检索结果-南通市图书馆

2型糖尿病患者正常水平血清肌酐与糖尿病肾病的前瞻性队列研究

在线全文

学校读者我要写书评

暂无评论

中华内分泌代谢杂志 2024年第5期40卷 380-385页

作者：程旦汤芳丽汪文俊刘欢欢李洮俊楼青青海南医学院国际护理学院海口571199 海南医学院第一附属医院 (海南省)代谢性疾病临床医学研究中心海口570102 海南省人民医院内分泌科海口570311 中国台湾李氏联合诊所内分泌科中国台湾屏东900

目的探讨正常水平血清肌酐(serum creatinine, Scr)与2型糖尿病(type 2 diabetes mellitus, T2DM)患者糖尿病肾病(diabetic kidney disease, DKD)的关系。方法本研究为前瞻性队列研究, 选取2002年1月1日至2018年12月31日在中国台湾李氏... 详细信息

目的探讨正常水平血清肌酐(serum creatinine, Scr)与2型糖尿病(type 2 diabetes mellitus, T2DM)患者糖尿病肾病(diabetic kidney disease, DKD)的关系。方法本研究为前瞻性队列研究, 选取2002年1月1日至2018年12月31日在中国台湾李氏联合诊所6个中心定期随访的T2DM患者作为研究对象。基线时患者无DKD, 收集患者的一般资料、实验室检查指标。根据患者随访时间内是否发生DKD将患者分为DKD组和无DKD组(nondiabetic kidney disease, NDKD)。暴露因素是Scr(μmol/L)值, 并作为分类变量, 根据Scr四分位数分为4组:Q1组(Scr74.27 μmol/L时, 更应高度关注DKD发生的可能性。

关键词：糖尿病肾病糖尿病 2型血清肌酐

2型糖尿病患者体重变异性与糖尿病肾病发病风险的相关性

在线全文

学校读者我要写书评

暂无评论

中华医学杂志 2024年第10期104卷 742-750页

作者：方雍乔汪文俊刘欢欢汤芳丽李洮俊楼青青海南医学院国际护理学院，海口571199 海南医学院第一附属医院代谢性疾病临床医学研究中心，海口570102 海南省人民医院内分泌科，海口570311 中国台湾李氏联合诊所内分泌科，屏东900

目的探讨2型糖尿病(T2DM)患者不同体重变异性指标与糖尿病肾病(DKD)发病风险的关系。方法回顾性队列研究。回顾性分析2002—2018年在中国台湾李氏联合诊所进行个案管理的2180例无DKD的T2DM患者的临床资料,女1103例,男1077例,年龄(64.8±... 详细信息

目的探讨2型糖尿病(T2DM)患者不同体重变异性指标与糖尿病肾病(DKD)发病风险的关系。方法回顾性队列研究。回顾性分析2002—2018年在中国台湾李氏联合诊所进行个案管理的2180例无DKD的T2DM患者的临床资料,女1103例,男1077例,年龄(64.8±12.4)岁。对患者进行定期随访,至少2年,每年监测其代谢指标,依据患者每年记录的体质指数(BMI)计算其独立于均值的变异性(BMI-VIM)、平均真实变异性(BMI-ASV)、变异系数(BMI-CV)和标准差(BMI-SD)。根据4种体重变异性指标的四分位数,分别将患者分为Q_(1)、Q_(2)、Q_(3)、Q_(4)四组。根据随访结束时是否发生DKD将患者分为DKD组和无DKD组(NDKD组)。采用Cox比例风险回归模型分析4种体重变异性指标与DKD发病风险的关系,再以BMI<28 kg/m^(2)为非肥胖组,BMI≥28 kg/m^(2)为肥胖组进行亚组分析,探讨4项体重变异性指标对DKD发病风险的影响。结果所有患者经过(4.55±2.13)年随访后,904例患者发生DKD。与NDKD组相比,DKD组患者女性较多、年龄较大、糖尿病病程更长、使用胰岛素的比例更高、腰臀比更大,BMI-VIM、BMI-ASV、BMI-CV、BMI-SD、收缩压、舒张压、尿白蛋白/肌酐比值均较高,服用降糖药的比例、估算的肾小球滤过率、高密度脂蛋白胆固醇水平均较低,两组差异均有统计学意义(均P<0.05)。Cox比例风险回归结果显示,在校正系列影响因素后,T2DM患者发生DKD的风险随着BMI-SD、BMI-CV、BMI-VIM和BMI-ASV的增加而增加。在BMI-VIM分组中,与Q_(1)组相比,Q_(4)组发生DKD的风险增加22.4%[HR=1.224(95%CI:1.008~1.487),P=0.041];在BMI-ASV分组中,与Q_(1)组相比,Q_(4)组发生DKD的风险增加51.1%[HR=1.511(95%CI:1.240~1.841),P<0.01];在BMI-CV分组中,与Q_(1)组相比,Q_(4)组发生DKD的风险增加22.2%[HR=1.222(95%CI:1.006~1.485),P=0.044];在BMI-SD分组中,与Q_(1)组相比,Q_(4)组发生DKD的风险增加22.2%[HR=1.222(95%CI:1.002~1.490),P=0.048]。亚组分析显示,非肥胖组中以BMI-ASV分组时,在校正系列影响因素后,与Q_(1)组相比,Q_(4)组发生DKD风险最高[HR=1.551(95%CI:1.228~1.958),P<0.001];肥胖组中以BMI-ASV分组时,在校正系列影响因素后,与Q_(1)组相比,Q_(4)组发生DKD风险最高[HR=1.703(95%CI:1.168~2.485),P=0.006]。结论BMI-VIM、BMI-ASV、BMI-CV、BMI-SD的升高会使T2DM患者发生DKD的风险增加。

