检索结果-南通市图书馆

中国式乡村文化振兴:理论内涵、价值耦合及未来进路

在线全文

学校读者我要写书评

暂无评论

东北师大学报（哲学社会科学版） 2024年第4期 49-58页

作者：刘丽伟华东政法大学商学院上海201620

中国式乡村文化振兴是中国式现代化新道路的重要构成。本文系统阐释了中国式乡村文化及中国式乡村文化振兴的深层次内涵,并从乡村农耕文化复兴与产业兴旺目标相耦合、乡村生态文化复兴与生态宜居目标相耦合、乡村伦理文化复兴与乡风文... 详细信息

中国式乡村文化振兴是中国式现代化新道路的重要构成。本文系统阐释了中国式乡村文化及中国式乡村文化振兴的深层次内涵,并从乡村农耕文化复兴与产业兴旺目标相耦合、乡村生态文化复兴与生态宜居目标相耦合、乡村伦理文化复兴与乡风文明目标相耦合、乡村自治文化复兴与治理有效目标相耦合、乡村文化整体振兴与生活富裕目标相耦合等五个方面剖析乡村文化振兴与乡村振兴间的价值耦合关系。在此基础上,本文围绕乡村文化振兴的现实困境,以新发展理念为逻辑引领,以高质量发展为阶段目标,从乡村文化振兴要以乡村为本、以农民为本,继承优秀乡村传统文化、重塑乡村文化的当代价值,促进城乡文化互动融合、存续“记得住的乡愁”,运用传统文化元素、创新乡村治理模式等四个方面提出了推动中国式乡村文化振兴的未来进路,以期开创新时代乡村文明新形态。

关键词：中国式乡村文化振兴理论内涵价值耦合未来进路

基于混合算法计算炸药JWL状态方程参数的研究

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

工程爆破 2024年第2期30卷 42-48,97页

作者：郝博刘力维姜琦东北大学机械工程与自动化学院辽宁沈阳110819 东北大学秦皇岛分校控制工程学院河北秦皇岛066004

JWL状态方程参数是炸药爆炸膨胀数值模拟仿真的基础,圆筒试验标定法复杂且成本很高,为了准确快速地获得炸药JWL状态方程参数,提出一种基于灰狼粒子群混合算法计算确定炸药JWL状态方程参数的方法。该方法仅把炸药的爆速和初始密度作为已... 详细信息

JWL状态方程参数是炸药爆炸膨胀数值模拟仿真的基础,圆筒试验标定法复杂且成本很高,为了准确快速地获得炸药JWL状态方程参数,提出一种基于灰狼粒子群混合算法计算确定炸药JWL状态方程参数的方法。该方法仅把炸药的爆速和初始密度作为已知条件即可计算确定JWL状态方程参数。基于此方法对TNT、PETN 1.77、HMX、PBX-9010、PBX-9501和OCTOL炸药的JWL状态方程参数进行计算,将计算所得参数进行圆筒试验数值仿真模拟,同时与标准参数仿真模拟结果进行对比,仿真结果曲线R 2分别为0.995681、0.999012、0.99999、0.999533、0.999069和0.998904,均大于0.99,说明计算方法可行,可为炸药JWL状态方程参数的获取研究工作提供一定参考。

关键词：炸药 JWL状态方程混合算法数值模拟

谷氨酸和α-酮戊二酸对鳜生长、脱氨及糖代谢的影响

在线全文

学校读者我要写书评

暂无评论

水生生物学报 2024年第3期48卷 384-392页

作者：杨儒张冬吴璐瑶胡兵陈加成李颜刘立维华中农业大学水产学院华中农业大学鳜鱼研究中心长江经济带大宗水生生物产业绿色发展教育部工程研究中心武汉430070 福建省特种水产配合饲料重点实验(福建天马科技集团股份有限公司) 福清350308

