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Clinical analysis of multiple primary gastrointestinal malignant tumors:A 10-year case review of a single-center

World Journal of Gastrointestinal Oncology 2024年第4期16卷 1204-1212页

作者： Cheng-lou Zhu ling-Zhi Peng The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Surgical Oncology Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND Multiple primary malignant tumors(MPMTs)was first described by Billroth as early as 1889,with the first report published by Warren and Gates in *** then,numerous cases have been reported.A literature review of 1104269 patients with cancer revealed that the incidence of MPMTs ranged from 0.73 to 11.7%.In recent years,however,there has been a significant upward trend in the incidence of this phenomenon,which may be associated with many different factors,including the advancement of modern diagnostic procedures facilitating the examination and diagnosis of more MPMTs,increased exposure to chemotherapy and radiotherapy that exacerbate the risk of new malignant tumors in patients with cancer,and prolonged survival of patients with cancer allowing sufficient time for the development of new primary *** To analyze the incidence,clinical features,treatment factors,prevalence,and prognosis of patients with MPMTs in the gastrointestinal tract treated in a single ***,we analyzed the different tumor combinations,time interval between the occurrence of tumors,and *** This retrospective cohort study analyzed 8059 patients with pathologically confirmed gastrointestinal malignant tumors treated at the Gansu Province Hospital in Lanzhou,Gansu,China between June 2011 and June *** these,85 patients had *** clinical features,treatment factors,prevalence,and prognosis of this latter cohort were *** The incidence of MPMTs in patients with gastrointestinal malignant tumors was 1.05%(85/8059),including 83 double primary malignant tumors and two triple primary malignant tumors of which 57(67.06%)were synchronous MPMTs(SMPMTs)and 28(32.94%)were metachronous MPMTs(MMPMTs).The most frequent associations were found between the rectum colon cancers within the SMPMT category and the gastric-colon cancers within the MMPMT *** the MMPMTs,the median interval was 53 *** overall 1-,3-and 5-year survival rates f

关键词： Multiple primary malignant tumors Clinical characteristics Gastrointestinal tract Prognosis Epidemiology

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An Interactive Collaborative Creation System for Shadow Puppets Based on Smooth Generative Adversarial Networks

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Computers, Materials & Continua 2024年第6期79卷 4107-4126页

作者： Cheng Yang Miaojia lou Xiaoyu Chen Zixuan Ren Department of Industrial Design Hangzhou City UniversityHangzhou310000China College of Computer Science and Technology Zhejiang UniversityHangzhou310000China

Chinese shadow puppetry has been recognized as a world intangible cultural ***,it faces substantial challenges in its preservation and advancement due to the intricate and labor-intensive nature of crafting shadow *** ensure the inheritance and development of this cultural heritage,it is imperative to enable traditional art to flourish in the digital *** paper presents an Interactive Collaborative Creation System for shadow puppets,designed to facilitate the creation of high-quality shadow puppet images with greater *** system comprises four key functions:Image contour extraction,intelligent reference recommendation,generation network,and color adjustment,all aimed at assisting users in various aspects of the creative process,including drawing,inspiration,and content ***,we propose an enhanced algorithm called Smooth Generative Adversarial Networks(SmoothGAN),which exhibits more stable gradient training and a greater capacity for generating high-resolution shadow puppet ***,we have built a new dataset comprising high-quality shadow puppet images to train the shadow puppet generation *** qualitative and quantitative experimental results demonstrate that SmoothGAN significantly improves the quality of image generation,while our system efficiently assists users in creating high-quality shadow puppet images,with a SUS scale score of *** study provides a valuable theoretical and practical reference for the digital creation of shadow puppet art.

关键词： Shadow puppets deep learning image generation co-create

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Population Dynamics in an Advective Environment

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Communications on Applied Mathematics and Computation 2024年第1期6卷 399-430页

作者： King-Yeung Lam Ray Lee Yuan lou Department of Mathematics The Ohio State UniversityColumbusOH43210USA School of Mathematical Sciences CMA-Shanghai and MOE-LSCShanghai Jiao Tong UniversityShanghai200240China

We consider a one-dimensional reaction-diffusion equation describing single-and two-species population dynamics in an advective environment,based on the modeling frameworks proposed by Lutscher et *** *** analyze the effect of rate of loss of individuals at both the upstream and downstream *** the single-species case,we prove the existence of the critical domain size and provide explicit formulas in terms of model *** further derive qualitative properties of the critical domain size and show that,in some cases,the critical domain size is either strictly decreasing over all diffusion rates,or monotonically increasing after first decreasing to a *** also consider competition between species differing only in their diffusion *** two species having large diffusion rates,we give a sufficient condition to determine whether the faster or slower diffuser wins the *** also briefly discuss applications of these results to competition in species whose spatial niche is affected by shifting isotherms caused by climate change.