关键词：糖尿病,2型糖尿病肾病体重变异性相关性

甘油三酯-葡萄糖指数及其变异性对2型糖尿病肾脏病的影响

在线全文

学校读者我要写书评

暂无评论

中华糖尿病杂志 2024年第5期16卷 519-526页

作者：邢丽丽汤芳丽汪文俊刘欢欢李洮俊楼青青海南医学院国际护理学院海口571199 海南医学院第一附属医院代谢性疾病临床医学研究中心海口570102 海南省人民医院内分泌科海口570311 台湾李氏联合诊所内分泌科中国台湾屏东900

目的探讨2型糖尿病(T2DM)患者甘油三酯-葡萄糖(TyG)指数及其变异性对糖尿病肾脏病(DKD)的影响。方法为前瞻性队列研究。选取2002年1月1日至2018年12月31日在台湾地区李氏联合诊所6个中心定期就诊且基线时无DKD的1986例T2DM患者作为研究... 详细信息

目的探讨2型糖尿病(T2DM)患者甘油三酯-葡萄糖(TyG)指数及其变异性对糖尿病肾脏病(DKD)的影响。方法为前瞻性队列研究。选取2002年1月1日至2018年12月31日在台湾地区李氏联合诊所6个中心定期就诊且基线时无DKD的1986例T2DM患者作为研究对象,并对其进行前瞻性随访。收集患者的年龄、性别、血肌酐、甘油三酯(TG)、空腹血糖(FPG)、尿微量白蛋白和尿肌酐,并计算TyG指数、估算的肾小球滤过率(eGFR)和尿白蛋白/肌酐比值(UACR),依据基线和随访年每年1次的TyG指数,计算TyG指数的均值和TyG指数变异性。根据《中国糖尿病肾脏病防治指南(2021年版)》的诊断标准诊断DKD。根据随访结束时患者是否发生DKD将其分为DKD组和无糖尿病肾脏病(NDKD)组,按照TyG指数的均值将患者分为T_(1)组(TyG指数均值<8.67)、T_(2)组(8.67≤TyG指数均值<9.09)和T_(3)组(TyG指数均值≥9.09),根据TyG指数的变异性将患者分为T′_(1)组(TyG指数变异性<0.29)、T′_(2)组(0.29≤TyG指数变异性<0.43)和T′_(3)组(TyG指数变异性≥0.43)。采用两独立样本t检验比较DKD组和NDKD组患者相关指标的差异,采用Cox比例风险回归模型研究TyG指数及其变异性与DKD之间的关系,采用广义线性混合模型探讨TyG指数等因素对DKD的影响。结果随访时间为(7.27±3.48)年。随访结束时,1986例T2DM患者中,DKD组676例,NDKD组1310例。与NDKD组相比,DKD组T2DM患者的UACR、TyG指数均值及TyG指数变异性均更高,而eGFR更低(均P<0.05)。Cox比例风险回归模型结果显示,校正混杂变量后,相较于T_(1)组,T_(3)组T2DM患者发生DKD的风险最高,较T 1组升高68.9%(HR=1.689,95%CI 1.376~2.073,P<0.001);相较于T′1组,T′3组T2DM患者发生DKD的风险最高,较T′_(1)组升高74.2%(HR=1.742,95%CI 1.421~2.135,P<0.001)。广义线性混合模型结果显示,随访过程中每年的TyG指数对DKD的发生有明显影响(β=0.244,95%CI 0.111~0.376,P<0.001)。结论TyG指数及其变异性的升高都会增加T2DM患者的DKD发病风险,TyG指数及其变异性均是DKD发生的独立危险因素。