为探究谷氨酸(Glu)和α-酮戊二酸(AKG)对鳜(Siniperca chuatsi)摄食和氨排泄的影响,实验以鳜[初始体重(26.28±0.99)g]为研究材料,将Glu和AKG分别添加到鳜的基础日粮中(添加量2%),进行了60d的养殖实验,前40d等量投喂,后20d饱食投喂。通... 详细信息

为探究谷氨酸(Glu)和α-酮戊二酸(AKG)对鳜(Siniperca chuatsi)摄食和氨排泄的影响,实验以鳜[初始体重(26.28±0.99)g]为研究材料,将Glu和AKG分别添加到鳜的基础日粮中(添加量2%),进行了60d的养殖实验,前40d等量投喂,后20d饱食投喂。通过设置对照组、Glu组和AKG组,比较了3种不同饲料饲喂下鳜的摄食与氨排泄差异情况。实验结果表明,在等量饲喂期间添加Glu、AKG显著提高鳜生长和降低饵料系数,且在一定程度上降低鳜的体外氨排泄量。在饱食投喂阶段,Glu、AKG组的血液中的葡萄糖含量增加,肝糖原、肌糖原含量降低。两个投喂阶段结果都表明,饲料中添加谷氨酸和α-酮戊二酸能显著促进鳜脑中npy表达并抑制pomc表达,显著提高蛋白质效率比和特定生长率,增加鱼体体重,促进鱼体生长且降低饲料系数。同时,肝脏中gdh表达及肌肉ampd表达均提高,脱氨代谢供能水平升高,最终导致其氨排泄量升高。此外,饲料中添加Glu和AKG可促进肝脏pepck、g6pase、pk和gk基因表达量增加,糖代谢增强,减少蛋白质的分解供能。综上所述,在饲料中添加谷氨酸和α-酮戊二酸均能促进鳜的摄食并降低氨的排泄。研究结果将应用于鳜的低氨排放养殖,并推进谷氨酸和α-酮戊二酸在鳜饲料中的应用。

关键词：谷氨酸 α-酮戊二酸摄食氨排泄鳜

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

白藜芦醇减轻大鼠胰岛β细胞瘤细胞低氧损伤

营养学报 2024年第1期46卷 69-74页

作者：张岭郑桂玲厉彦超蒲玲玲刘伟丽陈照立军事科学院军事医学研究院环境医学与作业医学研究所天津300050 联勤保障部队第九八三医院天津300142 中国人民解放军32183部队医院白城137000

目的研究白藜芦醇减轻大鼠胰岛β细胞瘤细胞(INS-1)低氧损伤的作用。方法将INS-1细胞分为三组,即常氧对照组(control)、低氧组(hypoxia)、低氧及白藜芦醇组(hypoxia+RSV);采用正常培养方法培养常氧对照组,用CCK8检测不同低氧时间(6、12... 详细信息

目的研究白藜芦醇减轻大鼠胰岛β细胞瘤细胞(INS-1)低氧损伤的作用。方法将INS-1细胞分为三组,即常氧对照组(control)、低氧组(hypoxia)、低氧及白藜芦醇组(hypoxia+RSV);采用正常培养方法培养常氧对照组,用CCK8检测不同低氧时间(6、12、24、48 h)的细胞增殖情况,选择合适的时间条件构建低氧模型并用于下一步研究;再以不同浓度的白藜芦醇(8、10、12、15μmol/L)提前干预12 h,并进行前期设定的低氧条件处理,用CCK8检测合适的浓度条件,构建白藜芦醇干预模型并用于下一步研究。以组织活性氧试剂盒及线粒体超氧化物试剂盒检测氧化应激水平;线粒体膜电位及ATP水平检测线粒体功能;流式细胞仪分析检测凋亡;胰岛素定量检测试剂盒检测胰岛素分泌量;实时定量反转录检测Sirt1、Pdx1、Glut2的表达水平;蛋白免疫印迹检测相应蛋白水平。结果与常氧对照组相比,低氧组细胞增殖降低(P<0.05),细胞凋亡率增加(P<0.01),线粒体功能降低(P<0.05),胰岛素分泌减少(P<0.05),Sirt1、Pdx1、Glut2基因及其相应蛋白表达水平降低(P<0.05)。而白藜芦醇干预可以明显减轻低氧应激损伤(P<0.05),促进增殖(P<0.05),逆转凋亡(P<0.01),改善线粒体功能(P<0.05),促进胰岛素分泌(P<0.05),促进Sirt1、Pdx1、Glut2基因及其相应蛋白表达水平(P<0.05)。结论白藜芦醇可以保护低氧造成的INS-1细胞氧化应激损伤,改善线粒体功能,抗凋亡,并促进胰岛素功能性基因表达,促进胰岛素分泌。

