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歧口凹陷滨海断裂带热流体活动及其对油气成藏的影响

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石油学报 2014年第4期35卷 673-684页

作者：龙华山向才富牛嘉玉魏立春中国石油勘探开发研究院北京100083 中国石油大学油气资源与探测国家重点实验室北京102249 中国石油大学盆地与油藏研究中心北京102249

热流体能够影响沉积盆地内物质组分的重新分配,如矿物的溶解和油气相态的变化,以及输导系统的热异常,通常沿断裂分布。滨海断裂带为控制烃源岩展布的断裂之一,同时也是流体热异常活动的场所。利用有机地球化学、流体包裹体、气体地球化... 详细信息

热流体能够影响沉积盆地内物质组分的重新分配,如矿物的溶解和油气相态的变化,以及输导系统的热异常,通常沿断裂分布。滨海断裂带为控制烃源岩展布的断裂之一,同时也是流体热异常活动的场所。利用有机地球化学、流体包裹体、气体地球化学、成岩矿物及地层水化学特征等对研究区内流体的热活动进行了研究,为油气沿断裂发生运移和聚集提供了证据,进一步指明了油气勘探的有利方向。热流体沿断裂上涌发生热对流对局部温度场的改变体现在以下几个方面:①镜质体反射率异常反映局部烃源岩受局部温度场的变化发生热演化异常;②成岩期形成的流体包裹体均一温度大于其最大埋深时的温度;③黏土矿物出现同一深度段多类型和同一类型多层段的演化异常;④储层碎屑矿物颗粒的热蚀变。热流体对物质场的改变主要体现在以下几个方面:①热流体带来了深部幔源的无机CO_2于浅层富集成藏;②大量高于卤水矿化度的深部流体渗入发生流体-岩石相互作用,导致储层中存在高矿化度的地层水;③储层早成岩期胶结于孔隙的碳酸盐类等矿物溶蚀形成多个次生孔隙带,进一步证实了水-岩相互作用,次生孔隙的发育来源于碳酸盐类矿物的溶解和重新分布,在一定程度上控制储层的物性;④热流体携带的大量物质发生流体-岩石相互作用导致靠近断裂带的岩石中所含微量元素异常。上述证据均指示了烃类流体能够沿断裂和渗透性砂岩储层发生运移,并可能聚集成藏形成大油气田。

关键词：热流体活动热效应油气运移与聚集歧口凹陷渤海湾盆地

NUMERICAL SIMULATION AND ANALYSIS ON THE HEMODYNAMICS OF AN ELASTIC ANEURYSM

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Journal of Hydrodynamics 2008年第2期20卷 216-224页

作者： ZHAO Jun-wei YIN Wen-yi DING Guang-hong YANG Xin-jian SHI Wan-chao ZHANG Xiao-long Department of Mechanics and Engineering Science Fudan University Shanghai 200433 China Beijing Institute ofNeurosurgery Beijing 100050 China huashan Hospital Affiliated to Fudan University Shanghai 200040 China

Intracranial aneurysms are pathological dilatations which endanger people＇s health. Hemodynamics is thought to be an important factor in the pathogenesis and treatment of aneurysms. To date, the bulk of investigations into hemodynamics have been conducted by making use of mathematically idealized models for rigid aneurysms and associated arteries. However the walls of aneurysms and associated arteries are elastic in vivo. This study shows the differences of the simulation between elastic and rigid wall models. The numerical simulation of elastic aneurysm model is made fi＇om a representative Digital Subtraction Angiography （DSA） image and calculated with CFD software to get the wall deformation and the velocity field. Then the results are analyzed. By comparing the simulation results of the two models from their velocity vectors and shear stress distribution, many differences can be noted. The main difference exists in the distribution of velocity magnitude at some sections, with one outlet having obviously off-center distribution for the elastic wall model. The currents of the distribution of wall shear stress along the wall of aneurysm simulated in rigid and elastic wall models were similar. But there were apparent differences between the two models on the values of wall shear stress especially at the neck of aneurysm. The off-center distribution of velocity magnitude affects the distribution of wall shear stress and the exchange of substance through the wall. The analysis demonstrated clearly that the results of 2-D elastic numerical simulation were in good agreement with the clinical and pathological practice. The results of this study play an important role in the formation, growth, rupture and prognosis of an aneurysm on clinic application.