关键词：糖尿病肾病糖尿病,2型甘油三酯-葡萄糖指数变异性

Effect of structured education program on physiological and psychosocial outcomes in type 2 diabetes patients:A randomized controlled trial

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Nursing 2021年第2期3卷 72-78页

作者： Qianqian ZHOU Xiaorong LIU Jianing LI Jinlan YAO qingqing lou Department of Medical College Nursing College of Huzhou UniversityHuzhouChina Department of Nursing Affiliated Hospital of Integrated Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingChina Physical Examination Center Affiliated Hospital of Integrated Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingChina Deparement of General Affairs Office Hainan General HospitalHaikouChina

Objective:This study was conducted to compare the effect of structured education program versus traditional diabetes education on insulin injection technique as well as physiologically and psychosocially related outcomes in adults with Type 2 *** and Methods:This study was a randomized controlled ***,71 Type 2 diabetes patients of using the insulin pen were enrolled and randomly divided into the intervention group(n=36)and the control group(n=35)according to random number table *** in the intervention group received structured education program,while patients in the control group received traditional diabetes *** levels of glycosylated hemoglobin(HbA1c),blood glucose,and lipids were monitored before and 3 months after intervention,and the insulin injection techniques,diabetes distress,and diabetes self-management skills between groups were assessed after 3 ***:Finally,65 participants(intervention group:n=33,control group:n=32)finished the *** the intervention,HbA1c was lower(7.42±0.80 vs.8.35±1.40,P=0.002),fasting blood glucose(FBG)was lower(7.27±1.06 vs.9.40±3.16,P<0.001),and postprandial blood glucose(PBG)was lower(10.33±2.20 vs.12.77±4.94,P=0.012)in the intervention group than in the control *** statistically significance was identified between the two groups in scores of Diabetes Distress Scale and summary of diabetes self-care ***:Patients with Type 2 diabetes received structured education program,with greater improvements achieved in HbA1c,FBG,PBG,and measures about insulin injection techniques compared to the traditional education group,but there was no significant difference in diabetes distress or self-management behavior between groups.

关键词： Diabetes injection techniques insulin structured education

Self-monitoring of blood glucose in type 2 diabetic patients in China：current status and influential factors

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第2期127卷 201-207页

作者： Yuan Li Guo Xiaohui Xiong Zhenzhen lou qingqing Shen Li Zhao Fang Sun Zilin Li Jianwei Department of Endocrinology West China Hospital of Sichuan University Chengdu Sichuan 610041 China Department of Endocrinology First Hospital of Peking University Beijing 100034 China Department of Health Education Jiangsu Province Hospital of Integrated Traditional Chinese and Western Medicine Nanjing Jiangsu 210028 China Nursing Department Beijing Tsinghua Chang Gung Hospital of Tsinghua University Beijing 100027 China Department of Endocrinology China-Japan Friendship Hospital Beijing 100029 China Department of Internal Medicine Southeast University Zhongda Hospital Nanjing Jiangsu 210009 China