关键词：白藜芦醇低氧大鼠胰岛β细胞瘤系INS-1细胞

Tidal current turbine based on hydraulic transmission system

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第7期12卷 511-518页

作者： Hong-wei liu wei li Yong-gang liN Shun MA State Key Laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China

Tidal current turbines(TCTs) are newly developed electricity generating *** at the stabilization of the power output of TCTs,this paper introduces the hydraulic transmission technologies into *** hydrodynamics of the turbine was analyzed at first and its power output characteristics were predicted.A hydraulic power transmission system and a hydraulic pitch-controlled system were *** related simulations were ***,a TCT prototype was manufactured and tested in the *** test results have confirmed the correctness of the current design and availability of installation of the hydraulic system in TCTs.

关键词： Tidal current turbines(TCTs) Hydraulic power transmission Hydraulic pitch-controlled system Workshop test

Estimation of interfacial damage in composites with reinforced particles based on ultrasonic data

在线全文

学校读者我要写书评

暂无评论

Journal of University of Science and Technology Beijing 2007年第3期14卷 280-285页

作者： Xiqiang liu Peijun wei li Zhang Hang Wang Applied Science School University of Science and Technology Beijing Beijing 100083 China

The scattering of elastic waves by a spherical particle with imperfect interface and the nondestructive detection of interfacial damage were studied. First, the scattering of elastic waves by a spherical particle with imperfect interface, i.e. spring interface model, was studied. Then, multiple scattering by random distributed particles was investigated and the equations to evaluate the velocity and attenuation of effective waves defined by statistic averaging were given. Furthermore, on the basis of the established relation between the velocity and interfacial constants, a method to evaluate the interfacial damage nondestructively from the ultrasonic data was pro- posed. Numerical simulation was performed for the SiC-Al composites. The velocities of the effective waves were computed to show the influence of the interface constants. Using the genetic algorithm, the interfacial damage was evaluated from the synthetic experi- mental data with various noise levels. The numerical results showed the feasibility of the method proposed.

关键词： spring model average waves scattering genetic algorithm inverse problem

Mechanical properties of electroformed copper layers with gradient microstructure

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2010年第1期17卷 69-74页

作者： Qiang liao li-qun Zhu Hui-cong liu wei-ping li School of Materials Science and Engineering Beihang University Beij ing 100191 China

The electroformed copper layer with gradient microstructure was prepared using the ultrasonic technique. The microstructure of the electroformed copper layer was observed by using an optical microscope （OM） and a scanning electron microscope （SEM）. The preferred orientations of the layer were characterized by X-ray diffraction （XRD）. The mechanical properties were evaluated with a Vicker＇s hardness tester and a tensile tester. It is found the gradient microstructure consists of two main parts： the outer part （faraway substrate） with columnar crystals and the inner part （nearby substrate） with equiaxed grains. The Cu-（220） preferred orientation increases with the increasing thickness of the copper layer. The test results show that the microhardness of the electroformed copper layer decreases with increasing grain size along the growth direction and presents a gradient distribution. The tensile strength of the outer part of the electroformed copper layer is higher than that of the inner part but at the cost of ductility. Meanwhile, the integral mechanical properties of the electroformed copper with gradient microstrucmre are significantly improved in comparison with the pure copper deposit.