关键词： aneurysm 2-D numerical simulation elastic wall medical image

Comprehensive optimization of piezoelectric coefficient and depolarization temperature in Mn-doped Bi_(0.5)Na_(0.5)TiO_(3)-Bi_(0.5)K_(0.5)TiO_(3)-BaTiO_(3)lead-free piezoceramics

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Journal of Materials Science & Technology 2024年第5期172卷 255-263页

作者： huashan Zheng Enwei Sun Huajie Luo Xiaoyu Zhang Yixiao Yang Bin Yang Rui Zhang Shantao Zhang Wenwu Cao Condensed Matter Science and Technology Institute School of Instrumentation Science and EngineeringHarbin Institute of TechnologyHarbin150080China Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing100083China National Laboratory of Solid State Microstructures Department of Materials Science and EngineeringCollege of Engineering and Applied Science&Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing210093China Department of Mathematics and Materials Research Institute The Pennsylvania State UniversityUniversity ParkPennsylvania16802United States of America

Lead-free Bi_(_(0.5))Na_(_(0.5))TiO_(3)(BNT)piezoelectric ceramics have the advantages of large coercive fields and high Curie *** the improvement of piezoelectric coefficient(d 33)is usually accompanied by a huge sacrifice of depolarization temperature(T d).In this work,a well-balanced performance of d 33 and T d is achieved in MnO_(2)-doped 0.79(Bi_(_(0.5))Na_(_(0.5))TiO_(3))-0.14(Bi_(0.5)K_(0.5)TiO_(3))-0.07BaTiO_(3)ternary *** in-corporation of 0.25 mol%MnO_(2)enhances the d 33 by more than 40%,while T d remains almost unchanged(i.e.,d 33=181 pC/N,T d=184℃).X-ray diffraction(XRD)shows that an appropriate fraction of the small axis-ratio ferroelectric phase(pseudo-cubic,P c)coexists with the long-range ferroelectric phase(tetrag-onal,T)under this MnO_(2)*** force microscopy(PFM)has revealed a special domain configuration,namely large striped and layered macro domains embedded with small *** study provides a distinctive avenue to design BNT-based piezoelectric ceramics with high piezoelectric performance and temperature stability.

关键词： BNT-BKT-BT ceramics Mn doping Piezoelectric Depolarization temperature Phase structure

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克拉美丽气田有效烃源灶分布及其控藏作用

新疆石油地质 2014年第5期35卷 500-506页

作者：龙华山李剑王绪龙魏立春谢增业廖健德向才富中国石油勘探开发研究院北京100083 中国石油大学教育部石油与天然气成藏机理重点实验室北京102249 中国石油勘探开发研究院廊坊分院河北廊坊065000 中国石油新疆油田分公司新疆克拉玛依834000

有效烃源灶的展布决定了油气勘探的领域。石炭系烃源岩与火山岩密切共生,地震资料品质受火山岩高速带屏蔽等因素的影响,准噶尔盆地克拉美丽气田的烃源灶空间分布范围争议较大。根据地球物理资料和大量的烃源岩分析测试资料,对克拉美丽... 详细信息

有效烃源灶的展布决定了油气勘探的领域。石炭系烃源岩与火山岩密切共生,地震资料品质受火山岩高速带屏蔽等因素的影响,准噶尔盆地克拉美丽气田的烃源灶空间分布范围争议较大。根据地球物理资料和大量的烃源岩分析测试资料,对克拉美丽气田的有效烃源灶的空间分布特征进行了详细的研究。研究表明,滴水泉凹陷、东道海子凹陷和五彩湾凹陷是卡拉麦里山前石炭系烃源岩的3个厚度中心,其厚度均大于450 m.烃源岩有机质类型以Ⅱ型和Ⅲ型为主。成熟-高成熟烃源岩也主要分布在滴水泉凹陷、东道海子—五彩湾凹陷和三南凹陷。

关键词：有效烃源灶有机质丰度有机质成熟度克拉美丽气田准噶尔盆地

全身免疫炎症指数、SYNTAX评分和脂蛋白a水平对老年冠心病患者PCI术后发生支架内再狭窄的评估价值

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广西医学 2024年第6期46卷 815-822页

作者：韦山龙曼云班华山黄锋柳州市人民医院老年病科广西柳州市545006 广西医科大学第一附属医院心血管内科广西南宁市530021

目的探讨全身免疫炎症指数(SII)、SYNTAX评分和脂蛋白a水平对老年冠心病患者经皮冠状动脉介入(PCI)术后发生支架内再狭窄(ISR)的评估价值。方法回顾性分析504例PCI术后复查冠状动脉造影(CAG)的老年冠心病患者的临床资料。根据PCI术后1... 详细信息