关键词： Reaction-diffusion-advection Critical domain size Competition Climate change

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Multi-stream signals separation based on space-time-isomeric (SPATIO) array using metasurface antennas

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Science China(Information Sciences) 2024年第2期67卷 181-200页

作者： Yangming lou liang JIN Huiming WANG Zhou ZHONG Junyan DAI PLA Strategic Support Force Information Engineering University School of Information and Communications Engineering Xi'an Jiaotong University 3. State Key Laboratory of Millimeter WavesSoutheast University

In spatial domain signal processing, it is necessary to equip more antennas at the receiver to improve spatial demultiplexing capability. However, increasing the number of antennas under restricted space will reduce antenna spacing and raise the channel correlation, making the number of signal streams spatially demultiplexed much smaller than that of antennas. This paper proposes a method to design a space-timeisomeric(SPATIO) array based on metasurface antennas under wireless multipath conditions. Each antenna in this array has a different pattern and varies independently with time, reducing the channel correlation by superposing multipath at distinct positions and moments. Based on the SPATIO array, we present an array parameter design scheme based on infinity norm minimization, which can maximize the received energy of each stream while separating multi-stream received signals. Simulation results illustrate the performance of the SPATIO array for multi-stream signal reception. Compared with conventional multiple-input multipleoutput arrays, the proposed array can reduce the bit error rate by one order of magnitude under the same simulation conditions.

关键词： multiple-input multiple-output metasurface antenna space-time-isomeric array multipath channel degree of freedom

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Magnetic-biased chiral molecules enabling highly oriented photovoltaic perovskites

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National Science Review 2024年第2期11卷 221-230页

作者： Jing Chen Caner Deger Zhen-Huang Su Kai-li Wang Guang-Peng Zhu Jun-Jie Wu Bing-Chen He Chun-Hao Chen Tao Wang Xing-Yu Gao Ilhan Yavuz Yan-Hui lou Zhao-Kui Wang liang-Sheng liao Institute of Functional Nano&Soft Materials(FUNSOM) Laboratory of Advanced Negative Carbon TechnologiesSoochow University Department of Physics Marmara University Shanghai Synchrotron Radiation Facility(SSRF) Shanghai Advanced Research InstituteChinese Academy of Sciences College of Energy Soochow Institute for Energy and Materials Innovations Soochow University Macao Institute of Materials Science and Engineering Macau University of Science and Technology

The interaction between sites A, B and X with passivation molecules is restricted when the conventional passivation strategy is applied in perovskite（ABX3） photovoltaics. Fortunately, the revolving A-site presents an opportunity to strengthen this interaction by utilizing an external field. Herein, we propose a novel approach to achieving an ordered magnetic dipole moment, which is regulated by a magnetic field via the coupling effect between the chiral passivation molecule and the A-site（formamidine ion） in *** strategy can increase the molecular interaction energy by approximately four times and ensure a well-ordered molecular arrangement. The quality of the deposited perovskite film is significantly optimized with inhibited nonradiative recombination. It manages to reduce the open-circuit voltage loss of photovoltaic devices to 360 mV and increase the power conversion efficiency to 25.22%. This finding provides a new insight into the exploration of A-sites in perovskites and offers a novel route to improving the device performance of perovskite photovoltaics.

关键词： perovskite photovoltaics magnetic moment A-site regulation chiral molecules

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Genome assembly of autotetraploid Actinidia arguta highlights adaptive evolution and enables dissection of important economic traits

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Plant Communications 2024年第6期5卷 173-192页

