKALI　METAL　OXIDES

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Chinese Chemical Letters 1996年第3期7卷 229-232页

作者： Zhou, lp.Tao, KY Li, W Su, M Li, HX Hattori, H HOKKAIDO UNIV SAPPOROHOKKAIDO 060JAPAN NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA

The oxidative methylaion of tolucoe with methane to ethylbenzene and Styrene proCeeded over basic Y typezeolite catalyst at 1023K. KY was prepared from NaY raw powder by exchange with 0.5M KOH aqueoussolution at 363K. Loaded KY were preped by impregnating aqueous solutions of LiNO3 and CsNO3 onto *** KY zeolite showed very low C8-yield and selativity. Addition of alkali-metal oxides to the KYzeolite increased greatly the catalytic activity. The Cs2O(6Wt% Cs2O)/KY catalyst gave the highest C3 yield of32.2% with selelectivity of 60.9%.

关键词： BASIC PROM CATA OVER