Background Self-monitoring of blood glucose （SMBG） by individuals with type 2 diabetes （T2D） is crucial for long-term health,yet numerous cultural,economic and health factors can reduce *** studies on SMBG adherence have come out of the US and Europe,and their relevance to Asia is *** aims of the present study were to assess the current state of SMBG in China and analyze demographic and diabetes-related characteristics that may influence *** In this multi-center,cross-sectional study,5 953 individuals with T2D from 50 medical centers in 29 provinces across China filled out a standardized questionnaire that requested information on demographic characteristics,education level,occupation,income,lifestyle risk factors,duration of diabetes,chronic complications,and frequency of *** were also asked whether their glycosylated hemoglobin （HbA1c） had been checked in the past 6 *** most recent values for fasting plasma glucose,2-hour postprandial blood glucose and HbA1c were recovered from medical *** Only 1 130 respondents （18.98％） performed SMBG with the recommended frequency,while 4 823 （81.02％） did *** fact,nearly 2 105 （35.36％） reported never performing *** the subset of 3 661 individuals on insulin therapy,only 266 （7.27％） performed SMBG at least once a day,while 1 210 （33.05％） never performed *** contrast,895 of 2 292 individuals （39.05％） on diet/exercise therapy or oral hypoglycemic therapy never performed *** Logistic regression identified several factors associated with SMBG adherence：female gender,higher education level,higher income,longer T2D duration and education about *** SMBG adherence in our Chinese population with T2D was less frequent than that in developed *** factors influence SMBG adherence：gender,education level,income,T2D duration,therapy regimen and exposure to education about SMBG.

关键词： diabetes mellitus, type 2 blood glucose self-monitoring health education

Rejection of insulin therapy among patients with type 2 diabetes in China： reasons and recommendations

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第20期127卷 3530-3536页

作者： Xiong Zhenzhen Yuan Li Guo Xiaohui lou qingqing Zhao Fang Shen Li Zhang Mingxia Sun Zilin Department of Endocrinology West China Hospital of SichuanUniversity Chengdu Sichuan 610041 China Department of Endocrinology First Hospital of Peking UniversityBeijing 100034 China Department of Health Education Jiangsu Province IntegratedChinese and Western Medicine Hospital Nanjing Jiangsu 210028China Department of Endocrinology China-Japan Friendship HospitalBeij hag 100029 China Beijing Tsinghua Hospital Beijing 102218 China

Background Insulin injection therapy is one of the most effective treatments for type 2 diabetes meUitus （T2DM）. Many people with T2DM in western countries resist starting insulin therapy; whether the same is true in China is unknown. This survey-based study assessed acceptance and rejection of insulin therapy among individuals with T2DM in China and self- reported reasons for these therapy choices. It also examined what methods may be useful for increasing the rate of insulin acceptance. Methods A multi-center, cross-sectional survey was conducted between April and July 2010 to a convenience sample of inpatients and outpatients at 50 medical centers across 29 administrative divisions in China. Data were collected on sociodemographic and T2DM characteristics, therapy regime, and attitudes toward insulin therapy. Results A total of 6 043 patients were surveyed, and 5 961 complete questionnaires （98.6%） were used in the analysis. Just over half the respondents （3 460, 58.0%） reported negative attitudes to insulin therapy, including 2 508 of the 4 469 patients （56.1%） whose physicians had recommended it to them. Of the patients counseled to use insulin, 800 （17.9%） were unwilling to start therapy and cited the following reasons： inconvenience （64.3%）; concerns over addiction （24.6%）; pain （14.3%）; side effects （14.1%）; and high cost （13.6%）. Logistic regression suggested that respondents would be more willing to undertake insulin therapy if they had received diabetes education, had positive attitudes to the treatment, had higher glycosylated hemoglobin level, or had suffered diabetes for a longer period or with more complications. Conclusions Patients with T2DM in China are often resistant to insulin therapy if they have been diagnosed with the disease for a relatively short time or if the disease has been relatively mild. Educating patients on the benefits of insulin therapy, not only at the initial diagnosis with T2DM but also when insulin therapy becomes necessary,

关键词： diabetes mellitus, type 2 insulin drug therapy rejection

Study on the correlation between bandage bandage and pressure therapy of lymphedema