作者： Xue-Mei Lu Xiao-Fen Yu Guo-Qiang li Ming-Hao Qu Huan Wang Chuang liu Yu-Ping Man Xiao-Han Jiang Mu-Zi li Jian Wang Qi-Qi Chen Rui Lei Cheng-Cheng Zhao Yun-Qiu Zhou Zheng-Wang Jiang Zuo-Zhou li Shang Zheng Chang Dong Bai-lin Wang Yan-Xiang Sun Hui-Qin Zhang Jie-Wei li Quan-Hui Mo Ying Zhang Xin lou Hai-Xu Peng Ya-Ting Yi He-Xin Wang Xiu-Jun Zhang Yi-Bo Wang Dan Wang li li Qiong Zhang Wen-Xia Wang Yongbo liu Lei Gao Jin-Hu Wu Yan-Chang Wang CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Wuhan Botanical GardenChinese Academy of SciencesWuhanHubeiChina Key Laboratory of Western China’s Environmental Systems(Ministry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhouGansuChina College of life Sciences University of Chinese Academy of SciencesBeijingChina Wuhan Frasergen Bioinformatics Co. LtdWuhanHubeiChina Institute of Soil and Fertilizer Anhui Academy of Agricultural SciencesHefeiChina College of Agricultural Sciences Xichang UniversityXichangSichuanChina Department of Horticulture Heilongjiang Academy of Agricultural SciencesHarbinHeilongjiangChina College of life Sciences Langfang Normal UniversityLangfangHebeiChina Institute of Horticulture Zhejiang Academy of Agricultural SciencesHangzhouZhejiangChina Guangxi Institute of Botany Chinese Academy of SciencesGuilinGuangxiChina Xi’an Botanical Garden of Shaanxi Province Institute of Botany of Shaanxi ProvinceXi’anShaanxiChina Institute of Modern Agricultural Research Dalian UniversityDalianLiaoningChina Bioinformatics Center College of Plant Science and TechnologyBeijing University of AgricultureBeijingChina College of Agriculture Eastern Liaoning UniversityDandongLiaoningChina Dalian Institute of Chemical Physics Chinese Academy of SciencesDalianLiaoningChina State Environmental Protection Key Laboratory of Regional Eco-process and Function Assessment Chinese Research Academy of Environmental SciencesBeijingChina Hubei Hongshan Laboratory WuhanHubeiChina The New Zealand Institute for Plant and Food Research limited AucklandNew Zealand

Actinidia arguta,the most widely distributed Actinidia species and the second cultivated species in the genus,can be distinguished from the currently cultivated Actinidia chinensis on the basis of its small and smooth fruit,rapid softening,and excellent cold *** evolution of tetraploid Actinidia species and the genetic basis of their important agronomic traits are still ***,we generated a chromosome-scale genome assembly of an autotetraploid male *** *** genome assembly was 2.77 Gb in length with a contig N50 of 9.97 Mb and was anchored onto 116 *** and clustering of 101 geographically representative accessions showed that they could be divided into two geographic groups,Southern and Northern,which first diverged 12.9 million years *** underwent two prominent expansions and one demographic bottleneck from the midPleistocene climate transition to the late *** genomics studies using paleoclimate data enabled us to discern the evolution of the species’adaptation to different historical *** genes(AaCEL1,AaPME1,and AaDOF1)related to flesh softening were identified by multi-omics analysis,and their ability to accelerate flesh softening was verified through transient expression assays.A set of genes that characteristically regulate sexual dimorphism located on the sex chromosome(Chr3)or autosomal chromosomes showed biased expression during stamen or carpel *** chromosome-level assembly of the autotetraploid *** genome and the genes related to important agronomic traits will facilitate future functional genomics research and improvement of ***.

关键词： kiwiberry dioecism adaptive evolution paleoclimate GEA rapid softening

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一种面向多任务的无人机辅助的通信网络资源分配与轨迹优化研究

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电子与信息学报 2024年第7期46卷 2748-2756页

作者：裴二荣娄宇涵李永刚黎伟重庆邮电大学通信与信息工程学院重庆400065 重庆金美通信有限公司重庆400035

装载各种有效荷载的无人机(UAV)能够实现传感、通信和计算等多任务,因而常被部署到数据采集(DA)和辅助计算等领域。但是到目前为止,绝大多数研究仅专注于单一功能的无人机辅助的通信网络资源分配与轨迹优化,对于面向多任务的资源分配和... 详细信息

装载各种有效荷载的无人机(UAV)能够实现传感、通信和计算等多任务,因而常被部署到数据采集(DA)和辅助计算等领域。但是到目前为止,绝大多数研究仅专注于单一功能的无人机辅助的通信网络资源分配与轨迹优化,对于面向多任务的资源分配和轨迹优化问题还未解决。为此,该文提出一种综合考虑无人机数据采集、数据广播以及计算任务卸载的无人机辅助的通信网络资源优化的分配策略,旨在通过联合优化传输占空比、用户发射功率与无人机轨迹,在满足目标位置采集数据实时广播的前提下,最大化用户卸载量。为了解决多变量耦合优化问题,提出了基于块坐标下降(BCD)和连续凸逼近(SCA)的高效迭代优化算法,将耦合优化问题分解为3个子问题进行迭代优化。最后,大量仿真结果表明,该算法在公平性和总卸载计算量方面都优于其他测试方案。

关键词：无人机通信移动边缘计算数据采集凸优化

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Activation of glutamatergic neurons in the somatosensory cortex promotes remyelination in ischemic vascular dementia

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Fundamental Research 2024年第1期4卷 188-198页