关键词： electroforming copper layer gradient rnicrostructure mechanical properties preferred orientation

The Distribution of DEN Infected People in Dushan and Xingyi Area of Yunnan-Guizhou Plateau,China

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2006年第6期3卷 473-476页

作者： wei liu li ZUO Yongbing Zhou Department of Immunology Guiyang Medical College Guiyang 550004 Guizhou China

The dengue viruses （DEN, genus Flavivirus, family Flaviviridae） are mosquito borne and have caused 100 million cases of dengue fever each year in most tropical and subtropical areas of the world. However, in the Southwest area of Yunnan-Guizhou Plateau, China, the previous work demonstrated that different geographic strains of Aedes albopictus were susceptible to dengue virus. In this study, we collected 456 sera samples from patients with fever and 994 sera samples from healthy population in Dushan and Xingyi area of Yunnan-Guizhou Plateau, China. All sera samples were tested for dengue IgG by enzyme-linked immunosorbent assay （EliSA）. Patients＇ sera samples were tested for dengue IgM and DEN antigen was checked in the sera of 6 from 456 samples with which C6/36 cell in culated by IFA. The results indicate that these patients with fever were infected with DEN-2 and suggest that DEN infection had existed in Dushan and Xingyi area of Yunnan-Guizhou Plateau, China.

关键词： dengue virus DHF IFA

Phosphatase and tensin homolog gene inhibits the effect induced by gonadotropin-releasing hormone subtypes in human endometrial carcinoma cells

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2010年第9期123卷 1170-1175页

作者： ZHAO li-jun liu Ning li Xiao-ping WANG Jian-liu wei li-hui Department of Obstetrics & Gynecology Peking University People's Hospital100044BeijingChina

Background Type I gonadotropin-releasing hormone （GnRH-l） agonists have been applied for the treatment of steroid-dependent tumors such as breast carcinoma, ovarian cancer and prostatic carcinoma. But the mechanism has not been clarified yet. There are few reports about the treatment of endometrial carcinoma using GnRH-l agonists. Type II GnRH （GnRH-ll） is a new subtype of GnRH. Our aim was to investigate the effects of GnRH-l agonists and GnRH-ll on estrogen receptor-negative human endometrial carcinoma cells and the effect from phosphatase and tensin homolog gene （PTEN） to *** A lentiviral vector-mediated RNAi method was used to establish a PTEN-negative HEC-1A cell clone （HEC-1A-ND）. MTT and flow cytometry were used to detect the cell proliferation, cell cycle and apoptosis of HEC-1A, HEC-1A-NC and HEC-1A-ND cells after treatment with GnRH-l agonist Triptorelin （10-11 mol/L to 10-5 mol/L） or GnRH-ll （10-11 mol/L to 10-5 mol/L）. Western blotting was used to detect AKT and ERK1/2 activation after treatment with different concentrations of Triptorelin or GnRH-ll for 30 minutes in the above mentioned three kinds of cells. Results Triptorelin and GnRH-ll induced apoptosis and inhibited proliferation of HEC-1 A, HEC-1A-ND and HEC-1A-NC in a dose-dependent manner. This effect was augmented in HEC-1 A-ND cells in which PTEN gene was knocked-down. Furthermore, Triptorelin and GnRH-ll inhibited the AKT and ERK activity in HEC-1 A-ND *** Triptorelin and GnRH-ll can promote apoptosis rate and inhibit cell proliferation of estrogen receptor-negative endometrial carcinoma cells in a dose-dependent manner. PTEN gene can inhibit the effects of Triptorelin or GnRH-ll on human endometrial carcinoma cells.

关键词： human endometrial carcinoma gonadotropin-releasing hormone-I agonist estrogen receptor