目的探讨全身免疫炎症指数(SII)、SYNTAX评分和脂蛋白a水平对老年冠心病患者经皮冠状动脉介入(PCI)术后发生支架内再狭窄(ISR)的评估价值。方法回顾性分析504例PCI术后复查冠状动脉造影(CAG)的老年冠心病患者的临床资料。根据PCI术后1年有无发生ISR,将患者分为非ISR组(n=410)和ISR组(n=94)。比较两组患者的一般资料、实验室指标、SII及SYNTAX评分。采用多因素Logistic回归模型分析老年冠心病患者PCI术后发生ISR的影响因素,绘制受试者工作特征(ROC)曲线分析SII、SYNTAX评分和脂蛋白a水平对老年冠心病患者PCI术后发生ISR的评估价值。结果共有94例患者发生ISR,发生率为18.7%。与非ISR组相比,ISR组患者的脉压差更大,慢性肾功能不全病史比例更高,SII、SYNTAX评分、白细胞计数及总胆固醇、脂蛋白a、HbA1c、纤维蛋白酶原、肌钙蛋白I水平更高(P<0.05)。多因素Logistic回归分析结果显示,高SII、高SYNTAX评分、高脂蛋白a水平是老年冠心病患者PCI术后发生ISR的独立危险因素(P<0.05)。ROC曲线分析结果显示,SII、SYNTAX评分、脂蛋白a水平及三者联合评估老年冠心病患者PCI术后发生ISR的曲线下面积分别为0.725、0.753、0.701、0.829,且三者联合的曲线下面积大于单一指标(P<0.05)。结论高SII、高SYNTAX评分、高脂蛋白a水平是老年冠心病患者PCI术后发生ISR的独立危险因素。SII、SYNTAX评分、脂蛋白a水平对老年冠心病患者PCI术后发生ISR具有一定的评估效能,且三者联合的评估效能更佳。

关键词：冠心病支架内再狭窄全身免疫炎症指数 SYNTAX评分脂蛋白a 经皮冠状动脉介入老年人

Thermometry strategy developed based on fluorescence contrast driven by varying excitations in codoped LiNbO3

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Photonics Research 2020年第2期8卷 135-142页

作者： SIWEI long SHAOPENG LIN DECAI MA YUNZHONG ZHU huashan LI BIAO WANG School of Physics Sun Yat-sen UniversityGuangzhou 510275China Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China

We propose what we believe is a novel optical thermometry strategy(FIR-Ex)based on the fluorescence intensity ratio(FIR)between two radiations associated with the same emission peak but different excitation wavelengths,in contrast to the traditional approach(FIR-Em),which depends on the FIR at varying emission *** temperature-dependent FIR within the FIR-Ex strategy arises from the different charge/energy evolution routes,rather than the distribution of thermally coupled levels within the FIR-Em *** diversity in thermal behaviors and luminescence mechanisms was demonstrated by analyzing the 618 nm red emission in Pr^3+-doped congruent LiNbO3(Pr:CLN)under 360 and 463 nm *** temperature sensitivity was further improved via Mg^2+ codoping due to the optimization of charge dynamics and energy transfer *** its wide detection scope,relatively high absolute sensitivity at low temperature,and high tunability of temperature sensitivity,the FIR-Ex strategy is promising for developing optical temperature-sensing materials with high performance.

关键词： LiNbO3 optical excitation

Deficiency of betaine-homocysteine methyltransferase activates glucose-6-phosphate dehydrogenase(G6PD)by decreasing arginine methylation of G6PD in hepatocellular carcinogenesis

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Science China(Life Sciences) 2024年第8期67卷 1648-1665页

作者： Jie Gao Xiaoyi Shi Yaohui Sun Xudong Liu Feng Zhang Chengcheng Shi Xiao Yu Zhiping Yan long Liu Shizhe Yu Jiacheng Zhang Xiaodan Zhang Shuijun Zhang Wenzhi Guo Department of Hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Henan Diagnosis&Treatment League for Hepatopathy The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Henan Innovative Research Group for Hepatobiliary&Pancreatic Surgery and Digestive Organ Transplantation Zhengzhou 450052China Henan Organ Transplantation Quality Control Centre Zhengzhou 450052China Henan Engineering Technology Research Center for Organ Transplantation Zhengzhou 450052China Department of Pharmacy The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of General Surgery Huashan HospitalFudan University Shanghai 200040China Cancer Metastasis Institute Fudan UniversityShanghai 200040China