作者： Yi-Ting Zhou Da-Dao An Yi-Xin Xu Ying Zhou Qing-Qing li Hai-Bin Dai Xiang-Nan Zhang Yi Wang Min lou Zhong Chen Wei-Wei Hu Department of Pharmacology and Department of Pharmacy of the Second Affiliated Hospital NHC and CAMS Key Laboratory of Medical NeurobiologySchool of Basic Medical SciencesCollege of Pharmaceutical SciencesZhejiang University School of MedicineHangzhou 310058China Department of Pharmacy Sir Run Run Shaw HospitalHangzhou 310012China Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical SciencesZhejiang Chinese Medical UniversityHangzhou 310053China Department of Neurology the Second Affiliated Hospital of Zhejiang UniversitySchool of MedicineHangzhou 310003China

Chronic cerebral hypoperfusion can cause progressive demyelination as well as ischemic vascular dementia,however no effective treatments are ***,based on magnetic resonance imaging studies of patients with white matter damage,we found that this damage is associated with disorganized cortical *** a mouse model,optogenetic activation of glutamatergic neurons in the somatosensory cortex significantly promoted oligodendrocyte progenitor cell(OPC)proliferation,remyelination in the corpus callosum,and recovery of cognitive ability after cerebral *** therapeutic effect of such stimulation was restricted to the upper layers of the cortex,but also spanned a wide time window after ***,enhancement of glutamatergic neuron-OPC functional synaptic connections is required to achieve the protection effect of activating cortical glutamatergic ***,skin stroking,an easier method to translate into clinical practice,activated the somatosensory cortex,thereby promoting OPC proliferation,remyelination and cognitive recovery following cerebral *** summary,we demonstrated that activating glutamatergic neurons in the somatosensory cortex promotes the proliferation of OPCs and remyelination to recover cognitive function after chronic cerebral *** should be noted that this activation may provide new approaches for treating ischemic vascular dementia via the precise regulation of glutamatergic neuron-OPC circuits.

关键词： Chronic cerebral hypoperfusion Optogenetic stimulation Oligodendrocyte progenitor cellischemic vascular dementia Glutamatergic neuron Remyelination

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Strategies for Video Producers to Tell Their Good Stories Under the 5W Model of Communication

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教育技术与创新 2024年第1期6卷 50-66页

作者： Wenqian Hong Yixuan Jiang Rui Wen Wenyu Chen Nan lou Jinxuan Deng Jiayun li Hanfei li Dan Ye School of Foreign Studies Wenzhou UniversityChina

In recent years,with the rise of video media such as YouTube and Tik Tok,the short video creation industry has *** to spread China's excellent culture and how to“tell a good Chinese story”have become a hot *** the 5W Model of Communication as a framework for analysis,this paper selects Chinese short videos with high popularity on YouTube as the object of the *** found that the success of these videos was associated with five factors in the process of communication,which are communication main forces,communication content,communication channels,communication audience,and audience *** theoretical and data analysis,the study concluded five strategies in video production to help promote Intercultural communication.

关键词： International communication communication strategy video production

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Lagrangian coherent structure analysis on transport of Acetes chinensis along coast of lianyungang,China

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Journal of Oceanology and limnology 2024年第1期42卷 345-359页

作者： Kexin WANG Xueqing ZHANG Qi lou Xusheng XIANG Ying XIONG College of Environmental Science and Engineering Ocean University of ChinaQingdao 266100China Key Laboratory of Marine Environment and Ecology Ministry of Education of ChinaOcean University of ChinaQingdao 266100China Jiangsu Marine Fisheries Research Institute Nantong 226007China

Spatial heterogeneity or“patchiness”of plankton distributions in the ocean has always been an attractive and challenging scientific issue to *** focused on the accumulation and dynamic mechanism of the Acetes chinensis in the lianyungang nearshore licensed fishing *** Lagrangian frame approaches including the Lagrangian coherent structures theory,Lagrangian residual current,and Lagrangian particle-tracking model were applied to find the transport pathways and aggregation characteristics of Acetes *** exist some material transport pathways for Acetes chinensis passing through the licensed fishing area,and Acetes chinensis is easy to accumulate in the licensed fishing *** main mechanism forming this distribution pattern is the local circulation induced by the nonlinear interaction of topography and tidal *** the Lagrangian coherent structure analysis and the particle trajectory tracking indicate that Acetes chinensis in the licensed fishing area come from the nearshore *** work contributed to the adjustment of licensed fishing area and the efficient utilization of fishery resources.

关键词： plankton accumulation hydrodynamic model Lagrangian particle-tracking model Lagrangian analysis

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