在线全文

学校读者我要写书评

暂无评论

中西医结合护理（中英文） 2020年第10期6卷 513-518页

作者： WANG Bei Li Haihong lou qingqing LI Jianing WANG Xiaoyuan XU Chenyun Department of Nursing Affiliated Hospital of Integrated Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingJiangsu210028 Department of Health Education Affiliated Hospital of Integrated Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingJiangsu210028 Department of Gynecology Clinic Affiliated Hospital of Integrated Traditional Chinese and Western Medicine Nanjing University of Chinese Medicine Nanjing Jiangsu 210028 Department of Nursing The First People's Hospital of Lianyungang Lianyungang Jiangsu 222002 Longhua District of Hainan people's Hospital Haikou Hainan 570102

To explore the effects of bandage technology and pressure therapy in breast cancer with *** A total of 91 patients,with breast cancer-related lymphedema and hospitalized in a third-class hospital in Jiangsu Province from May to December,2018,were selected and sequenced in class“ABC”in the order of *** patients in class“A”were enrolled in“8”shaped bandaging *** patients in class“B”were enrolled in“5”spiral bandaging *** patients in class“C”were enrolled in combined bandage *** primary outcome was the degree of limb swelling used by multiple-frequency bioelectrical impedance *** outcomes were the amount of bandage losses,counting 24-hour bandage loose occurrences and patients *** outcomes were evaluated both before and after *** After treatment,there was a significant difference in the regression of limb swelling in all three groups(P<0.05).However,the largest amplitude of regression was observed in combined bandage group(limb circumference ratio:53%and tissue water ratio:68%).Although“8”bandaging group had large material,bandage cost and minimum comfort,the bandage has good stability and no case of 24-hour bandage loose occurrences was found in this ***“5”partial binding group had an advantage in the amount of bandage losses and comfort level,but among which 3 patients had the phenomenon of loose bandage at the *** combined bandage group had the best therapeutic effect in limb swelling and patients satisfaction(P<0.05).Conclusion The combined bandage group significantly decreased the degree of limb swelling and 24-hour bandage loose ***,this treatment improved the degree of patients’*** treatment of“8”shaped bandaging combined with spiral bandaging is worthy of clinical promotion.

关键词： bandage pressure bandage lymphedema complex decongestion therapy correlation study

Ren-integrable and ren-symmetric integrable systems

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2024年第3期76卷 62-69页

作者： S Y lou School of Physical Science and Technology Ningbo UniversityNingbo315211China

A new type of symmetry,ren-symmetry,describing anyon physics and corresponding topological physics,is ***-symmetry is a generalization of super-symmetry which is widely applied in super-symmetric physics such as super-symmetric quantum mechanics,super-symmetric gravity,super-symmetric string theory,super-symmetric integrable systems and so *** and Grassmann numbers are,in some sense,dual conceptions,and it turns out that these conceptions coincide for the ren situation,that is,a similar conception of ren-number(R-number)is devised for *** particular,some basic results of the R-number and ren-symmetry are exposed which allow one to derive,in principle,some new types of integrable systems including ren-integrable models and ren-symmetric integrable *** examples of ren-integrable KdV-type systems and ren-symmetric KdV equations are explicitly given.

关键词： symmetries integrable systems anyon physics extended supersymmetry ren-symmetry

抗阻运动在非酒精性脂肪性肝病治疗中的研究进展

在线全文

学校读者我要写书评

暂无评论

武汉体育学院学报 2015年第4期49卷 91-95页

作者：杨圣楠楼青青南京中医药大学护理学院江苏南京210023 南京中医药大学附属江苏省中西医结合医院健康教育科江苏南京210028

抗阻运动在许多疾病管理中发挥着越来越重要的作用。近年来,国外学者将抗阻运动运用于非酒精性脂肪性肝病的治疗过程,并取得了有益效果。介绍非酒精性脂肪性肝病的发病机制和代谢特点,回顾国外抗阻运动的作用效果和运动处方,旨在为NAFL... 详细信息

抗阻运动在许多疾病管理中发挥着越来越重要的作用。近年来,国外学者将抗阻运动运用于非酒精性脂肪性肝病的治疗过程,并取得了有益效果。介绍非酒精性脂肪性肝病的发病机制和代谢特点,回顾国外抗阻运动的作用效果和运动处方,旨在为NAFLD防治的运动研究提供参考资料。

关键词：抗阻运动非酒精性脂肪性肝病运动处方