Betaine-homocysteine methyltransferase(BHMT)regulates protein methylation and is correlated with tumorigenesis;however,the effects and regulation of BHMT in hepatocarcinogenesis remain largely ***,we determined the clinical significance of BHMT in the occurrence and progression of hepatocellular carcinoma(HCC)using tissue samples from 198 *** was to be frequently found(86.6%)expressed at relatively low levels in HCC tissues and was positively correlated with the overall survival of patients with *** overexpression effectively suppressed several malignant phenotypes in hepatoma cells in vitro and in vivo,whereas complete knockout of Bhmt(Bhmt^(−/−))produced the opposite *** combined proteomics,metabolomics,and molecular biological strategies and detected that Bhmt^(−/−)promoted hepatocarcinogenesis and tumor progression by enhancing the activity of glucose-6-phosphate dehydrogenase(G6PD)and PPP metabolism in DEN-induced HCC mouse and subcutaneous tumor-bearing *** contrast,restoration of Bhmt with an AAV8-Bhmt injection or pharmacological inhibition of G6PD attenuated ***,coimmunoprecipitation identified monomethylated modifications of the G6PD,and BHMT regulated the methylation of *** sequence analysis,generation and application of specific antibodies,and site-directed mutagenesis indicated G6PD methylation at the arginine residue ***,we established bidirectionally regulated BHMT cellular models combined with methylation-deficient G6PD mutants to demonstrate that BHMT potentiated arginine methylation of G6PD,thereby inhibiting G6PD activity,which in turn suppressed *** together,this study reveals a new methylation-regulatory mechanism in hepatocarcinogenesis owing to BHMT deficiency,suggesting a potential therapeutic strategy for HCC treatment.

关键词： HCC BHMT arginine methylation G6PD PPP metabolism

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U型平板微热管LED散热器散热性能分析

农业工程学报 2024年第9期40卷 227-235页

作者：余万韩煜王岗苏华山胡涛苏良彬董裴芹三峡大学水电机械设备设计与维护湖北省重点实验室宜昌443002 三峡大学机械与动力学院宜昌443002

针对目前LED表面发热量较大,局部温度过高,而导致其使用寿命减少的问题,该研究以平板微热管为核心传热元件,与锯齿形翅片结合,设计了一种U型平板微热管散热器。采用试验和仿真模拟相结合的方法,对不同风速、翅片结构、翅高及翅间距等关... 详细信息

针对目前LED表面发热量较大,局部温度过高,而导致其使用寿命减少的问题,该研究以平板微热管为核心传热元件,与锯齿形翅片结合,设计了一种U型平板微热管散热器。采用试验和仿真模拟相结合的方法,对不同风速、翅片结构、翅高及翅间距等关键影响因素进行分析。结果表明:通过对比分析U型平板微热管在两种室外工况下各测点试验值和模拟值,散热稳定后温度的最大误差分别为4.2%和6.7%,验证了模型的可靠性。风速分别为0.5和3.0 m/s时,锯齿型翅片都具有良好的散热性能。当风速为3.0 m/s时,锯齿型翅片、W型翅片、直翅片散热器稳定后热源温度分别为34.3、35.5和39.1℃。为找到最佳工况和结构,进行了正交分析,当室外风速为3.5 m/s,锯齿型翅片翅高为12 mm,翅间距为8 mm时,U型热管具有较佳的散热性能。研究结果可为LED散热系统的设计提供数据参考和设计思路,拓宽LED光源的应用范围。

关键词：数值模拟试验散热 U型平板微热管翅片正交分析

大学生英语词汇学习中的听读并行优势——基于投入量假设的实证研究

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韶关学院学报 2024年第5期45卷 21-26页

作者：裴涛鲁华山韶关学院外国语学院广东韶关512005 青岛农业大学外国语学院山东青岛266109

投入量假设(ILH)是词汇习得研究领域的研究焦点,但其有效性仍存争议。通过对比听读并行任务与阅读任务,考察不同任务投入量对二语学习者词汇学习的影响。126名英语中等水平的大学生分为4组,分别完成不同投入量的任务以学习目标假词:一... 详细信息

投入量假设(ILH)是词汇习得研究领域的研究焦点,但其有效性仍存争议。通过对比听读并行任务与阅读任务,考察不同任务投入量对二语学习者词汇学习的影响。126名英语中等水平的大学生分为4组,分别完成不同投入量的任务以学习目标假词:一组接受听读并行的输入模式,其余三组完成不同投入量的阅读任务(阅读/阅读+填空/阅读+翻译)。即时词汇量表用于检测学习者的词汇掌握程度,延时一周的访谈考察其对实验任务的看法。研究结果显示,听读并行任务的词汇学习有效性优于阅读任务,投入量假设部分预测该层次学习者对目标词汇的掌握程度。

关键词：投入量假设听读并行词汇附带习得任务类型实证研究